STRINGSTRING
PRF1 PRF1 CD40LG CD40LG LAMA1 LAMA1 LOC102172138 LOC102172138 FYN FYN HLA-DMA HLA-DMA CD80 CD80 LOC108633459 LOC108633459 LOC102186442 LOC102186442 EIF4G1 EIF4G1 CCND1 CCND1 HLA-DOB HLA-DOB LOC108633460 LOC108633460 SGCG SGCG LAMA2 LAMA2 CASP9 CASP9 ITGAL ITGAL LOC102169753 LOC102169753 ABL2 ABL2 LOC106503481 LOC106503481 HLA-DRA HLA-DRA LOC102179937 LOC102179937 ACTB ACTB CASP3 CASP3 ITGB2 ITGB2 HLA-DOA HLA-DOA BID BID SGCA SGCA DAG1 DAG1 ICAM1 ICAM1 LOC102180664 LOC102180664 LOC102171703 LOC102171703 CD55 CD55 MYH6 MYH6 EIF4G2 EIF4G2 LOC108633505 LOC108633505 ENSCHIP00000019274 ENSCHIP00000019274 ENSCHIP00000020123 ENSCHIP00000020123 EIF4G3 EIF4G3 CASP8 CASP8 CAV1 CAV1 SGCD SGCD LOC102176782 LOC102176782 LOC102181202 LOC102181202 LOC102181347 LOC102181347 RAC3 RAC3 MYH7 MYH7 ABL1 ABL1 ENSCHIP00000024897 ENSCHIP00000024897 LOC102186727 LOC102186727 CXADR CXADR LOC102185917 LOC102185917 CD40 CD40 LOC102168905 LOC102168905 CD28 CD28 LOC102188814 LOC102188814 RAC2 RAC2 SGCB SGCB LOC102173997 LOC102173997 LOC106501717 LOC106501717 LOC102187998 LOC102187998
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRF1Perforin 1. (554 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
LAMA1Uncharacterized protein. (530 aa)
LOC102172138Ig-like domain-containing protein; Belongs to the MHC class I family. (360 aa)
FYNTyrosine-protein kinase. (537 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (278 aa)
CD80CD80 molecule. (302 aa)
LOC108633459Ig-like domain-containing protein; Belongs to the MHC class I family. (369 aa)
LOC102186442Ig-like domain-containing protein. (290 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1607 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (270 aa)
LOC108633460Ig-like domain-containing protein; Belongs to the MHC class I family. (383 aa)
SGCGSarcoglycan gamma. (291 aa)
LAMA2Laminin subunit alpha 2. (3116 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (452 aa)
ITGALVWFA domain-containing protein; Belongs to the integrin alpha chain family. (1178 aa)
LOC102169753Ig-like domain-containing protein; Belongs to the MHC class I family. (382 aa)
ABL2Tyrosine-protein kinase. (1182 aa)
LOC106503481Ig-like domain-containing protein. (274 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (253 aa)
LOC102179937Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
ACTBUncharacterized protein. (375 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (275 aa)
ITGB2Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] (774 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (332 aa)
BIDUncharacterized protein. (244 aa)
SGCASarcoglycan alpha. (388 aa)
DAG1Dystroglycan 1. (895 aa)
ICAM1Intercellular adhesion molecule 1. (532 aa)
LOC102180664Ig-like domain-containing protein. (266 aa)
LOC102171703Ig-like domain-containing protein; Belongs to the MHC class I family. (382 aa)
CD55Uncharacterized protein. (369 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1943 aa)
EIF4G2Eukaryotic translation initiation factor 4 gamma 2. (905 aa)
LOC108633505Ig-like domain-containing protein; Belongs to the MHC class I family. (324 aa)
ENSCHIP00000019274Ig-like domain-containing protein. (253 aa)
ENSCHIP00000020123Ig-like domain-containing protein; Belongs to the MHC class I family. (348 aa)
EIF4G3Eukaryotic translation initiation factor 4 gamma 3. (1584 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (488 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
SGCDSarcoglycan delta. (289 aa)
LOC102176782Ig-like domain-containing protein; Belongs to the MHC class I family. (357 aa)
LOC102181202Ig-like domain-containing protein; Belongs to the MHC class I family. (392 aa)
LOC102181347Ig-like domain-containing protein; Belongs to the MHC class I family. (374 aa)
RAC3Rac family small GTPase 3. (192 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1955 aa)
ABL1Tyrosine-protein kinase. (1151 aa)
ENSCHIP00000024897Ig-like domain-containing protein; Belongs to the MHC class I family. (361 aa)
LOC102186727Ig-like domain-containing protein; Belongs to the MHC class II family. (322 aa)
CXADRUncharacterized protein. (416 aa)
LOC102185917Ig-like domain-containing protein; Belongs to the MHC class I family. (361 aa)
CD40CD40 molecule. (280 aa)
LOC102168905Ig-like domain-containing protein; Belongs to the MHC class I family. (375 aa)
CD28CD28 molecule. (228 aa)
LOC102188814Ig-like domain-containing protein; Belongs to the MHC class I family. (360 aa)
RAC2Rac family small GTPase 2. (192 aa)
SGCBSarcoglycan beta. (320 aa)
LOC102173997Capra hircus breed Kapro cytochrome c mRNA; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC106501717Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC102187998Ig-like domain-containing protein. (262 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.