STRINGSTRING
oadB1 oadB1 oadA1 oadA1 oadG1 oadG1 dcoC dcoC dcoB dcoB poxB poxB pps pps pykF pykF ldhA ldhA pykA pykA dld dld maeB maeB pckA pckA ppc ppc
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
oadB1Putative oxalacetate decarboxylase, subunit beta; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (433 aa)
oadA1Putative oxalacetate decarboxylase, subunit alpha; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (591 aa)
oadG1Putative oxalacetate decarboxylase, subunit gamma; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (79 aa)
dcoCOxalacetate decarboxylase: gamma chain; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (81 aa)
dcoBOxalacetate decarboxylase: beta chain; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family. (433 aa)
poxBPyruvate dehydrogenase/oxidase FAD and thiamine PPi cofactors, cytoplasmic in absence of cofactors; Similar to E. coli pyruvate oxidase (AAC73958.1); Blastp hit to AAC73958.1 (572 aa), 94% identity in aa 1 - 572; Belongs to the TPP enzyme family. (572 aa)
ppsPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
pykFPyruvate kinase I; Formerly F; fructose stimulated; pyruvate kinase I. (SW:KPY1_SALTY). (470 aa)
ldhASimilar to E. coli fermentative D-lactate dehydrogenase, NAD-dependent (AAC74462.1); Blastp hit to AAC74462.1 (329 aa), 94% identity in aa 1 - 328; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
pykAPyruvate kinase II; Glucose stimulated; similar to E. coli pyruvate kinase II, glucose stimulated (AAC74924.1); Blastp hit to AAC74924.1 (480 aa), 98% identity in aa 1 - 480. (480 aa)
dldNADH independent D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (576 aa)
maeBPutative transferase; NADP-dependent malic enzyme. (SW:MAO2_SALTY); In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family. (759 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (539 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (883 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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