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NANOG | Homeobox domain-containing protein. (300 aa) | ||||
CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa) | ||||
LOC102181148 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa) | ||||
LOC102180290 | USP domain-containing protein; Belongs to the peptidase C19 family. (349 aa) | ||||
TLR2 | Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (794 aa) | ||||
LOC102180168 | Uncharacterized protein; Belongs to the alkaline phosphatase family. (531 aa) | ||||
KITLG | Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. (274 aa) | ||||
LOC108633351 | Uncharacterized protein; Belongs to the alkaline phosphatase family. (531 aa) | ||||
LOC102190650 | Uncharacterized protein; Belongs to the alkaline phosphatase family. (528 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) | ||||
LOC102182683 | C-X-C motif chemokine. (109 aa) | ||||
CCL2 | C-C motif chemokine. (98 aa) | ||||
PAX6 | Paired box 6. (486 aa) | ||||
GAPDH | Glyceraldehyde-3-phosphate dehydrogenase. (333 aa) | ||||
POU5F1 | POU domain protein. (360 aa) | ||||
BMP4 | Bone morphogenetic protein 4. (409 aa) | ||||
IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) | ||||
SOX17 | SRY-box transcription factor 17. (410 aa) | ||||
LOC102190919 | Alkaline phosphatase. (530 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (770 aa) | ||||
ALB | Serum albumin. (608 aa) | ||||
TLR4 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (841 aa) | ||||
IRF3 | Interferon regulatory factor 3. (418 aa) | ||||
LOC102190507 | Uncharacterized protein. (139 aa) | ||||
IL10 | Interleukin 10. (177 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa) | ||||
PXDN | Peroxidasin. (1525 aa) | ||||
CD86 | Ig-like domain-containing protein. (289 aa) | ||||
CD163 | CD163 molecule. (1114 aa) | ||||
CXCL10 | C-X-C motif chemokine. (102 aa) | ||||
MSX1 | Msh homeobox 1. (303 aa) | ||||
CASP1 | Uncharacterized protein; Belongs to the peptidase C14A family. (411 aa) | ||||
ACTB | Uncharacterized protein. (375 aa) | ||||
NCK1 | Cytoplasmic protein. (377 aa) | ||||
IL6R | Interleukin 6 receptor. (441 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa) | ||||
ALPL | Alkaline phosphatase. (524 aa) | ||||
LOC102179897 | Alkaline phosphatase. (530 aa) | ||||
BCL10 | BCL10 immune signaling adaptor. (230 aa) | ||||
ENSCHIP00000007600 | Uncharacterized protein. (352 aa) | ||||
CD4 | CD4 molecule. (455 aa) | ||||
NCK2 | Cytoplasmic protein. (376 aa) | ||||
LOC102190876 | Alkaline phosphatase. (530 aa) | ||||
CD80 | CD80 molecule. (302 aa) | ||||
ZNF7 | Zinc finger protein 7. (675 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) | ||||
AFP | Alpha fetoprotein. (610 aa) | ||||
CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa) |