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| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa) |
| | ANK3 | Ankyrin 3. (2586 aa) |
| | PLAU | Plasminogen activator, urokinase. (440 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (350 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (589 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (544 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | NUDT16L1 | Nudix hydrolase 16 like 1. (211 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (161 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1390 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (648 aa) |
| | HPSE2 | Heparanase 2 (inactive). (324 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | PPP1R12A | Protein phosphatase 1 regulatory subunit. (1029 aa) |
| | ANK1 | Ankyrin 1. (1866 aa) |
| | TWIST2 | Twist family bHLH transcription factor 2. (160 aa) |
| | CBL | Cbl proto-oncogene. (932 aa) |
| | FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2653 aa) |
| | CTSV | Uncharacterized protein; Belongs to the peptidase C1 family. (334 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa) |
| | HPSE | Heparanase. (545 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (214 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa) |
| | HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (814 aa) |
| | ITGAV | Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1048 aa) |
| | CAMK2D | Protein kinase domain-containing protein. (532 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) |
| | ELK1 | ETS transcription factor ELK1. (440 aa) |
| | IQGAP1 | IQ motif containing GTPase activating protein 1. (1657 aa) |
| | CAMK2G | Calcium/calmodulin dependent protein kinase II gamma. (577 aa) |
| | RPS6 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (255 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | PXN | Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (581 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (508 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (801 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (844 aa) |
| | FLNA | Filamin A. (2647 aa) |
| | HOXD10 | Homeobox D10. (340 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (622 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | NANOG | Homeobox domain-containing protein. (300 aa) |
| | EIF4B | RRM domain-containing protein. (615 aa) |
| | FZD1 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (552 aa) |
| | PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (385 aa) |
| | MSN | Moesin. (666 aa) |
| | CAV2 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa) |
| | PPP1R12B | Protein phosphatase 1 regulatory subunit. (983 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa) |
| | ACTB | Uncharacterized protein. (375 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (275 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | PTCH1 | Patched 1. (1453 aa) |
| | RHOA | Ras-like protein family member A. (193 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa) |
| | CDC42 | Uncharacterized protein. (191 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1344 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1095 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (596 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | TFAP4 | Transcription factor AP-4. (335 aa) |
| | VTN | SMB domain-containing protein. (475 aa) |
| | ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1100 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (416 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (314 aa) |
| | HSPG2 | Heparan sulfate proteoglycan 2. (4353 aa) |
| | MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (557 aa) |
| | SDC2 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (202 aa) |
| | HIF1A | Uncharacterized protein. (823 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | FLNB | Filamin B. (2602 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (875 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa) |
| | MMP2 | Matrix metallopeptidase 2. (661 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa) |
| | ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (802 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (360 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa) |
| | MMP9 | Uncharacterized protein. (709 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (331 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (714 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa) |
| | PPP1R12C | Protein phosphatase 1 regulatory subunit. (782 aa) |
| | THBS1 | Thrombospondin 1. (1218 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (786 aa) |
| | EZR | Ezrin. (581 aa) |
| | TIAM1 | T cell lymphoma invasion and metastasis 1. (1591 aa) |
| | DCN | Decorin; May affect the rate of fibrils formation. (360 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa) |
| | ANK2 | Ankyrin 2. (3933 aa) |
| | PLAUR | Plasminogen activator, urokinase receptor. (331 aa) |
| | SDC4 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (199 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa) |
| | GPC3 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (509 aa) |
| | TLR4 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (841 aa) |
| | SDC1 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (312 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1318 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa) |
| | RDX | Radixin. (602 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1208 aa) |
| | CTSL | Cathepsin L; Belongs to the peptidase C1 family. (333 aa) |
| | IGF2 | Insulin-like growth factor II. (179 aa) |
| | PLCE1 | Phosphoinositide phospholipase C. (1931 aa) |
| | FLNC | Filamin C. (2720 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | CD63 | Tetraspanin. (237 aa) |
| | COL1A1 | Collagen type I alpha 1 chain. (1463 aa) |
| | CD44 | CD44 molecule (Indian blood group). (715 aa) |
| | RRAS2 | RAS related 2. (212 aa) |
| | FN1 | Fibronectin 1. (2478 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | VAV2 | Vav guanine nucleotide exchange factor 2. (872 aa) |
| | ARHGEF1 | Rho guanine nucleotide exchange factor 1. (971 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa) |
| | PDCD4 | Programmed cell death 4. (513 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) |
| | TIMP3 | Tissue inhibitor of metalloproteinase 3 protein. (211 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | HBEGF | Heparin binding EGF like growth factor. (208 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (611 aa) |
| | FASLG | FasL; Belongs to the tumor necrosis factor family. (277 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (416 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (495 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (818 aa) |
| | LUM | Lumican. (342 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (699 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa) |
| | PRKCA | Uncharacterized protein. (605 aa) |
| | GAB1 | GRB2 associated binding protein 1. (751 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1296 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1384 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) |
| | RRAS | RAS related. (218 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) |
| | GPC1 | Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (559 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | COL1A2 | Collagen type I alpha 2 chain. (1128 aa) |
| | ERBB4 | Protein kinase domain-containing protein. (462 aa) |
| | HSPB2 | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (182 aa) |
| | MRAS | Muscle RAS oncogene homolog. (208 aa) |
| | TLR2 | Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (794 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1250 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (555 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (579 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | ITGA2 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1179 aa) |
| | FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (665 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1543 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
