STRINGSTRING
RAB7A RAB7A JUN JUN HRAS HRAS USP15 USP15 TAX1BP1 TAX1BP1 MAPK10 MAPK10 SP1 SP1 USP8 USP8 RPS27A RPS27A MAPK9 MAPK9 BCL2L13 BCL2L13 TFEB TFEB EIF2AK3 EIF2AK3 ATF4 ATF4 RELA RELA UBC UBC GABARAPL2 GABARAPL2 HIF1A HIF1A E2F1 E2F1 PARK2 PARK2 MFN2 MFN2 BNIP3 BNIP3 AMBRA1 AMBRA1 USP30 USP30 OPTN OPTN FOXO3 FOXO3 PGAM5 PGAM5 ULK1 ULK1 ATG5 ATG5 FUNDC1 FUNDC1 TBC1D17 TBC1D17 CSNK2A2 CSNK2A2 MFN1 MFN1 GABARAP GABARAP BECN1 BECN1 RRAS2 RRAS2 RAB7B RAB7B MITF MITF FIS1 FIS1 CSNK2A1 CSNK2A1 TBK1 TBK1 SQSTM1 SQSTM1 ATG9A ATG9A NRAS NRAS NBR1 NBR1 TOMM7 TOMM7 BCL2L1 BCL2L1 UBA52 UBA52 ATG9B ATG9B BNIP3L BNIP3L TP53 TP53 RRAS RRAS GABARAPL1 GABARAPL1 TFE3 TFE3 CALCOCO2 CALCOCO2 MAPK8 MAPK8 PINK1 PINK1 MRAS MRAS TBC1D15 TBC1D15 KRAS KRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAB7AUncharacterized protein. (207 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
TAX1BP1Tax1 binding protein 1. (827 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
SP1Uncharacterized protein. (786 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1085 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
BCL2L13BCL2 like 13. (425 aa)
TFEBTranscription factor EB. (478 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1114 aa)
ATF4Activating transcription factor 4. (352 aa)
RELARELA proto-oncogene, NF-kB subunit. (571 aa)
UBCUbiquitin C. (655 aa)
GABARAPL2Uncharacterized protein. (117 aa)
HIF1AUncharacterized protein. (823 aa)
E2F1E2F transcription factor 1. (441 aa)
PARK2Ubiquitin-like domain-containing protein. (293 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
BNIP3BCL2 interacting protein 3. (193 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1300 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa)
OPTNOptineurin. (573 aa)
FOXO3Forkhead box O3. (672 aa)
PGAM5PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (289 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1055 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
FUNDC1Uncharacterized protein. (155 aa)
TBC1D17TBC1 domain family member 17. (786 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (747 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
BECN1Uncharacterized protein. (448 aa)
RRAS2RAS related 2. (212 aa)
RAB7BRAB7B, member RAS oncogene family. (200 aa)
MITFMelanocyte inducing transcription factor. (519 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
TBK1TANK binding kinase 1. (734 aa)
SQSTM1Sequestosome 1. (440 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
NBR1NBR1 autophagy cargo receptor. (988 aa)
TOMM7Translocase of outer mitochondrial membrane 7. (55 aa)
BCL2L1BH4_2 domain-containing protein. (233 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (929 aa)
BNIP3LUncharacterized protein. (227 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
RRASRAS related. (218 aa)
GABARAPL1GABA type A receptor associated protein like 1. (117 aa)
TFE3Transcription factor binding to IGHM enhancer 3. (573 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (448 aa)
MAPK8Mitogen-activated protein kinase. (442 aa)
PINK1PTEN induced kinase 1. (587 aa)
MRASMuscle RAS oncogene homolog. (208 aa)
TBC1D15TBC1 domain family member 15. (691 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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