(39 nodes) (2023) Lineage tracing of newly accrued nuclei in skeletal myofibers uncovers distinct transcripts and interplay between nuclear populations. network (Capra hircus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYOG	Myogenin. (224 aa)
	MYH7	Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1955 aa)
	KLHL41	Kelch like family member 41. (606 aa)
	LOC102174895	Uncharacterized protein. (735 aa)
	LOC108633295	ZZ-type domain-containing protein. (323 aa)
	ENAH	ENAH actin regulator. (800 aa)
	MAF	MAF bZIP transcription factor; Belongs to the bZIP family. (404 aa)
	DCLK1	Doublecortin like kinase 1. (741 aa)
	LRRTM3	Leucine rich repeat transmembrane neuronal 3. (581 aa)
	PAX7	Paired box 7. (503 aa)
	DLG2	Discs large MAGUK scaffold protein 2. (901 aa)
	ATP2A2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1026 aa)
	MYH2	Myosin heavy chain 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1936 aa)
	UTRN	Utrophin. (3404 aa)
	KCNN2	Potassium calcium-activated channel subfamily N member 2. (852 aa)
	DPP6	Dipeptidyl peptidase like 6; Belongs to the peptidase S9B family. (868 aa)
	MYLK4	Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (387 aa)
	POSTN	Periostin. (836 aa)
	XIRP2	Xin actin binding repeat containing 2. (3752 aa)
	MYH8	Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
	MYH4	Myosin heavy chain 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1931 aa)
	ANKRD2	Ankyrin repeat domain 2. (329 aa)
	TPM2	Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
	ATF3	Activating transcription factor 3. (181 aa)
	RUNX1	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (453 aa)
	BTG4	BTG anti-proliferation factor 4. (229 aa)
	TPM3	Tropomyosin 3; Belongs to the tropomyosin family. (290 aa)
	CPNE4	Copine domain-containing protein. (108 aa)
	ANKRD1	Ankyrin repeat domain 1. (319 aa)
	ALB	Serum albumin. (608 aa)
	COL12A1	Collagen type XII alpha 1 chain. (3046 aa)
	TPM1	Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
	MYH3	Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
	TNNT2	Troponin T2, cardiac type. (267 aa)
	IGF2	Insulin-like growth factor II. (179 aa)
	FLNC	Filamin C. (2720 aa)
	TNNT1	Troponin T1, slow skeletal type. (252 aa)
	COL1A1	Collagen type I alpha 1 chain. (1463 aa)
	FBN1	Fibrillin 1. (2860 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	ATF3	ENSCHIP00000020234	ENSCHIP00000014267	Serum albumin.	Activating transcription factor 3.	0.502
ALB	COL1A1	ENSCHIP00000020234	ENSCHIP00000023918	Serum albumin.	Collagen type I alpha 1 chain.	0.696
ALB	IGF2	ENSCHIP00000020234	ENSCHIP00000023369	Serum albumin.	Insulin-like growth factor II.	0.716
ALB	LOC102174895	ENSCHIP00000020234	ENSCHIP00000024875	Serum albumin.	Uncharacterized protein.	0.759
ALB	LOC108633295	ENSCHIP00000020234	ENSCHIP00000025087	Serum albumin.	ZZ-type domain-containing protein.	0.619
ALB	MYOG	ENSCHIP00000020234	ENSCHIP00000023943	Serum albumin.	Myogenin.	0.679
ALB	PAX7	ENSCHIP00000020234	ENSCHIP00000027759	Serum albumin.	Paired box 7.	0.668
ALB	POSTN	ENSCHIP00000020234	ENSCHIP00000004170	Serum albumin.	Periostin.	0.505
ALB	RUNX1	ENSCHIP00000020234	ENSCHIP00000016603	Serum albumin.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.408
ALB	TNNT2	ENSCHIP00000020234	ENSCHIP00000022908	Serum albumin.	Troponin T2, cardiac type.	0.567
ALB	UTRN	ENSCHIP00000020234	ENSCHIP00000002137	Serum albumin.	Utrophin.	0.402
ANKRD1	MYH7	ENSCHIP00000019764	ENSCHIP00000024142	Ankyrin repeat domain 1.	Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.638
ANKRD1	MYH8	ENSCHIP00000019764	ENSCHIP00000006916	Ankyrin repeat domain 1.	Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.447
ANKRD1	TNNT2	ENSCHIP00000019764	ENSCHIP00000022908	Ankyrin repeat domain 1.	Troponin T2, cardiac type.	0.457
ANKRD2	KLHL41	ENSCHIP00000008553	ENSCHIP00000024642	Ankyrin repeat domain 2.	Kelch like family member 41.	0.400
ANKRD2	MYOG	ENSCHIP00000008553	ENSCHIP00000023943	Ankyrin repeat domain 2.	Myogenin.	0.459
ANKRD2	TPM3	ENSCHIP00000008553	ENSCHIP00000017836	Ankyrin repeat domain 2.	Tropomyosin 3; Belongs to the tropomyosin family.	0.458
ATF3	ALB	ENSCHIP00000014267	ENSCHIP00000020234	Activating transcription factor 3.	Serum albumin.	0.502
ATF3	MAF	ENSCHIP00000014267	ENSCHIP00000026088	Activating transcription factor 3.	MAF bZIP transcription factor; Belongs to the bZIP family.	0.424
ATF3	RUNX1	ENSCHIP00000014267	ENSCHIP00000016603	Activating transcription factor 3.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.455