STRINGSTRING
PPP3CB PPP3CB PRF1 PRF1 MAPK1 MAPK1 LOC102179822 LOC102179822 LOC102185735 LOC102185735 LOC108635363 LOC108635363 LOC102182286 LOC102182286 LOC108636744 LOC108636744 LOC108635529 LOC108635529 LOC108636634 LOC108636634 LOC108633243 LOC108633243 PAK1 PAK1 NCR1 NCR1 LOC108636739 LOC108636739 PPP3R1 PPP3R1 HRAS HRAS LOC108636750 LOC108636750 LOC102179943 LOC102179943 RAF1 RAF1 CD247 CD247 ENSCHIP00000003932 ENSCHIP00000003932 LOC102185698 LOC102185698 LOC108636544 LOC108636544 FYN FYN RAET1E RAET1E IFNA IFNA LOC102174842 LOC102174842 LOC102182573 LOC102182573 LOC108636627 LOC108636627 LOC108636629 LOC108636629 LOC102181867 LOC102181867 SHC3 SHC3 LOC102180761 LOC102180761 SH3BP2 SH3BP2 VAV1 VAV1 LOC102182856 LOC102182856 SH2D1B SH2D1B SYK SYK LOC108636632 LOC108636632 ZAP70 ZAP70 SH2D1A SH2D1A ITGAL ITGAL SHC1 SHC1 LOC102181595 LOC102181595 CASP3 CASP3 IFNGR1 IFNGR1 SHC4 SHC4 LCK LCK LOC108636773 LOC108636773 ITGB2 ITGB2 ENSCHIP00000012455 ENSCHIP00000012455 BID BID LOC102176878 LOC102176878 PPP3CC PPP3CC LOC108635630 LOC108635630 MAP2K2 MAP2K2 LOC108634246 LOC108634246 PIK3R3 PIK3R3 ICAM1 ICAM1 GRB2 GRB2 VAV3 VAV3 MAPK3 MAPK3 PIK3CA PIK3CA LOC102175759 LOC102175759 LOC102168343 LOC102168343 ENSCHIP00000015988 ENSCHIP00000015988 IFNG IFNG TNFSF10 TNFSF10 PRKCB PRKCB LOC106503874 LOC106503874 PLCG2 PLCG2 IFNGR2 IFNGR2 LOC102177285 LOC102177285 IFNAR1 IFNAR1 ENSCHIP00000019252 ENSCHIP00000019252 LOC102177708 LOC102177708 SOS1 SOS1 LOC108633160 LOC108633160 PTPN11 PTPN11 CD48 CD48 LOC102189064 LOC102189064 LOC108638310 LOC108638310 PIK3CB PIK3CB IFNAR2 IFNAR2 PTPN6 PTPN6 PIK3CD PIK3CD LOC102176598 LOC102176598 LOC108633178 LOC108633178 ENSCHIP00000023014 ENSCHIP00000023014 LOC102190602 LOC102190602 NFATC1 NFATC1 ENSCHIP00000023518 ENSCHIP00000023518 PIK3R1 PIK3R1 LOC108636749 LOC108636749 RAC3 RAC3 LOC102175959 LOC102175959 LOC102189305 LOC102189305 LOC102170874 LOC102170874 VAV2 VAV2 LOC108638467 LOC108638467 ENSCHIP00000025610 ENSCHIP00000025610 LOC108638461 LOC108638461 ARAF ARAF FASLG FASLG NRAS NRAS ULBP3 ULBP3 LOC108636742 LOC108636742 PRKCG PRKCG PRKCA PRKCA PLCG1 PLCG1 RAC2 RAC2 SOS2 SOS2 PTK2B PTK2B ENSCHIP00000032473 ENSCHIP00000032473 KRAS KRAS PPP3CA PPP3CA LOC102178567 LOC102178567 CSF2 CSF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP3CBSerine/threonine-protein phosphatase. (535 aa)
PRF1Perforin 1. (554 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
LOC102179822Ig-like domain-containing protein. (244 aa)
LOC102185735MHC_I-like_Ag-recog domain-containing protein. (258 aa)
LOC108635363Ig-like domain-containing protein. (298 aa)
LOC102182286C-type lectin domain-containing protein. (197 aa)
LOC108636744MHC_I-like_Ag-recog domain-containing protein. (208 aa)
LOC108635529Uncharacterized protein. (189 aa)
LOC108636634Uncharacterized protein. (186 aa)
LOC108633243Uncharacterized protein. (186 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
NCR1Ig-like domain-containing protein. (306 aa)
LOC108636739MHC_I-like_Ag-recog domain-containing protein. (283 aa)
PPP3R1Uncharacterized protein. (170 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
LOC108636750MHC_I-like_Ag-recog domain-containing protein. (264 aa)
LOC102179943Uncharacterized protein. (189 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
CD247CD247 molecule. (166 aa)
ENSCHIP00000003932MHC_I-like_Ag-recog domain-containing protein. (251 aa)
LOC102185698Uncharacterized protein. (250 aa)
LOC108636544Uncharacterized protein. (186 aa)
FYNTyrosine-protein kinase. (537 aa)
RAET1EMHC_I-like_Ag-recog domain-containing protein. (208 aa)
IFNAUncharacterized protein. (189 aa)
LOC102174842Uncharacterized protein. (189 aa)
LOC102182573C-type lectin domain-containing protein. (236 aa)
LOC108636627Uncharacterized protein. (189 aa)
LOC108636629Uncharacterized protein. (186 aa)
LOC102181867Uncharacterized protein. (186 aa)
SHC3SHC adaptor protein 3. (592 aa)
LOC102180761Uncharacterized protein. (189 aa)
SH3BP2SH3 domain binding protein 2. (551 aa)
VAV1Vav guanine nucleotide exchange factor 1. (844 aa)
LOC102182856C-type lectin domain-containing protein. (236 aa)
SH2D1BSH2 domain containing 1B. (133 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
LOC108636632Uncharacterized protein. (186 aa)
ZAP70Tyrosine-protein kinase. (622 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa)
ITGALVWFA domain-containing protein; Belongs to the integrin alpha chain family. (1178 aa)
SHC1SHC adaptor protein 1. (583 aa)
LOC102181595Uncharacterized protein. (186 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (275 aa)
IFNGR1Interferon gamma receptor 1. (500 aa)
SHC4SHC adaptor protein 4. (630 aa)
LCKTyrosine-protein kinase. (509 aa)
LOC108636773MHC_I-like_Ag-recog domain-containing protein. (247 aa)
ITGB2Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] (774 aa)
ENSCHIP00000012455TNFR-Cys domain-containing protein. (161 aa)
BIDUncharacterized protein. (244 aa)
LOC102176878Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (251 aa)
PPP3CCSerine/threonine-protein phosphatase. (522 aa)
LOC108635630Ig-like domain-containing protein. (216 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
LOC108634246Uncharacterized protein. (215 aa)
PIK3R3Uncharacterized protein. (461 aa)
ICAM1Intercellular adhesion molecule 1. (532 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC102175759Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (254 aa)
LOC102168343Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (256 aa)
ENSCHIP00000015988Uncharacterized protein. (157 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (287 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC106503874Ig-like domain-containing protein. (419 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
IFNGR2Interferon gamma receptor 2. (355 aa)
LOC102177285Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (560 aa)
ENSCHIP00000019252Uncharacterized protein. (252 aa)
LOC102177708MHC_I-like_Ag-recog domain-containing protein. (242 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1318 aa)
LOC108633160Uncharacterized protein. (189 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
CD48Ig-like domain-containing protein. (236 aa)
LOC102189064Uncharacterized protein. (369 aa)
LOC108638310ICAM_N domain-containing protein. (269 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
IFNAR2Uncharacterized protein. (534 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
LOC102176598Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (250 aa)
LOC108633178Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
ENSCHIP00000023014MHC_I-like_Ag-recog domain-containing protein. (277 aa)
LOC102190602Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (251 aa)
NFATC1Nuclear factor of activated T cells 1. (1002 aa)
ENSCHIP00000023518Uncharacterized protein. (167 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
LOC108636749MHC_I-like_Ag-recog domain-containing protein. (244 aa)
RAC3Rac family small GTPase 3. (192 aa)
LOC102175959Uncharacterized protein. (292 aa)
LOC102189305Ig-like domain-containing protein. (448 aa)
LOC102170874MHC_I-like_Ag-recog domain-containing protein. (310 aa)
VAV2Vav guanine nucleotide exchange factor 2. (872 aa)
LOC108638467Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (247 aa)
ENSCHIP00000025610TNFR-Cys domain-containing protein. (164 aa)
LOC108638461Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (251 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (611 aa)
FASLGFasL; Belongs to the tumor necrosis factor family. (277 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
ULBP3MHC_I-like_Ag-recog domain-containing protein. (245 aa)
LOC108636742MHC_I-like_Ag-recog domain-containing protein. (221 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (699 aa)
PRKCAUncharacterized protein. (605 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1296 aa)
RAC2Rac family small GTPase 2. (192 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
ENSCHIP00000032473Uncharacterized protein. (189 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PPP3CASerine/threonine-protein phosphatase. (527 aa)
LOC102178567ICAM_N domain-containing protein. (275 aa)
CSF2Granulocyte-macrophage colony stimulating factor. (144 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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