61 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	YES1	Tyrosine-protein kinase. (541 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
	VCL	Vinculin. (1134 aa)
	LMO7	LIM domain 7. (1405 aa)
	CTNNA1	Catenin alpha 1. (1018 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	TCF7L2	Transcription factor 7 like 2. (669 aa)
	IQGAP1	IQ motif containing GTPase activating protein 1. (1657 aa)
	TCF7L1	Transcription factor 7 like 1. (587 aa)
	PTPRJ	Protein tyrosine phosphatase receptor type J. (1192 aa)
	ACTN4	Actinin alpha 4. (933 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
	WASF1	WASP family member 1. (570 aa)
	ACTB	Uncharacterized protein. (375 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	RHOA	Ras-like protein family member A. (193 aa)
	CDC42	Uncharacterized protein. (191 aa)
	INSR	Tyrosine-protein kinase receptor. (1365 aa)
	SNAI1	Snail family transcriptional repressor 1. (264 aa)
	PTPRF	Protein tyrosine phosphatase receptor type F. (1902 aa)
	PTPRM	Protein tyrosine phosphatase receptor type M. (1495 aa)
	ACTN1	Actinin alpha 1. (914 aa)
	CTNNA3	Uncharacterized protein. (530 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
	WASL	WASP like actin nucleation promoting factor. (505 aa)
	FER	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa)
	TJP1	Tight junction protein 1; Belongs to the MAGUK family. (1766 aa)
	BAIAP2	BAI1 associated protein 2. (535 aa)
	CREBBP	CREB binding protein. (2435 aa)
	WASF3	WASP family member 3. (501 aa)
	EP300	E1A binding protein p300. (2411 aa)
	CDH1	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (903 aa)
	PTPRB	Protein tyrosine phosphatase receptor type B. (2211 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (424 aa)
	NECTIN3	Nectin cell adhesion molecule 3. (549 aa)
	PARD3	Par-3 family cell polarity regulator. (1351 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	EGFR	Receptor protein-tyrosine kinase. (1208 aa)
	CSNK2A2	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
	RAC3	Rac family small GTPase 3. (192 aa)
	AFDN	Afadin, adherens junction formation factor. (1837 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
	CSNK2A1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
	NLK	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
	WASF2	WH2 domain-containing protein. (506 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1367 aa)
	WAS	WASP actin nucleation promoting factor. (536 aa)
	SNAI2	Snail family transcriptional repressor 2. (268 aa)
	CTNND1	Catenin delta 1. (939 aa)
	RAC2	Rac family small GTPase 2. (192 aa)
	MET	MET proto-oncogene, receptor tyrosine kinase. (1384 aa)
	NECTIN4	Nectin cell adhesion molecule 4. (509 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	SSX2IP	SSX family member 2 interacting protein. (611 aa)
	ERBB2	Receptor protein-tyrosine kinase. (1250 aa)
	NECTIN1	Nectin cell adhesion molecule 1. (515 aa)
	NECTIN2	Nectin cell adhesion molecule 2. (533 aa)
	CTNNA2	Uncharacterized protein. (394 aa)
	TCF7	Transcription factor 7. (418 aa)
	FARP2	FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1042 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ACTN1	ENSCHIP00000011080	ENSCHIP00000015198	Uncharacterized protein.	Actinin alpha 1.	0.968
ACTB	ACTN4	ENSCHIP00000011080	ENSCHIP00000007851	Uncharacterized protein.	Actinin alpha 4.	0.948
ACTB	AFDN	ENSCHIP00000011080	ENSCHIP00000025408	Uncharacterized protein.	Afadin, adherens junction formation factor.	0.929
ACTB	BAIAP2	ENSCHIP00000011080	ENSCHIP00000017374	Uncharacterized protein.	BAI1 associated protein 2.	0.936
ACTB	CDC42	ENSCHIP00000011080	ENSCHIP00000012064	Uncharacterized protein.	Uncharacterized protein.	0.979
ACTB	CDH1	ENSCHIP00000011080	ENSCHIP00000018788	Uncharacterized protein.	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.	0.720
ACTB	CREBBP	ENSCHIP00000011080	ENSCHIP00000018072	Uncharacterized protein.	CREB binding protein.	0.662
ACTB	CTNNA1	ENSCHIP00000011080	ENSCHIP00000002514	Uncharacterized protein.	Catenin alpha 1.	0.945
ACTB	CTNNA2	ENSCHIP00000011080	ENSCHIP00000033099	Uncharacterized protein.	Uncharacterized protein.	0.923
ACTB	CTNNA3	ENSCHIP00000011080	ENSCHIP00000015430	Uncharacterized protein.	Uncharacterized protein.	0.923
ACTB	CTNNB1	ENSCHIP00000011080	ENSCHIP00000031016	Uncharacterized protein.	Catenin beta 1.	0.906
ACTB	EGFR	ENSCHIP00000011080	ENSCHIP00000022759	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.891
ACTB	EP300	ENSCHIP00000011080	ENSCHIP00000018340	Uncharacterized protein.	E1A binding protein p300.	0.538
ACTB	ERBB2	ENSCHIP00000011080	ENSCHIP00000031717	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.755
ACTB	FYN	ENSCHIP00000011080	ENSCHIP00000004966	Uncharacterized protein.	Tyrosine-protein kinase.	0.714
ACTB	IGF1R	ENSCHIP00000011080	ENSCHIP00000028488	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.754
ACTB	INSR	ENSCHIP00000011080	ENSCHIP00000012457	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.568
ACTB	IQGAP1	ENSCHIP00000011080	ENSCHIP00000006181	Uncharacterized protein.	IQ motif containing GTPase activating protein 1.	0.961
ACTB	MAPK1	ENSCHIP00000011080	ENSCHIP00000000204	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.651
ACTB	MAPK3	ENSCHIP00000011080	ENSCHIP00000015503	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.403