STRINGSTRING
SWSAP1 SWSAP1 FIGNL1 FIGNL1 ZBTB16 ZBTB16 RAD52 RAD52 PALB2 PALB2 MEIOB MEIOB RTEL1 RTEL1 MCM8 MCM8 RAD51B RAD51B WRN WRN FANCM FANCM RAD51C RAD51C SPAST SPAST STRA8 STRA8 FBH1 FBH1 SPIDR SPIDR ALB ALB SYCP1 SYCP1 BRCA2 BRCA2 TRIP13 TRIP13 MCMDC2 MCMDC2 SPO11 SPO11 XRCC2 XRCC2 SYCP3 SYCP3 MSH4 MSH4 SPATA22 SPATA22
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SWSAP1SWIM-type zinc finger 7 associated protein 1. (250 aa)
FIGNL1Fidgetin like 1; Belongs to the AAA ATPase family. (677 aa)
ZBTB16Uncharacterized protein. (673 aa)
RAD52RAD52 homolog, DNA repair protein. (416 aa)
PALB2Partner and localizer of BRCA2. (1194 aa)
MEIOBMeiosis specific with OB-fold. (467 aa)
RTEL1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1212 aa)
MCM8MCM domain-containing protein; Belongs to the MCM family. (832 aa)
RAD51BRAD51 paralog B. (270 aa)
WRNWRN RecQ like helicase. (1405 aa)
FANCMFA complementation group M. (2043 aa)
RAD51CRAD51 paralog C. (371 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (614 aa)
STRA8Stimulated by retinoic acid 8. (447 aa)
FBH1F-box DNA helicase 1. (1048 aa)
SPIDRScaffold protein involved in DNA repair. (916 aa)
ALBSerum albumin. (608 aa)
SYCP1Synaptonemal complex protein 1. (918 aa)
BRCA2BRCA2 DNA repair associated. (3405 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (432 aa)
MCMDC2Minichromosome maintenance domain containing 2. (681 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (395 aa)
XRCC2X-ray repair cross complementing 2. (280 aa)
SYCP3Synaptonemal complex protein 3. (229 aa)
MSH4MutS homolog 4. (930 aa)
SPATA22Spermatogenesis associated 22. (364 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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