STRINGSTRING
FMR1 FMR1 UPF3B UPF3B NXT2 NXT2 EIF4EBP2 EIF4EBP2 LOC108635911 LOC108635911 EIF3G EIF3G EIF2S3 EIF2S3 FXR2 FXR2 FUS FUS DDX39B DDX39B EIF3E EIF3E NUP205 NUP205 RPP25L RPP25L LOC108633285 LOC108633285 LOC106501919 LOC106501919 SEH1L SEH1L EIF4E1B EIF4E1B CASC3 CASC3 LOC108637516 LOC108637516 TRNT1 TRNT1 PABPC4L PABPC4L ENSCHIP00000003677 ENSCHIP00000003677 CYFIP2 CYFIP2 SUMO1 SUMO1 UPF3A UPF3A NUP62CL NUP62CL GEMIN8 GEMIN8 NUP58 NUP58 EIF4E EIF4E NUP42 NUP42 GEMIN2 GEMIN2 EIF4G1 EIF4G1 RPP25 RPP25 GEMIN7 GEMIN7 EIF3B EIF3B EEF1A1 EEF1A1 UPF1 UPF1 EIF2S1 EIF2S1 PAIP1 PAIP1 LOC102183049 LOC102183049 DDX20 DDX20 XPO5 XPO5 EIF3H EIF3H NUP62 NUP62 RBM8A RBM8A EIF3D EIF3D EIF4A2 EIF4A2 EIF4B EIF4B RPP38 RPP38 RANBP2 RANBP2 GEMIN6 GEMIN6 LOC102172503 LOC102172503 POP7 POP7 THOC6 THOC6 TGS1 TGS1 ELAC1 ELAC1 TPR TPR NUP37 NUP37 KPNB1 KPNB1 SEC13 SEC13 EIF2B1 EIF2B1 THOC1 THOC1 MAGOH MAGOH LOC102176643 LOC102176643 EIF2B3 EIF2B3 SUMO3 SUMO3 RPP21 RPP21 NMD3 NMD3 POP5 POP5 PNN PNN NUP98 NUP98 EEF1A2 EEF1A2 EIF3A EIF3A POP4 POP4 SAP18 SAP18 ENSCHIP00000016659 ENSCHIP00000016659 RPP40 RPP40 NDC1 NDC1 PRMT5 PRMT5 NUP155 NUP155 POP1 POP1 FXR1 FXR1 NUP188 NUP188 ALYREF ALYREF ACIN1 ACIN1 UBE2I UBE2I NUP85 NUP85 EIF4G2 EIF4G2 ENSCHIP00000018680 ENSCHIP00000018680 SNUPN SNUPN XPO1 XPO1 XPOT XPOT SENP2 SENP2 NUP210 NUP210 THOC7 THOC7 LOC108634721 LOC108634721 EIF4G3 EIF4G3 PABPC5 PABPC5 EIF4EBP1 EIF4EBP1 PHAX PHAX LOC102183400 LOC102183400 PABPC4 PABPC4 RPP14 RPP14 AAAS AAAS ENSCHIP00000021093 ENSCHIP00000021093 EIF1 EIF1 NCBP1 NCBP1 LOC108635156 LOC108635156 UPF2 UPF2 DDX19A DDX19A EIF3F EIF3F EIF2B2 EIF2B2 NUP43 NUP43 SRRM1-2 SRRM1-2 EIF5 EIF5 RAE1 RAE1 EIF1AX EIF1AX NUP160 NUP160 THOC3 THOC3 EIF3I EIF3I NUP93 NUP93 STRAP STRAP EIF4A1 EIF4A1 CLNS1A CLNS1A NUP210L NUP210L EIF1B EIF1B LOC102181259 LOC102181259 NUP35 NUP35 NUP88 NUP88 PABPC1 PABPC1 NUP153 NUP153 EIF4A3 EIF4A3 LOC102182187 LOC102182187 EIF2B4 EIF2B4 GLE1 GLE1 PABPC1L PABPC1L LOC102179815 LOC102179815 NUP50 NUP50 ELAC2 ELAC2 TARDBP TARDBP EIF2B5 EIF2B5 PYM1 PYM1 NUP214 NUP214 GEMIN5 GEMIN5 GEMIN4 GEMIN4 NUP133 NUP133 EIF2S2 EIF2S2 RANGAP1 RANGAP1 SUMO2 SUMO2 THOC5 THOC5 EIF4EBP3 EIF4EBP3 NUP107 NUP107 EIF5B EIF5B MAGOHB MAGOHB NUP54 NUP54
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FMR1Fragile X mental retardation 1. (632 aa)
UPF3BSmg4_UPF3 domain-containing protein. (483 aa)
NXT2Nuclear transport factor 2 like export factor 2. (197 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (120 aa)
LOC108635911GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
EIF3GEukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (320 aa)
EIF2S3Tr-type G domain-containing protein. (472 aa)
FXR2FMR1 autosomal homolog 2. (673 aa)
FUSFUS RNA binding protein. (522 aa)
DDX39BDExD-box helicase 39B. (428 aa)
EIF3EEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (445 aa)
NUP205Nucleoporin 205. (2003 aa)
RPP25LRibonuclease P/MRP subunit p25 like. (163 aa)
LOC108633285Uncharacterized protein. (200 aa)
LOC106501919DEAD-box helicase 19B. (479 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (422 aa)
EIF4E1BEukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (198 aa)
CASC3CASC3 exon junction complex subunit. (700 aa)
LOC108637516GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
TRNT1tRNA nucleotidyl transferase 1; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (436 aa)
PABPC4LPoly(A) binding protein cytoplasmic 4 like. (370 aa)
ENSCHIP00000003677Tr-type G domain-containing protein. (438 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
UPF3AUPF3A regulator of nonsense mediated mRNA decay. (503 aa)
NUP62CLNsp1_C domain-containing protein. (304 aa)
GEMIN8Gem nuclear organelle associated protein 8. (234 aa)
NUP58Nucleoporin 58. (586 aa)
EIF4EUncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
NUP42Nucleoporin 42. (420 aa)
GEMIN2Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (269 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1607 aa)
RPP25Ribonuclease P and MRP subunit p25. (199 aa)
GEMIN7Gem nuclear organelle associated protein 7. (128 aa)
EIF3BEukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (788 aa)
EEF1A1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
UPF1UPF1 RNA helicase and ATPase. (1126 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
PAIP1Poly(A) binding protein interacting protein 1. (400 aa)
LOC102183049Uncharacterized protein. (200 aa)
DDX20DEAD-box helicase 20. (825 aa)
XPO5Exportin 5. (1190 aa)
EIF3HEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (352 aa)
NUP62Nucleoporin 62. (523 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
EIF3DEukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (548 aa)
EIF4A2Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. (408 aa)
EIF4BRRM domain-containing protein. (615 aa)
RPP38Ribonuclease P/MRP subunit p38. (282 aa)
RANBP2RAN binding protein 2. (3077 aa)
GEMIN6Gem nuclear organelle associated protein 6. (166 aa)
LOC102172503Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (369 aa)
POP7Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences; Belongs to the histone-like Alba family. (140 aa)
THOC6THO complex 6. (341 aa)
TGS1Trimethylguanosine synthase 1. (853 aa)
ELAC1ElaC ribonuclease Z 1. (363 aa)
TPRTranslocated promoter region, nuclear basket protein. (2436 aa)
NUP37Nucleoporin 37. (326 aa)
KPNB1Karyopherin subunit beta 1. (877 aa)
SEC13WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (322 aa)
EIF2B1Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (305 aa)
THOC1THO complex 1. (657 aa)
MAGOHUncharacterized protein. (146 aa)
LOC102176643Tudor domain-containing protein. (295 aa)
EIF2B3Eukaryotic translation initiation factor 2B subunit gamma. (461 aa)
SUMO3Small ubiquitin-related modifier. (104 aa)
RPP21Ribonuclease P/MRP subunit p21. (154 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (503 aa)
POP5Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (170 aa)
PNNPinin, desmosome associated protein. (734 aa)
NUP98Nucleoporin 98. (1816 aa)
EEF1A2Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa)
EIF3AEukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (1368 aa)
POP4Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (220 aa)
SAP18Sin3A associated protein 18. (172 aa)
ENSCHIP00000016659Tr-type G domain-containing protein. (120 aa)
RPP40Ribonuclease P/MRP subunit p40. (362 aa)
NDC1NDC1 transmembrane nucleoporin. (823 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa)
NUP155Nucleoporin 155. (1391 aa)
POP1POP1 homolog, ribonuclease P/MRP subunit. (1016 aa)
FXR1FMR1 autosomal homolog 1. (648 aa)
NUP188Nucleoporin 188. (1751 aa)
ALYREFAly/REF export factor. (267 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1335 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa)
EIF4G2Eukaryotic translation initiation factor 4 gamma 2. (905 aa)
ENSCHIP00000018680Smg4_UPF3 domain-containing protein. (472 aa)
SNUPNSnurportin-1; Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs. Belongs to the snurportin family. (362 aa)
XPO1Exportin 1. (1071 aa)
XPOTExportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (962 aa)
SENP2ULP_PROTEASE domain-containing protein. (596 aa)
NUP210Nucleoporin 210. (1889 aa)
THOC7THO complex 7. (203 aa)
LOC108634721Tr-type G domain-containing protein. (473 aa)
EIF4G3Eukaryotic translation initiation factor 4 gamma 3. (1584 aa)
PABPC5Poly(A) binding protein cytoplasmic 5. (382 aa)
EIF4EBP1Uncharacterized protein. (118 aa)
PHAXPhosphorylated adaptor for RNA export. (394 aa)
LOC102183400Uncharacterized protein. (558 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
RPP14Ribonuclease P/MRP subunit p14. (124 aa)
AAASAladin WD repeat nucleoporin. (547 aa)
ENSCHIP00000021093RRM domain-containing protein. (290 aa)
EIF1Eukaryotic translation initiation factor 1. (113 aa)
NCBP1Nuclear cap binding protein subunit 1. (795 aa)
LOC108635156WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (274 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1272 aa)
DDX19ADEAD-box helicase 19A. (478 aa)
EIF3FEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (369 aa)
EIF2B2Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
NUP43Nucleoporin 43. (380 aa)
SRRM1-2PWI domain-containing protein. (141 aa)
EIF5W2 domain-containing protein. (430 aa)
RAE1Ribonucleic acid export 1. (368 aa)
EIF1AXEukaryotic translation initiation factor 1A X-linked; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (144 aa)
NUP160Nucleoporin 160. (1402 aa)
THOC3THO complex 3. (351 aa)
EIF3IEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (325 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (819 aa)
STRAPSerine/threonine kinase receptor associated protein. (350 aa)
EIF4A1Eukaryotic translation initiation factor 4A1; Belongs to the DEAD box helicase family. (406 aa)
CLNS1AChloride nucleotide-sensitive channel 1A. (237 aa)
NUP210LNucleoporin 210 like. (1860 aa)
EIF1BEukaryotic translation initiation factor 1B. (82 aa)
LOC102181259Uncharacterized protein. (1216 aa)
NUP35Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (310 aa)
NUP88Uncharacterized protein. (755 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
NUP153Nucleoporin 153. (1478 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
LOC102182187Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (912 aa)
EIF2B4Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (539 aa)
GLE1GLE1 RNA export mediator. (683 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (648 aa)
LOC102179815Uncharacterized protein. (1577 aa)
NUP50Nucleoporin 50. (465 aa)
ELAC2ElaC ribonuclease Z 2. (812 aa)
TARDBPTAR DNA binding protein. (414 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (724 aa)
PYM1PYM homolog 1, exon junction complex associated factor. (205 aa)
NUP214Nucleoporin 214. (2043 aa)
GEMIN5Gem nuclear organelle associated protein 5. (1508 aa)
GEMIN4Gem nuclear organelle associated protein 4. (1059 aa)
NUP133Nucleoporin 133. (1156 aa)
EIF2S2eIF2B_5 domain-containing protein. (340 aa)
RANGAP1Ran GTPase activating protein 1. (585 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
THOC5THO complex 5. (694 aa)
EIF4EBP3Eukaryotic translation initiation factor 4E binding protein 3. (102 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
EIF5BEukaryotic translation initiation factor 5B. (1220 aa)
MAGOHBUncharacterized protein. (148 aa)
NUP54Nucleoporin 54. (510 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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