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| | surA | Peptidyl-prolyl cis-trans isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (428 aa) |
| | imp | Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (786 aa) |
| | lpxC | UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (305 aa) |
| | yacF | Putative cytoplasmic protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. (247 aa) |
| | htrA | Periplasmic serine protease Do, heat shock protein; DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures. It degrades transiently denatured and unfolded proteins which accumulate in the periplasm following heat shock or other stress conditions. DegP is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for beta-branched side chain amino acids. Only unfolded proteins devoid of disulfide bonds appear capable of being cleaved, thereby preventing non-specific proteolysis of folded proteins. Its proteolyt [...] (475 aa) |
| | yaeH | Similar to E. coli putative structural protein (AAC73274.1); Blastp hit to AAC73274.1 (128 aa), 95% identity in aa 1 - 128; Belongs to the UPF0325 family. (128 aa) |
| | yaeL | Putative membrane-associated Zn-dependent protease; A site-2 regulated intramembrane protease (S2P) that cleaves the peptide bond between 'Ala-108' and 'Cys-109' in the transmembrane region of RseA. Part of a regulated intramembrane proteolysis (RIP) cascade. Acts on DegS-cleaved RseA to release the cytoplasmic domain of RseA. This provides the cell with sigma-E (RpoE) activity through the proteolysis of RseA (By similarity); Belongs to the peptidase M50B family. (450 aa) |
| | yaeT | Putative outer membrane antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. (804 aa) |
| | hlpA | Histone-like protein, located in outer membrane; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm. (161 aa) |
| | lpxD | UDP-3-O-(3-hydroxymyristoyl)-glucosamine n-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (341 aa) |
| | fabZ | (3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity). (151 aa) |
| | lpxA | UDP-N-acetylglucosamine acetyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (262 aa) |
| | lpxB | tetraacyldisaccharide-1-P; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (382 aa) |
| | yafD | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73314.1); Blastp hit to AAC73314.1 (266 aa), 96% identity in aa 8 - 266. (259 aa) |
| | yafA | Putative hydrolase of the alpha/beta superfamily; Displays esterase activity toward pNP-butyrate. (414 aa) |
| | crl | Transcriptional regulator of cryptic csgA gene for curli surface fibers; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes, such as the csgBAC operon encoding the subunits of curli proteins, and BcsA, involved in cellulose biosynthesis. (133 aa) |
| | phoE | Outer membrane pore protein e (e,ic,nmpab); Uptake of inorganic phosphate, phosphorylated compounds, and some other negatively charged solutes; Belongs to the Gram-negative porin family. (350 aa) |
| | tsx | Nucleoside channel; Functions as substrate-specific channel for nucleosides and deoxynucleosides. Functions also in albicidin uptake and as receptor for colicin K; Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family. (287 aa) |
| | lpxH | UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (240 aa) |
| | rlpB | A minor lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family. (196 aa) |
| | ybgC | Putative esterase; Similar to E. coli orf, hypothetical protein (AAC73830.1); Blastp hit to AAC73830.1 (134 aa), 92% identity in aa 1 - 134. (134 aa) |
| | tolQ | Tol protein, membrane-spanning inner membrane protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (230 aa) |
| | tolR | Tol protein, role in outer membrane integrity; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (142 aa) |
| | tolA | Similar to E. coli membrane spanning protein, required for outer membrane integrity (AAC73833.1); Blastp hit to AAC73833.1 (421 aa), 70% identity in aa 1 - 420. (407 aa) |
| | tolB | Tol protein required for outer membrane integrity; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. (430 aa) |
| | pal | Tol protein required for outer membrane integrity; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (174 aa) |
| | ybgF | Putative periplasmic protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (262 aa) |
| | ompX | Outer membrane protease, receptor for phage OX2; Similar to E. coli outer membrane protein X (AAC73901.1); Blastp hit to AAC73901.1 (171 aa), 91% identity in aa 1 - 171. (171 aa) |
| | lolA | Periplasmic protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (204 aa) |
| | msbA | Multicopy repressor of htrB transport protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family. (582 aa) |
| | lpxK | Tetraacyldisaccharide 4' kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (325 aa) |
| | ycaQ | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74002.1); Blastp hit to AAC74002.1 (410 aa), 77% identity in aa 1 - 408. (410 aa) |
| | kdsB | CTP:CMP-3-deoxy-D-manno-octulosonate transferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (248 aa) |
| | STM0989 | mukF protein (killing factor KicB); Similar to E. coli orf, hypothetical protein (AAC74005.1); Blastp hit to AAC74005.1 (297 aa), 90% identity in aa 1 - 297. (297 aa) |
| | ompF | Outer membrane protein 1a (ia;b;f), porin; Forms pores that allow passive diffusion of small molecules across the outer membrane. It is also a receptor for the bacteriophage T2 (By similarity). (363 aa) |
| | ycbW | Putative cytoplasmic protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. (180 aa) |
| | ompA | Putative membrane component hydrogenase; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. (350 aa) |
| | helD | DNA helicase IV; Similar to E. coli DNA helicase IV (AAC74048.1); Blastp hit to AAC74048.1 (684 aa), 83% identity in aa 1 - 684. (684 aa) |
| | htrB | Lauroyl/myristoyl acyltransferase involved in lipid A biosynthesis; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (306 aa) |
| | ycfU | Integral membrane protein ABC transporter; Similar to E. coli orf, hypothetical protein (AAC74200.1); Blastp hit to AAC74200.1 (399 aa), 93% identity in aa 1 - 399. (436 aa) |
| | ycfV | ATP-binding protein ABC transporter; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (233 aa) |
| | ycfW | Integral membrane protein ABC transporter; Similar to E. coli putative kinase (AAC74202.1); Blastp hit to AAC74202.1 (414 aa), 92% identity in aa 1 - 414. (414 aa) |
| | ycfX | Putative regulator (NagC/XylR family); Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. Belongs to the ROK (NagC/XylR) family. NagK subfamily. (303 aa) |
| | lpp | Murein lipoprotein; Plays an important role in virulence. A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non- covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane (By similarity). (78 aa) |
| | ompN | Outer membrane protein N; Non-specific porin; similar to E. coli putative outer membrane protein (AAC74459.1); Blastp hit to AAC74459.1 (377 aa), 81% identity in aa 1 - 377. (377 aa) |
| | nmpC | New outer membrane protein; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family. (362 aa) |
| | yciM | Putative N-acetylglucosaminyl transferase; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. (389 aa) |
| | yciS | Putative inner membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (102 aa) |
| | ompW | Outer membrane protein W; Colicin S4 receptor; putative transporter; similar to E. coli putative outer membrane protein (AAC74338.1); Blastp hit to AAC74338.1 (212 aa), 88% identity in aa 1 - 212. (212 aa) |
| | hns | DNA-binding protein HLP-II; Binds tightly to dsDNA. Acts as a global transcriptional regulator through its ability to bind to AT-rich DNA sequences. Binds in the minor groove of AT-rich DNA. Was found to bind 746 genes, about half of which show no change in expression in disruption experiments suggesting these sites are important for nucleoid structure. On a global level genes bound by H-NS are expressed at a lower than average level; H-NS is excluded from binding to highly transcribed genes and does not co-localize with RNA polymerase in DNA-binding studies during exponential growth i [...] (137 aa) |
| | kdsA | 3-deoxy-D-manno-octulosonic acid 8-P synthetase; Similar to E. coli 2-dehydro-3-deoxyphosphooctulonate aldolase (AAC74299.1); Blastp hit to AAC74299.1 (284 aa), 93% identity in aa 1 - 282; Belongs to the KdsA family. (284 aa) |
| | lolB | Outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. (207 aa) |
| | fadR | Negative regulator of fad regulon; Multifunctional regulator of fatty acid metabolism. Represses transcription of at least eight genes required for fatty acid transport and beta-oxidation including fadA, fadB, fadD, fadL and fadE. Activates transcription of at least three genes required for unsaturated fatty acid biosynthesis: fabA, fabB and iclR, the gene encoding the transcriptional regulator of the aceBAK operon encoding the glyoxylate shunt enzymes. Binding of FadR is specifically inhibited by long chain fatty acyl-CoA compounds (By similarity). (239 aa) |
| | prc | Carboxy-terminal protease for penicillin-binding protein 3; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses (By similarity). (682 aa) |
| | proQ | Activator of proP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. (228 aa) |
| | yebR | Putative GAF domain-containing protein; Similar to E. coli orf, hypothetical protein (AAC74902.1); Blastp hit to AAC74902.1 (183 aa), 83% identity in aa 11 - 183. (194 aa) |
| | cutC | Copper homeostasis protein; Participates in the control of copper homeostasis. (248 aa) |
| | yecM | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74945.1); Blastp hit to AAC74945.1 (190 aa), 84% identity in aa 3 - 190. (189 aa) |
| | ompS | Similar to E. coli putative outer membrane protein (AAC74459.1); Blastp hit to AAC74459.1 (377 aa), 71% identity in aa 1 - 236, 60% identity in aa 174 - 377; Belongs to the Gram-negative porin family. (398 aa) |
| | yejK | Nucleotide associated protein; Present in spermidine nucleoids; similar to E. coli orf, hypothetical protein (AAC75247.1); Blastp hit to AAC75247.1 (335 aa), 96% identity in aa 1 - 334. (335 aa) |
| | yejL | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75248.1); Blastp hit to AAC75248.1 (75 aa), 90% identity in aa 1 - 75; Belongs to the UPF0352 family. (75 aa) |
| | yejM | Putative hydrolase of alkaline phosphatase superfamily; Hypothetical protein in rplY-proL intergenic region. (SW:YEJM_SALTY). (586 aa) |
| | ompC | Outer membrane protein 1b (ib;c); Forms pores that allow passive diffusion of small molecules across the outer membrane. (378 aa) |
| | yfbV | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75355.1); Blastp hit to AAC75355.1 (151 aa), 95% identity in aa 1 - 151. (151 aa) |
| | yfcL | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75385.1); Blastp hit to AAC75385.1 (92 aa), 85% identity in aa 1 - 91. (91 aa) |
| | yfcA | Similar to E. coli putative structural protein (AAC75387.1); Blastp hit to AAC75387.1 (269 aa), 90% identity in aa 1 - 269. (269 aa) |
| | mepA | Penicillin-insensitive murein DD-endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family. (274 aa) |
| | yfcN | Putative Smr domain containing protein; Similar to E. coli orf, hypothetical protein (AAC75391.1); Blastp hit to AAC75391.1 (183 aa), 93% identity in aa 1 - 183; Belongs to the UPF0115 family. (183 aa) |
| | sixA | Phosphohistidine phosphatase; Similar to E. coli orf, hypothetical protein (AAC75400.1); Blastp hit to AAC75400.1 (161 aa), 89% identity in aa 1 - 161. (161 aa) |
| | vacJ | Similar to E. coli lipoprotein precursor (AAC75406.1); Blastp hit to AAC75406.1 (251 aa), 94% identity in aa 1 - 251. (251 aa) |
| | ddg | Cold shock-induced palmitoleoyl transferase; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily. (306 aa) |
| | nlpB | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (344 aa) |
| | yfgL | Putative serine/threonine protein kinase; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (392 aa) |
| | rseC | Similar to E. coli sigma-E factor, negative regulatory protein (AAC75623.1); Blastp hit to AAC75623.1 (159 aa), 81% identity in aa 1 - 159. (159 aa) |
| | rseB | Anti sigma E (sigma 24) factor, negative regulator; Similar to E. coli regulates activity of sigma-E factor (AAC75624.1); Blastp hit to AAC75624.1 (318 aa), 89% identity in aa 1 - 318. (318 aa) |
| | rseA | Anti sigma E (sigma 24) factor, negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytop [...] (216 aa) |
| | rpoE | Sigma E (sigma 24) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase (RNAP) to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma-E controls the envelope stress response, responding to periplasmic protein stress, increased levels of periplasmic lipopolysaccharide (LPS) as well as acid stress, heat shock and oxidative stress; it controls protein processing in the extracytoplasmic compartment (By similarity). (191 aa) |
| | yfiO | Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery. (245 aa) |
| | smpA | Small membrane protein A; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (112 aa) |
| | syd | Interacts with secY; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. (181 aa) |
| | ygfE | Putative cytoplasmic protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (109 aa) |
| | nlpI | Lipoprotein, cell division; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity). (294 aa) |
| | yrbA | Putative BolA family transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC76222.1); Blastp hit to AAC76222.1 (89 aa), 95% identity in aa 3 - 89; Belongs to the BolA/IbaG family. (97 aa) |
| | yrbB | Putative STAS domain protein; Similar to E. coli orf, hypothetical protein (AAC76223.1); Blastp hit to AAC76223.1 (129 aa), 69% identity in aa 33 - 129. (98 aa) |
| | yrbC | Putative ABC superfamily transport protein; Atp&memb; similar to E. coli orf, hypothetical protein (AAC76224.1); Blastp hit to AAC76224.1 (211 aa), 93% identity in aa 1 - 211. (211 aa) |
| | yrbD | Putative ABC superfamily transport protein; Bind_prot; similar to E. coli orf, hypothetical protein (AAC76225.1); Blastp hit to AAC76225.1 (183 aa), 87% identity in aa 1 - 183. (183 aa) |
| | yrbE | Putative ABC superfamily transport protein; Membr; similar to E. coli orf, hypothetical protein (AAC76226.1); Blastp hit to AAC76226.1 (260 aa), 96% identity in aa 1 - 260. (260 aa) |
| | yrbF | Putative ABC superfamily transport protein; Atp_bind; similar to E. coli putative ATP-binding component of a transport system (AAC76227.1); Blastp hit to AAC76227.1 (269 aa), 94% identity in aa 1 - 266. (270 aa) |
| | yrbG | Putative CacA family Na:Ca transport protein; Similar to E. coli orf, hypothetical protein (AAC76228.1); Blastp hit to AAC76228.1 (325 aa), 87% identity in aa 1 - 324. (325 aa) |
| | yrbH | Putative polysialic acid capsule expression protein; Involved in the biosynthesis of 3-deoxy-D-manno-octulosonate (KDO), a unique 8-carbon sugar component of lipopolysaccharides (LPSs). Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P) (By similarity). (328 aa) |
| | yrbI | Putative protein of HAD superfamily; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. (188 aa) |
| | yrbK | Putative inner membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. (191 aa) |
| | yhbN | Putative ABC superfamily transport protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (184 aa) |
| | yhbG | Putative ABC superfamily transport protein; Atp_bind; similar to E. coli putative ATP-binding component of a transport system (AAC76233.1); Blastp hit to AAC76233.1 (241 aa), 98% identity in aa 1 - 241. (241 aa) |
| | yhcB | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76265.1); Blastp hit to AAC76265.1 (134 aa), 97% identity in aa 1 - 134. (134 aa) |
| | degS | Periplasmic serine endoprotease; Similar to E. coli protease (AAC76267.1); Blastp hit to AAC76267.1 (355 aa), 91% identity in aa 1 - 355. (356 aa) |
| | yheO | Putative regulator; Similar to E. coli orf, hypothetical protein (AAC76371.1); Blastp hit to AAC76371.1 (244 aa), 97% identity in aa 5 - 244. (240 aa) |
| | fkpA | Similar to E. coli FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) (AAC76372.1); Blastp hit to AAC76372.1 (270 aa), 90% identity in aa 1 - 270. (272 aa) |
| | kdtA | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (425 aa) |
| | yieM | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76768.1); Blastp hit to AAC76768.1 (427 aa), 89% identity in aa 1 - 427. (474 aa) |
| | yieN | Putative regulator protein; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone; Belongs to the RavA family. (498 aa) |
| | yigA | Putative cytoplasmic protein; Hypothetical protein in dapF-xerC intergenic region. (SW:YIGA_SALTY). (235 aa) |
| | yihI | Putative cytoplasmic protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. (171 aa) |
| | yiiU | Putative cytoplasmic protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. (79 aa) |
| | yijC | Putative TetR/AcrR family transcriptional repressor; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. (211 aa) |
| | yjeP | Similar to E. coli putative periplasmic binding protein (AAC77119.1); Blastp hit to AAC77119.1 (1107 aa), 89% identity in aa 1 - 1107. (1108 aa) |
| | yjgP | Putative permease; Similar to E. coli orf, hypothetical protein (AAC77218.1); Blastp hit to AAC77218.1 (366 aa), 94% identity in aa 1 - 366. (366 aa) |
| | yjgQ | Putative permease; Similar to E. coli orf, hypothetical protein (AAC77219.1); Blastp hit to AAC77219.1 (361 aa), 97% identity in aa 2 - 361. (360 aa) |
