(14 nodes) (2023) The m6A reader YTHDC1-mediated lncRNA CTBP1-AS2 m6A modification accelerates cholangiocarcinoma progression. network (Capra hircus)

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Your Input:
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	METTL14	Methyltransferase like 14; Belongs to the MT-A70-like family. (456 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
	CTBP1	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	ALKBH5	AlkB homolog 5, RNA demethylase. (394 aa)
	YTHDC1	YTH domain containing 1. (698 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
	FTO	Fat mass and obesity associated protein. (505 aa)
	E2F3	E2F_TDP domain-containing protein. (460 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	CCNB1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (427 aa)
	BCL2	BH4_2 domain-containing protein. (229 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALKBH5	FTO	ENSCHIP00000033881	ENSCHIP00000004985	AlkB homolog 5, RNA demethylase.	Fat mass and obesity associated protein.	0.990
ALKBH5	GAPDH	ENSCHIP00000033881	ENSCHIP00000025974	AlkB homolog 5, RNA demethylase.	Glyceraldehyde-3-phosphate dehydrogenase.	0.660
ALKBH5	METTL14	ENSCHIP00000033881	ENSCHIP00000029615	AlkB homolog 5, RNA demethylase.	Methyltransferase like 14; Belongs to the MT-A70-like family.	0.967
ALKBH5	YTHDC1	ENSCHIP00000033881	ENSCHIP00000002274	AlkB homolog 5, RNA demethylase.	YTH domain containing 1.	0.915
BCL2	CCNB1	ENSCHIP00000015831	ENSCHIP00000015792	BH4_2 domain-containing protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.810
BCL2	CTNNB1	ENSCHIP00000015831	ENSCHIP00000031016	BH4_2 domain-containing protein.	Catenin beta 1.	0.820
BCL2	E2F3	ENSCHIP00000015831	ENSCHIP00000007013	BH4_2 domain-containing protein.	E2F_TDP domain-containing protein.	0.491
BCL2	GAPDH	ENSCHIP00000015831	ENSCHIP00000025974	BH4_2 domain-containing protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.941
BCL2	PTEN	ENSCHIP00000015831	ENSCHIP00000002897	BH4_2 domain-containing protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.842
BCL2	SMAD2	ENSCHIP00000015831	ENSCHIP00000022106	BH4_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.640
BCL2	SMAD3	ENSCHIP00000015831	ENSCHIP00000011729	BH4_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.637
BCL2	TP53	ENSCHIP00000015831	ENSCHIP00000030141	BH4_2 domain-containing protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.999
CCNB1	BCL2	ENSCHIP00000015792	ENSCHIP00000015831	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	BH4_2 domain-containing protein.	0.810
CCNB1	CTNNB1	ENSCHIP00000015792	ENSCHIP00000031016	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Catenin beta 1.	0.651
CCNB1	E2F3	ENSCHIP00000015792	ENSCHIP00000007013	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	E2F_TDP domain-containing protein.	0.418
CCNB1	GAPDH	ENSCHIP00000015792	ENSCHIP00000025974	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.842
CCNB1	PTEN	ENSCHIP00000015792	ENSCHIP00000002897	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.630
CCNB1	TP53	ENSCHIP00000015792	ENSCHIP00000030141	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.914
CTBP1	CTNNB1	ENSCHIP00000030551	ENSCHIP00000031016	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Catenin beta 1.	0.931
CTBP1	GAPDH	ENSCHIP00000030551	ENSCHIP00000025974	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.537