STRINGSTRING
yegS yegS glpQ glpQ glpT glpT glpA glpA glpB glpB glpC glpC plsC plsC ygiH ygiH glpD glpD gpsA gpsA ushB ushB STM4069 STM4069 STM4070 STM4070 glpK glpK glpF glpF plsB plsB dgkA dgkA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yegSPutative diacylglycerol kinase catalytic domain containing protein; In vitro does not phosphorylate diacylglycerol, sphingosine, N,N-dimethylsphingosine; threo-dihydrosphingosine, erythro- dihydrosphingosine, C2 ceramide, C6 ceramide, phosphatidylinositol or dimethylsphingosine. The potential in vivo substrate is unknown. (299 aa)
glpQSimilar to E. coli glycerophosphodiester phosphodiesterase, periplasmic (AAC75299.1); Blastp hit to AAC75299.1 (358 aa), 89% identity in aa 1 - 357. (356 aa)
glpTMFS family, sn-glycerol-3-phosphate transport protein; Similar to E. coli sn-glycerol-3-phosphate permease (AAC75300.1); Blastp hit to AAC75300.1 (452 aa), 96% identity in aa 1 - 452. (452 aa)
glpASimilar to E. coli sn-glycerol-3-phosphate dehydrogenase (anaerobic), large subunit (AAC75301.1); Blastp hit to AAC75301.1 (542 aa), 92% identity in aa 1 - 542; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (542 aa)
glpBSn-glycerol-3-phosphate dehydrogenase (anaerobic), membrane anchor subunit; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor; Belongs to the anaerobic G-3-P dehydrogenase subunit B family. (419 aa)
glpCSimilar to E. coli sn-glycerol-3-phosphate dehydrogenase (anaerobic), K-small subunit (AAC75303.1); Blastp hit to AAC75303.1 (396 aa), 94% identity in aa 1 - 395. (396 aa)
plsC1-acyl-sn-glycerol-3-phosphate acyltransferase; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-acyl-carrier-protein as the fatty acyl donor. (245 aa)
ygiHPutative inner membrane protein; Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl- PO(4); Belongs to the PlsY family. (203 aa)
glpDAerobic; similar to E. coli sn-glycerol-3-phosphate dehydrogenase (aerobic) (AAC76451.1); Blastp hit to AAC76451.1 (501 aa), 90% identity in aa 1 - 501; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (502 aa)
gpsAGlycerol-3-phosphate dehydrogenase [NAD+]. (SW:GPDA_SALTY); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (339 aa)
ushBCDP-diacylglycerol pyrophosphatase. (SW:CDH_SALTY). (251 aa)
STM4069Putative periplasmic protein. (54 aa)
STM4070Putative cytoplasmic protein; Similar to E. coli CDP-diacylglycerol phosphotidylhydrolase (AAC76900.1); Blastp hit to AAC76900.1 (251 aa), 81% identity in aa 214 - 250. (43 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (502 aa)
glpFSimilar to E. coli facilitated diffusion of glycerol (AAC76909.1); Blastp hit to AAC76909.1 (281 aa), 92% identity in aa 1 - 281; Belongs to the MIP/aquaporin (TC 1.A.8) family. (281 aa)
plsBGlycerolphosphate acyltransferase activity; Similar to E. coli glycerol-3-phosphate acyltransferase (AAC77011.1); Blastp hit to AAC77011.1 (827 aa), 94% identity in aa 21 - 826; Belongs to the GPAT/DAPAT family. (806 aa)
dgkADiacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (122 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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