18 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GLUD1	ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (561 aa)
	OTC	Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (277 aa)
	NAGS	N-acetylglutamate synthase. (534 aa)
	GLS	Glutaminase. (673 aa)
	GOT2	Aspartate aminotransferase. (430 aa)
	NOS3	Nitric oxide synthase; Produces nitric oxide (NO). (1193 aa)
	GOT1L1	Glutamic-oxaloacetic transaminase 1 like 1. (404 aa)
	ASL	Uncharacterized protein. (473 aa)
	ACY1	M20_dimer domain-containing protein. (408 aa)
	GPT	Glutamic--pyruvic transaminase. (496 aa)
	ARG2	Arginase. (354 aa)
	ARG1	Arginase. (322 aa)
	NOS2	Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1154 aa)
	GOT1	Aspartate aminotransferase. (413 aa)
	CPS1	Carbamoyl-phosphate synthase 1. (1500 aa)
	GLUL	Glutamine synthetase. (373 aa)
	NOS1	Nitric oxide synthase 1. (1468 aa)
	GPT2	Glutamic--pyruvic transaminase 2. (523 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACY1	ARG1	ENSCHIP00000015762	ENSCHIP00000025258	M20_dimer domain-containing protein.	Arginase.	0.920
ACY1	ARG2	ENSCHIP00000015762	ENSCHIP00000017404	M20_dimer domain-containing protein.	Arginase.	0.920
ACY1	ASL	ENSCHIP00000015762	ENSCHIP00000014908	M20_dimer domain-containing protein.	Uncharacterized protein.	0.513
ACY1	CPS1	ENSCHIP00000015762	ENSCHIP00000030166	M20_dimer domain-containing protein.	Carbamoyl-phosphate synthase 1.	0.431
ACY1	NAGS	ENSCHIP00000015762	ENSCHIP00000003702	M20_dimer domain-containing protein.	N-acetylglutamate synthase.	0.401
ACY1	OTC	ENSCHIP00000015762	ENSCHIP00000003494	M20_dimer domain-containing protein.	Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	0.971
ARG1	ACY1	ENSCHIP00000025258	ENSCHIP00000015762	Arginase.	M20_dimer domain-containing protein.	0.920
ARG1	ARG2	ENSCHIP00000025258	ENSCHIP00000017404	Arginase.	Arginase.	0.910
ARG1	ASL	ENSCHIP00000025258	ENSCHIP00000014908	Arginase.	Uncharacterized protein.	0.985
ARG1	CPS1	ENSCHIP00000025258	ENSCHIP00000030166	Arginase.	Carbamoyl-phosphate synthase 1.	0.731
ARG1	GLUD1	ENSCHIP00000025258	ENSCHIP00000000388	Arginase.	ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.407
ARG1	GLUL	ENSCHIP00000025258	ENSCHIP00000030828	Arginase.	Glutamine synthetase.	0.641
ARG1	GOT1	ENSCHIP00000025258	ENSCHIP00000029101	Arginase.	Aspartate aminotransferase.	0.444
ARG1	GOT2	ENSCHIP00000025258	ENSCHIP00000010968	Arginase.	Aspartate aminotransferase.	0.425
ARG1	NAGS	ENSCHIP00000025258	ENSCHIP00000003702	Arginase.	N-acetylglutamate synthase.	0.607
ARG1	NOS1	ENSCHIP00000025258	ENSCHIP00000031021	Arginase.	Nitric oxide synthase 1.	0.929
ARG1	NOS2	ENSCHIP00000025258	ENSCHIP00000026649	Arginase.	Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...]	0.986
ARG1	NOS3	ENSCHIP00000025258	ENSCHIP00000011023	Arginase.	Nitric oxide synthase; Produces nitric oxide (NO).	0.942
ARG1	OTC	ENSCHIP00000025258	ENSCHIP00000003494	Arginase.	Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	0.985
ARG2	ACY1	ENSCHIP00000017404	ENSCHIP00000015762	Arginase.	M20_dimer domain-containing protein.	0.920