STRINGSTRING
PPP3CB PPP3CB MAPK1 MAPK1 DAPP1 DAPP1 JUN JUN PPP3R1 PPP3R1 HRAS HRAS RAF1 RAF1 NFKB1 NFKB1 RASGRP3 RASGRP3 CD81 CD81 NFKBIA NFKBIA VAV1 VAV1 BCL10 BCL10 SYK SYK CD79A CD79A IKBKB IKBKB GSK3B GSK3B PPP3CC PPP3CC MAP2K2 MAP2K2 INPPL1 INPPL1 RELA RELA AKT2 AKT2 PIK3R3 PIK3R3 GRB2 GRB2 VAV3 VAV3 MAPK3 MAPK3 PIK3CA PIK3CA MALT1 MALT1 PRKCB PRKCB CHUK CHUK PLCG2 PLCG2 INPP5D INPP5D SOS1 SOS1 PIK3CB PIK3CB PTPN6 PTPN6 PIK3CD PIK3CD PIK3AP1 PIK3AP1 NFATC1 NFATC1 CARD11 CARD11 PIK3R1 PIK3R1 BTK BTK RAC3 RAC3 VAV2 VAV2 CD22 CD22 LYN LYN NFATC3 NFATC3 NFKBIB NFKBIB NRAS NRAS AKT1 AKT1 IKBKG IKBKG CR2 CR2 RAC2 RAC2 AKT3 AKT3 FOS FOS SOS2 SOS2 CD72 CD72 KRAS KRAS PPP3CA PPP3CA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP3CBSerine/threonine-protein phosphatase. (535 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
DAPP1Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (280 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa)
PPP3R1Uncharacterized protein. (170 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
RASGRP3RAS guanyl releasing protein 3. (690 aa)
CD81Tetraspanin. (236 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
VAV1Vav guanine nucleotide exchange factor 1. (844 aa)
BCL10BCL10 immune signaling adaptor. (230 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
CD79ACD79a molecule. (223 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
PPP3CCSerine/threonine-protein phosphatase. (522 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
RELARELA proto-oncogene, NF-kB subunit. (571 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
PIK3R3Uncharacterized protein. (461 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MALT1MALT1 paracaspase. (830 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (740 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1202 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1318 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PIK3AP1Phosphoinositide-3-kinase adaptor protein 1. (781 aa)
NFATC1Nuclear factor of activated T cells 1. (1002 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
BTKTyrosine-protein kinase. (658 aa)
RAC3Rac family small GTPase 3. (192 aa)
VAV2Vav guanine nucleotide exchange factor 2. (872 aa)
CD22CD22 molecule. (843 aa)
LYNTyrosine-protein kinase. (512 aa)
NFATC3Nuclear factor of activated T cells 3. (1073 aa)
NFKBIBNFKB inhibitor beta. (364 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (495 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (408 aa)
CR2Uncharacterized protein. (1476 aa)
RAC2Rac family small GTPase 2. (192 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
CD72CD72 molecule. (361 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PPP3CASerine/threonine-protein phosphatase. (527 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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