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RPL13A RPL13A ATP5PF ATP5PF HSP90AA1 HSP90AA1 NDUFV1 NDUFV1 NDUFB3 NDUFB3 TOMM40 TOMM40 DNM1L DNM1L TIMM44 TIMM44 NDUFS2 NDUFS2 TP53 TP53 LOC102173997 LOC102173997 CDKN2A CDKN2A NDUFV3 NDUFV3 LOC106501717 LOC106501717 TOMM22 TOMM22 CS CS COX2 COX2 NDUFA1 NDUFA1 SDHD SDHD TIMM50 TIMM50 SLC25A19 SLC25A19 TOMM20 TOMM20 SLC25A2 SLC25A2 B2M B2M BCS1L BCS1L SOD2 SOD2 COX10 COX10 BBC3 BBC3 ATP5F1B ATP5F1B TIMM17A TIMM17A IMMP1L IMMP1L NDUFA3 NDUFA3 ATP5PB ATP5PB SDHB SDHB ACTB ACTB NDUFB7 NDUFB7 CPT2 CPT2 NDUFB8 NDUFB8 COX7A2L COX7A2L NDUFA10 NDUFA10 TFAM TFAM ATP5F1A ATP5F1A UQCRFS1 UQCRFS1 SIRT3 SIRT3 HIF1A HIF1A HPRT1 HPRT1 TIMM22 TIMM22 NDUFC1 NDUFC1 BAK1 BAK1 UCP2 UCP2 UQCRC2 UQCRC2 LHPP LHPP NDUFS3 NDUFS3 SLC25A31 SLC25A31 NDUFB10 NDUFB10 ATP5MC3 ATP5MC3 ATP5F1C ATP5F1C LOC102168547 LOC102168547 COX6A2 COX6A2 ATP4A ATP4A NDUFA11 NDUFA11 MIPEP MIPEP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPL13AUncharacterized protein; Belongs to the universal ribosomal protein uL13 family. (203 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (733 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
NDUFB3NADH:ubiquinone oxidoreductase subunit B3. (98 aa)
TOMM40Translocase of outer mitochondrial membrane 40. (361 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (707 aa)
TIMM44Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (454 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (463 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
LOC102173997Capra hircus breed Kapro cytochrome c mRNA; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (157 aa)
NDUFV3Uncharacterized protein. (109 aa)
LOC106501717Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TOMM22Translocase of outer mitochondrial membrane 22. (142 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (454 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (227 aa)
NDUFA1NADH:ubiquinone oxidoreductase subunit A1. (70 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
TIMM50Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (355 aa)
SLC25A19Solute carrier family 25 member 19; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)
TOMM20Translocase of outer mitochondrial membrane 20. (145 aa)
SLC25A2Solute carrier family 25 member 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (301 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (124 aa)
BCS1LBCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (419 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
COX10Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family. (443 aa)
BBC3Uncharacterized protein. (193 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
TIMM17AMitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (171 aa)
IMMP1LMitochondrial inner membrane protease subunit. (166 aa)
NDUFA3Uncharacterized protein. (84 aa)
ATP5PBATP synthase peripheral stalk-membrane subunit b. (256 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
ACTBUncharacterized protein. (375 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (137 aa)
CPT2Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (658 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (114 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (355 aa)
TFAMTranscription factor A, mitochondrial. (246 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (560 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (333 aa)
HIF1AUncharacterized protein. (823 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
TIMM22Translocase of inner mitochondrial membrane 22. (194 aa)
NDUFC1Uncharacterized protein. (76 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
UCP2Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
UQCRC2Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa)
LHPPPhospholysine phosphohistidine inorganic pyrophosphate phosphatase. (270 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (266 aa)
SLC25A31Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (176 aa)
ATP5MC3ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (141 aa)
ATP5F1CATP synthase subunit gamma. (298 aa)
LOC102168547Beta-2-microglobulin. (124 aa)
COX6A2Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1034 aa)
NDUFA11Uncharacterized protein. (141 aa)
MIPEPMitochondrial intermediate peptidase. (707 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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