STRINGSTRING
aroP aroP aefA aefA ybiP ybiP STM0932 STM0932 ybjE ybjE ybjD ybjD phoH phoH ycdX ycdX ycdY ycdY ycdZ ycdZ ydeE ydeE tyrR tyrR tyrP tyrP yedE yedE yedF yedF STM1967 STM1967 mtr mtr bax bax ytfB ytfB fklB fklB trpR trpR
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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aroPAPC family aromatic amino acid transporter; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. (457 aa)
aefAPutative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117. (1120 aa)
ybiPPutative integral membrane protein; Similar to E. coli putative enzyme (AAC73902.1); Blastp hit to AAC73902.1 (527 aa), 84% identity in aa 1 - 526. (526 aa)
STM0932Similar to E. coli putative nucleotide di-P-sugar epimerase or dehydratase (AAC73955.1); Blastp hit to AAC73955.1 (349 aa), 93% identity in aa 13 - 349. (337 aa)
ybjESimilar to E. coli putative surface protein (AAC73961.1); Blastp hit to AAC73961.1 (315 aa), 88% identity in aa 17 - 315. (299 aa)
ybjDHomology with RecF protein; Similar to E. coli orf, hypothetical protein (AAC73963.1); Blastp hit to AAC73963.1 (552 aa), 89% identity in aa 1 - 552. (552 aa)
phoHSimilar to E. coli PhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation (AAC74105.1); Blastp hit to AAC74105.1 (354 aa), 92% identity in aa 71 - 354. (284 aa)
ycdXPutative Histidinol phosphatase; Related to hydrolases of the PHP family; similar to E. coli orf, hypothetical protein (AAC74118.1); Blastp hit to AAC74118.1 (245 aa), 89% identity in aa 1 - 245. (245 aa)
ycdYSimilar to E. coli putative oxidoreductase component (AAC74119.1); Blastp hit to AAC74119.1 (184 aa), 86% identity in aa 1 - 184. (184 aa)
ycdZPutative inner membrane protein; Hypothetical protein in phoH-csgG intergenic region. (SW:YCDZ_SALTY). (176 aa)
ydeESimilar to E. coli putative transport protein (AAC74607.1); Blastp hit to AAC74607.1 (395 aa), 76% identity in aa 1 - 395. (395 aa)
tyrRTranscriptional regulatory protein TyrR; Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalani [...] (513 aa)
tyrPHAAAP family tyrosine-specific transport protein; Similar to E. coli tyrosine-specific transport system (AAC74977.1); Blastp hit to AAC74977.1 (403 aa), 88% identity in aa 1 - 403. (403 aa)
yedEPutative membrane component of transport system; Hypothetical 44.2 Kda protein in amyA-fliE intergenic region. (SW:YEDE_SALTY). (421 aa)
yedFPutative transcriptional regulator; Hypothetical 8.6 Kda protein in amyA-fliE intergenic region (ORF 9). (SW:YEDF_ECOLI); Belongs to the sulfur carrier protein TusA family. (77 aa)
STM1967Putative 50S ribosomal protein. (128 aa)
mtrSimilar to E. coli tryptophan-specific transport protein (AAC76195.1); Blastp hit to AAC76195.1 (414 aa), 94% identity in aa 1 - 414. (414 aa)
baxGene transcribed divergently from malS; Similar to E. coli putative ATP-binding protein (AAC76594.1); Blastp hit to AAC76594.1 (274 aa), 89% identity in aa 1 - 274. (274 aa)
ytfBPutative cell envelope opacity-associated protein A; Similar to E. coli orf, hypothetical protein (AAC77163.1); Blastp hit to AAC77163.1 (224 aa), 85% identity in aa 13 - 224. (211 aa)
fklBSimilar to E. coli FKBP-type 22KD peptidyl-prolyl cis-trans isomerase (rotamase) (AAC77164.1); Blastp hit to AAC77164.1 (259 aa), 92% identity in aa 41 - 259. (220 aa)
trpRTranscriptional repressor for trp operon and aroH; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity). (108 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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