78 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACSL4	Acyl-CoA synthetase long chain family member 4. (711 aa)
	LOC102178903	Uncharacterized protein; Belongs to the cytochrome P450 family. (495 aa)
	SLC27A5	Solute carrier family 27 member 5. (690 aa)
	AQP7	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (330 aa)
	PCK1	Phosphoenolpyruvate carboxykinase 1. (622 aa)
	SCP2	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (546 aa)
	ACSL6	AMP-binding domain-containing protein. (722 aa)
	APOA5	Apolipoprotein A5. (368 aa)
	FABP4	Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	LOC102175985	ACB domain-containing protein. (87 aa)
	RXRB	Retinoid X receptor beta. (533 aa)
	PLIN4	Perilipin 4. (1328 aa)
	EHHADH	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase. (723 aa)
	MMP1	Matrix metallopeptidase 1. (475 aa)
	ACAA1	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
	GK2	Glycerol kinase 2; Belongs to the FGGY kinase family. (554 aa)
	UCP1	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (305 aa)
	ACSBG1	Acyl-CoA synthetase bubblegum family member 1. (765 aa)
	OLR1	Oxidized low density lipoprotein receptor 1. (272 aa)
	ACADL	Acyl-CoA dehydrogenase long chain. (430 aa)
	CYP7A1	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa)
	LOC102190925	Uncharacterized protein. (419 aa)
	LOC102181495	Uncharacterized protein; Belongs to the cytochrome P450 family. (519 aa)
	FABP6	Fatty acid binding protein 6. (128 aa)
	NR1H3	Uncharacterized protein. (447 aa)
	LOC100860959	Uncharacterized protein; Belongs to the CD36 family. (472 aa)
	PLIN2	Perilipin; Belongs to the perilipin family. (378 aa)
	PPARD	Peroxisome proliferator activated receptor delta. (441 aa)
	CPT2	Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (658 aa)
	FABP3	Heart-type fatty acid binding protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
	ACOX2	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (682 aa)
	ME3	Malic enzyme. (604 aa)
	APOC3	Apolipoprotein C3. (97 aa)
	HMGCS1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa)
	ACOX3	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa)
	DBI	Diazepam binding inhibitor, acyl-CoA binding protein. (87 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (557 aa)
	CPT1A	Carnitine O-palmitoyltransferase 1; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
	UBC	Ubiquitin C. (655 aa)
	FADS2	Fatty acid desaturase 2. (444 aa)
	LOC102184853	Uncharacterized protein; Belongs to the FGGY kinase family. (549 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
	ACSBG2	Acyl-CoA synthetase bubblegum family member 2. (672 aa)
	SLC27A2	Solute carrier family 27 member 2. (620 aa)
	ILK	Integrin linked kinase. (452 aa)
	SCD5	Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (337 aa)
	FABP1	Fatty acid binding protein. (127 aa)
	ACSL5	Acyl-CoA synthetase long chain family member 5. (683 aa)
	PLIN5	Perilipin; Belongs to the perilipin family. (456 aa)
	LOC108633303	Uncharacterized protein; Belongs to the CD36 family. (473 aa)
	PLTP	Phospholipid transfer protein. (496 aa)
	SCD	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (By similarity). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid ox [...] (359 aa)
	LOC108633198	Uncharacterized protein. (310 aa)
	APOA1	Uncharacterized protein. (265 aa)
	ACSL3	Acyl-CoA synthetase long chain family member 3. (720 aa)
	FABP2	FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	FABP5	FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
	ACSL1	Acyl-CoA synthetase long chain family member 1. (719 aa)
	ME1	Malic enzyme. (571 aa)
	ANGPTL4	Angiopoietin like 4. (413 aa)
	PLIN1	Perilipin; Belongs to the perilipin family. (516 aa)
	RXRA	NR LBD domain-containing protein. (106 aa)
	FABP7	Fatty acid binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	SLC27A6	Solute carrier family 27 member 6. (634 aa)
	APOA2	Apolipoprotein A2. (100 aa)
	PCK2	Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
	CYP27A1	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (537 aa)
	CD36	Uncharacterized protein; Belongs to the CD36 family. (472 aa)
	CYP8B1	Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (498 aa)
	CPT1C	Carnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (796 aa)
	HMGCS2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (487 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (470 aa)
	SLC27A4	Solute carrier family 27 member 4. (643 aa)
	ENSCHIP00000032705	Uncharacterized protein. (247 aa)
	ADIPOQ	C1q domain-containing protein. (283 aa)
	RXRG	Retinoid X receptor gamma. (539 aa)
	SLC27A1	Solute carrier family 27 member 1. (646 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAA1	ACADL	ENSCHIP00000006718	ENSCHIP00000009763	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA dehydrogenase long chain.	0.968
ACAA1	ACOX2	ENSCHIP00000006718	ENSCHIP00000012388	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.907
ACAA1	ACOX3	ENSCHIP00000006718	ENSCHIP00000013959	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.971
ACAA1	ACSBG1	ENSCHIP00000006718	ENSCHIP00000008229	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA synthetase bubblegum family member 1.	0.538
ACAA1	ACSBG2	ENSCHIP00000006718	ENSCHIP00000015812	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA synthetase bubblegum family member 2.	0.459
ACAA1	ACSL1	ENSCHIP00000006718	ENSCHIP00000026081	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA synthetase long chain family member 1.	0.770
ACAA1	ACSL3	ENSCHIP00000006718	ENSCHIP00000024361	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA synthetase long chain family member 3.	0.582
ACAA1	ACSL4	ENSCHIP00000006718	ENSCHIP00000000112	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA synthetase long chain family member 4.	0.552
ACAA1	ACSL5	ENSCHIP00000006718	ENSCHIP00000021425	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA synthetase long chain family member 5.	0.744
ACAA1	ACSL6	ENSCHIP00000006718	ENSCHIP00000003480	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	AMP-binding domain-containing protein.	0.720
ACAA1	CPT1A	ENSCHIP00000006718	ENSCHIP00000014243	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Carnitine O-palmitoyltransferase 1; Belongs to the carnitine/choline acetyltransferase family.	0.547
ACAA1	CPT2	ENSCHIP00000006718	ENSCHIP00000012047	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family.	0.771
ACAA1	DBI	ENSCHIP00000006718	ENSCHIP00000014154	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Diazepam binding inhibitor, acyl-CoA binding protein.	0.590
ACAA1	EHHADH	ENSCHIP00000006718	ENSCHIP00000006527	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase.	0.994
ACAA1	FABP1	ENSCHIP00000006718	ENSCHIP00000020981	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Fatty acid binding protein.	0.543
ACAA1	FABP4	ENSCHIP00000006718	ENSCHIP00000004118	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.541
ACAA1	FABP7	ENSCHIP00000006718	ENSCHIP00000028815	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Fatty acid binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.460
ACAA1	HMGCS1	ENSCHIP00000006718	ENSCHIP00000013847	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.986
ACAA1	HMGCS2	ENSCHIP00000006718	ENSCHIP00000031203	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.986
ACAA1	LOC102175985	ENSCHIP00000006718	ENSCHIP00000005048	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	ACB domain-containing protein.	0.483