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ybgR ybgR mntR mntR zntB zntB yebN yebN znuA znuA znuC znuC znuB znuB mntH mntH sitA sitA sitB sitB sitC sitC sitD sitD ygiE ygiE zntA zntA yiiP yiiP
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ybgRPutative CDF family transport protein; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. (312 aa)
mntRPutative Mn-dependent transcriptional regulator; In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP (By similarity). Belongs to the DtxR/MntR family. (157 aa)
zntBPutative Zn transport protein; Mediates efflux of zinc ions. (327 aa)
yebNPutative YebN family transport protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family. (206 aa)
znuAABC superfamily high affinity Zn transport protein; Binding protein; similar to E. coli putative adhesin (AAC74927.1); Blastp hit to AAC74927.1 (328 aa), 85% identity in aa 1 - 328. (333 aa)
znuCABC superfamily high affinity Zn transport protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system (Probable). Seems to be important for the virulence. (268 aa)
znuBABC superfamily high affinity Zn transport protein; ATP-binding protein; similar to E. coli orf, hypothetical protein (AAC74929.1); Blastp hit to AAC74929.1 (261 aa), 96% identity in aa 1 - 261. (261 aa)
mntHManganese/divalent cation transport protein; H(+)-stimulated, divalent metal cation uptake system. Involved in manganese and iron uptake; Belongs to the NRAMP family. (413 aa)
sitAFur regulated Salmonella iron transporter; SitA (gi|5231094); Belongs to the bacterial solute-binding protein 9 family. (305 aa)
sitBFur regulated Salmonella iron transporter; SitB (gi|5231095). (273 aa)
sitCFur regulated Salmonella iron transporter; SitC (gi|5231096). (286 aa)
sitDFur regulated Salmonella iron transporter; SitD (gi|5231097). (282 aa)
ygiEPutative divalent heavy-metal cations transporter; Mediates zinc uptake. May also transport other divalent cations such as copper and cadmium ions (By similarity); Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily. (257 aa)
zntAP-type ATPase family; Pb/Cd/Zn/Hg transporting ATPase; similar to E. coli zinc-transporting ATPase (AAC76494.1); Blastp hit to AAC76494.1 (732 aa), 84% identity in aa 1 - 731. (732 aa)
yiiPPutative CDF family transport protein; Cation-efflux transporter that may have a role in detoxification. (300 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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