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| | cueO | Putative multicopper oxidase; Probably involved in periplasmic detoxification of copper by oxidizing Cu(+) to Cu(2+) and thus preventing its uptake into the cytoplasm. Possesses phenoloxidase and ferroxidase activities and might be involved in the production of polyphenolic compounds and the prevention of oxidative damage in the periplasm (By similarity). (536 aa) |
| | fhuA | Iron complex outermembrane recepter protein; Similar to E. coli outer membrane protein receptor for ferrichrome, colicin M, and phages T1, T5, and phi80 (AAC73261.1); Blastp hit to AAC73261.1 (747 aa), 68% identity in aa 1 - 747. (729 aa) |
| | fhuC | Hydroxymate-dependent iron transport; ABC superfamily (atp_bind); similar to E. coli ATP-binding component of hydroxymate-dependent iron transport (AAC73262.1); Blastp hit to AAC73262.1 (265 aa), 92% identity in aa 1 - 265. (265 aa) |
| | fhuD | Hydroxamate-dependent iron uptake; ABC superfamily (bind _prot); similar to E. coli hydroxamate-dependent iron uptake, cytoplasmic membrane component (AAC73263.1); Blastp hit to AAC73263.1 (296 aa), 82% identity in aa 1 - 296. (296 aa) |
| | fhuB | Hydroxamate-dependent iron uptake; Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity). Involved in ferrioxamine-mediated iron(III) utilization. (685 aa) |
| | yadS | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC73268.1); Blastp hit to AAC73268.1 (207 aa), 96% identity in aa 1 - 207. (207 aa) |
| | btuF | Putative cobalamin periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity). (266 aa) |
| | dgt | Deoxyguanosine triphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily. (505 aa) |
| | STM0350 | Homology to outer membrane efflux protein; Similar to E. coli putative resistance protein (AAC73673.1); Blastp hit to AAC73673.1 (457 aa), 37% identity in aa 7 - 457. (503 aa) |
| | STM0351 | Putative cation efflux system protein; Similar to E. coli integral transmembrane protein; acridine resistance (AAC76298.1); Blastp hit to AAC76298.1 (1034 aa), 42% identity in aa 3 - 1030. (1055 aa) |
| | STM0352 | Similar to E. coli acridine efflux pump (AAC73565.1); Blastp hit to AAC73565.1 (397 aa), 31% identity in aa 38 - 383; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (408 aa) |
| | STM0353 | Similar to E. coli putative ATPase (AAC73586.1); Blastp hit to AAC73586.1 (834 aa), 42% identity in aa 99 - 831, 45% identity in aa 4 - 63. (762 aa) |
| | STM0354 | Similar to E. coli putative transcriptional regulator (AAC73589.1); Blastp hit to AAC73589.1 (135 aa), 42% identity in aa 1 - 126. (154 aa) |
| | STM0355 | Putative copper chaperone. (64 aa) |
| | STM0363 | Putative XylS/AraC transcriptional activator (gi|3094022). (334 aa) |
| | foxA | Ferrioxamine receptor; Ferrioxamine binding and uptake, in association with the TonB protein; Belongs to the TonB-dependent receptor family. (702 aa) |
| | yahN | Putative transport protein; Similar to E. coli putative cytochrome subunit of dehydrogenase (AAC73431.1); Blastp hit to AAC73431.1 (223 aa), 86% identity in aa 14 - 223. (210 aa) |
| | STM0409 | Hypothetical protein. (121 aa) |
| | STM0410 | Putative regulatory protein. (230 aa) |
| | ybaO | Similar to E. coli putative LRP-like transcriptional regulator (AAC73550.1); Blastp hit to AAC73550.1 (181 aa), 95% identity in aa 30 - 181. (152 aa) |
| | mdlA | Putative ABC superfamily (atp) transporter; Similar to E. coli ATP-binding component of a transport system (AAC73551.1); Blastp hit to AAC73551.1 (590 aa), 88% identity in aa 1 - 590. (590 aa) |
| | mdlB | Putative ABC superfamily (atp&membrane) transporter; Similar to E. coli putative ATP-binding component of a transport system (AAC73552.1); Blastp hit to AAC73552.1 (593 aa), 88% identity in aa 1 - 593. (593 aa) |
| | ybaZ | Putative methyltransferase; Similar to E. coli orf, hypothetical protein (AAC73557.1); Blastp hit to AAC73557.1 (129 aa), 82% identity in aa 1 - 129. (129 aa) |
| | acrB | Similar to E. coli acridine efflux pump (AAC73564.1); Blastp hit to AAC73564.1 (1049 aa), 94% identity in aa 1 - 1048. (1049 aa) |
| | acrA | Similar to E. coli acridine efflux pump (AAC73565.1); Blastp hit to AAC73565.1 (397 aa), 91% identity in aa 1 - 397; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (397 aa) |
| | acrR | Similar to E. coli acrAB operon repressor (AAC73566.1); Blastp hit to AAC73566.1 (215 aa), 87% identity in aa 1 - 214. (217 aa) |
| | STM0479 | Putative transposase; Similar to E. coli orf, hypothetical protein (AAC75365.1); Blastp hit to AAC75365.1 (296 aa), 49% identity in aa 7 - 296. (311 aa) |
| | ybaN | Similar to E. coli putative gene 58 (AAC73570.1); Blastp hit to AAC73570.1 (125 aa), 84% identity in aa 1 - 124. (125 aa) |
| | copA | Putative copper-transporting ATPase; [Copper-exporting P-type ATPase]: Involved in Cu(+) export (By similarity). Essential for copper tolerance under both aerobic and anaerobic conditions. (833 aa) |
| | cueR | Putative heavy metal transcriptional repressor (MerR family); Regulates the transcription of the copA and cuiD (cueO) genes. Detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations. (138 aa) |
| | entD | Enterochelin synthetase, component D (phoshpantetheinyltransferase); Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3- dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo- domains of both EntB (ArCP domain) and EntF (PC [...] (234 aa) |
| | fepA | Similar to E. coli outer membrane receptor for ferric enterobactin (enterochelin) and colicins B and D (AAC73685.1); Blastp hit to AAC73685.1 (746 aa), 81% identity in aa 1 - 746. (751 aa) |
| | fes | Similar to E. coli enterochelin esterase (AAC73686.1); Blastp hit to AAC73686.1 (374 aa), 74% identity in aa 2 - 369. (404 aa) |
| | ybdZ | Putative cytoplasmic protein. (72 aa) |
| | entF | Enterobactin synthetase, component F (nonribosomal peptide synthetase); Similar to E. coli ATP-dependent serine activating enzyme (may be part of enterobactin synthase as component F) (AAC73687.1); Blastp hit to AAC73687.1 (1293 aa), 79% identity in aa 1 - 1293. (1294 aa) |
| | fepC | Enterobactin transporter; ABC superfamily (atp_bind); similar to E. coli ATP-binding component of ferric enterobactin transport (AAC73689.1); Blastp hit to AAC73689.1 (271 aa), 92% identity in aa 1 - 263. (264 aa) |
| | fepG | Ferric enterobactin transporter; ABC superfamily (membrane); similar to E. coli ferric enterobactin transport protein (AAC73690.1); Blastp hit to AAC73690.1 (330 aa), 86% identity in aa 2 - 330; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (329 aa) |
| | fepD | ABC superfamily (membrane); similar to E. coli ferric enterobactin (enterochelin) transport (AAC73691.1); Blastp hit to AAC73691.1 (334 aa), 88% identity in aa 1 - 333; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (335 aa) |
| | ybdA | Putative POT family transport protein; Component of an export pathway for enterobactin. Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family. (414 aa) |
| | fepB | ABC superfamily (peri_perm); similar to E. coli ferric enterobactin (enterochelin) binding protein; periplasmic component (AAC73693.1); Blastp hit to AAC73693.1 (318 aa), 79% identity in aa 1 - 318. (318 aa) |
| | entC | Similar to E. coli isochorismate hydroxymutase 2, enterochelin biosynthesis (AAC73694.1); Blastp hit to AAC73694.1 (391 aa), 84% identity in aa 1 - 391. (391 aa) |
| | entE | Similar to E. coli 2,3-dihydroxybenzoate-AMP ligase (AAC73695.1); Blastp hit to AAC73695.1 (536 aa), 86% identity in aa 1 - 534. (536 aa) |
| | entB | Similar to E. coli 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase (AAC73696.1); Blastp hit to AAC73696.1 (285 aa), 88% identity in aa 1 - 285. (285 aa) |
| | entA | Similar to E. coli 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase, enterochelin biosynthesis (AAC73697.1); Blastp hit to AAC73697.1 (248 aa), 90% identity in aa 2 - 248. (251 aa) |
| | ybdB | Putative protein PaaI, possibly involved in aromatic compounds catabolism; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. (137 aa) |
| | phrB | Deoxyribodipyrimidine photolyase (photoreactivation); Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation; Belongs to the DNA photolyase class-1 family. (473 aa) |
| | ybgR | Putative CDF family transport protein; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. (312 aa) |
| | STM0770 | Putative ABC transport protein; Similar to E. coli ferric enterobactin (enterochelin) transport (AAC73691.1); Blastp hit to AAC73691.1 (334 aa), 37% identity in aa 9 - 332; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (359 aa) |
| | STM0771 | Putative ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component; Similar to E. coli ATP-binding component of ferric enterobactin transport (AAC73689.1); Blastp hit to AAC73689.1 (271 aa), 34% identity in aa 8 - 244. (258 aa) |
| | acrZ | Putative outer membrane or exported; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export. (49 aa) |
| | mntR | Putative Mn-dependent transcriptional regulator; In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP (By similarity). Belongs to the DtxR/MntR family. (157 aa) |
| | ybiR | Putative di- and tricarboxylate transporters; Similar to E. coli orf, hypothetical protein (AAC73905.1); Blastp hit to AAC73905.1 (372 aa), 83% identity in aa 1 - 370. (370 aa) |
| | mdfA | Multidrug translocase; Similar to E. coli proton motive force efflux pump (AAC73929.1); Blastp hit to AAC73929.1 (410 aa), 90% identity in aa 1 - 406. (410 aa) |
| | STM0901 | Fels-1 putative prophage DNA primase. (322 aa) |
| | STM0924 | Putative Fels-1 prophage Cu/Zn superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (174 aa) |
| | ybjY | Similar to E. coli putative membrane protein (AAC73965.1); Blastp hit to AAC73965.1 (380 aa), 83% identity in aa 12 - 378; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (372 aa) |
| | ybjZ | Putative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (648 aa) |
| | yceE | Similar to E. coli putative transport protein (AAC74137.1); Blastp hit to AAC74137.1 (408 aa), 27% identity in aa 1 - 404. (404 aa) |
| | yceL | Putative MFS superfamily transport protein; Similar to E. coli orf, hypothetical protein (AAC74149.1); Blastp hit to AAC74149.1 (412 aa), 92% identity in aa 11 - 412. (402 aa) |
| | fhuE | Outer membrane receptor for Fe(III)-coprogen; Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid uptake; similar to E. coli outer membrane receptor for ferric iron uptake (AAC74186.1); Blastp hit to AAC74186.1 (729 aa), 81% identity in aa 5 - 729. (724 aa) |
| | aadA | Aminoglycoside adenyltransferase; Mediates bacterial resistance to the antibiotics streptomycin and spectomycin. (262 aa) |
| | STM1265 | Putative response regulators; Contains a CheY-like receiver domain and a HTH DNA-binding domain. (197 aa) |
| | STM1266 | Similar to E. coli putative transcriptional regulator (AAC74246.1); Blastp hit to AAC74246.1 (243 aa), 31% identity in aa 1 - 241. (282 aa) |
| | yeaS | Putative transport protein; Exporter of leucine; Belongs to the Rht family. (212 aa) |
| | btuC | Vitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. (326 aa) |
| | btuD | Vitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (249 aa) |
| | orf319 | Putative inner membrane protein; ORF 319 (gi|4456867). (319 aa) |
| | orf242 | Putative regulatory proteins, merR family; ORF 242 (gi|4456866). (242 aa) |
| | ydhE | Putative MATE family transport protein; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily. (457 aa) |
| | ydhC | Similar to E. coli putative transport protein (AAC74732.1); Blastp hit to AAC74732.1 (403 aa), 85% identity in aa 1 - 403. (401 aa) |
| | ydgF | Putative membrane transporter of cations and cationic drugs; Catalyzes the excretion of spermidine. (120 aa) |
| | ydgE | Putative membrane transporter of cations and cationic drugs; Catalyzes the excretion of spermidine. (109 aa) |
| | ydfJ | Similar to E. coli putative transport protein (AAC74616.1); Blastp hit to AAC74616.1 (427 aa), 86% identity in aa 1 - 293. (325 aa) |
| | ydeD | Putative permease, integral membrane protein; May be an export pump for several amino acids and their metabolites, including cysteine; Belongs to the EamA transporter family. (300 aa) |
| | marB | Multiple antibiotic resistance protein MARB. (SW:MARB_SALTY). (71 aa) |
| | marA | AraC/XylS family transcriptional activator of defense systems; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF. (144 aa) |
| | marR | Transcriptional repressor of marRAB operon; Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site. (144 aa) |
| | marC | Putative MarC Transporter; Multiple antibiotic resistance protein MARC. (SW:MARC_SALTY). (221 aa) |
| | STM1530 | Similar to E. coli putative outer membrane protein (AAC74459.1); Blastp hit to AAC74459.1 (377 aa), 61% identity in aa 2 - 377; Belongs to the Gram-negative porin family. (372 aa) |
| | yddG | Putative permease; Similar to E. coli orf, hypothetical protein (AAD13437.1); Blastp hit to AAD13437.1 (293 aa), 85% identity in aa 20 - 292. (274 aa) |
| | smvA | Methyl viologen resistance protein; Major efflux pump for acriflavine and other quaternary ammonium compounds (QACs). Also required for resistance to methyl viologen (By similarity); Belongs to the major facilitator superfamily. TCR/Tet family. (495 aa) |
| | yddE | Putative phenazine biosynthesis protein; Hypothetical protein in nhoA 5'region. (SW:YDDE_SALTY). (297 aa) |
| | yncE | Putative periplasmic protein; Similar to E. coli putative receptor (AAC74534.1); Blastp hit to AAC74534.1 (353 aa), 89% identity in aa 1 - 353. (353 aa) |
| | yncD | Similar to E. coli putative outer membrane receptor for iron transport (AAC74533.1); Blastp hit to AAC74533.1 (700 aa), 84% identity in aa 1 - 700. (706 aa) |
| | STM1653 | Putative membrane transporter of cations; Similar to E. coli methylviologen resistance (AAC73644.1); Blastp hit to AAC73644.1 (110 aa), 59% identity in aa 5 - 110. (112 aa) |
| | zntB | Putative Zn transport protein; Mediates efflux of zinc ions. (327 aa) |
| | tonB | TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates such as cobalamin, and various iron compounds (such as iron dicitrate, enterochelin, aerobactin, etc.). In the absence of TonB these receptors bind their substrates but do not carry out active transport. TonB also interacts with some colicins and is involved in the energy-dependent, irreversible steps of bacteriophages phi 80 and T1 infection. It could act to transduce energy from the cytoplasmic membrane to specific en [...] (242 aa) |
| | dadX | Alanine racemase 2; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. (356 aa) |
| | dadA | D-amino acid dehydrogenase subunit; Oxidative deamination of D-amino acids. (432 aa) |
| | yebN | Putative YebN family transport protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family. (206 aa) |
| | STM1843 | Similar to E. coli putative transport protein (AAC74898.1); Blastp hit to AAC74898.1 (494 aa), 90% identity in aa 38 - 494. (457 aa) |
| | pagO | Predicted integral membrane protein; PAGO protein. (SW:PAGO_SALTY). (304 aa) |
| | STM1863 | Putative inner membrane protein. (52 aa) |
| | STM1864 | Putative inner membrane protein. (204 aa) |
| | znuA | ABC superfamily high affinity Zn transport protein; Binding protein; similar to E. coli putative adhesin (AAC74927.1); Blastp hit to AAC74927.1 (328 aa), 85% identity in aa 1 - 328. (333 aa) |
| | znuC | ABC superfamily high affinity Zn transport protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system (Probable). Seems to be important for the virulence. (268 aa) |
| | znuB | ABC superfamily high affinity Zn transport protein; ATP-binding protein; similar to E. coli orf, hypothetical protein (AAC74929.1); Blastp hit to AAC74929.1 (261 aa), 96% identity in aa 1 - 261. (261 aa) |
| | alkA | Inducible; similar to E. coli 3-methyl-adenine DNA glycosylase II, inducible (AAC75129.1); Blastp hit to AAC75129.1 (282 aa), 74% identity in aa 1 - 279. (289 aa) |
| | mdtA | Putative HlyD family secretion protein; Similar to E. coli putative membrane protein (AAC75135.1); Blastp hit to AAC75135.1 (464 aa), 82% identity in aa 50 - 464; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (413 aa) |
| | yegN | Putative outer membrane receptor; Similar to E. coli orf, hypothetical protein (AAC75136.1); Blastp hit to AAC75136.1 (1040 aa), 91% identity in aa 1 - 1040; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily. (1040 aa) |
| | yegO | Putative resistance protein; Efflux transporter; outer membrane; similar to E. coli orf, hypothetical protein (AAC75137.1); Blastp hit to AAC75137.1 (1025 aa), 91% identity in aa 1 - 1025; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily. (1026 aa) |
| | yegB | Similar to E. coli putative transport protein (AAC75138.1); Blastp hit to AAC75138.1 (471 aa), 85% identity in aa 1 - 469. (470 aa) |
| | baeS | Sensory kinase in two-component regulatoyr system wtih BaeR; Similar to E. coli sensor protein (for BaeR) (AAC75139.1); Blastp hit to AAC75139.1 (467 aa), 88% identity in aa 1 - 467. (467 aa) |
| | baeR | OmpR family; similar to E. coli transcriptional response regulatory protein (sensor BaeS) (AAC75140.1); Blastp hit to AAC75140.1 (240 aa), 96% identity in aa 1 - 240. (240 aa) |
| | cirA | Outer membrane porin; Receptor for colicin I; requires TonB; similar to E. coli outer membrane receptor for iron-regulated colicin I receptor; porin; requires tonB gene product (AAC75216.1); Blastp hit to AAC75216.1 (663 aa), 88% identity in aa 1 - 663. (663 aa) |
| | yojI | ATPase component; similar to E. coli putative ATP-binding component of a transport system (AAC75271.1); Blastp hit to AAC75271.1 (547 aa), 90% identity in aa 1 - 547. (547 aa) |
| | alkB | DNA repair system specific for alkylated DNA; Dioxygenase that repairs alkylated DNA and RNA containing 3- methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing ethenoadenine, and no detectable activity towards 1-methylguanine or 3-methylthymine. Accepts double-stranded and single-stranded substrates. Requires molecular oxygen, alpha- ketoglutarate and iron. Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents), but not to MMNG and MNU (SN1 agents) (B [...] (216 aa) |
| | ada | O6-methylguanine-DNA methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated; In the C-terminal section; belongs to the MGMT family. (353 aa) |
| | gyrA | DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state, and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings. Replenishes negative supercoiling downstream of highly transcribed genes to help control overall chromosomal supercoiling density. E.coli makes 15% more negative supercoils in pBR322 plasmid DNA than S.typhimurium; the S.typhimurium GyrB s [...] (878 aa) |
| | ypeC | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75449.1); Blastp hit to AAC75449.1 (108 aa), 91% identity in aa 1 - 108. (108 aa) |
| | mntH | Manganese/divalent cation transport protein; H(+)-stimulated, divalent metal cation uptake system. Involved in manganese and iron uptake; Belongs to the NRAMP family. (413 aa) |
| | acrD | RND family aminoglycoside/multidrug efflux pump; Similar to E. coli sensitivity to acriflavine, integral membrane protein, possible efflux pump (AAC75523.1); Blastp hit to AAC75523.1 (1037 aa), 94% identity in aa 1 - 1037. (1037 aa) |
| | yfiK | Putative transport protein; Exporter of O-acetylserine (OAS) and cysteine; Belongs to the Rht family. (195 aa) |
| | iroB | Putative glycosyl transferase; Related to UDP-glucuronosyltransferase. (371 aa) |
| | iroC | Putative ATP binding cassette (ABC) transporter; Similar to E. coli ATP-binding transport protein; multicopy suppressor of htrB (AAC74000.1); Blastp hit to AAC74000.1 (582 aa), 26% identity in aa 14 - 582, 29% identity in aa 34 - 565. (1217 aa) |
| | iroD | Enterochelin esterase-like protein (Fes); Similar to E. coli enterochelin esterase (AAC73686.1); Blastp hit to AAC73686.1 (374 aa), 31% identity in aa 3 - 362. (414 aa) |
| | iroE | Putative hydrolase of the alpha/beta superfamily. (311 aa) |
| | iroN | TonB-dependent siderophore receptor protein; Similar to E. coli outer membrane receptor for ferric enterobactin (enterochelin) and colicins B and D (AAC73685.1); Blastp hit to AAC73685.1 (746 aa), 52% identity in aa 3 - 728, 44% identity in aa 245 - 746. (726 aa) |
| | STM2803 | Putative gntR family regulatory protein; Similar to E. coli putative regulator (AAC77296.1); Blastp hit to AAC77296.1 (470 aa), 31% identity in aa 119 - 437, 27% identity in aa 1 - 224. (444 aa) |
| | emrR | Transcriptional repressor of emrAB operon; MarR family; similar to E. coli regulator of plasmid mcrB operon (microcin B17 synthesis) (AAC75731.1); Blastp hit to AAC75731.1 (176 aa), 93% identity in aa 1 - 175. (176 aa) |
| | emrA | Similar to E. coli multidrug resistance secretion protein (AAC75732.1); Blastp hit to AAC75732.1 (390 aa), 89% identity in aa 1 - 390. (390 aa) |
| | emrB | Putative MFS superfamily multidrug transport protein; Similar to E. coli multidrug resistance; probably membrane translocase (AAC75733.1); Blastp hit to AAC75733.1 (512 aa), 95% identity in aa 1 - 512; Belongs to the major facilitator superfamily. (512 aa) |
| | sitA | Fur regulated Salmonella iron transporter; SitA (gi|5231094); Belongs to the bacterial solute-binding protein 9 family. (305 aa) |
| | sitB | Fur regulated Salmonella iron transporter; SitB (gi|5231095). (273 aa) |
| | sitC | Fur regulated Salmonella iron transporter; SitC (gi|5231096). (286 aa) |
| | sitD | Fur regulated Salmonella iron transporter; SitD (gi|5231097). (282 aa) |
| | yohL | Putative cytoplasmic protein; Repressor of rcnA expression. Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt. In the presence of one of these metals, it has a weaker affinity for rcnA promoter (By similarity); Belongs to the FrmR/RcnR family. (90 aa) |
| | yohM | Putative inner membrane protein; Efflux system for nickel and cobalt. (288 aa) |
| | STM3030 | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75434.1); Blastp hit to AAC75434.1 (211 aa), 46% identity in aa 47 - 208. (210 aa) |
| | STM3031 | Ail and ompX-like protein; Similar to E. coli outer membrane protein X (AAC73901.1); Blastp hit to AAC73901.1 (171 aa), 29% identity in aa 1 - 171. (178 aa) |
| | yqfB | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75938.1); Blastp hit to AAC75938.1 (103 aa), 88% identity in aa 1 - 103; Belongs to the UPF0267 family. (103 aa) |
| | iciA | Inhibitor of replication initiation; Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. (297 aa) |
| | yggA | Putative LYSE family amino acid transport protein; Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine (By similarity); Belongs to the LysE/ArgO transporter (TC 2.A.75) family. (211 aa) |
| | exbD | tonB-dependent uptake of B colicins; similar to E. coli uptake of enterochelin; tonB-dependent uptake of B colicins (AAC76041.1); Blastp hit to AAC76041.1 (141 aa), 93% identity in aa 1 - 141. (141 aa) |
| | exbB | Uptake of enterochelin; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity). (244 aa) |
| | parC | DNA topoisomerase IV, subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (752 aa) |
| | parE | DNA topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. Belongs to the type II topoisomerase family. ParE type 1 subfamily. (630 aa) |
| | tolC | Outer membrane channel; Specific tolerance to colicin E1; segregation of daughter chromosomes; role in organic solvent tolerance; similar to E. coli outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (AAC76071.1); Blastp hit to AAC76071.1 (495 aa), 89% identity in aa 1 - 495. (491 aa) |
| | ygiE | Putative divalent heavy-metal cations transporter; Mediates zinc uptake. May also transport other divalent cations such as copper and cadmium ions (By similarity); Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily. (257 aa) |
| | yqjH | Putative transporter; Similar to E. coli orf, hypothetical protein (AAC76105.1); Blastp hit to AAC76105.1 (254 aa), 72% identity in aa 6 - 254. (255 aa) |
| | yqjI | Putative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC76106.1); Blastp hit to AAC76106.1 (207 aa), 68% identity in aa 1 - 207. (215 aa) |
| | yhcP | Putative inner membrane protein; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family. (655 aa) |
| | yhcQ | Putative membrane located multidrug resistance protein; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (310 aa) |
| | yhcR | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76274.1); Blastp hit to AAC76274.1 (90 aa), 98% identity in aa 24 - 90. (67 aa) |
| | acrE | Similar to E. coli transmembrane protein affects septum formation and cell membrane permeability (AAC76297.1); Blastp hit to AAC76297.1 (385 aa), 88% identity in aa 1 - 380; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (385 aa) |
| | acrF | RND family multidrug transport protein; Similar to E. coli integral transmembrane protein; acridine resistance (AAC76298.1); Blastp hit to AAC76298.1 (1034 aa), 22% identity in aa 1 - 506; acriflavin resistance protein F. (1037 aa) |
| | zntR | MerR family; similar to E. coli putative transcriptional regulator (AAC76317.1); Blastp hit to AAC76317.1 (141 aa), 92% identity in aa 1 - 141. (141 aa) |
| | yhdN | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76318.1); Blastp hit to AAC76318.1 (122 aa), 86% identity in aa 1 - 122. (122 aa) |
| | yrfE | Putative NTP pyrophosphohydrolase; Similar to E. coli orf, hypothetical protein (AAC76422.1); Blastp hit to AAC76422.1 (186 aa), 92% identity in aa 1 - 186. (198 aa) |
| | feoA | Similar to E. coli ferrous iron transport protein A (AAC76433.1); Blastp hit to AAC76433.1 (75 aa), 96% identity in aa 1 - 75. (75 aa) |
| | feoB | Ferrous iron transport protein B; Probable transporter for a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (772 aa) |
| | yhgG | Putative cytoplasmic protein; May function as a transcriptional regulator that controls feoABC expression. (78 aa) |
| | STM3508 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75365.1); Blastp hit to AAC75365.1 (296 aa), 67% identity in aa 1 - 296. (304 aa) |
| | zntA | P-type ATPase family; Pb/Cd/Zn/Hg transporting ATPase; similar to E. coli zinc-transporting ATPase (AAC76494.1); Blastp hit to AAC76494.1 (732 aa), 84% identity in aa 1 - 731. (732 aa) |
| | yhhS | Putative MFS family transport protein; Similar to E. coli putative transport (AAC76498.1); Blastp hit to AAC76498.1 (419 aa), 89% identity in aa 1 - 419. (419 aa) |
| | yhhT | Putative PerM family permease; Similar to E. coli orf, hypothetical protein (AAC76499.1); Blastp hit to AAC76499.1 (376 aa), 89% identity in aa 28 - 376. (349 aa) |
| | acpT | Putative phosphopantetheinyl transferase; May be involved in an alternative pathway for phosphopantetheinyl transfer and holo-ACP synthesis. The native apo- protein substrate is unknown; Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family. (192 aa) |
| | nikR | Nickel-responsive transcriptional regulator; Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel. (133 aa) |
| | tag | Similar to E. coli 3-methyl-adenine DNA glycosylase I, constitutive (AAC76573.1); Blastp hit to AAC76573.1 (187 aa), 85% identity in aa 1 - 186. (193 aa) |
| | STM3650 | Putative periplasmic or exported protein. (179 aa) |
| | ysaB | Putative outer membrane lipoprotein. (100 aa) |
| | yiaB | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76587.1); Blastp hit to AAC76587.1 (117 aa), 33% identity in aa 15 - 109. (117 aa) |
| | STM3766 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75365.1); Blastp hit to AAC75365.1 (296 aa), 67% identity in aa 1 - 278, 45% identity in aa 216 - 296. (313 aa) |
| | emrD | MFS family multidrug tranport protein; Similar to E. coli 2-module integral membrane pump; multidrug resistance (AAC76696.1); Blastp hit to AAC76696.1 (396 aa), 92% identity in aa 3 - 396. (394 aa) |
| | gyrB | DNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state, and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings. Replenishes negative supercoiling downstream of highly transcribed genes to help control overall chromosomal supercoiling density. E.coli makes 15% more negative supercoils in pBR322 plasmid DNA than S.typhimurium; the S.typhimurium GyrB s [...] (804 aa) |
| | yidY | Putative MFS family tranport protein; 1st mdule; similar to E. coli putative transport protein (AAC76733.1); Blastp hit to AAC76733.1 (391 aa), 77% identity in aa 1 - 391. (395 aa) |
| | yidZ | Putative LysR family transcriptional regulator; Involved in anaerobic NO protection. (319 aa) |
| | yieE | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76735.1); Blastp hit to AAC76735.1 (253 aa), 77% identity in aa 5 - 253. (251 aa) |
| | yieF | Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC76736.1); Blastp hit to AAC76736.1 (188 aa), 92% identity in aa 1 - 187. (194 aa) |
| | yieO | Putative MFS family tranport protein; 1st mdule; similar to E. coli putative transport protein (AAC76777.1); Blastp hit to AAC76777.1 (475 aa), 86% identity in aa 1 - 475; Belongs to the major facilitator superfamily. (475 aa) |
| | yigF | Putative inner membrane protein; Hypothetical 14.6 Kda protein in corA-rarD intergenic region. (SW:YIGF_SALTY). (126 aa) |
| | yigG | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76821.1); Blastp hit to AAC76821.1 (138 aa), 57% identity in aa 7 - 136. (152 aa) |
| | rarD | Chloramphenicol resistance; Similar to E. coli orf, hypothetical protein (AAC76822.1); Blastp hit to AAC76822.1 (300 aa), 83% identity in aa 8 - 297. (294 aa) |
| | yigI | Putative PaaI protein; Possibly involved in aromatic compounds catabolism; hypothetical protein in rarD-pldA intergenic region. (SW:YIGI_SALTY). (161 aa) |
| | rhtC | RhtB family threonine efflux protein; Conducts the efflux of threonine; Belongs to the Rht family. (206 aa) |
| | rthB | Homoserine/homoserine lactone efflux protein; Conducts the efflux of homoserine and homoserine lactone. Belongs to the Rht family. (206 aa) |
| | yiiP | Putative CDF family transport protein; Cation-efflux transporter that may have a role in detoxification. (300 aa) |
| | trmA | tRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs. (366 aa) |
| | btuB | Outer membrane receptor for transport of vitamin B12, E colicins, and bacteriophage BF23; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (614 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (283 aa) |
| | yjcB | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77030.1); Blastp hit to AAC77030.1 (116 aa), 83% identity in aa 24 - 116. (93 aa) |
| | STM4320 | Putative merR family bacterial regulatory protein; Similar to E. coli putative transcriptional regulator (AAC73589.1); Blastp hit to AAC73589.1 (135 aa), 26% identity in aa 1 - 110. (110 aa) |
| | ytfF | Putative cationic amino acid transporter; Similar to E. coli putative transmembrane subunit (AAC77167.1); Blastp hit to AAC77167.1 (324 aa), 81% identity in aa 4 - 323. (321 aa) |
| | STM4506 | Putative dienelactone hydrolase. (224 aa) |
| | yjiO | Similar to E. coli putative transport protein (AAC77293.1); Blastp hit to AAC77293.1 (410 aa), 86% identity in aa 3 - 410. (413 aa) |
| | STM4549 | Putative cytoplasmic protein. (152 aa) |
| | fhuF | Ferric hydrozamate transport protein; Involved in reduction of ferric iron in cytoplasmic ferrioxamine B; similar to E. coli orf, hypothetical protein (AAC77323.1); Blastp hit to AAC77323.1 (262 aa), 73% identity in aa 1 - 262. (262 aa) |
| | STM4552 | Putative inner membrane protein. (78 aa) |
