STRINGSTRING
PPP3CB PPP3CB MAPK1 MAPK1 CANX CANX LOC108635911 LOC108635911 TGFB3 TGFB3 POLB POLB JUN JUN RB1 RB1 ANAPC2 ANAPC2 PPP3R1 PPP3R1 HRAS HRAS CDKN1A CDKN1A TBPL1 TBPL1 IL2RG IL2RG PTEN PTEN CD3D CD3D LOC108637516 LOC108637516 TLN1 TLN1 SLC25A5 SLC25A5 E2F2 E2F2 LOC102172138 LOC102172138 NRP1 NRP1 TBP TBP TERT TERT NFKB1 NFKB1 ANAPC5 ANAPC5 CREB3L1 CREB3L1 B2M B2M JAK3 JAK3 IL2RA IL2RA HLA-DMA HLA-DMA LOC108633459 LOC108633459 LOC102186442 LOC102186442 ELK1 ELK1 NFKBIA NFKBIA DLG1 DLG1 CD4 CD4 CCND1 CCND1 HLA-DOB HLA-DOB E2F3 E2F3 LOC108633460 LOC108633460 ATF2 ATF2 TGFBR2 TGFBR2 ADCY9 ADCY9 XIAP XIAP ADCY6 ADCY6 TGFB1 TGFB1 SRF SRF SLC25A6 SLC25A6 IL6 IL6 TSPO TSPO MAPK10 MAPK10 TCF3 TCF3 ITGAL ITGAL IL15RA IL15RA RELB RELB LOC102169753 LOC102169753 JAK1 JAK1 TNFRSF1A TNFRSF1A IL1R1 IL1R1 LOC106503481 LOC106503481 CDC26 CDC26 HLA-DRA HLA-DRA LOC102179937 LOC102179937 VDAC2 VDAC2 MAP3K3 MAP3K3 MYC MYC SMAD3 SMAD3 LCK LCK CCNA1 CCNA1 ANAPC11 ANAPC11 MAPK9 MAPK9 MSX1 MSX1 ITGB2 ITGB2 IKBKB IKBKB VAC14 VAC14 HLA-DOA HLA-DOA CCNB2 CCNB2 PPP3CC PPP3CC LTA LTA ATF4 ATF4 MAP2K2 MAP2K2 RELA RELA AKT2 AKT2 ESPL1 ESPL1 ETS2 ETS2 KAT5 KAT5 SLC2A1 SLC2A1 E2F1 E2F1 PIK3R3 PIK3R3 ETS1 ETS1 ICAM1 ICAM1 CREB3L2 CREB3L2 BUB1B BUB1B MAPK3 MAPK3 PIK3CA PIK3CA LOC102180664 LOC102180664 BAX BAX PRKACA PRKACA ATM ATM LOC102171703 LOC102171703 CHUK CHUK MAP3K14 MAP3K14 CREBBP CREBBP CCNA2 CCNA2 EP300 EP300 SLC25A31 SLC25A31 XPO1 XPO1 LOC108633505 LOC108633505 ENSCHIP00000019274 ENSCHIP00000019274 CDKN2C CDKN2C CRTC3 CRTC3 EGR2 EGR2 ENSCHIP00000020123 ENSCHIP00000020123 ELK4 ELK4 LOC102176782 LOC102176782 LOC102181202 LOC102181202 PIK3CB PIK3CB SPI1 SPI1 CDC27 CDC27 NFKB2 NFKB2 CDC20 CDC20 ANAPC7 ANAPC7 FDPS FDPS SMAD2 SMAD2 PIK3CD PIK3CD ATF6B ATF6B CRTC1 CRTC1 CDK4 CDK4 LOC102181347 LOC102181347 ADCY4 ADCY4 VDAC3 VDAC3 MSX2-2 MSX2-2 NFATC1 NFATC1 RANBP3 RANBP3 BUB3 BUB3 KAT2A KAT2A PIK3R1 PIK3R1 TLN2 TLN2 ANAPC1 ANAPC1 STAT5B STAT5B ENSCHIP00000024897 ENSCHIP00000024897 ATR ATR LOC102186727 LOC102186727 STAT5A STAT5A TGFBR1 TGFBR1 TGFB2 TGFB2 EGR1 EGR1 NFATC3 NFATC3 CCNE2 CCNE2 KAT2B KAT2B FOSL1 FOSL1 RANBP1 RANBP1 ADCY5 ADCY5 LTBR LTBR NRAS NRAS CRTC2 CRTC2 ZFP36 ZFP36 AKT1 AKT1 MSX2 MSX2 CALR CALR ADCY2 ADCY2 IKBKG IKBKG CHEK2 CHEK2 ANAPC4 ANAPC4 ANAPC10 ANAPC10 IL1R2 IL1R2 NFATC4 NFATC4 BCL2L1 BCL2L1 VDAC1 VDAC1 LOC102185917 LOC102185917 CD40 CD40 CDC16 CDC16 LOC102168905 LOC102168905 PRKACB PRKACB IL15 IL15 ADCY1 ADCY1 LOC102188814 LOC102188814 IL2 IL2 CCNE1 CCNE1 NFYB NFYB TP53 TP53 MAD2L1 MAD2L1 CDC23 CDC23 CCND2 CCND2 ADCY7 ADCY7 AKT3 AKT3 TRRAP TRRAP CHEK1 CHEK1 FOS FOS MAPK8 MAPK8 MAP2K4 MAP2K4 CDKN2B CDKN2B ADCY3 ADCY3 ADCY8 ADCY8 CREB3L3 CREB3L3 MAP3K1 MAP3K1 MMP7 MMP7 LOC102187998 LOC102187998 KRAS KRAS PPP3CA PPP3CA SLC25A4 SLC25A4 TBPL2 TBPL2 CCND3 CCND3 PTTG1 PTTG1 CREB1 CREB1 CSF2 CSF2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP3CBSerine/threonine-protein phosphatase. (535 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
CANXCalnexin. (593 aa)
LOC108635911GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa)
RB1RB transcriptional corepressor 1. (931 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (843 aa)
PPP3R1Uncharacterized protein. (170 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (161 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
IL2RGFibronectin type-III domain-containing protein. (378 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
CD3DCD3d molecule. (167 aa)
LOC108637516GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
TLN1Talin 1. (2558 aa)
SLC25A5Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
E2F2E2F transcription factor 2. (437 aa)
LOC102172138Ig-like domain-containing protein; Belongs to the MHC class I family. (360 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
TBPUncharacterized protein. (327 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1123 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
ANAPC5Anaphase promoting complex subunit 5. (747 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (581 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (124 aa)
JAK3Tyrosine-protein kinase. (1138 aa)
IL2RAInterleukin 2 receptor subunit alpha. (285 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (278 aa)
LOC108633459Ig-like domain-containing protein; Belongs to the MHC class I family. (369 aa)
LOC102186442Ig-like domain-containing protein. (290 aa)
ELK1ETS transcription factor ELK1. (440 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
CD4CD4 molecule. (455 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (270 aa)
E2F3E2F_TDP domain-containing protein. (460 aa)
LOC108633460Ig-like domain-containing protein; Belongs to the MHC class I family. (383 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1354 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1172 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SRFSerum response factor. (509 aa)
SLC25A6Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa)
TSPOTranslocator protein. (169 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
TCF3Transcription factor 3. (642 aa)
ITGALVWFA domain-containing protein; Belongs to the integrin alpha chain family. (1178 aa)
IL15RASushi domain-containing protein. (277 aa)
RELBRELB proto-oncogene, NF-kB subunit. (645 aa)
LOC102169753Ig-like domain-containing protein; Belongs to the MHC class I family. (382 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
TNFRSF1ATNF receptor superfamily member 1A. (449 aa)
IL1R1Interleukin 1 receptor type 1. (573 aa)
LOC106503481Ig-like domain-containing protein. (274 aa)
CDC26Cell division cycle 26. (85 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (253 aa)
LOC102179937Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
VDAC2Voltage dependent anion channel 2. (294 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (620 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
LCKTyrosine-protein kinase. (509 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (421 aa)
ANAPC11RING-type domain-containing protein. (84 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MSX1Msh homeobox 1. (303 aa)
ITGB2Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] (774 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
VAC14VAC14 component of PIKFYVE complex. (783 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (332 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (398 aa)
PPP3CCSerine/threonine-protein phosphatase. (522 aa)
LTALymphotoxin alpha; Belongs to the tumor necrosis factor family. (205 aa)
ATF4Activating transcription factor 4. (352 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
RELARELA proto-oncogene, NF-kB subunit. (571 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2101 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (470 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
SLC2A1MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (500 aa)
E2F1E2F transcription factor 1. (441 aa)
PIK3R3Uncharacterized protein. (461 aa)
ETS1Uncharacterized protein. (485 aa)
ICAM1Intercellular adhesion molecule 1. (532 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
BUB1BUncharacterized protein. (1062 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC102180664Ig-like domain-containing protein. (266 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (360 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa)
LOC102171703Ig-like domain-containing protein; Belongs to the MHC class I family. (382 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (740 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (953 aa)
CREBBPCREB binding protein. (2435 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (430 aa)
EP300E1A binding protein p300. (2411 aa)
SLC25A31Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa)
XPO1Exportin 1. (1071 aa)
LOC108633505Ig-like domain-containing protein; Belongs to the MHC class I family. (324 aa)
ENSCHIP00000019274Ig-like domain-containing protein. (253 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
CRTC3CREB regulated transcription coactivator 3. (619 aa)
EGR2Early growth response 2. (472 aa)
ENSCHIP00000020123Ig-like domain-containing protein; Belongs to the MHC class I family. (348 aa)
ELK4ETS transcription factor ELK4. (432 aa)
LOC102176782Ig-like domain-containing protein; Belongs to the MHC class I family. (357 aa)
LOC102181202Ig-like domain-containing protein; Belongs to the MHC class I family. (392 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
SPI1Spi-1 proto-oncogene. (270 aa)
CDC27Cell division cycle 27. (824 aa)
NFKB2Nuclear factor kappa B subunit 2. (900 aa)
CDC20WD_REPEATS_REGION domain-containing protein. (499 aa)
ANAPC7Anaphase promoting complex subunit 7. (598 aa)
FDPSFarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (353 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
ATF6BActivating transcription factor 6 beta. (708 aa)
CRTC1CREB regulated transcription coactivator 1. (629 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
LOC102181347Ig-like domain-containing protein; Belongs to the MHC class I family. (374 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1083 aa)
VDAC3Uncharacterized protein. (283 aa)
MSX2-2Uncharacterized protein. (154 aa)
NFATC1Nuclear factor of activated T cells 1. (1002 aa)
RANBP3RAN binding protein 3. (557 aa)
BUB3BUB3 mitotic checkpoint protein. (328 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
TLN2Talin 2. (2542 aa)
ANAPC1Anaphase promoting complex subunit 1. (1905 aa)
STAT5BSignal transducer and activator of transcription. (808 aa)
ENSCHIP00000024897Ig-like domain-containing protein; Belongs to the MHC class I family. (361 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
LOC102186727Ig-like domain-containing protein; Belongs to the MHC class II family. (322 aa)
STAT5ASignal transducer and activator of transcription. (810 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
NFATC3Nuclear factor of activated T cells 3. (1073 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (810 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
RANBP1RAN binding protein 1. (206 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1259 aa)
LTBRUncharacterized protein. (428 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
CRTC2CREB regulated transcription coactivator 2. (706 aa)
ZFP36ZFP36 ring finger protein. (325 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (495 aa)
MSX2Homeobox domain-containing protein. (267 aa)
CALRCalreticulin. (417 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (408 aa)
CHEK2Checkpoint kinase 2. (534 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (805 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
IL1R2Interleukin 1 receptor type 2. (400 aa)
NFATC4Nuclear factor of activated T cells 4. (901 aa)
BCL2L1BH4_2 domain-containing protein. (233 aa)
VDAC1Voltage dependent anion channel 1. (283 aa)
LOC102185917Ig-like domain-containing protein; Belongs to the MHC class I family. (361 aa)
CD40CD40 molecule. (280 aa)
CDC16Cell division cycle 16. (620 aa)
LOC102168905Ig-like domain-containing protein; Belongs to the MHC class I family. (375 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (161 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1134 aa)
LOC102188814Ig-like domain-containing protein; Belongs to the MHC class I family. (360 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (155 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (411 aa)
NFYBNuclear transcription factor Y subunit beta. (205 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
CDC23Cell division cycle 23. (597 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1230 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3881 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
MAPK8Mitogen-activated protein kinase. (442 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (412 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (138 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1148 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (465 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1507 aa)
MMP7Matrix metallopeptidase 7. (276 aa)
LOC102187998Ig-like domain-containing protein. (262 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PPP3CASerine/threonine-protein phosphatase. (527 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
TBPL2TATA-box binding protein like 2. (357 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
PTTG1Uncharacterized protein. (202 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CSF2Granulocyte-macrophage colony stimulating factor. (144 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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