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| | SNRPD3 | Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa) |
| | LOC108634523 | RRM domain-containing protein. (389 aa) |
| | PRPF18 | SFM domain-containing protein. (351 aa) |
| | PUF60 | Poly(U) binding splicing factor 60. (601 aa) |
| | FUS | FUS RNA binding protein. (522 aa) |
| | DDX39B | DExD-box helicase 39B. (428 aa) |
| | RBMXL2 | RRM domain-containing protein. (395 aa) |
| | SNRPD1 | Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa) |
| | SNRNP27-2 | SNRNP27 domain-containing protein. (152 aa) |
| | PCBP1 | Poly(rC) binding protein 1. (356 aa) |
| | SF3B5 | Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa) |
| | LOC102174442 | Uncharacterized protein. (284 aa) |
| | LOC102177976 | Uncharacterized protein. (320 aa) |
| | SNRPB2 | Small nuclear ribonucleoprotein polypeptide B2. (225 aa) |
| | DHX8 | DEAH-box helicase 8. (1216 aa) |
| | SNRNP40 | Small nuclear ribonucleoprotein U5 subunit 40. (358 aa) |
| | SRSF3 | RRM domain-containing protein. (124 aa) |
| | SF3B6 | Splicing factor 3b subunit 6. (125 aa) |
| | SNW1 | SNW domain containing 1. (536 aa) |
| | LSM6 | Sm domain-containing protein. (80 aa) |
| | HSPA2 | Heat shock-related 70 kDa protein 2; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis [...] (636 aa) |
| | SMNDC1 | Survival motor neuron domain containing 1. (238 aa) |
| | SRSF1 | Uncharacterized protein. (248 aa) |
| | LSM4 | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (151 aa) |
| | SF3B2 | Splicing factor 3b subunit 2. (895 aa) |
| | XAB2 | XPA binding protein 2. (892 aa) |
| | EFTUD2 | Elongation factor Tu GTP binding domain containing 2. (972 aa) |
| | RP9 | Uncharacterized protein. (221 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (622 aa) |
| | LOC102189034 | Uncharacterized protein. (320 aa) |
| | LOC102172949 | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa) |
| | RBM8A | RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa) |
| | SNRPG | Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa) |
| | PPIE | Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (292 aa) |
| | U2AF1 | Uncharacterized protein. (237 aa) |
| | CRNKL1 | Crooked neck pre-mRNA splicing factor 1. (693 aa) |
| | DHX16 | DEAH-box helicase 16. (1058 aa) |
| | CWC15 | CWC15 spliceosome associated protein homolog. (231 aa) |
| | RBMX | RRM domain-containing protein. (395 aa) |
| | SLU7 | SLU7 homolog, splicing factor. (586 aa) |
| | PPIL1 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa) |
| | PLRG1 | Pleiotropic regulator 1. (514 aa) |
| | LSM8 | U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (94 aa) |
| | DDX42 | DEAD-box helicase 42. (939 aa) |
| | CCDC12 | Coiled-coil domain containing 12. (168 aa) |
| | ZMAT2 | Zinc finger matrin-type 2. (199 aa) |
| | ENSCHIP00000013837 | Uncharacterized protein. (227 aa) |
| | SF3B1 | Splicing factor 3b subunit 1. (1304 aa) |
| | THOC1 | THO complex 1. (657 aa) |
| | BUD31 | BUD31 homolog. (144 aa) |
| | PRPF3 | Pre-mRNA processing factor 3. (683 aa) |
| | HNRNPA3 | Uncharacterized protein. (361 aa) |
| | MAGOH | Uncharacterized protein. (146 aa) |
| | RBM22 | RNA binding motif protein 22. (420 aa) |
| | SNRPD2 | Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (119 aa) |
| | SNU13 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (129 aa) |
| | SRSF6 | Uncharacterized protein. (345 aa) |
| | LSM2 | U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (94 aa) |
| | SNRPA1 | Small nuclear ribonucleoprotein polypeptide A. (255 aa) |
| | SART1 | Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (796 aa) |
| | SRSF5 | Serine and arginine rich splicing factor 5. (274 aa) |
| | SRSF2 | RRM domain-containing protein. (221 aa) |
| | HSPA8 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa) |
| | SNRPF | Sm domain-containing protein. (68 aa) |
| | ALYREF | Aly/REF export factor. (267 aa) |
| | PRPF8 | Pre-mRNA processing factor 8. (2335 aa) |
| | ACIN1 | Apoptotic chromatin condensation inducer 1. (1335 aa) |
| | CDC40 | Cell division cycle 40. (592 aa) |
| | PRPF6 | Pre-mRNA processing factor 6. (948 aa) |
| | SF3A2 | Splicing factor 3a subunit 2. (477 aa) |
| | PRPF19 | Pre-mRNA processing factor 19. (504 aa) |
| | SNRNP70 | RRM domain-containing protein. (166 aa) |
| | SF3A1 | Splicing factor 3a subunit 1. (808 aa) |
| | DDX23 | DEAD-box helicase 23. (820 aa) |
| | SRSF7 | Serine and arginine rich splicing factor 7. (238 aa) |
| | TXNL4A | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa) |
| | SF3B3 | Splicing factor 3b subunit 3. (1217 aa) |
| | LOC102174476 | G-patch domain-containing protein. (396 aa) |
| | NCBP1 | Nuclear cap binding protein subunit 1. (795 aa) |
| | SF3A3 | Splicing factor 3a subunit 3. (501 aa) |
| | SNRNP200 | Small nuclear ribonucleoprotein U5 subunit 200. (2146 aa) |
| | SYF2 | SYF2 pre-mRNA splicing factor. (243 aa) |
| | USP39 | Ubiquitin specific peptidase 39. (565 aa) |
| | PRPF31 | Pre-mRNA processing factor 31. (499 aa) |
| | THOC3 | THO complex 3. (351 aa) |
| | WBP11 | Uncharacterized protein. (640 aa) |
| | RBM25 | Uncharacterized protein. (187 aa) |
| | CDC5L | Cell division cycle 5 like. (802 aa) |
| | SRSF4 | Serine and arginine rich splicing factor 4. (517 aa) |
| | BCAS2 | Uncharacterized protein. (225 aa) |
| | PQBP1 | Polyglutamine binding protein 1. (263 aa) |
| | CTNNBL1 | Catenin beta like 1. (567 aa) |
| | HSPA1L | Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (642 aa) |
| | RBM17 | G-patch domain-containing protein. (401 aa) |
| | LSM7 | LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa) |
| | U2SURP | U2 snRNP associated SURP domain containing. (1029 aa) |
| | SRSF10-2 | RRM domain-containing protein. (69 aa) |
| | SNRPE | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa) |
| | PRPF40B | Pre-mRNA processing factor 40 homolog B. (865 aa) |
| | EIF4A3 | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa) |
| | PRPF38B | Uncharacterized protein. (543 aa) |
| | LSM5 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa) |
| | LSM3 | U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa) |
| | PRPF4 | WD_REPEATS_REGION domain-containing protein. (522 aa) |
| | PRPF38A | Pre-mRNA processing factor 38A. (312 aa) |
| | HNRNPA1 | Uncharacterized protein. (320 aa) |
| | SRSF9 | Serine and arginine rich splicing factor 9. (221 aa) |
| | ENSCHIP00000030780 | Uncharacterized protein. (371 aa) |
| | AQR | RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1471 aa) |
| | HSPA6 | Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (643 aa) |
| | SNRPB | Small nuclear ribonucleoprotein-associated protein. (231 aa) |
| | SF3B4 | Uncharacterized protein. (424 aa) |
| | LOC102179815 | Uncharacterized protein. (1577 aa) |
| | DDX46 | DEAD-box helicase 46. (1032 aa) |
| | DHX15 | DEAH-box helicase 15. (795 aa) |
| | SNRPA | Small nuclear ribonucleoprotein polypeptide A. (282 aa) |
| | DHX38 | DEAH-box helicase 38. (1227 aa) |
| | MAGOHB | Uncharacterized protein. (148 aa) |
