STRINGSTRING
PPP3CB PPP3CB MAPK1 MAPK1 GNG4 GNG4 MAPK14 MAPK14 LOC108635529 LOC108635529 LOC108636634 LOC108636634 LOC108633243 LOC108633243 LOC102179993 LOC102179993 LOC108638246 LOC108638246 LOC108633189 LOC108633189 RB1 RB1 PPP3R1 PPP3R1 HRAS HRAS CALML4 CALML4 PDGFRA PDGFRA LOC102179943 LOC102179943 CDKN1A CDKN1A TRAF2 TRAF2 CRKL CRKL RAF1 RAF1 LOC102189040 LOC102189040 E2F2 E2F2 PLCB2 PLCB2 LOC102172138 LOC102172138 FADD FADD LOC108636544 LOC108636544 NFKB1 NFKB1 ITPR3 ITPR3 CREB3L1 CREB3L1 B2M B2M IFNA IFNA CRK CRK VEGFA VEGFA LOC102174842 LOC102174842 LOC108633459 LOC108633459 ITGAV ITGAV GNAI2 GNAI2 CALML5 CALML5 LOC108636627 LOC108636627 ELK1 ELK1 TAPBP TAPBP LOC108636629 LOC108636629 NFKBIA NFKBIA STING1 STING1 LOC102181867 LOC102181867 GNG2 GNG2 CCND1 CCND1 GNB1 GNB1 E2F3 E2F3 PXN PXN LOC108633460 LOC108633460 LOC102180761 LOC102180761 CXCL12 CXCL12 GNB4 GNB4 GNAQ GNAQ ATF2 ATF2 ADCY9 ADCY9 CDK6 CDK6 CASP9 CASP9 ADCY6 ADCY6 LOC102188874 LOC102188874 GNA11 GNA11 IL6 IL6 LOC108636632 LOC108636632 LOC102169753 LOC102169753 JAK1 JAK1 SP1 SP1 TNFRSF1A TNFRSF1A IL10RA IL10RA IL1R1 IL1R1 LOC102181595 LOC102181595 ROCK2 ROCK2 CASP3 CASP3 MYC MYC CXCR4 CXCR4 RHOA RHOA PTK2 PTK2 GNA13 GNA13 IKBKB IKBKB BID BID AKAP13 AKAP13 GSK3B GSK3B LOC102179590 LOC102179590 PPP3CC PPP3CC ATF4 ATF4 MAP2K2 MAP2K2 RELA RELA AKT2 AKT2 GNG12 GNG12 GNG10 GNG10 E2F1 E2F1 PIK3R3 PIK3R3 GNG3 GNG3 CREB3L2 CREB3L2 GRB2 GRB2 MAPK3 MAPK3 PIK3CA PIK3CA GNG5 GNG5 ROCK1 ROCK1 BAK1 BAK1 BAX BAX PRKACA PRKACA CCL5 CCL5 ITPR2 ITPR2 TRAF5 TRAF5 LOC102171703 LOC102171703 PRKCB PRKCB LOC102181154 LOC102181154 CHUK CHUK TAP2 TAP2 GNAO1 GNAO1 ITGB3 ITGB3 IRF3 IRF3 PLCB1 PLCB1 LOC108633505 LOC108633505 TSC1 TSC1 CGAS CGAS ITPR1 ITPR1 ENSCHIP00000020123 ENSCHIP00000020123 SOS1 SOS1 GNG14 GNG14 EIF4EBP1 EIF4EBP1 LOC108633160 LOC108633160 CASP8 CASP8 GNGT1 GNGT1 LOC102176782 LOC102176782 LOC102181202 LOC102181202 PLCB3 PLCB3 PIK3CB PIK3CB IL10RB IL10RB MDM2 MDM2 MTOR MTOR CXCL8 CXCL8 PIK3CD PIK3CD STAT3 STAT3 ATF6B ATF6B PTGER3 PTGER3 CDK4 CDK4 EGFR EGFR LOC102181347 LOC102181347 ADCY4 ADCY4 CXCR2 CXCR2 NFATC1 NFATC1 PIK3R1 PIK3R1 RAC3 RAC3 LOC102170772 LOC102170772 CALM1 CALM1 ENSCHIP00000024897 ENSCHIP00000024897 TAP1 TAP1 ARHGEF1 ARHGEF1 GNG13 GNG13 GNGT2 GNGT2 NFATC3 NFATC3 FASLG FASLG TBK1 TBK1 ADCY5 ADCY5 NRAS NRAS AKT1 AKT1 PTGS2 PTGS2 GNAI1 GNAI1 CALR CALR ADCY2 ADCY2 IKBKG IKBKG CCL2 CCL2 MAPK13 MAPK13 PLCB4 PLCB4 PTGER4 PTGER4 PRKCG PRKCG PTGER1 PTGER1 NFATC4 NFATC4 CX3CL1 CX3CL1 GNA12 GNA12 LOC102185917 LOC102185917 LOC102168905 LOC102168905 PRKACB PRKACB PRKCA PRKCA GNB5 GNB5 IL1B IL1B GNAI3 GNAI3 ADCY1 ADCY1 LOC102188814 LOC102188814 PDIA3 PDIA3 GNG11 GNG11 RAC2 RAC2 TRADD TRADD TP53 TP53 ADCY7 ADCY7 AKT3 AKT3 GNG7 GNG7 CTNNB1 CTNNB1 SOS2 SOS2 ADCY3 ADCY3 LOC102173997 LOC102173997 ADCY8 ADCY8 LOC106501717 LOC106501717 CREB3L3 CREB3L3 PTK2B PTK2B BCAR1 BCAR1 ENSCHIP00000032473 ENSCHIP00000032473 LOC102180880 LOC102180880 RIPK1 RIPK1 KRAS KRAS PTGER2 PTGER2 PPP3CA PPP3CA ARHGEF12 ARHGEF12 CREB1 CREB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP3CBSerine/threonine-protein phosphatase. (535 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
MAPK14Mitogen-activated protein kinase. (350 aa)
LOC108635529Uncharacterized protein. (189 aa)
LOC108636634Uncharacterized protein. (186 aa)
LOC108633243Uncharacterized protein. (186 aa)
LOC102179993G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (355 aa)
LOC108638246C-C motif chemokine. (93 aa)
LOC108633189Uncharacterized protein. (241 aa)
RB1RB transcriptional corepressor 1. (931 aa)
PPP3R1Uncharacterized protein. (170 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
CALML4Calmodulin like 4. (153 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1108 aa)
LOC102179943Uncharacterized protein. (189 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (161 aa)
TRAF2TNF receptor-associated factor. (497 aa)
CRKLCRK like proto-oncogene, adaptor protein. (302 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
LOC102189040Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
E2F2E2F transcription factor 2. (437 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1186 aa)
LOC102172138Ig-like domain-containing protein; Belongs to the MHC class I family. (360 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa)
LOC108636544Uncharacterized protein. (186 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2653 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (581 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (124 aa)
IFNAUncharacterized protein. (189 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (214 aa)
LOC102174842Uncharacterized protein. (189 aa)
LOC108633459Ig-like domain-containing protein; Belongs to the MHC class I family. (369 aa)
ITGAVIntegrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1048 aa)
GNAI2G protein subunit alpha i2. (357 aa)
CALML5Calmodulin like 5. (149 aa)
LOC108636627Uncharacterized protein. (189 aa)
ELK1ETS transcription factor ELK1. (440 aa)
TAPBPTAP binding protein. (472 aa)
LOC108636629Uncharacterized protein. (186 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
STING1Transmembrane protein 173. (378 aa)
LOC102181867Uncharacterized protein. (186 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
GNB1WD_REPEATS_REGION domain-containing protein. (325 aa)
E2F3E2F_TDP domain-containing protein. (460 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (581 aa)
LOC108633460Ig-like domain-containing protein; Belongs to the MHC class I family. (383 aa)
LOC102180761Uncharacterized protein. (189 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (116 aa)
GNB4G protein subunit beta 4. (340 aa)
GNAQG protein subunit alpha q. (359 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1354 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (452 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1172 aa)
LOC102188874Uncharacterized protein. (394 aa)
GNA11G protein subunit alpha 11. (361 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa)
LOC108636632Uncharacterized protein. (186 aa)
LOC102169753Ig-like domain-containing protein; Belongs to the MHC class I family. (382 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
SP1Uncharacterized protein. (786 aa)
TNFRSF1ATNF receptor superfamily member 1A. (449 aa)
IL10RAInterleukin 10 receptor subunit alpha. (580 aa)
IL1R1Interleukin 1 receptor type 1. (573 aa)
LOC102181595Uncharacterized protein. (186 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (275 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
RHOARas-like protein family member A. (193 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1095 aa)
GNA13G protein subunit alpha 13. (377 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
BIDUncharacterized protein. (244 aa)
AKAP13A-kinase anchoring protein 13. (2818 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
LOC102179590C-C motif chemokine. (89 aa)
PPP3CCSerine/threonine-protein phosphatase. (522 aa)
ATF4Activating transcription factor 4. (352 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
RELARELA proto-oncogene, NF-kB subunit. (571 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
E2F1E2F transcription factor 1. (441 aa)
PIK3R3Uncharacterized protein. (461 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (360 aa)
CCL5C-C motif chemokine. (91 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
LOC102171703Ig-like domain-containing protein; Belongs to the MHC class I family. (382 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC102181154C-C motif chemokine. (93 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (740 aa)
TAP2Uncharacterized protein. (719 aa)
GNAO1G protein subunit alpha o1. (354 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (786 aa)
IRF3Interferon regulatory factor 3. (418 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
LOC108633505Ig-like domain-containing protein; Belongs to the MHC class I family. (324 aa)
TSC1Uncharacterized protein. (1158 aa)
CGASCyclic GMP-AMP synthase. (511 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa)
ENSCHIP00000020123Ig-like domain-containing protein; Belongs to the MHC class I family. (348 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1318 aa)
GNG14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
EIF4EBP1Uncharacterized protein. (118 aa)
LOC108633160Uncharacterized protein. (189 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (488 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
LOC102176782Ig-like domain-containing protein; Belongs to the MHC class I family. (357 aa)
LOC102181202Ig-like domain-containing protein; Belongs to the MHC class I family. (392 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
IL10RBInterleukin 10 receptor subunit beta. (317 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
ATF6BActivating transcription factor 6 beta. (708 aa)
PTGER3Prostaglandin E receptor 3. (400 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
EGFRReceptor protein-tyrosine kinase. (1208 aa)
LOC102181347Ig-like domain-containing protein; Belongs to the MHC class I family. (374 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1083 aa)
CXCR2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (359 aa)
NFATC1Nuclear factor of activated T cells 1. (1002 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
RAC3Rac family small GTPase 3. (192 aa)
LOC102170772C-C motif chemokine. (105 aa)
CALM1Calmodulin 2; Belongs to the calmodulin family. (149 aa)
ENSCHIP00000024897Ig-like domain-containing protein; Belongs to the MHC class I family. (361 aa)
TAP1Transporter 1, ATP binding cassette subfamily B member. (750 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (971 aa)
GNG13G protein subunit gamma 13. (67 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
NFATC3Nuclear factor of activated T cells 3. (1073 aa)
FASLGFasL; Belongs to the tumor necrosis factor family. (277 aa)
TBK1TANK binding kinase 1. (734 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1259 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (495 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
GNAI1G protein subunit alpha i1. (354 aa)
CALRCalreticulin. (417 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (408 aa)
CCL2C-C motif chemokine. (98 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1219 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (513 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (699 aa)
PTGER1Prostaglandin E receptor 1. (407 aa)
NFATC4Nuclear factor of activated T cells 4. (901 aa)
CX3CL1SCY domain-containing protein. (430 aa)
GNA12G protein subunit alpha 12. (382 aa)
LOC102185917Ig-like domain-containing protein; Belongs to the MHC class I family. (361 aa)
LOC102168905Ig-like domain-containing protein; Belongs to the MHC class I family. (375 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
PRKCAUncharacterized protein. (605 aa)
GNB5G protein subunit beta 5. (402 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa)
GNAI3G protein subunit alpha i3. (354 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1134 aa)
LOC102188814Ig-like domain-containing protein; Belongs to the MHC class I family. (360 aa)
PDIA3Protein disulfide-isomerase. (505 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
RAC2Rac family small GTPase 2. (192 aa)
TRADDTNFRSF1A associated via death domain. (312 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1230 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CTNNB1Catenin beta 1. (781 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1148 aa)
LOC102173997Capra hircus breed Kapro cytochrome c mRNA; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
LOC106501717Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (465 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (848 aa)
ENSCHIP00000032473Uncharacterized protein. (189 aa)
LOC102180880C-C motif chemokine. (92 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (667 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PTGER2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (348 aa)
PPP3CASerine/threonine-protein phosphatase. (527 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1543 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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