STRINGSTRING
COL4A2 COL4A2 COL5A3 COL5A3 COL1A2 COL1A2 FOS FOS SIX1 SIX1 CHODL CHODL EBF2 EBF2 ITGA7 ITGA7 SHH SHH PAX7 PAX7 FGFR4 FGFR4 PAX6 PAX6 PAX3 PAX3 LMNA LMNA NFIX NFIX COL4A1 COL4A1 RBPJ RBPJ EYA1 EYA1 LOC108633295 LOC108633295 HEY1 HEY1 CD44 CD44 MYH7 MYH7 POU5F1 POU5F1 MYOG MYOG FBN1 FBN1 COL1A1 COL1A1 JAG1 JAG1 EGFR EGFR MYH3 MYH3 SOX10 SOX10 CAV1 CAV1 PARD3 PARD3 TFAP2A TFAP2A COL6A2 COL6A2 PRDM16 PRDM16 B3GAT1 B3GAT1 EN1 EN1 NOTCH3 NOTCH3 TTN TTN PCNA PCNA CD82 CD82 NFIC NFIC MYF5 MYF5 MSX1 MSX1 ERBB3 ERBB3 MEOX2 MEOX2 CXCR4 CXCR4 HEYL HEYL TBX6 TBX6 TOP2A TOP2A COL5A2 COL5A2 TSC22D1 TSC22D1 NFIB NFIB TBX18 TBX18 NFIA NFIA FGFR1 FGFR1 SIM1 SIM1 MYH8 MYH8 OLIG3 OLIG3 PITX2 PITX2 NRARP NRARP MYOD1 MYOD1 UNCX UNCX DLX5 DLX5 CD9 CD9 POSTN POSTN FOXB1 FOXB1 EZH2 EZH2 CD34 CD34 PDGFRA PDGFRA JUN JUN POU4F1 POU4F1 PLAGL1 PLAGL1 DEK DEK COL15A1 COL15A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COL4A2Collagen type IV alpha 2 chain. (1607 aa)
COL5A3Collagen type V alpha 3 chain. (1455 aa)
COL1A2Collagen type I alpha 2 chain. (1128 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
SIX1SIX homeobox 1. (284 aa)
CHODLChondrolectin. (273 aa)
EBF2EBF transcription factor 2. (575 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
PAX7Paired box 7. (503 aa)
FGFR4Fibroblast growth factor receptor. (870 aa)
PAX6Paired box 6. (486 aa)
PAX3Paired box 3. (484 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (665 aa)
NFIXNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (503 aa)
COL4A1Collagen type IV alpha 1 chain. (1608 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (513 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (618 aa)
LOC108633295ZZ-type domain-containing protein. (323 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
CD44CD44 molecule (Indian blood group). (715 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1955 aa)
POU5F1POU domain protein. (360 aa)
MYOGMyogenin. (224 aa)
FBN1Fibrillin 1. (2860 aa)
COL1A1Collagen type I alpha 1 chain. (1463 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
EGFRReceptor protein-tyrosine kinase. (1208 aa)
MYH3Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
SOX10SRY-box transcription factor 10. (469 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
PARD3Par-3 family cell polarity regulator. (1351 aa)
TFAP2ATranscription factor AP-2 alpha. (485 aa)
COL6A2Collagen type VI alpha 2 chain. (1027 aa)
PRDM16PR/SET domain 16. (1271 aa)
B3GAT1Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (383 aa)
EN1Homeobox protein engrailed-like. (402 aa)
NOTCH3Notch receptor 3. (2332 aa)
TTNUncharacterized protein. (2149 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
CD82Tetraspanin. (265 aa)
NFICNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (506 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (260 aa)
MSX1Msh homeobox 1. (303 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1344 aa)
MEOX2Mesenchyme homeobox 2. (303 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
TBX6T-box transcription factor 6. (437 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1538 aa)
COL5A2Collagen type V alpha 2 chain. (1252 aa)
TSC22D1TSC22 domain family member 1. (1058 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
TBX18T-box transcription factor 18. (612 aa)
NFIANuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (509 aa)
FGFR1Fibroblast growth factor receptor. (860 aa)
SIM1SIM bHLH transcription factor 1. (766 aa)
MYH8Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
OLIG3Oligodendrocyte transcription factor 3. (272 aa)
PITX2Homeobox protein. (325 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
UNCXUNC homeobox. (522 aa)
DLX5Distal-less homeobox 5. (289 aa)
CD9Tetraspanin. (226 aa)
POSTNPeriostin. (836 aa)
FOXB1Forkhead box B1. (325 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
CD34Uncharacterized protein. (384 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1108 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa)
POU4F1POU domain protein. (421 aa)
PLAGL1PLAG1 like zinc finger 1. (460 aa)
DEKDEK proto-oncogene. (378 aa)
COL15A1Collagen type XV alpha 1 chain. (1375 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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