(12 nodes) Mixed, incl. Asparagine metabolic process, and Histidine metabolism network (Salmonella enterica Typhimurium)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	asnB	Similar to E. coli asparagine synthetase B (AAC73768.1); Blastp hit to AAC73768.1 (554 aa), 94% identity in aa 1 - 554. (554 aa)
	hutI	Imidazolonepropionase; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (407 aa)
	hutG	Formimionoglutamate hydrolase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family. (313 aa)
	hutC	Histidine utilization repressor; Similar to E. coli transcriptional regulator of succinylCoA synthetase operon (AAC73824.1); Blastp hit to AAC73824.1 (240 aa), 24% identity in aa 5 - 229. (241 aa)
	hutH	Histidine ammonia lyase; Belongs to the PAL/histidase family. (506 aa)
	ansA	Similar to E. coli cytoplasmic L-asparaginase I (AAC74837.1); Blastp hit to AAC74837.1 (338 aa), 94% identity in aa 1 - 338. (338 aa)
	ansP	L-asparagine permease (L-asparagine transport protein). (SW:ANSP_SALTY). (497 aa)
	ansB	Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 92% identity in aa 1 - 348. (348 aa)
	STM3598	Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 46% identity in aa 22 - 348. (347 aa)
	asnA	Similar to E. coli asparagine synthetase A (AAC76767.1); Blastp hit to AAC76767.1 (330 aa), 94% identity in aa 1 - 330; Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily. (330 aa)
	aspA	Similar to E. coli aspartate ammonia-lyase (aspartase) (AAC77099.1); Blastp hit to AAC77099.1 (493 aa), 97% identity in aa 16 - 493. (478 aa)
	STM4510	Putative aspartate racemase; Similar to E. coli putative resistance proteins (AAC75879.1); Blastp hit to AAC75879.1 (230 aa), 29% identity in aa 1 - 218; Belongs to the aspartate/glutamate racemases family. (244 aa)

Your Current Organism:

Salmonella enterica Typhimurium

NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
STM3598	STM4510	STM3598	STM4510	Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 46% identity in aa 22 - 348.	Putative aspartate racemase; Similar to E. coli putative resistance proteins (AAC75879.1); Blastp hit to AAC75879.1 (230 aa), 29% identity in aa 1 - 218; Belongs to the aspartate/glutamate racemases family.	0.979
STM3598	ansA	STM3598	STM1294	Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 46% identity in aa 22 - 348.	Similar to E. coli cytoplasmic L-asparaginase I (AAC74837.1); Blastp hit to AAC74837.1 (338 aa), 94% identity in aa 1 - 338.	0.919
STM3598	ansB	STM3598	STM3106	Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 46% identity in aa 22 - 348.	Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 92% identity in aa 1 - 348.	0.908
STM3598	ansP	STM3598	STM1584	Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 46% identity in aa 22 - 348.	L-asparagine permease (L-asparagine transport protein). (SW:ANSP_SALTY).	0.670
STM3598	asnA	STM3598	STM3877	Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 46% identity in aa 22 - 348.	Similar to E. coli asparagine synthetase A (AAC76767.1); Blastp hit to AAC76767.1 (330 aa), 94% identity in aa 1 - 330; Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.	0.900
STM3598	asnB	STM3598	STM0680	Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 46% identity in aa 22 - 348.	Similar to E. coli asparagine synthetase B (AAC73768.1); Blastp hit to AAC73768.1 (554 aa), 94% identity in aa 1 - 554.	0.911
STM3598	aspA	STM3598	STM4326	Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 46% identity in aa 22 - 348.	Similar to E. coli aspartate ammonia-lyase (aspartase) (AAC77099.1); Blastp hit to AAC77099.1 (493 aa), 97% identity in aa 16 - 493.	0.963
STM3598	hutG	STM3598	STM0788	Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 46% identity in aa 22 - 348.	Formimionoglutamate hydrolase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.	0.800
STM4510	STM3598	STM4510	STM3598	Putative aspartate racemase; Similar to E. coli putative resistance proteins (AAC75879.1); Blastp hit to AAC75879.1 (230 aa), 29% identity in aa 1 - 218; Belongs to the aspartate/glutamate racemases family.	Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 46% identity in aa 22 - 348.	0.979
STM4510	ansA	STM4510	STM1294	Putative aspartate racemase; Similar to E. coli putative resistance proteins (AAC75879.1); Blastp hit to AAC75879.1 (230 aa), 29% identity in aa 1 - 218; Belongs to the aspartate/glutamate racemases family.	Similar to E. coli cytoplasmic L-asparaginase I (AAC74837.1); Blastp hit to AAC74837.1 (338 aa), 94% identity in aa 1 - 338.	0.969
STM4510	ansB	STM4510	STM3106	Putative aspartate racemase; Similar to E. coli putative resistance proteins (AAC75879.1); Blastp hit to AAC75879.1 (230 aa), 29% identity in aa 1 - 218; Belongs to the aspartate/glutamate racemases family.	Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 92% identity in aa 1 - 348.	0.947
STM4510	asnA	STM4510	STM3877	Putative aspartate racemase; Similar to E. coli putative resistance proteins (AAC75879.1); Blastp hit to AAC75879.1 (230 aa), 29% identity in aa 1 - 218; Belongs to the aspartate/glutamate racemases family.	Similar to E. coli asparagine synthetase A (AAC76767.1); Blastp hit to AAC76767.1 (330 aa), 94% identity in aa 1 - 330; Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.	0.900
STM4510	asnB	STM4510	STM0680	Putative aspartate racemase; Similar to E. coli putative resistance proteins (AAC75879.1); Blastp hit to AAC75879.1 (230 aa), 29% identity in aa 1 - 218; Belongs to the aspartate/glutamate racemases family.	Similar to E. coli asparagine synthetase B (AAC73768.1); Blastp hit to AAC73768.1 (554 aa), 94% identity in aa 1 - 554.	0.917
STM4510	aspA	STM4510	STM4326	Putative aspartate racemase; Similar to E. coli putative resistance proteins (AAC75879.1); Blastp hit to AAC75879.1 (230 aa), 29% identity in aa 1 - 218; Belongs to the aspartate/glutamate racemases family.	Similar to E. coli aspartate ammonia-lyase (aspartase) (AAC77099.1); Blastp hit to AAC77099.1 (493 aa), 97% identity in aa 16 - 493.	0.932
STM4510	hutG	STM4510	STM0788	Putative aspartate racemase; Similar to E. coli putative resistance proteins (AAC75879.1); Blastp hit to AAC75879.1 (230 aa), 29% identity in aa 1 - 218; Belongs to the aspartate/glutamate racemases family.	Formimionoglutamate hydrolase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.	0.800
ansA	STM3598	STM1294	STM3598	Similar to E. coli cytoplasmic L-asparaginase I (AAC74837.1); Blastp hit to AAC74837.1 (338 aa), 94% identity in aa 1 - 338.	Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 46% identity in aa 22 - 348.	0.919
ansA	STM4510	STM1294	STM4510	Similar to E. coli cytoplasmic L-asparaginase I (AAC74837.1); Blastp hit to AAC74837.1 (338 aa), 94% identity in aa 1 - 338.	Putative aspartate racemase; Similar to E. coli putative resistance proteins (AAC75879.1); Blastp hit to AAC75879.1 (230 aa), 29% identity in aa 1 - 218; Belongs to the aspartate/glutamate racemases family.	0.969
ansA	ansB	STM1294	STM3106	Similar to E. coli cytoplasmic L-asparaginase I (AAC74837.1); Blastp hit to AAC74837.1 (338 aa), 94% identity in aa 1 - 338.	Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 92% identity in aa 1 - 348.	0.938
ansA	ansP	STM1294	STM1584	Similar to E. coli cytoplasmic L-asparaginase I (AAC74837.1); Blastp hit to AAC74837.1 (338 aa), 94% identity in aa 1 - 338.	L-asparagine permease (L-asparagine transport protein). (SW:ANSP_SALTY).	0.688
ansA	asnA	STM1294	STM3877	Similar to E. coli cytoplasmic L-asparaginase I (AAC74837.1); Blastp hit to AAC74837.1 (338 aa), 94% identity in aa 1 - 338.	Similar to E. coli asparagine synthetase A (AAC76767.1); Blastp hit to AAC76767.1 (330 aa), 94% identity in aa 1 - 330; Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.	0.911

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