10 items (Capra hircus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Your Input:
	BCHE	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (674 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (487 aa)
	GOT1	Aspartate aminotransferase. (413 aa)
	ACLY	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1101 aa)
	PC	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1187 aa)
	ALB	Serum albumin. (608 aa)
	PEMT	Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. (199 aa)
	PAH	Phenylalanine hydroxylase. (466 aa)
	GOT2	Aspartate aminotransferase. (430 aa)
	LDH-A	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLY	GOT1	ENSCHIP00000027213	ENSCHIP00000029101	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Aspartate aminotransferase.	0.879
ACLY	GOT2	ENSCHIP00000027213	ENSCHIP00000010968	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Aspartate aminotransferase.	0.884
ACLY	LDH-A	ENSCHIP00000027213	ENSCHIP00000019303	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.685
ACLY	LPL	ENSCHIP00000027213	ENSCHIP00000031249	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.409
ACLY	PC	ENSCHIP00000027213	ENSCHIP00000025566	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.970
ALB	BCHE	ENSCHIP00000020234	ENSCHIP00000033062	Serum albumin.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.808
ALB	GOT1	ENSCHIP00000020234	ENSCHIP00000029101	Serum albumin.	Aspartate aminotransferase.	0.972
ALB	GOT2	ENSCHIP00000020234	ENSCHIP00000010968	Serum albumin.	Aspartate aminotransferase.	0.954
ALB	LDH-A	ENSCHIP00000020234	ENSCHIP00000019303	Serum albumin.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.817
ALB	LPL	ENSCHIP00000020234	ENSCHIP00000031249	Serum albumin.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.587
BCHE	ALB	ENSCHIP00000033062	ENSCHIP00000020234	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Serum albumin.	0.808
BCHE	GOT1	ENSCHIP00000033062	ENSCHIP00000029101	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Aspartate aminotransferase.	0.705
BCHE	GOT2	ENSCHIP00000033062	ENSCHIP00000010968	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Aspartate aminotransferase.	0.704
GOT1	ACLY	ENSCHIP00000029101	ENSCHIP00000027213	Aspartate aminotransferase.	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	0.879
GOT1	ALB	ENSCHIP00000029101	ENSCHIP00000020234	Aspartate aminotransferase.	Serum albumin.	0.972
GOT1	BCHE	ENSCHIP00000029101	ENSCHIP00000033062	Aspartate aminotransferase.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.705
GOT1	GOT2	ENSCHIP00000029101	ENSCHIP00000010968	Aspartate aminotransferase.	Aspartate aminotransferase.	0.983
GOT1	LDH-A	ENSCHIP00000029101	ENSCHIP00000019303	Aspartate aminotransferase.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.992
GOT1	PAH	ENSCHIP00000029101	ENSCHIP00000018855	Aspartate aminotransferase.	Phenylalanine hydroxylase.	0.947
GOT1	PC	ENSCHIP00000029101	ENSCHIP00000025566	Aspartate aminotransferase.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.920