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| | ND1 | NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (318 aa) |
| | ND2 | NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (347 aa) |
| | COX1 | Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (514 aa) |
| | COX2 | Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (227 aa) |
| | ATP8 | ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (65 aa) |
| | ATP6 | ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (226 aa) |
| | COX3 | Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa) |
| | ND3 | NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (115 aa) |
| | ND4L | NADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (98 aa) |
| | ND4 | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa) |
| | ND5 | NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (606 aa) |
| | ND6 | NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (175 aa) |
| | CYTB | Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa) |
| | LOC102186286 | Uncharacterized protein. (80 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (535 aa) |
| | NDUFA1 | NADH:ubiquinone oxidoreductase subunit A1. (70 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa) |
| | PPIF | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (208 aa) |
| | LOC102187765 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (498 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (350 aa) |
| | LOC102173355 | Uncharacterized protein. (51 aa) |
| | TUBA4A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (455 aa) |
| | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa) |
| | LOC108635646 | Uncharacterized protein. (64 aa) |
| | LOC102170877 | Uncharacterized protein. (63 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (537 aa) |
| | PPP3R1 | Uncharacterized protein. (170 aa) |
| | NDUFA13 | NADH:ubiquinone oxidoreductase subunit A13. (144 aa) |
| | PSMD13 | PCI domain-containing protein. (376 aa) |
| | CACNA1B | Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2358 aa) |
| | SLC25A5 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | LOC102168533 | Uncharacterized protein. (56 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2653 aa) |
| | NDUFS7 | NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (238 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (581 aa) |
| | SDHC | Succinate dehydrogenase complex subunit C. (169 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | NDUFA7 | Uncharacterized protein. (126 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | COX7B2 | Cytochrome c oxidase subunit 7B2. (78 aa) |
| | LOC102191741 | Uncharacterized protein. (152 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (442 aa) |
| | ATP5MC2 | ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (143 aa) |
| | HSPA2 | Heat shock-related 70 kDa protein 2; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis [...] (636 aa) |
| | KLC4 | Kinesin light chain 4. (616 aa) |
| | ATP5F1B | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa) |
| | STIP1 | Uncharacterized protein. (543 aa) |
| | C5 | Complement C5. (1675 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | NDUFA3 | Uncharacterized protein. (84 aa) |
| | C1QC | Complement C1q C chain. (244 aa) |
| | NDUFAB1 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa) |
| | NDUFB11 | Uncharacterized protein. (154 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (452 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | PSMA4 | Proteasome subunit alpha type. (284 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | SLC25A6 | Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | C8B | Complement C8 beta chain. (598 aa) |
| | KIF5C | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa) |
| | ATP5PB | ATP synthase peripheral stalk-membrane subunit b. (256 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (426 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | CYBB | Cytochrome b-245 beta chain. (570 aa) |
| | NCF4 | Neutrophil cytosolic factor 4. (339 aa) |
| | LOC102188434 | Uncharacterized protein. (169 aa) |
| | NCAM1 | Neural cell adhesion molecule 1. (1007 aa) |
| | CAV2 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa) |
| | VDAC2 | Voltage dependent anion channel 2. (294 aa) |
| | NDUFB7 | NADH:ubiquinone oxidoreductase subunit B7. (137 aa) |
| | CACNA1S | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1809 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (275 aa) |
| | LOC102183616 | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa) |
| | NDUFA6 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa) |
| | LOC102176290 | Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (91 aa) |
| | NDUFA9 | NADH:ubiquinone oxidoreductase subunit A9. (382 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | NDUFB4 | NADH:ubiquinone oxidoreductase subunit B4. (129 aa) |
| | PRNP | Major prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (256 aa) |
| | NDUFB8 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa) |
| | COX7A2L | Cytochrome c oxidase subunit 7A2 like. (114 aa) |
| | CYBA | Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (191 aa) |
| | LAMC1 | Laminin subunit gamma 1. (1608 aa) |
| | NDUFA10 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (355 aa) |
| | SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa) |
| | PSMA7 | Proteasome subunit alpha type. (248 aa) |
| | ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (560 aa) |
| | C9 | Complement C9. (548 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (522 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1114 aa) |
| | RYR1 | Ryanodine receptor 1. (5010 aa) |
| | ATF4 | Activating transcription factor 4. (352 aa) |
| | COX7A1 | Cytochrome c oxidase subunit 7A1. (80 aa) |
| | NDUFA4 | NADH dehydrogenase (Ubiquinone) 1 alpha subcomplex 4. (82 aa) |
| | NDUFS1 | NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (727 aa) |
| | UQCRC1 | Ubiquinol-cytochrome c reductase core protein 1. (480 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa) |
| | KIF5A | Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1063 aa) |
| | UQCRFS1 | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa) |
| | BAD | BCL2 associated agonist of cell death. (198 aa) |
| | KLC2 | Kinesin light chain 2. (622 aa) |
| | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2092 aa) |
| | ADRM1 | Adhesion regulating molecule 1. (407 aa) |
| | LOC102179296 | Uncharacterized protein. (333 aa) |
| | NDUFV2 | NADH:ubiquinone oxidoreductase core subunit V2. (249 aa) |
| | NDUFB1 | Uncharacterized protein. (58 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | LOC102188675 | Uncharacterized protein. (83 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | NDUFC1 | Uncharacterized protein. (76 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | C7 | Complement C7. (843 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (360 aa) |
| | NDUFS5 | NADH:ubiquinone oxidoreductase subunit S5. (106 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | UQCRC2 | Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | NCAM2 | Neural cell adhesion molecule 2. (860 aa) |
| | ATP5MC1 | ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (136 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | NDUFB2 | NADH:ubiquinone oxidoreductase subunit B2. (108 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (979 aa) |
| | HSPA8 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | PSMC6 | AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa) |
| | C1QB | Complement C1q B chain. (247 aa) |
| | LOC102183974 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (218 aa) |
| | UQCRQ | Ubiquinol-cytochrome c reductase complex III subunit VII. (82 aa) |
| | CYC1 | Cytochrome c1. (325 aa) |
| | NDUFS3 | NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (266 aa) |
| | GRIN2A | Glutamate ionotropic receptor NMDA type subunit 2A. (1402 aa) |
| | SLC25A31 | Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa) |
| | NDUFB10 | NADH:ubiquinone oxidoreductase subunit B10. (176 aa) |
| | SDHA | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa) |
| | ATP5MC3 | ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (141 aa) |
| | TUBA1B | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa) |
| | ATP5F1C | ATP synthase subunit gamma. (298 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (322 aa) |
| | PSMA8 | Proteasome subunit alpha type. (250 aa) |
| | LOC102173837 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (470 aa) |
| | KIF5B | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa) |
| | COX6A2 | Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa) |
| | COX6B2 | Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (88 aa) |
| | MCU | Mitochondrial calcium uniporter. (351 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | TUBAL3 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) |
| | LOC102178119 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2110 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | PSMA1 | Proteasome subunit alpha type. (263 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | TUBB4A | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa) |
| | PSMD9 | PDZ domain-containing protein. (221 aa) |
| | NDUFS6 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (124 aa) |
| | ATF6B | Activating transcription factor 6 beta. (708 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | SEM1 | Uncharacterized protein. (63 aa) |
| | NDUFB9 | NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (179 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | VDAC3 | Uncharacterized protein. (283 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | NDUFA11 | Uncharacterized protein. (141 aa) |
| | C6 | Complement C6. (932 aa) |
| | TUBB2B | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa) |
| | ATP5PF | ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa) |
| | TUBB4B | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) |
| | NCF1 | Neutrophil cytosolic factor 1. (392 aa) |
| | CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1497 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa) |
| | GRIN2C | Glutamate ionotropic receptor NMDA type subunit 2C. (1208 aa) |
| | NDUFV1 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa) |
| | NDUFB3 | NADH:ubiquinone oxidoreductase subunit B3. (98 aa) |
| | TUBA1A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (477 aa) |
| | HSPA1L | Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (642 aa) |
| | TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (493 aa) |
| | COX6B1 | Cytochrome c oxidase subunit 6B1. (99 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | NDUFA8 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (175 aa) |
| | ATP5F1E | Uncharacterized protein. (51 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | RYR3 | Ryanodine receptor 3. (4848 aa) |
| | COX8A | Cytochrome c oxidase subunit 8A. (69 aa) |
| | VDAC1 | Voltage dependent anion channel 1. (283 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (389 aa) |
| | NDUFS2 | NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (463 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | C1QA | Complement C1q A chain. (313 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | NDUFC2 | NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (120 aa) |
| | NDUFB5 | NADH:ubiquinone oxidoreductase subunit B5. (189 aa) |
| | HSPA5 | Heat shock 70kDa protein 5; Belongs to the heat shock protein 70 family. (655 aa) |
| | TUBA1C | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | TUBB6 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) |
| | NDUFS4 | NADH:ubiquinone oxidoreductase subunit S4. (175 aa) |
| | HSPA6 | Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (643 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (442 aa) |
| | TUBB2A | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa) |
| | TUBB | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (377 aa) |
| | TUBB1 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | LOC102173997 | Capra hircus breed Kapro cytochrome c mRNA; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | C8A | Complement C8 alpha chain. (585 aa) |
| | NDUFV3 | Uncharacterized protein. (109 aa) |
| | ATP5PD | ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (162 aa) |
| | LOC102172376 | Cytochrome c oxidase subunit 6A, mitochondrial. (111 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1249 aa) |
| | LOC106501717 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (465 aa) |
| | PSMD14 | MPN domain-containing protein. (310 aa) |
| | LOC102187154 | Uncharacterized protein. (64 aa) |
| | KLC3 | Kinesin light chain 3. (505 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (287 aa) |
| | GRIN3A | Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1116 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (527 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | SLC25A4 | Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | LOC102181148 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa) |
| | GRIN3B | Glutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1009 aa) |
| | RYR2 | Ryanodine receptor 2. (4943 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | NDUFA2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa) |
| | ATP5F1D | ATP synthase F1 subunit delta. (168 aa) |
| | GRIN2D | Glutamate ionotropic receptor NMDA type subunit 2D. (1334 aa) |
| | NDUFB6 | NADH:ubiquinone oxidoreductase subunit B6. (128 aa) |
