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| | PPP3CB | Serine/threonine-protein phosphatase. (535 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (589 aa) |
| | DAAM1 | Dishevelled associated activator of morphogenesis 1. (1082 aa) |
| | LOC102174738 | Uncharacterized protein; Belongs to the SKP1 family. (163 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa) |
| | PPP3R1 | Uncharacterized protein. (170 aa) |
| | LOC102188771 | Zf-rbx1 domain-containing protein. (108 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1186 aa) |
| | TBL1X | Uncharacterized protein. (528 aa) |
| | FRAT1 | Uncharacterized protein. (276 aa) |
| | FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | SFRP4 | Secreted frizzled related protein 4. (346 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa) |
| | LOC102180219 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (279 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (669 aa) |
| | FRAT2 | FRAT regulator of WNT signaling pathway 2. (229 aa) |
| | CAMK2D | Protein kinase domain-containing protein. (532 aa) |
| | CAMK2G | Calcium/calmodulin dependent protein kinase II gamma. (577 aa) |
| | AXIN1 | Axin 1. (867 aa) |
| | CXXC4 | CXXC finger protein 4. (373 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | TBL1XR1 | Transducin beta like 1 X-linked receptor 1. (520 aa) |
| | PRICKLE2 | Prickle planar cell polarity protein 2. (844 aa) |
| | TCF7L1 | Transcription factor 7 like 1. (587 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | ZNRF3 | Zinc and ring finger 3. (941 aa) |
| | VANGL1 | Vang-like protein. (537 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | WIF1 | WNT inhibitory factor 1. (379 aa) |
| | ENSCHIP00000009331 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (327 aa) |
| | CCN4 | Cellular communication network factor 4. (368 aa) |
| | FZD1 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (552 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (426 aa) |
| | PRICKLE1 | Prickle planar cell polarity protein 1. (834 aa) |
| | CSNK1A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (353 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (716 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa) |
| | CTNND2 | Catenin delta 2. (1164 aa) |
| | RSPO3 | R-spondin 3. (303 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | PPARD | Peroxisome proliferator activated receptor delta. (441 aa) |
| | RHOA | Ras-like protein family member A. (193 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (308 aa) |
| | PRICKLE3 | Prickle planar cell polarity protein 3. (619 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (416 aa) |
| | CBY1 | Uncharacterized protein. (127 aa) |
| | DAAM2 | Dishevelled associated activator of morphogenesis 2. (1087 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (522 aa) |
| | DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (262 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) |
| | BAMBI | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa) |
| | RSPO4 | R-spondin 4. (232 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (563 aa) |
| | VANGL2 | Vang-like protein. (522 aa) |
| | PORCN | Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (461 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (360 aa) |
| | LOC102183940 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa) |
| | CER1 | Cerberus 1, DAN family BMP antagonist. (263 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2305 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (714 aa) |
| | NOTUM | Notum, palmitoleoyl-protein carboxylesterase. (499 aa) |
| | CREBBP | CREB binding protein. (2435 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | SIAH1 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa) |
| | LGR5 | Leucine rich repeat containing G protein-coupled receptor 5. (907 aa) |
| | SENP2 | ULP_PROTEASE domain-containing protein. (596 aa) |
| | LOC108634926 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (336 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1615 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | SOST | Sclerostin. (212 aa) |
| | RSPO2 | R-spondin 2. (243 aa) |
| | AXIN2 | Axin 2. (844 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa) |
| | GPC4 | Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa) |
| | SOX17 | SRY-box transcription factor 17. (410 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (1002 aa) |
| | RAC3 | Rac family small GTPase 3. (192 aa) |
| | CACYBP | Calcyclin binding protein. (230 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | NKD1 | NKD inhibitor of WNT signaling pathway 1. (471 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) |
| | CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | NKD2 | NKD inhibitor of WNT signaling pathway 2. (483 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1073 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (416 aa) |
| | FOSL1 | FOS like 1, AP-1 transcription factor subunit. (271 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (294 aa) |
| | LOC102180576 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa) |
| | RYK | Receptor like tyrosine kinase. (609 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1219 aa) |
| | RSPO1 | Ovarian R-spondin member 1. (262 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (699 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (901 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa) |
| | PRKCA | Uncharacterized protein. (605 aa) |
| | APC | APC regulator of WNT signaling pathway. (2880 aa) |
| | SFRP5 | Secreted frizzled related protein 5. (320 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa) |
| | CTBP1 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (475 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | ROR2 | Receptor protein-tyrosine kinase. (926 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (442 aa) |
| | RBX1 | RING-type domain-containing protein. (108 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (736 aa) |
| | CUL1 | CULLIN_2 domain-containing protein; Belongs to the cullin family. (776 aa) |
| | DKK2 | Dickkopf WNT signaling pathway inhibitor 2. (259 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2583 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (555 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (579 aa) |
| | SERPINF1 | Serpin family F member 1; Belongs to the serpin family. (416 aa) |
| | MMP7 | Matrix metallopeptidase 7. (276 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (527 aa) |
| | FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (665 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | ROR1 | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (932 aa) |
| | TCF7 | Transcription factor 7. (418 aa) |
| | LGR4 | Leucine rich repeat containing G protein-coupled receptor 4. (951 aa) |
