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| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa) |
| | OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa) |
| | CLDN9 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa) |
| | LOC108635529 | Uncharacterized protein. (189 aa) |
| | MX1 | MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (654 aa) |
| | LOC108636634 | Uncharacterized protein. (186 aa) |
| | LOC108633243 | Uncharacterized protein. (186 aa) |
| | CLDN6 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa) |
| | CLDN3 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa) |
| | CLDN20 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa) |
| | CLDN4 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa) |
| | RB1 | RB transcriptional corepressor 1. (931 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | LOC102186369 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | EIF3E | Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (445 aa) |
| | LOC102179943 | Uncharacterized protein. (189 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (161 aa) |
| | TRAF2 | TNF receptor-associated factor. (497 aa) |
| | EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4. (1649 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (648 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (466 aa) |
| | CLDN34 | Uncharacterized protein. (259 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | LOC108636544 | Uncharacterized protein. (186 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | LOC102186657 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | CLDN17 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa) |
| | IFNA | Uncharacterized protein. (189 aa) |
| | LOC102174842 | Uncharacterized protein. (189 aa) |
| | CD81 | Tetraspanin. (236 aa) |
| | STAT1 | Signal transducer and activator of transcription. (834 aa) |
| | LOC108636627 | Uncharacterized protein. (189 aa) |
| | LOC108636629 | Uncharacterized protein. (186 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | LOC102181867 | Uncharacterized protein. (186 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | E2F3 | E2F_TDP domain-containing protein. (460 aa) |
| | CLDN14 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (233 aa) |
| | LOC102180761 | Uncharacterized protein. (189 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | CLDN11 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (229 aa) |
| | IRF7 | Interferon regulatory factor 7. (480 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (452 aa) |
| | CLDN2 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (712 aa) |
| | LOC108636632 | Uncharacterized protein. (186 aa) |
| | YWHAQ | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa) |
| | JAK1 | Tyrosine-protein kinase. (1159 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (449 aa) |
| | LOC102181595 | Uncharacterized protein. (186 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (275 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | NR1H3 | Uncharacterized protein. (447 aa) |
| | PIAS1 | Protein inhibitor of activated STAT 1. (651 aa) |
| | MX2 | MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (713 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | EIF2AK1 | Eukaryotic translation initiation factor 2 alpha kinase 1. (619 aa) |
| | BID | Uncharacterized protein. (244 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1114 aa) |
| | MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa) |
| | CLDN10 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (571 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa) |
| | CXCL10 | C-X-C motif chemokine. (102 aa) |
| | BAD | BCL2 associated agonist of cell death. (198 aa) |
| | E2F1 | E2F transcription factor 1. (441 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (522 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (918 aa) |
| | IRF9 | Interferon regulatory factor 9. (470 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (573 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | STAT2 | Signal transducer and activator of transcription. (851 aa) |
| | YWHAH | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (543 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (470 aa) |
| | CFLAR | Uncharacterized protein; Belongs to the peptidase C14A family. (484 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (740 aa) |
| | CLDN19 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa) |
| | IRF3 | Interferon regulatory factor 3. (418 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (560 aa) |
| | SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa) |
| | TYK2 | Tyrosine-protein kinase. (1186 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1318 aa) |
| | LOC108633160 | Uncharacterized protein. (189 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (488 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | IFNAR2 | Uncharacterized protein. (534 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthetase 1. (390 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (615 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | YWHAZ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta polypeptide; Belongs to the 14-3-3 family. (245 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | CLDN16 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (254 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1208 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (786 aa) |
| | RNASEL | Ribonuclease L. (730 aa) |
| | IFIT1 | Interferon induced protein with tetratricopeptide repeats 1. (481 aa) |
| | RSAD2 | Radical S-adenosyl methionine domain containing 2. (364 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (611 aa) |
| | FASLG | FasL; Belongs to the tumor necrosis factor family. (277 aa) |
| | TBK1 | TANK binding kinase 1. (734 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | YWHAE | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (243 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (495 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (598 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (408 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | LOC102186893 | Uncharacterized protein. (709 aa) |
| | RXRA | NR LBD domain-containing protein. (106 aa) |
| | CLDN18 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa) |
| | TRADD | TNFRSF1A associated via death domain. (312 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | CLDN7 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | YWHAG | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | LOC102173997 | Capra hircus breed Kapro cytochrome c mRNA; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | DDX58 | DExD/H-box helicase 58. (942 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1249 aa) |
| | LOC106501717 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (470 aa) |
| | ENSCHIP00000032473 | Uncharacterized protein. (189 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (667 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | CLDN15 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa) |
| | CLDN8 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa) |
