(102 nodes) Oocyte meiosis network (Capra hircus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PPP3CB	Serine/threonine-protein phosphatase. (535 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
	CDK1	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (312 aa)
	ENSCHIP00000000726	Protein kinase domain-containing protein. (176 aa)
	MAPK14	Mitogen-activated protein kinase. (350 aa)
	LOC102174738	Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
	ANAPC2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (843 aa)
	PPP3R1	Uncharacterized protein. (170 aa)
	CALML4	Calmodulin like 4. (153 aa)
	LOC102188771	Zf-rbx1 domain-containing protein. (108 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (309 aa)
	FBXO43	F-box protein 43. (680 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2653 aa)
	ANAPC5	Anaphase promoting complex subunit 5. (747 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1188 aa)
	SPDYC	Speedy/RINGO cell cycle regulator family member C. (294 aa)
	CAMK2D	Protein kinase domain-containing protein. (532 aa)
	CALML5	Calmodulin like 5. (149 aa)
	CAMK2G	Calcium/calmodulin dependent protein kinase II gamma. (577 aa)
	CPEB4	Cytoplasmic polyadenylation element binding protein 4. (729 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
	SMC3	Structural maintenance of chromosomes protein. (1231 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1354 aa)
	MOS	MOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (340 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1172 aa)
	BUB1	BUB1 mitotic checkpoint serine/threonine kinase. (1090 aa)
	RPS6KA6	Non-specific serine/threonine protein kinase. (644 aa)
	YWHAQ	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (385 aa)
	CDC26	Cell division cycle 26. (85 aa)
	SGO1	Shugoshin 1. (577 aa)
	ANAPC11	RING-type domain-containing protein. (84 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	CCNB2	Cyclin B2; Belongs to the cyclin family. (398 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (522 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (314 aa)
	ESPL1	Extra spindle pole bodies like 1, separase. (2101 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (760 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
	FBXW11	F-box and WD repeat domain containing 11. (563 aa)
	YWHAH	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
	CCNB1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (427 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (760 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (360 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
	PPP2R5B	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (496 aa)
	CPEB3	Cytoplasmic polyadenylation element binding protein 3. (715 aa)
	SLK	STE20 like kinase. (1238 aa)
	PPP2R5A	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (492 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa)
	PPP2R5D	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (590 aa)
	IGF1	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa)
	LOC102175356	Uncharacterized protein. (227 aa)
	CDC27	Cell division cycle 27. (824 aa)
	PPP2R1B	Protein phosphatase 2 scaffold subunit Abeta. (615 aa)
	CDC20	WD_REPEATS_REGION domain-containing protein. (499 aa)
	ANAPC7	Anaphase promoting complex subunit 7. (598 aa)
	YWHAZ	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta polypeptide; Belongs to the 14-3-3 family. (245 aa)
	ANAPC13	Anaphase promoting complex subunit 13. (74 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1083 aa)
	CALM1	Calmodulin 2; Belongs to the calmodulin family. (149 aa)
	AR	Androgen receptor. (891 aa)
	ANAPC1	Anaphase promoting complex subunit 1. (1905 aa)
	PGR	Progesterone receptor. (912 aa)
	PPP2R5C	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa)
	RPS6KA3	Ribosomal protein S6 kinase. (740 aa)
	STAG3	Stromal antigen 3. (1240 aa)
	CPEB2	Cytoplasmic polyadenylation element binding protein 2. (1010 aa)
	CCNE2	Cyclin E2; Belongs to the cyclin family. (404 aa)
	PLK1	Serine/threonine-protein kinase PLK. (602 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1259 aa)
	YWHAE	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (243 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
	PPP2R1A	Protein phosphatase 2 scaffold subunit Aalpha. (598 aa)
	MAPK13	Mitogen-activated protein kinase. (366 aa)
	ANAPC4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (805 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	ANAPC10	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
	SPDYA	Speedy/RINGO cell cycle regulator family member A. (312 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1367 aa)
	CDC16	Cell division cycle 16. (620 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
	AURKA	Aurora kinase A; Belongs to the protein kinase superfamily. (405 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1134 aa)
	CCNE1	Cyclin E1; Belongs to the cyclin family. (411 aa)
	MAD2L1	Mitotic arrest deficient 2 like 1. (205 aa)
	CDC23	Cell division cycle 23. (597 aa)
	CAMK2A	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1230 aa)
	PPP2R5E	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
	YWHAG	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
	RBX1	RING-type domain-containing protein. (108 aa)
	PLCZ1	Phosphoinositide phospholipase C. (631 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1148 aa)
	CUL1	CULLIN_2 domain-containing protein; Belongs to the cullin family. (776 aa)
	CPEB1	Uncharacterized protein. (567 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (527 aa)
	FBXO5	F-box protein 5. (448 aa)
	PTTG1	Uncharacterized protein. (202 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSCHIP00000029495	ENSCHIP00000027672	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.595
ADCY1	ADCY3	ENSCHIP00000029495	ENSCHIP00000031539	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.946
ADCY1	ADCY4	ENSCHIP00000029495	ENSCHIP00000023057	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.578
ADCY1	ADCY5	ENSCHIP00000029495	ENSCHIP00000026715	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.562
ADCY1	ADCY6	ENSCHIP00000029495	ENSCHIP00000008741	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.569
ADCY1	ADCY7	ENSCHIP00000029495	ENSCHIP00000030493	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.733
ADCY1	ADCY8	ENSCHIP00000029495	ENSCHIP00000031940	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.956
ADCY1	ADCY9	ENSCHIP00000029495	ENSCHIP00000008390	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.699
ADCY1	ANAPC5	ENSCHIP00000029495	ENSCHIP00000004436	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Anaphase promoting complex subunit 5.	0.451
ADCY1	ANAPC7	ENSCHIP00000029495	ENSCHIP00000022015	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Anaphase promoting complex subunit 7.	0.451
ADCY1	CALM1	ENSCHIP00000029495	ENSCHIP00000024155	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 2; Belongs to the calmodulin family.	0.943
ADCY1	CALML4	ENSCHIP00000029495	ENSCHIP00000002266	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 4.	0.940
ADCY1	CALML5	ENSCHIP00000029495	ENSCHIP00000005970	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 5.	0.944
ADCY1	CAMK2A	ENSCHIP00000029495	ENSCHIP00000030301	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily.	0.725
ADCY1	CAMK2D	ENSCHIP00000029495	ENSCHIP00000005952	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase domain-containing protein.	0.729
ADCY1	CAMK2G	ENSCHIP00000029495	ENSCHIP00000006298	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II gamma.	0.667
ADCY1	PRKACA	ENSCHIP00000029495	ENSCHIP00000016231	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.945
ADCY1	PRKACB	ENSCHIP00000029495	ENSCHIP00000029151	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.944
ADCY2	ADCY1	ENSCHIP00000027672	ENSCHIP00000029495	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.595
ADCY2	ADCY3	ENSCHIP00000027672	ENSCHIP00000031539	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.461