STRINGSTRING
yeaD yeaD ydcX ydcX sdaA sdaA STM2196 STM2196 STM2361 STM2361 sdaC sdaC sdaB sdaB yhaN yhaN yhaO yhaO tdcG tdcG tdcC tdcC tdcB tdcB tdcA tdcA yrdA yrdA STM3799 STM3799 dsdC dsdC dsdX dsdX dsdA dsdA serB serB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yeaDPutative enzyme related to aldose 1-epimerase; Probably functions as a hexose-6-phosphate 1-epimerase. (294 aa)
ydcXPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74527.1); Blastp hit to AAC74527.1 (82 aa), 72% identity in aa 4 - 82. (87 aa)
sdaASimilar to E. coli L-serine deaminase (AAC74884.1); Blastp hit to AAC74884.1 (454 aa), 94% identity in aa 1 - 454; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa)
STM2196Putative D-serine dehydratase; Similar to E. coli L-serine deaminase (AAC74884.1); Blastp hit to AAC74884.1 (454 aa), 48% identity in aa 1 - 452; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa)
STM2361Putative regulatory protein; Similar to E. coli response regulator of ato, ornithine decarboxylase antizyme (sensor ATOS) (AAC75280.1); Blastp hit to AAC75280.1 (461 aa), 39% identity in aa 122 - 456. (475 aa)
sdaCPutative HAAAP family serine transport protein; Similar to E. coli probable serine transporter (AAC75838.1); Blastp hit to AAC75838.1 (429 aa), 95% identity in aa 1 - 429. (429 aa)
sdaBSimilar to E. coli L-serine dehydratase (deaminase), L-SD2 (AAC75839.1); Blastp hit to AAC75839.1 (455 aa), 94% identity in aa 1 - 455; L-threonine deaminase 2; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa)
yhaNPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76143.1); Blastp hit to AAC76143.1 (188 aa), 92% identity in aa 1 - 187; Belongs to the UPF0597 family. (436 aa)
yhaOSimilar to E. coli putative transport system permease protein (AAC76145.1); Blastp hit to AAC76145.1 (425 aa), 97% identity in aa 3 - 425. (443 aa)
tdcGSimilar to E. coli L-serine dehydratase (deaminase), L-SD2 (AAC75839.1); Blastp hit to AAC75839.1 (455 aa), 74% identity in aa 1 - 452; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa)
tdcCHAAAP family L-threonine/ L-serine permease; Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily. (443 aa)
tdcBThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. TdcB also dehydrates serine to yield pyruv [...] (329 aa)
tdcALysR family; similar to E. coli transcriptional activator of tdc operon (AAC76153.1); Blastp hit to AAC76153.1 (312 aa), 89% identity in aa 1 - 311; Belongs to the LysR transcriptional regulatory family. (312 aa)
yrdAPutative ferripyochelin binding protein; Similar to E. coli putative transferase (AAC76304.1); Blastp hit to AAC76304.1 (256 aa), 87% identity in aa 73 - 256. (184 aa)
STM3799Putative periplasmic protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (361 aa)
dsdCLysR family transcriptional activator; Similar to E. coli D-serine dehydratase (deaminase) transcriptional activator (AAC75423.1); Blastp hit to AAC75423.1 (311 aa), 90% identity in aa 1 - 307; Belongs to the LysR transcriptional regulatory family. (307 aa)
dsdXPutative Gnt family transport protein; Similar to E. coli transport system permease (serine?) (AAC75424.1); Blastp hit to AAC75424.1 (445 aa), 93% identity in aa 1 - 445. (445 aa)
dsdASimilar to E. coli D-serine dehydratase (deaminase) (AAC75425.1); Blastp hit to AAC75425.1 (442 aa), 89% identity in aa 1 - 442. (440 aa)
serBSimilar to E. coli 3-phosphoserine phosphatase (AAC77341.1); Blastp hit to AAC77341.1 (322 aa), 93% identity in aa 1 - 322. (322 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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