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| | glnD | Uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (890 aa) |
| | rcsF | Regulator in colanic acid synthesis; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family. (134 aa) |
| | yaiC | Putative diguanylate cyclase/phosphodiesterase domain 1; Similar to E. coli orf, hypothetical protein (AAC73488.1); Blastp hit to AAC73488.1 (371 aa), 75% identity in aa 1 - 371. (370 aa) |
| | glnK | Regulatory protein P-II 2; Nitrogen assimilation by glutamine synthetase; regulates GlnL (NRII) and GlnE (ATase); similar to E. coli nitrogen regulatory protein P-II 2 (AAC73553.1); Blastp hit to AAC73553.1 (112 aa), 97% identity in aa 1 - 112. (112 aa) |
| | amtB | Putative Amt family, ammonium transport protein; Similar to E. coli probable ammonium transporter (AAC73554.1); Blastp hit to AAC73554.1 (428 aa), 92% identity in aa 1 - 428. (428 aa) |
| | ylaB | Putative diguanylate cyclase/phosphodiesterase domain 2; Similar to E. coli orf, hypothetical protein (AAC73559.1); Blastp hit to AAC73559.1 (518 aa), 67% identity in aa 3 - 518. (516 aa) |
| | STM0561 | Sensor protein; Similar to E. coli putative 2-component sensor protein (AAC73671.1); Blastp hit to AAC73671.1 (480 aa), 74% identity in aa 375 - 479. (109 aa) |
| | flgN | Flagellar biosynthesis protein; Required for the efficient initiation of filament assembly. (140 aa) |
| | flgM | anti-FliA factor; Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA; Belongs to the FlgM family. (97 aa) |
| | flgA | Flagellar biosynthesis protein; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (219 aa) |
| | flgB | Flagellar biosynthesis protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body. (138 aa) |
| | flgC | Flagellar biosynthesis protein; Cell-proximal portion of basal-body rod; flagellar basal-body rod protein FLGC (putative proximal rod protein). (SW:FLGC_SALTY); Belongs to the flagella basal body rod proteins family. (134 aa) |
| | flgD | Flagellar biosynthesis protein; Required for flagellar hook formation. May act as a scaffolding protein; Belongs to the FlgD family. (232 aa) |
| | flgE | Hook protein; Flagellar biosynthesis; flagellar hook protein flge. (SW:FLGE_SALTY); Belongs to the flagella basal body rod proteins family. (403 aa) |
| | flgF | Flagellar biosynthesis protein; Cell-proximal portion of basal-body rod; flagellar basal-body rod protein flgf (putative proximal rod protein). (SW:FLGF_SALTY); Belongs to the flagella basal body rod proteins family. (251 aa) |
| | flgG | Flagellar biosynthesis protein; Cell-distal portion of basal-body rod; flagellar basal-body rod protein flgg (distal rod protein). (SW:FLGG_SALTY); Belongs to the flagella basal body rod proteins family. (260 aa) |
| | flgH | Flagellar biosynthesis protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. (232 aa) |
| | flgI | Putative flagella basal body protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. (365 aa) |
| | flgJ | Flagellar biosynthesis protein; Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; In the C-terminal section; belongs to the glycosyl hydrolase 73 family. (316 aa) |
| | flgK | Hook-filament junction protein 1; Flagellar biosynthesis protein; flagellar hook-associated protein 1 (HAP1). (SW:FLGK_SALTY); Belongs to the flagella basal body rod proteins family. (553 aa) |
| | flgL | Hook-filament junction protein; Flagellar biosynthesis protein; flagellar hook-associated protein 3 (HAP3) (hook-filament junctionprotein). (SW:FLGL_SALTY). (317 aa) |
| | yeaJ | Putative methyl-accepting chemotaxis protein; Diguanylate cyclase/phosphodiesterase domain 1; similar to E. coli orf, hypothetical protein (AAC74856.1); Blastp hit to AAC74856.1 (556 aa), 68% identity in aa 61 - 556. (497 aa) |
| | ydiV | Putative diguanylate cyclase/phosphodiesterase domain 1; Acts as an anti-FlhC(2)FlhD(4) factor by binding to FlhD, decreasing its ability to bind DNA, and thus negatively regulates expression of flagellar class II operons, decreasing motility in nutrient-poor medium. Required for resistance to host phagocyte oxidase. Suppresses killing of macrophages, while promoting resistance to hydrogen peroxide. Data regarding c-di-GMP is controversial; suppresses bacterial c-di-GMP levels but neither synthesizes nor degrades c-di-GMP. Belongs to the YdiV family. (237 aa) |
| | ssrB | Secretion system regulator: transcriptonal activator; Homologous with degU/uvrY/bvgA; SsrB (gi|2765824). (212 aa) |
| | ssrA | Secretion system regulator: Sensor component; SpiR (gi|1498305). (920 aa) |
| | rstB | Sensory histidine kinase in two-component regulatory system with RstA; Similar to E. coli sensor histidine protein kinase (RstA regulator) (AAC74681.1); Blastp hit to AAC74681.1 (433 aa), 82% identity in aa 1 - 433. (433 aa) |
| | rstA | Similar to E. coli response transcriptional regulatory protein (RstB sensor) (AAC74680.1); Blastp hit to AAC74680.1 (242 aa), 84% identity in aa 4 - 242. (243 aa) |
| | STM1484 | Putative protease; Similar to E. coli orf, hypothetical protein (AAC74670.1); Blastp hit to AAC74670.1 (273 aa), 77% identity in aa 1 - 272; Belongs to the peptidase S1B family. (273 aa) |
| | trg | Methyl-accepting chemotaxis protein III; Ribose and galactose sensor receptor; similar to E. coli methyl-accepting chemotaxis protein III, ribose sensor receptor (AAC74503.1); Blastp hit to AAC74503.1 (546 aa), 79% identity in aa 6 - 526. (541 aa) |
| | STM1657 | Similar to E. coli methyl-accepting chemotaxis protein I, serine sensor receptor (AAC77311.1); Blastp hit to AAC77311.1 (551 aa), 39% identity in aa 195 - 519. (384 aa) |
| | pspF | Similar to E. coli psp operon transcriptional activator (AAC74385.1); Blastp hit to AAC74385.1 (330 aa), 86% identity in aa 6 - 330. (326 aa) |
| | STM1697 | Putative diguanylate cyclase/phosphodiesterase domain 2; Similar to E. coli orf, hypothetical protein (AAC74777.1); Blastp hit to AAC74777.1 (237 aa), 29% identity in aa 17 - 189. (198 aa) |
| | yciR | Putative PAS/PAC domain protein; Diguanylate cyclase/phosphodiesterase domain 1; Diguanylate cyclase/phosphodiesterase domain 2; similar to E. coli orf, hypothetical protein (AAC74367.1); Blastp hit to AAC74367.1 (661 aa), 79% identity in aa 1 - 657. (660 aa) |
| | ycgR | Putative inner membrane protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Overexpression of this gene decreases swimming and swarming motility; those cells that are motile turn predominantly counterclockwise. The D- 118 mutant is still able to bind FliM but no longer affects motility upon overexpression. Binds 1 c-di-GMP dimer per subunit. (244 aa) |
| | STM1827 | Putative diguanylate cyclase/phosphodiesterase; Similar to E. coli orf, hypothetical protein (AAC74885.1); Blastp hit to AAC74885.1 (542 aa), 75% identity in aa 5 - 540. (567 aa) |
| | flhE | Flagellar protein; Not essential for flagellar formation and function. (130 aa) |
| | flhA | Flagellar biosynthesis protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. (692 aa) |
| | flhB | Putative part of export apparatus for flagellar proteins; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (383 aa) |
| | cheZ | Chemotactic response protein; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). Acts on free CheY-P. Belongs to the CheZ family. (214 aa) |
| | cheY | Chemotaxis regulator protein; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Shows autophosphatase activity which is enhanced by CheZ. (129 aa) |
| | cheB | Methyl esterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid (By similarity). Belongs to the CheB family. (349 aa) |
| | cheR | Glutamate methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (288 aa) |
| | cheM | Methyl accepting chemotaxis protein II; Receptor for the attractant L-aspartate and related amino and dicarboxylic acids. Tar mediates taxis away from the repellents cobalt and nickel. Unlike in E.coli tar, it does not mediates maltose taxis. (553 aa) |
| | cheW | Purine-binding chemotaxis protein; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. (167 aa) |
| | cheA | Sensory histitine protein kinase; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY. (671 aa) |
| | motB | Enables flagellar motor rotation; MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque-generating machinery to the cell wall (By similarity). (309 aa) |
| | motA | Proton conductor component of motor; MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity). (295 aa) |
| | flhC | Regulator of flagellar biosynthesis; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (Probable); Belongs to the FlhC family. (194 aa) |
| | flhD | Regulator of flagellar biosynthesis; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (Probable); Belongs to the FlhD family. (116 aa) |
| | uvrY | Putative LuxR/UhpA family response regulator; Similar to E. coli putative 2-component transcriptional regulator (AAC74981.1); Blastp hit to AAC74981.1 (218 aa), 96% identity in aa 1 - 218. (218 aa) |
| | fliZ | Putative regulator of FliA; May regulate sigma factor activity. (183 aa) |
| | fliA | Sigma F (sigma 28) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. May regulate the expression of genes involved in virulence. (239 aa) |
| | fliC | Flagellar biosynthesis; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (495 aa) |
| | fliD | Filament capping protein; Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end; Belongs to the FliD family. (467 aa) |
| | fliS | Repressor of class 3a and 3b operons (RflA activity); Flagellar biosynthesis; flagellar protein FLIS. (SW:FLIS_SALTY); Belongs to the FliS family. (135 aa) |
| | fliT | Possible export chaperone for FliD; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus. Belongs to the FliT family. (122 aa) |
| | fliE | Flagellar hook-basal body complex protein FLIE. (SW:FLIE_SALTY). (104 aa) |
| | fliF | Basal-body MS (membrane and supramembrane)-ring and collar protein; The M ring may be actively involved in energy transduction. (560 aa) |
| | fliG | Flagellar biosynthesis protein; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity). (331 aa) |
| | fliH | Flagellar biosynthesis protein; Needed for flagellar regrowth and assembly. (235 aa) |
| | fliI | Flagellum-specific ATP synthase; Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage; Belongs to the ATPase alpha/beta chains family. (456 aa) |
| | fliJ | Flagellar FliJ protein; Flagellar protein that affects chemotactic events. (147 aa) |
| | fliK | Flagellar hook-length control protein; Controls the length of the flagellar hook. (405 aa) |
| | fliL | Flagellar biosynthesis; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. (155 aa) |
| | fliM | Flagellar biosynthesis protein; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity). (334 aa) |
| | fliN | Flagellar biosynthesis protein; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity). Belongs to the FliN/MopA/SpaO family. (137 aa) |
| | fliO | Flagellar protein FLIO. (SW:FLIO_SALTY). (125 aa) |
| | fliP | Flagellar biosynthesis protein; Plays a role in the flagellum-specific transport system. (245 aa) |
| | fliQ | Flagellar biosynthesis protein; Required for the assembly of the rivet at the earliest stage of flagellar biosynthesis; Belongs to the FliQ/MopD/SpaQ family. (89 aa) |
| | fliR | Putative flagellar biosynthetic protein; Role in flagellar biosynthesis; Belongs to the FliR/MopE/SpaR family. (264 aa) |
| | rcsA | Positive transcriptional regulator of capsular/exo- polysaccharide synthesis (LuxR/UhpA family); Component of the Rcs signaling system, which controls transcription of numerous genes. Binds, with RcsB, to the RcsAB box to regulate expression of genes. (207 aa) |
| | dgcQ | Putative inner membrane protein; Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (By similarity). Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria. Involved in the regulation of cellulose production (By similarity). (570 aa) |
| | yegE | Putative PAS/PAC domain protein; Diguanylate cyclase/phosphodiesterase domain 1 and Diguanylate cyclase/phosphodiesterase domain 2 containing; similar to E. coli putative sensor-type protein (AAC75128.1); Blastp hit to AAC75128.1 (1105 aa), 76% identity in aa 540 - 437. (996 aa) |
| | rtn | Putative membrane protein involved in resistance to lambda and N4 phages; Similar to E. coli orf, hypothetical protein (AAC75237.1); Blastp hit to AAC75237.1 (518 aa), 70% identity in aa 1 - 518. (518 aa) |
| | yojN | Putative sensor/kinase in regulatory system; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (889 aa) |
| | rcsB | LuxR/UhpA family response regulator in two-component regulatory system with RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. Can function both in an RcsA-dependent or RcsA-independent manner. (216 aa) |
| | rcsC | Sensory histidine kinase in two-component regulatory system with RcsB; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (948 aa) |
| | STM2314 | Putative chemotaxis signal transduction protein; Similar to E. coli positive regulator of CheA protein activity (AAC74957.1); Blastp hit to AAC74957.1 (167 aa), 25% identity in aa 18 - 151. (333 aa) |
| | flk | Cell division protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion (T3S) system. Plays a role in hindering to flip the flagellar T3S specificity switch from the rod and hook-type substrates to filament-type substrates prior to hook-basal body (HBB) completion possibly by preventing interaction of FliK with FlhB. (333 aa) |
| | yfeA | Diguanylate cyclase/phosphodiesterase domain 2; similar to E. coli orf, hypothetical protein (AAC75454.1); Blastp hit to AAC75454.1 (768 aa), 68% identity in aa 45 - 766. (729 aa) |
| | STM2503 | Putative diguanylate cyclase; Similar to E. coli putative cytochrome C-type biogenesis protein (AAC75556.1); Blastp hit to AAC75556.1 (747 aa), 73% identity in aa 1 - 733. (737 aa) |
| | glnB | Regulatory protein (P-II) for nitrogen assimilation by glutamine synthetase (ATase); P-II indirectly controls the transcription of the glutamine synthetase gene (GlnA). P-II prevents NR-II-catalyzed conversion of NR- I to NR-I-phosphate, the transcriptional activator of GlnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase by GlnE, so activating the enzyme (By similarity). (112 aa) |
| | yfhA | EBP family; similar to E. coli putative 2-component transcriptional regulator (AAC75607.1); Blastp hit to AAC75607.1 (444 aa), 95% identity in aa 1 - 444. (445 aa) |
| | yfhG | Putative transcriptional regulator of two-component regulator protein (EBP familiiy); EBP family; similar to E. coli putative alpha helix protein (AAC75608.1); Blastp hit to AAC75608.1 (237 aa), 63% identity in aa 1 - 234. (254 aa) |
| | yfhK | Putative sensory kinase in regulatory system; Similar to E. coli putative 2-component sensor protein (AAC75609.1); Blastp hit to AAC75609.1 (496 aa), 87% identity in aa 19 - 496. (480 aa) |
| | yfiR | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75652.1); Blastp hit to AAC75652.1 (172 aa), 66% identity in aa 1 - 169. (172 aa) |
| | yfiN | Putative diguanylate cyclase/phosphodiesterase; Similar to E. coli orf, hypothetical protein (AAC75653.1); Blastp hit to AAC75653.1 (408 aa), 75% identity in aa 2 - 405. (406 aa) |
| | csrA | Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (61 aa) |
| | fhlA | Formate hydrogen-lyase transcriptional activator for fdhF, hyc and hyp operons; Required for induction of expression of the formate dehydrogenase H and hydrogenase-3 structural genes. (692 aa) |
| | barA | Sensory histidine kinase; Similar to E. coli sensor-regulator, activates OmpR by phophorylation (AAC75828.1); Blastp hit to AAC75828.1 (918 aa), 90% identity in aa 1 - 918. (918 aa) |
| | STM3152 | Similar to E. coli methyl-accepting chemotaxis protein I, serine sensor receptor (AAC77311.1); Blastp hit to AAC77311.1 (551 aa), 43% identity in aa 1 - 551. (547 aa) |
| | aer | Aerotaxis sensor receptor; Senses cellular redox state or proton motive force; similar to E. coli aerotaxis sensor receptor, flavoprotein (AAC76107.1); Blastp hit to AAC76107.1 (506 aa), 83% identity in aa 1 - 506. (506 aa) |
| | rpoN | Sigma N factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of enzymes involved in arginine catabolism. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for the receipt of the melting signal from the remotely bound activator protein GlnG(NtrC). (477 aa) |
| | arcB | Sensory histidine kinase in two-component regulatory system with ArcA; Senses redox conditions; similar to E. coli aerobic respiration sensor-response protein; histidine protein kinase/phosphatase, sensor for arcA (AAC76242.1); Blastp hit to AAC76242.1 (776 aa), 93% identity in aa 1 - 776. (778 aa) |
| | yhdA | Putative diguanylate cyclase; Similar to E. coli orf, hypothetical protein (AAC76284.1); Blastp hit to AAC76284.1 (646 aa), 84% identity in aa 1 - 646. (646 aa) |
| | STM3388 | Putative membrane domain protein involved in signal transduction; Diguanylate cyclase/phosphodiesterase domain 1; Diguanylate cyclase/phosphodiesterase domain 2; similar to E. coli orf, hypothetical protein (AAC74367.1); Blastp hit to AAC74367.1 (661 aa), 37% identity in aa 228 - 652, 39% identity in aa 144 - 171. (699 aa) |
| | yhfA | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76381.1); Blastp hit to AAC76381.1 (134 aa), 94% identity in aa 1 - 134. (134 aa) |
| | yhfK | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76383.1); Blastp hit to AAC76383.1 (696 aa), 86% identity in aa 1 - 695. (695 aa) |
| | yrfF | Putative inner membrane protein; Involved in negative control of bacterial proliferation within fibroblasts; Belongs to the IgaA family. (710 aa) |
| | envZ | Sensory histidine kinase in two-component regulatory system with OmpR; Member of the two-component regulatory system EnvZ/OmpR involved in osmoregulation (particularly of genes ompF and ompC) as well as other genes (By similarity). EnvZ functions as a membrane- associated protein kinase that phosphorylates OmpR in response to environmental signals; at low osmolarity OmpR activates ompF transcription, while at high osmolarity it represses ompF and activates ompC transcription (By similarity). (450 aa) |
| | ompR | Response regulator in two-component regulatory system with EnvZ; Member of the two-component regulatory system EnvZ/OmpR involved in osmoregulation (particularly of genes ompF and ompC) as well as other genes (By similarity). Plays a central role in both acid and osmotic stress responses. Binds to the promoter of both ompC and ompF; at low osmolarity it activates ompF transcription, while at high osmolarity it represses ompF and activates ompC transcription (By similarity). (239 aa) |
| | tcp | Methyl-accepting transmembrane citrate/phenol chemoreceptor; Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes. (547 aa) |
| | yhjH | Putative diguanylate cyclase/phosphodiesterase domain 3 containing protein; Similar to E. coli orf, hypothetical protein (AAC76550.1); Blastp hit to AAC76550.1 (256 aa), 79% identity in aa 2 - 256. (255 aa) |
| | yhjK | Putative diguanylate cyclase/phosphodiesterase; Similar to E. coli orf, hypothetical protein (AAC76554.1); Blastp hit to AAC76554.1 (651 aa), 84% identity in aa 1 - 651. (657 aa) |
| | glnG | EBP family response regulator in two-component regulatory system with GlnL; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (469 aa) |
| | glnL | Sensory histidine kinase/phosphatase NtrB; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Under conditions of nitrogen limitation, NtrB autophosphorylates and transfers the phosphoryl group to NtrC. In the presence of nitrogen, acts as a phosphatase that dephosphorylates and inactivates NtrC. (349 aa) |
| | cpxA | Sensory kinase in two-component regulatory system with CpxR; Senses misfolded proteins in bacterial envelope; similar to E. coli probable sensor protein (histidine protein kinase), acting on arcA (AAC76893.1); Blastp hit to AAC76893.1 (457 aa), 96% identity in aa 1 - 457. (457 aa) |
| | cpxR | Response reguator in two-component regulatory system with CpxA; Regulates expression of protein folding and degrading factors (OmpR family); similar to E. coli transcriptional regulator in 2-component system (AAC76894.1); Blastp hit to AAC76894.1 (232 aa), 97% identity in aa 1 - 232. (232 aa) |
| | cpxP | Periplasmic repressor of cpx regulon by interaction with CpxA; Rescue from transitory stresses; similar to E. coli orf, hypothetical protein (AAC76896.1); Blastp hit to AAC76896.1 (122 aa), 94% identity in aa 1 - 122. (166 aa) |
| | zraP | Zinc-resistance associated protein; Binds zinc. Could be an important component of the zinc- balancing mechanism (By similarity); Belongs to the ZraP family. (151 aa) |
| | hydH | Sensory kinase in two component regulatory system with HydG; Member of the two-component regulatory system ZraS/ZraR. May function as a membrane-associated protein kinase that phosphorylates ZraR in response to high concentrations of zinc or lead in the medium (By similarity). (465 aa) |
| | hydG | Response regulator in two-component reguatory system with HydH; Member of the two-component regulatory system ZraS/ZraR. When activated by ZraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon (By similarity). (441 aa) |
| | yjcC | Putative diguanylate cyclase/phosphodiesterase; Similar to E. coli orf, hypothetical protein (AAC77031.1); Blastp hit to AAC77031.1 (528 aa), 64% identity in aa 1 - 528. (533 aa) |
| | tsr | Serine sensor receptor; similar to E. coli methyl-accepting chemotaxis protein I, serine sensor receptor (AAC77311.1); Blastp hit to AAC77311.1 (551 aa), 86% identity in aa 1 - 551. (553 aa) |
| | STM4551 | Putative diguanylate cyclase/phosphodiesterase domain 1 containing protein; Similar to E. coli orf, hypothetical protein (AAC74110.1); Blastp hit to AAC74110.1 (452 aa), 41% identity in aa 274 - 444, 24% identity in aa 14 - 102. (354 aa) |
| | creA | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77350.1); Blastp hit to AAC77350.1 (157 aa), 89% identity in aa 1 - 157. (157 aa) |
| | creB | Response regulator in two-component regulatory system with CreC; OmpR family; similar to E. coli catabolic regulation response regulator (AAC77351.1); Blastp hit to AAC77351.1 (229 aa), 83% identity in aa 1 - 229. (229 aa) |
| | creC | Sensory kinase (alternative) in two-component regulatory system with CreB (or alternatively PhoB); Senses catabolite repression; similar to E. coli catabolite repression sensor kinase for PhoB; alternative sensor for pho regulon (AAC77352.1); Blastp hit to AAC77352.1 (474 aa), 80% identity in aa 1 - 474. (474 aa) |
| | creD | Similar to E. coli tolerance to colicin E2 (AAC77353.1); Blastp hit to AAC77353.1 (450 aa), 73% identity in aa 1 - 450. (449 aa) |
| | arcA | Response regulator (OmpR family) in two-component regulatory system with ArcB (or CpxA); Regulates genes in aerobic pathways; similar to E. coli negative response regulator of genes in aerobic pathways, (sensors, ArcB and CpxA) (AAC77354.1); Blastp hit to AAC77354.1 (238 aa), 99% identity in aa 1 - 238. (238 aa) |
