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| | PPP3CB | Serine/threonine-protein phosphatase. (535 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa) |
| | LAMP1 | Lysosomal associated membrane protein 1. (409 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (350 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (647 aa) |
| | RAB7A | Uncharacterized protein. (207 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa) |
| | LOC108635529 | Uncharacterized protein. (189 aa) |
| | LOC108636634 | Uncharacterized protein. (186 aa) |
| | LOC108633243 | Uncharacterized protein. (186 aa) |
| | JAK2 | Tyrosine-protein kinase. (1132 aa) |
| | HSPD1 | Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa) |
| | PPP3R1 | Uncharacterized protein. (170 aa) |
| | CALML4 | Calmodulin like 4. (153 aa) |
| | LOC102179943 | Uncharacterized protein. (189 aa) |
| | CTSD | Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (412 aa) |
| | ITGAX | VWFA domain-containing protein; Belongs to the integrin alpha chain family. (1180 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (648 aa) |
| | ATP6AP1 | ATPase H+ transporting accessory protein 1. (468 aa) |
| | MRC2 | Mannose receptor C type 2. (1488 aa) |
| | LOC102186320 | Uncharacterized protein. (479 aa) |
| | LOC102185698 | Uncharacterized protein. (250 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa) |
| | LOC108636544 | Uncharacterized protein. (186 aa) |
| | C3 | Complement C3. (1663 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | CEBPG | CCAAT enhancer binding protein gamma. (149 aa) |
| | IFNA | Uncharacterized protein. (189 aa) |
| | LOC102174842 | Uncharacterized protein. (189 aa) |
| | HLA-DMA | Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (278 aa) |
| | LOC102186442 | Ig-like domain-containing protein. (290 aa) |
| | STAT1 | Signal transducer and activator of transcription. (834 aa) |
| | CAMK2D | Protein kinase domain-containing protein. (532 aa) |
| | CALML5 | Calmodulin like 5. (149 aa) |
| | LOC108636627 | Uncharacterized protein. (189 aa) |
| | LOC108636629 | Uncharacterized protein. (186 aa) |
| | CAMK2G | Calcium/calmodulin dependent protein kinase II gamma. (577 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa) |
| | LOC102181867 | Uncharacterized protein. (186 aa) |
| | RAB5B | RAB5B, member RAS oncogene family. (216 aa) |
| | HLA-DOB | Major histocompatibility complex, class II, DO beta. (270 aa) |
| | MAP28 | Uncharacterized protein. (158 aa) |
| | PLA2R1 | Phospholipase A2 receptor 1. (1471 aa) |
| | MAP34-B | CAP18_C domain-containing protein. (165 aa) |
| | IL23A | Interleukin 23 subunit alpha. (190 aa) |
| | LOC102180761 | Uncharacterized protein. (189 aa) |
| | CD209 | C-type lectin domain-containing protein. (315 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (373 aa) |
| | BCL10 | BCL10 immune signaling adaptor. (230 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (452 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | LOC102171106 | Uncharacterized protein. (160 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (718 aa) |
| | SYK | Spleen associated tyrosine kinase. (636 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa) |
| | LOC108636632 | Uncharacterized protein. (186 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (426 aa) |
| | JAK1 | Tyrosine-protein kinase. (1159 aa) |
| | LAMP2 | Lysosomal associated membrane protein 2. (494 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (449 aa) |
| | IL10RA | Interleukin 10 receptor subunit alpha. (580 aa) |
| | RAB5C | Uncharacterized protein. (216 aa) |
| | LOC106503481 | Ig-like domain-containing protein. (274 aa) |
| | LOC102181595 | Uncharacterized protein. (186 aa) |
| | HLA-DRA | Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (253 aa) |
| | LOC102179937 | Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa) |
| | CLEC4E | C-type lectin domain family 4 member E. (212 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (275 aa) |
| | IFNGR1 | Interferon gamma receptor 1. (500 aa) |
| | RHOA | Ras-like protein family member A. (193 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | LSP1 | Uncharacterized protein. (362 aa) |
| | CD74 | CD74 molecule. (261 aa) |
| | ITGB2 | Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] (774 aa) |
| | ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa) |
| | ATP6V0A2 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (854 aa) |
| | HLA-DOA | Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (332 aa) |
| | BID | Uncharacterized protein. (244 aa) |
| | BAC7.5 | Uncharacterized protein. (190 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (522 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (571 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa) |
| | BAD | BCL2 associated agonist of cell death. (198 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (900 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (573 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | LOC102180664 | Ig-like domain-containing protein. (266 aa) |
| | BCL2 | BH4_2 domain-containing protein. (229 aa) |
| | ATP6V1H | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa) |
| | MALT1 | MALT1 paracaspase. (830 aa) |
| | IL10 | Interleukin 10. (177 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (331 aa) |
| | ATP6V0B | ATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (205 aa) |
| | ATP6V0D1 | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | IFNGR2 | Interferon gamma receptor 2. (355 aa) |
| | CREBBP | CREB binding protein. (2435 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | ENSCHIP00000019274 | Ig-like domain-containing protein. (253 aa) |
| | TLR4 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (841 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa) |
| | LOC108633160 | Uncharacterized protein. (189 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (488 aa) |
| | CIITA | Class II major histocompatibility complex transactivator. (1129 aa) |
| | LBP | Lipopolysaccharide binding protein. (481 aa) |
| | IL10RB | Interleukin 10 receptor subunit beta. (317 aa) |
| | HSPA9 | Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa) |
| | RFX5 | Regulatory factor X5. (615 aa) |
| | NFYA | Uncharacterized protein. (349 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | NFYC | Nuclear transcription factor Y subunit gamma. (335 aa) |
| | IRAK2 | Interleukin 1 receptor associated kinase 2. (622 aa) |
| | EEA1 | Early endosome antigen 1. (1452 aa) |
| | CALM1 | Calmodulin 2; Belongs to the calmodulin family. (149 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (461 aa) |
| | SPHK1 | Sphingosine kinase 1. (392 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (829 aa) |
| | LOC102186727 | Ig-like domain-containing protein; Belongs to the MHC class II family. (322 aa) |
| | ATP6V0D2 | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | CTSS | Cathepsin S; Belongs to the peptidase C1 family. (331 aa) |
| | LOC102169231 | Uncharacterized protein. (155 aa) |
| | NOS2 | Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1154 aa) |
| | ATP6V0C | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (495 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | VDR | Vitamin D receptor. (491 aa) |
| | BAC5 | Cathelicidin-2; Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Shows a potent antimicrobial activity against the Gram- negative bacteria E.coli, S.typhimurium and P.aeruginosa. Less active against the Gram-positive bacteria S.aureus, L.monocytogenes and B.subtilis; Belongs to the cathelicidin family. (176 aa) |
| | MRC1 | Mannose receptor C-type 1. (1455 aa) |
| | ATP6V0A1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (839 aa) |
| | SPHK2 | Sphingosine kinase 2. (653 aa) |
| | TLR9 | TIR domain-containing protein. (1070 aa) |
| | ATP6V0A4 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (834 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | NFYB | Nuclear transcription factor Y subunit beta. (205 aa) |
| | NOD2 | Uncharacterized protein. (982 aa) |
| | TRADD | TNFRSF1A associated via death domain. (312 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | RAB5A | Uncharacterized protein. (215 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (442 aa) |
| | LOC102173997 | Capra hircus breed Kapro cytochrome c mRNA; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | TLR2 | Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (794 aa) |
| | TIRAP | TIR domain containing adaptor protein. (228 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1249 aa) |
| | LOC106501717 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ENSCHIP00000032473 | Uncharacterized protein. (189 aa) |
| | LOC102187998 | Ig-like domain-containing protein. (262 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (527 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1543 aa) |
| | LOC102173987 | Uncharacterized protein. (349 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
