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| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (589 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (232 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa) |
| | RB1 | RB transcriptional corepressor 1. (931 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | CTNNA1 | Catenin alpha 1. (1018 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (161 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (648 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | POLK | DNA polymerase kappa. (905 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1123 aa) |
| | FRAT1 | Uncharacterized protein. (276 aa) |
| | FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa) |
| | HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (814 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (669 aa) |
| | FRAT2 | FRAT regulator of WNT signaling pathway 2. (229 aa) |
| | RXRB | Retinoid X receptor beta. (533 aa) |
| | AXIN1 | Axin 1. (867 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | E2F3 | E2F_TDP domain-containing protein. (460 aa) |
| | SHC3 | SHC adaptor protein 3. (592 aa) |
| | TCF7L1 | Transcription factor 7 like 1. (587 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | TGFBR2 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) |
| | RARB | Retinoic acid receptor beta. (448 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | MLH1 | MutL homolog 1. (758 aa) |
| | ENSCHIP00000009331 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (327 aa) |
| | CDH17 | Cadherin 17. (832 aa) |
| | FZD1 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (552 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa) |
| | SHC1 | SHC adaptor protein 1. (583 aa) |
| | CSNK1A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (353 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (716 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | SHC4 | SHC adaptor protein 4. (630 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (416 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) |
| | MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa) |
| | REG4 | Regenerating family member 4. (158 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | E2F1 | E2F transcription factor 1. (441 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | CTNNA3 | Uncharacterized protein. (530 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | BCL2 | BH4_2 domain-containing protein. (229 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | LOC102183940 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (245 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2305 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (714 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (841 aa) |
| | CDH1 | Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (903 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa) |
| | LOC108634926 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (336 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1318 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1615 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa) |
| | ABCB1 | Uncharacterized protein. (1242 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | AXIN2 | Axin 2. (844 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1208 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | DDB2 | Damage specific DNA binding protein 2. (411 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa) |
| | LOC106502019 | Uncharacterized protein. (1220 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (611 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (416 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (495 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa) |
| | RXRA | NR LBD domain-containing protein. (106 aa) |
| | APC | APC regulator of WNT signaling pathway. (2880 aa) |
| | GAB1 | GRB2 associated binding protein 1. (751 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (411 aa) |
| | CDX2 | Caudal type homeobox 2. (306 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (270 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1384 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (736 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (138 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1250 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (555 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (579 aa) |
| | JUP | Junction plakoglobin. (745 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | RXRG | Retinoid X receptor gamma. (539 aa) |
| | CTNNA2 | Uncharacterized protein. (394 aa) |
| | FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (665 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | TCF7 | Transcription factor 7. (418 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa) |
