STRINGSTRING
wcaJ wcaJ wcaI wcaI wcaG wcaG gmd gmd wcaF wcaF wcaE wcaE wcaD wcaD wcaC wcaC wcaB wcaB wcaA wcaA wzc wzc wzb wzb wza wza
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
wcaJPutative UDP-glucose lipid carrier transferase; In colanic acid gene cluster; similar to E. coli putative colanic acid biosynthsis UDP-glucose lipid carrier transferase (AAC75108.1); Blastp hit to AAC75108.1 (464 aa), 89% identity in aa 1 - 464; glucose-1-phosphate transferase. (464 aa)
wcaIPutative glycosyl transferase; In colanic acid gene cluster; similar to E. coli putative colanic biosynthesis glycosyl transferase (AAC75111.1); Blastp hit to AAC75111.1 (407 aa), 85% identity in aa 1 - 407. (407 aa)
wcaGBifunctional GDP fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (321 aa)
gmdGDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (373 aa)
wcaFPutative acyltransferase; In colanic acid gene cluster; similar to E. coli putative transferase (AAC75115.1); Blastp hit to AAC75115.1 (182 aa), 87% identity in aa 1 - 180. (184 aa)
wcaEPutative transferase; In colanic acid gene cluster; similar to E. coli putative colanic acid biosynthesis glycosyl transferase (AAC75116.1); Blastp hit to AAC75116.1 (248 aa), 71% identity in aa 1 - 248. (248 aa)
wcaDSimilar to E. coli putative colanic acid polymerase (AAC75117.1); Blastp hit to AAC75117.1 (405 aa), 93% identity in aa 1 - 404. (404 aa)
wcaCPutative glycosyl transferase; In colanic acid gene cluster; similar to E. coli putative glycosyl transferase (AAC75118.1); Blastp hit to AAC75118.1 (405 aa), 80% identity in aa 1 - 405. (405 aa)
wcaBPutative acyl transferase; In colanic acid gene cluster; similar to E. coli putative transferase (AAC75119.1); Blastp hit to AAC75119.1 (162 aa), 91% identity in aa 1 - 160; Belongs to the transferase hexapeptide repeat family. (162 aa)
wcaAPutative glycosyl transferase; In colanic acid gene cluster; similar to E. coli putative regulator (AAC75120.1); Blastp hit to AAC75120.1 (279 aa), 91% identity in aa 3 - 279. (280 aa)
wzcPutative tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium (By similarity). Belongs to the etk/wzc family. (719 aa)
wzbPutative protein-tyrosine-phosphatase; Dephosphorylates Wzc. Required for the extracellular polysaccharide colanic acid synthesis. Probably involved in the export of colanic acid from the cell to medium. Involved in protection of cells against contact-dependent growth inhibition (CDI). (149 aa)
wzaPutative polysaccharide export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. (379 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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