Your Input: | |
| | RAB9A | RAB9A, member RAS oncogene family. (203 aa) |
| | LOC108635529 | Uncharacterized protein. (189 aa) |
| | MX1 | MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (654 aa) |
| | LOC108636634 | Uncharacterized protein. (186 aa) |
| | RAB9B | RAB9B, member RAS oncogene family. (201 aa) |
| | LOC108633243 | Uncharacterized protein. (186 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa) |
| | LOC102179943 | Uncharacterized protein. (189 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (378 aa) |
| | CD3D | CD3d molecule. (167 aa) |
| | EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4. (1649 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa) |
| | LOC108636544 | Uncharacterized protein. (186 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | IFNA | Uncharacterized protein. (189 aa) |
| | JAK3 | Tyrosine-protein kinase. (1138 aa) |
| | LOC102174842 | Uncharacterized protein. (189 aa) |
| | SLAMF1 | Ig-like domain-containing protein. (338 aa) |
| | IL2RA | Interleukin 2 receptor subunit alpha. (285 aa) |
| | STAT1 | Signal transducer and activator of transcription. (834 aa) |
| | RCHY1 | Ring finger and CHY zinc finger domain containing 1. (261 aa) |
| | LOC108636627 | Uncharacterized protein. (189 aa) |
| | LOC108636629 | Uncharacterized protein. (186 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | BBC3 | Uncharacterized protein. (193 aa) |
| | LOC102181867 | Uncharacterized protein. (186 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | HSPA2 | Heat shock-related 70 kDa protein 2; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis [...] (636 aa) |
| | LOC102180761 | Uncharacterized protein. (189 aa) |
| | CD209 | C-type lectin domain-containing protein. (315 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (640 aa) |
| | IRF7 | Interferon regulatory factor 7. (480 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | EIF3H | Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (352 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (452 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (712 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (718 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa) |
| | LOC108636632 | Uncharacterized protein. (186 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (426 aa) |
| | JAK1 | Tyrosine-protein kinase. (1159 aa) |
| | MSN | Moesin. (666 aa) |
| | LOC102181595 | Uncharacterized protein. (186 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (275 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | MX2 | MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (713 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | EIF2AK1 | Eukaryotic translation initiation factor 2 alpha kinase 1. (619 aa) |
| | BID | Uncharacterized protein. (244 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1114 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (571 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa) |
| | BAD | BCL2 associated agonist of cell death. (198 aa) |
| | RACK1 | Receptor for activated C kinase 1. (317 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (522 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | IRF9 | Interferon regulatory factor 9. (470 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (573 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | STAT2 | Signal transducer and activator of transcription. (851 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | BCL2 | BH4_2 domain-containing protein. (229 aa) |
| | EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (543 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | HSPA8 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (331 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (740 aa) |
| | ADAR | Adenosine deaminase RNA specific. (1175 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | IRF3 | Interferon regulatory factor 3. (418 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (560 aa) |
| | TLR4 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (841 aa) |
| | TYK2 | Tyrosine-protein kinase. (1186 aa) |
| | LOC108633160 | Uncharacterized protein. (189 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (488 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | IFIH1 | Interferon induced with helicase C domain 1. (1023 aa) |
| | IFNAR2 | Uncharacterized protein. (534 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthetase 1. (390 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa) |
| | TLR7 | TIR domain-containing protein. (1054 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (785 aa) |
| | STAT5B | Signal transducer and activator of transcription. (808 aa) |
| | STAT5A | Signal transducer and activator of transcription. (810 aa) |
| | CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | FASLG | FasL; Belongs to the tumor necrosis factor family. (277 aa) |
| | TBK1 | TANK binding kinase 1. (734 aa) |
| | NFKBIB | NFKB inhibitor beta. (364 aa) |
| | HSPA1L | Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (642 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (495 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (408 aa) |
| | LOC102186893 | Uncharacterized protein. (709 aa) |
| | BCL2L1 | BH4_2 domain-containing protein. (233 aa) |
| | TLR9 | TIR domain-containing protein. (1070 aa) |
| | CBLB | Cbl proto-oncogene B. (983 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | CD28 | CD28 molecule. (228 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (155 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (411 aa) |
| | TRADD | TNFRSF1A associated via death domain. (312 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | HSPA6 | Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (643 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (442 aa) |
| | LOC102173997 | Capra hircus breed Kapro cytochrome c mRNA; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | DDX58 | DExD/H-box helicase 58. (942 aa) |
| | TLR2 | Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (794 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1249 aa) |
| | LOC106501717 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ENSCHIP00000032473 | Uncharacterized protein. (189 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
