STRINGSTRING
ampE ampE yaiU yaiU STM0381 STM0381 aroM aroM ybaE ybaE STM0556 STM0556 STM0557 STM0557 apeE apeE fepE fepE ycaD ycaD ycaM ycaM yccR yccR mdoC mdoC mdoG mdoG mdoH mdoH ycfJ ycfJ mipA mipA STM1288 STM1288 ydjM ydjM STM1331 STM1331 rfc rfc ydiM ydiM ydcY ydcY srfA srfA srfB srfB srfC srfC ydcG ydcG STM1623 STM1623 STM1624 STM1624 ydbL ydbL ynbE ynbE ydbH ydbH ycjI ycjI yebS yebS STM1849 STM1849 yeeA yeeA asmA asmA STM2138 STM2138 setB setB yfaO yfaO STM2475 STM2475 ypfG ypfG yffH yffH sseB-2 sseB-2 STM2551 STM2551 STM2552 STM2552 csiE csiE ygaC ygaC iap iap STM3036 STM3036 STM3098 STM3098 yghW yghW yhbP yhbP nlp nlp yhdP yhdP bfr bfr bfd bfd yhfC yhfC STM3599 STM3599 yhjD yhjD yhjE yhjE yhjG yhjG yiaH yiaH yicH yicH fpr fpr yjbE yjbE yjbF yjbF yjbG yjbG yjbH yjbH yjbA yjbA ecnR ecnR yjfP yjfP yjgG yjgG yjgK yjgK mdoB mdoB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ampEPutative transmembrane protein; Similar to E. coli regulates ampC (AAC73222.1); Blastp hit to AAC73222.1 (284 aa), 84% identity in aa 1 - 284. (284 aa)
yaiUFlagellar protein; Similar to 3rd module of ATP-binding components of transporters; similar to E. coli putative flagellin structural protein (AAC73477.1); Blastp hit to AAC73477.1 (467 aa), 91% identity in aa 1 - 467. (978 aa)
STM0381Putative inner membrane protein. (237 aa)
aroMSimilar to E. coli protein of aro operon, regulated by aroR (AAC73493.1); Blastp hit to AAC73493.1 (225 aa), 77% identity in aa 1 - 225. (225 aa)
ybaEPutative ABC transporter periplasmic binding protein; Similar to E. coli orf, hypothetical protein (AAC73548.1); Blastp hit to AAC73548.1 (566 aa), 79% identity in aa 1 - 565. (566 aa)
STM0556Putative transposase. (72 aa)
STM0557Putative inner membrane protein. (550 aa)
apeEOuter membrane N-acetyl phenylalanine beta-naphthyl ester-cleaving esterase; Outer membrane esterase (gi|2896133). (656 aa)
fepESimilar to E. coli ferric enterobactin (enterochelin) transport (AAC73688.1); Blastp hit to AAC73688.1 (377 aa), 73% identity in aa 1 - 373. (378 aa)
ycaDPutative MFS family transport protein; Similar to E. coli putative transport (AAC73984.1); Blastp hit to AAC73984.1 (382 aa), 88% identity in aa 1 - 382. (382 aa)
ycaMPutative APC family, amino-acid transporter; Similar to E. coli putative transport (AAC73985.1); Blastp hit to AAC73985.1 (540 aa), 93% identity in aa 68 - 536. (473 aa)
yccRPutative DNA transformation protein; Similar to E. coli orf, hypothetical protein (AAC74045.1); Blastp hit to AAC74045.1 (209 aa), 75% identity in aa 1 - 199. (201 aa)
mdoCMembrane protein; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. (384 aa)
mdoGPeriplasmic glucans biosynthesis protein; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (511 aa)
mdoHMembrane glycosyltransferase; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (847 aa)
ycfJPutative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC74194.1); Blastp hit to AAC74194.1 (179 aa), 94% identity in aa 1 - 178. (179 aa)
mipAScaffolding protein for murein-synthesizing holoenzyme; Similar to E. coli orf, hypothetical protein (AAC74852.1); Blastp hit to AAC74852.1 (248 aa), 83% identity in aa 1 - 248. (248 aa)
STM1288Similar to E. coli putative an aldehyde reductase (AAC74851.1); Blastp hit to AAC74851.1 (284 aa), 78% identity in aa 4 - 284. (285 aa)
ydjMLexA regulated gene; Putative SOS response; similar to E. coli orf, hypothetical protein (AAC74798.1); Blastp hit to AAC74798.1 (200 aa), 86% identity in aa 1 - 199. (199 aa)
STM1331Putative inner membrane protein. (68 aa)
rfcO-antigen polymerase; May link the O-antigen tetrasaccharide units into long chains, giving rise to typical smooth LPS. (407 aa)
ydiMSimilar to E. coli putative transport system permease protein (AAC74760.1); Blastp hit to AAC74760.1 (404 aa), 79% identity in aa 1 - 395. (403 aa)
ydcYPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74528.1); Blastp hit to AAC74528.1 (77 aa), 85% identity in aa 1 - 77. (77 aa)
srfAssrAB activated gene; SrfA (gi|8347258). (439 aa)
srfBssrAB activated gene; SrfB (gi|8347259). (993 aa)
srfCssrAB activated gene; Predicted coiled-coil structure; SrfC (gi|8347260). (714 aa)
ydcGPutative periplasmic glucans biosynthesis protein; Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs); Belongs to the OpgD/OpgG family. (551 aa)
STM1623Putative carboxylesterase; Belongs to the type-B carboxylesterase/lipase family. (502 aa)
STM1624Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74505.1); Blastp hit to AAC74505.1 (447 aa), 87% identity in aa 1 - 447. (447 aa)
ydbLPutative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74465.1); Blastp hit to AAC74465.1 (110 aa), 70% identity in aa 3 - 109. (107 aa)
ynbEPutative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC74464.1); Blastp hit to AAC74464.1 (61 aa), 73% identity in aa 1 - 61. (63 aa)
ydbHPutative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74463.1); Blastp hit to AAC74463.1 (879 aa), 78% identity in aa 1 - 878. (878 aa)
ycjISimilar to E. coli putative carboxypeptidase (AAC74408.1); Blastp hit to AAC74408.1 (262 aa), 90% identity in aa 21 - 262. (242 aa)
yebSPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74903.1); Blastp hit to AAC74903.1 (427 aa), 85% identity in aa 1 - 427. (427 aa)
STM1849Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74904.1); Blastp hit to AAC74904.1 (879 aa), 90% identity in aa 1 - 879. (879 aa)
yeeAPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75069.1); Blastp hit to AAC75069.1 (352 aa), 79% identity in aa 1 - 352. (352 aa)
asmASimilar to E. coli suppressor of ompF assembly mutants (AAC75125.1); Blastp hit to AAC75125.1 (617 aa), 76% identity in aa 1 - 617. (618 aa)
STM2138Putative cytoplasmic protein. (138 aa)
setBProton efflux pump; Involved in the efflux of sugars. The physiological role may be the detoxification of non-metabolizable sugar analogs. Can transport lactose and glucose (By similarity); Belongs to the major facilitator superfamily. Set transporter family. (393 aa)
yfaOPutative NTP pyrophosphohydrolases including oxidative damage repair enzymes; Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP); Belongs to the Nudix hydrolase family. NudI subfamily. (141 aa)
STM2475Putative cytoplasmic protein. (76 aa)
ypfGPutative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75519.1); Blastp hit to AAC75519.1 (347 aa), 77% identity in aa 1 - 347. (347 aa)
yffHPutative pyrophosphohydrolase; Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP- mannose as its preferred substrate, yielding GMP and mannose-1- phosphate. (191 aa)
sseB-2Similar to E. coli enhanced serine sensitivity (AAC75575.1); Blastp hit to AAC75575.1 (261 aa), 90% identity in aa 1 - 261. (261 aa)
STM2551Putative inner membrane protein; Efflux system for nickel and cobalt. (328 aa)
STM2552Putative periplasmic or exported protein. (212 aa)
csiEStationary phase inducible protein; Similar to E. coli orf, hypothetical protein (AAC75588.1); Blastp hit to AAC75588.1 (433 aa), 71% identity in aa 8 - 432. (425 aa)
ygaCPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75718.1); Blastp hit to AAC75718.1 (114 aa), 88% identity in aa 1 - 112. (116 aa)
iapSimilar to E. coli alkaline phosphatase isozyme conversion, aminopeptidase (AAC75795.1); Blastp hit to AAC75795.1 (345 aa), 85% identity in aa 1 - 344. (348 aa)
STM3036Putative inner membrane protein. (268 aa)
STM3098Putative transcriptional regulator. (228 aa)
yghWPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76034.1); Blastp hit to AAC76034.1 (95 aa), 78% identity in aa 1 - 94. (95 aa)
yhbPPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76188.1); Blastp hit to AAC76188.1 (147 aa), 83% identity in aa 1 - 147; Belongs to the UPF0306 family. (147 aa)
nlpRegulatory factor of maltose metabolism; Similar to Ner repressor protein of phage Mu; similar to E. coli regulatory factor of maltose metabolism; similar to Ner repressor protein of phage Mu (AAC76220.1); Blastp hit to AAC76220.1 (92 aa), 86% identity in aa 1 - 92. (95 aa)
yhdPPutative protease; Similar to E. coli orf, hypothetical protein (AAC76277.1); Blastp hit to AAC76277.1 (986 aa), 80% identity in aa 1 - 986. (1266 aa)
bfrBacterioferrin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. (158 aa)
bfdRegulatory or redox component complexing with Bfr; Seems to associate with BFR; could be a general redox and/or regulatory component participating in the iron storage mobilization functions of BFR. Could participate in the release or the delivery of iron from/to bacterioferritin (or other iron complexes) (By similarity). (64 aa)
yhfCPutative MFS family transport protein; Similar to E. coli putative transport (AAC76389.1); Blastp hit to AAC76389.1 (393 aa), 90% identity in aa 1 - 393. (393 aa)
STM3599Putative inner membrane protein; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. (439 aa)
yhjDPutative tRNA-processing ribonuclease; Similar to E. coli orf, hypothetical protein (AAC76547.1); Blastp hit to AAC76547.1 (337 aa), 85% identity in aa 1 - 336. (342 aa)
yhjESimilar to E. coli putative transport protein (AAC76548.1); Blastp hit to AAC76548.1 (440 aa), 94% identity in aa 1 - 440. (440 aa)
yhjGPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76549.1); Blastp hit to AAC76549.1 (691 aa), 93% identity in aa 6 - 691. (686 aa)
yiaHPutative inner membrane protein; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units. (331 aa)
yicHPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76679.1); Blastp hit to AAC76679.1 (569 aa), 80% identity in aa 1 - 567. (569 aa)
fprSimilar to E. coli ferredoxin-NADP reductase (AAC76906.1); Blastp hit to AAC76906.1 (248 aa), 89% identity in aa 1 - 248. (248 aa)
yjbEPutative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC76996.1); Blastp hit to AAC76996.1 (80 aa), 96% identity in aa 1 - 80. (81 aa)
yjbFPutative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC76997.1); Blastp hit to AAC76997.1 (222 aa), 86% identity in aa 1 - 221. (222 aa)
yjbGPutative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76998.1); Blastp hit to AAC76998.1 (245 aa), 74% identity in aa 1 - 245. (245 aa)
yjbHPutative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC76999.1); Blastp hit to AAC76999.1 (698 aa), 92% identity in aa 1 - 698. (698 aa)
yjbAPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77000.1); Blastp hit to AAC77000.1 (136 aa), 87% identity in aa 1 - 136; Belongs to the PsiE family. (136 aa)
ecnRPutative luxR family bacterial regulatory protein. (195 aa)
yjfPPutative hydrolase of the alpha/beta superfamily; Similar to E. coli orf, hypothetical protein (AAC77147.1); Blastp hit to AAC77147.1 (249 aa), 71% identity in aa 1 - 249. (249 aa)
yjgGPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77204.1); Blastp hit to AAC77204.1 (110 aa), 56% identity in aa 1 - 41. (46 aa)
yjgKPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77209.1); Blastp hit to AAC77209.1 (153 aa), 80% identity in aa 4 - 153. (150 aa)
mdoBPhosphoglycerol transferase I; Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones; Belongs to the OpgB family. (750 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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