STRINGSTRING
STM0041 STM0041 STM0042 STM0042 araD araD araA araA araB araB araC araC fruR fruR STM0148 STM0148 STM0149 STM0149 pfs pfs STM0563 STM0563 STM0581 STM0581 ybjX ybjX lrp lrp STM1251 STM1251 ydiP ydiP purR purR STM1472 STM1472 ynfL ynfL STM1541 STM1541 STM1555 STM1555 STM1556 STM1556 STM1573 STM1573 cybB cybB STM1671 STM1671 mglC mglC mglA mglA mglB mglB galS galS STM2195 STM2195 STM2197 STM2197 STM2198 STM2198 bcr bcr STM2275 STM2275 rhmA rhmA STM2345 STM2345 pgtA pgtA pgtB pgtB pgtC pgtC pgtP pgtP hcaT hcaT luxS luxS fucO fucO fucA fucA fucI fucI fucK fucK fucU fucU fucR fucR galR galR STM3012 STM3012 ygeA ygeA araE araE STM3020 STM3020 STM3084 STM3084 STM3357 STM3357 STM3358 STM3358 yhdV yhdV crp crp gntT gntT gntU gntU gntK gntK rbsK-2 rbsK-2 STM3602 STM3602 yhjB yhjB STM3633 STM3633 xylB xylB xylA xylA xylR xylR avtA avtA STM3678 STM3678 STM3679 STM3679 yicI yicI STM3780 STM3780 STM3781 STM3781 STM3785 STM3785 yicN yicN uhpT uhpT uhpC uhpC uhpB uhpB uhpA uhpA STM3791 STM3791 STM3792 STM3792 STM3794 STM3794 rbsD rbsD rbsA rbsA rbsC rbsC rbsB rbsB rbsK rbsK rbsR rbsR yieP yieP cyaA cyaA STMD1.48 STMD1.48 yiiL yiiL rhaD rhaD rhaA rhaA rhaB rhaB rhaS rhaS rhaR rhaR rhaT rhaT STM4065 STM4065 STM4066 STM4066 STM4067 STM4067 STM4068 STM4068 STM4071 STM4071 ydeV ydeV ydeW ydeW ego ego ydeY ydeY ydeZ ydeZ yneA yneA yneB yneB yneC yneC cytR cytR yijO yijO melR melR yjeJ yjeJ treR treR idnR idnR idnT idnT idnO idnO idnD idnD idnK idnK STM4502 STM4502 uxuR uxuR rob rob
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STM0041Putative glycosyl hydrolase; Similar to E. coli orf, hypothetical protein (AAC76680.1); Blastp hit to AAC76680.1 (772 aa), 25% identity in aa 116 - 547, 27% identity in aa 549 - 665, 25% identity in aa 84 - 149; Belongs to the glycosyl hydrolase 31 family. (679 aa)
STM0042Putative sodium galactoside symporter; Similar to E. coli putative permease (AAC76681.1); Blastp hit to AAC76681.1 (479 aa), 29% identity in aa 22 - 457. (457 aa)
araDL-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5- phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction). (231 aa)
araAL-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (500 aa)
araBL-ribulokinase. (SW:KIRI_SALTY). (569 aa)
araCTranscriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. (281 aa)
fruRTranscriptional repressor of fru operon and others; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. (334 aa)
STM0148Putative cytoplasmic protein; Hypothetical protein (gi|7688348); Belongs to the glycosyl hydrolase 43 family. (316 aa)
STM0149Putative permease of the Na+:galactoside symporter family; Hypothetical protein (gi|7688349). (468 aa)
pfs5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulatio [...] (232 aa)
STM0563Putative transcriptional regulator (AraC/XylS family); Similar to E. coli putative ARAC-type regulatory protein (AAC73408.1); Blastp hit to AAC73408.1 (284 aa), 71% identity in aa 1 - 282. (284 aa)
STM0581Putative regulatory protein; Resistance against oxidative stress protein A (gi|9885772). (113 aa)
ybjXHomolog of virK; Similar to E. coli putative enzyme (AAC73964.1); Blastp hit to AAC73964.1 (330 aa), 57% identity in aa 15 - 329. (322 aa)
lrpRegulator for lrp regulon and high-affinity branched-chain amino acid transport system; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes. (164 aa)
STM1251Putative molecular chaperone (small heat shock protein); Similar to E. coli heat shock protein (AAC76710.1); Blastp hit to AAC76710.1 (137 aa), 33% identity in aa 1 - 136; Belongs to the small heat shock protein (HSP20) family. (155 aa)
ydiPPutative transcription regulator, AraC family; Similar to E. coli putative ARAC-type regulatory protein (AAC74766.1); Blastp hit to AAC74766.1 (303 aa), 80% identity in aa 1 - 292. (296 aa)
purRTranscriptional repressor for pur regulon, glyA, glnB, prsA, speA (GalR/LacI family); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. (341 aa)
STM1472Putative periplasmic protein. (568 aa)
ynfLSimilar to E. coli putative transcriptional regulator LYSR-type (AAC74667.1); Blastp hit to AAC74667.1 (297 aa), 83% identity in aa 1 - 297; Belongs to the LysR transcriptional regulatory family. (299 aa)
STM1541Putative gntR family regulatory protein; Similar to E. coli regulator for uxu operon (AAC77280.1); Blastp hit to AAC77280.1 (257 aa), 31% identity in aa 8 - 229. (263 aa)
STM1555Putative transcriptional regulator; Similar to E. coli repressor of galETK operon (AAC75876.1); Blastp hit to AAC75876.1 (343 aa), 42% identity in aa 1 - 330. (335 aa)
STM1556Putative Na+/H+ antiporter; Similar to E. coli transport of dicarboxylates (AAC73722.1); Blastp hit to AAC73722.1 (461 aa), 23% identity in aa 36 - 414. (483 aa)
STM1573Putative cytoplasmic protein. (126 aa)
cybBSimilar to E. coli cytochrome b(561) (AAC74500.1); Blastp hit to AAC74500.1 (188 aa), 84% identity in aa 13 - 187. (176 aa)
STM1671Putative bacterial regulatory helix-turn-helix protein, araC family; Similar to E. coli putative ARAC-type regulatory protein (AAC73403.1); Blastp hit to AAC73403.1 (239 aa), 35% identity in aa 12 - 210. (285 aa)
mglCMethyl-galactoside transport protein; Part of the binding-protein-dependent transport system for galactoside. Probably responsible for the translocation of the substrate across the membrane. (336 aa)
mglAGalactose (methyl-galactoside) transport protein; Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system (Probable). (506 aa)
mglBGalactose transport protein; This protein is involved in the active transport of galactose and glucose. It plays a role in the chemotaxis towards the two sugars by interacting with the trg chemoreceptor. (332 aa)
galSGalR/LacI family transcriptional repressor of mgl operon; Repressor of the mgl operon. Binds galactose and D-fucose as inducers. GalS binds to an operator DNA sequence within its own coding sequence (By similarity). (340 aa)
STM2195Putative transcriptional regulator. (129 aa)
STM2197Similar to E. coli 3-phosphoserine phosphatase (AAC77341.1); Blastp hit to AAC77341.1 (322 aa), 39% identity in aa 111 - 305. (295 aa)
STM2198Putative regulatory protein; Similar to E. coli regulator of uhpT (AAC76690.1); Blastp hit to AAC76690.1 (440 aa), 39% identity in aa 5 - 428. (440 aa)
bcrBicyclomycin resistance protein; MFS family multidrug transport protein; similar to E. coli bicyclomycin resistance protein; transmembrane protein (AAC75243.1); Blastp hit to AAC75243.1 (396 aa), 93% identity in aa 1 - 396. (396 aa)
STM2275Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC74613.1); Blastp hit to AAC74613.1 (228 aa), 25% identity in aa 13 - 217. (294 aa)
rhmAPutative 2,4-dihydoxyhept-2-ene-1,7-dioic acid aldolase; Catalyzes the reversible retro-aldol cleavage of 2-keto-3- deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde. Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily. (267 aa)
STM2345Putative transcriptional regulator; Similar to E. coli regulator of gluconate (gnt) operon (AAC76463.1); Blastp hit to AAC76463.1 (313 aa), 37% identity in aa 8 - 299. (339 aa)
pgtAActivator protein; Member of the two-component regulatory system PgtB/PgtA that regulates the inducible phosphoglycerate transport system. When activated by PgtB it acts in conjunction with sigma-54 as a transcriptional activator. (415 aa)
pgtBProtein for signal transmission; Member of the two-component regulatory system PgtB/PgtA that regulates the inducible phosphoglycerate transport system. Activates PgtA by phosphorylation. (668 aa)
pgtCProtein for signal transmission; Required for PgtP expression, it may act jointly with the PgtA/PgtB signaling proteins. (397 aa)
pgtPTransporter protein; The phosphoglycerate transporter protein is a part of the PGT transport system. It is the membrane bound transporter for phosphoglycerate into salmonella. (463 aa)
hcaTSimilar to E. coli MFS (major facilitator superfamily) transporter (AAC75589.1); Blastp hit to AAC75589.1 (379 aa), 88% identity in aa 1 - 376. (379 aa)
luxSQuorum sensing protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD) (By similarity); Belongs to the LuxS family. (171 aa)
fucOSimilar to E. coli L-1,2-propanediol oxidoreductase (AAC75841.1); Blastp hit to AAC75841.1 (383 aa), 91% identity in aa 2 - 383. (382 aa)
fucAL-fuculose-1-phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. (215 aa)
fucIL-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose. (591 aa)
fucKL-fuculokinase; Catalyzes the phosphorylation of L-fuculose. Belongs to the FGGY kinase family. (472 aa)
fucUConserved protein of fucose operon; Involved in the anomeric conversion of L-fucose. (140 aa)
fucRDeoR family; similar to E. coli positive regulator of the fuc operon (AAC75847.1); Blastp hit to AAC75847.1 (243 aa), 88% identity in aa 1 - 235. (236 aa)
galRTranscriptional repressor of galETK operon; Repressor of the galactose operon. Binds galactose as an inducer (By similarity). (342 aa)
STM3012Putative transcriptional regulator; Similar to E. coli ascBF operon repressor (AAC75756.1); Blastp hit to AAC75756.1 (337 aa), 41% identity in aa 1 - 334. (340 aa)
ygeAPutative aspartate racemase; Similar to E. coli putative resistance proteins (AAC75879.1); Blastp hit to AAC75879.1 (230 aa), 79% identity in aa 1 - 230; Belongs to the aspartate/glutamate racemases family. (235 aa)
araEL-arabinose: proton symport protein; Low-affinity transporter;MFS family; similar to E. coli low-affinity L-arabinose transport system proton symport protein (AAC75880.1); Blastp hit to AAC75880.1 (472 aa), 97% identity in aa 1 - 472; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (472 aa)
STM3020Similar to E. coli putative transcriptional regulator LYSR-type (AAC73606.1); Blastp hit to AAC73606.1 (308 aa), 26% identity in aa 2 - 275; Belongs to the LysR transcriptional regulatory family. (287 aa)
STM3084Putative gntR family regulatory protein; Similar to E. coli regulator for uxu operon (AAC77280.1); Blastp hit to AAC77280.1 (257 aa), 39% identity in aa 8 - 247. (266 aa)
STM3357Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC74613.1); Blastp hit to AAC74613.1 (228 aa), 23% identity in aa 15 - 214. (221 aa)
STM3358Putative gntR family regulatory protein. (209 aa)
yhdVPutative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC76299.1); Blastp hit to AAC76299.1 (73 aa), 98% identity in aa 1 - 73. (73 aa)
crpCatabolite activator protein (CAP); A global transcription regulator. Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding to regulate transcription. It can act as an activator, repressor, coactivator or corepressor. Induces a severe bend in DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP. Plays a major role in carbon catabolite repression (CCR) (By similarity). (210 aa)
gntTGntP family; similar to E. coli high-affinity transport of gluconate / gluconate permease (AAC76440.1); Blastp hit to AAC76440.1 (437 aa), 96% identity in aa 1 - 437. (438 aa)
gntUSimilar to E. coli low-affinity gluconate transport permease protein, interrupted (AAC76461.1); Blastp hit to AAC76461.1 (332 aa), 96% identity in aa 1 - 331. (446 aa)
gntKThermoresistant; similar to E. coli gluconokinase 2, thermoresistant (AAC76462.1); Blastp hit to AAC76462.1 (162 aa), 96% identity in aa 1 - 161. (177 aa)
rbsK-2Putative transcriptional regulator of sugar metabolism; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (404 aa)
STM3602Putative gntR family regulatory protein; Similar to E. coli putative transcriptional regulator (AAC76400.1); Blastp hit to AAC76400.1 (265 aa), 28% identity in aa 27 - 260. (239 aa)
yhjBLuxR/UhpA family; similar to E. coli putative regulator (AAC76545.1); Blastp hit to AAC76545.1 (200 aa), 72% identity in aa 1 - 200. (200 aa)
STM3633Putative bacterial regulatory protein; lacI family; similar to E. coli regulator for rbs operon (AAC76776.1); Blastp hit to AAC76776.1 (330 aa), 27% identity in aa 2 - 304. (335 aa)
xylBXylulokinase; Similar to E. coli xylulokinase (AAC76588.1); Blastp hit to AAC76588.1 (484 aa), 85% identity in aa 1 - 484. (484 aa)
xylASimilar to E. coli D-xylose isomerase (AAC76589.1); Blastp hit to AAC76589.1 (440 aa), 92% identity in aa 1 - 440. (440 aa)
xylRXylose operon regulatory protein; AraC/XylS family; similar to E. coli putative regulator of xyl operon (AAC76593.1); Blastp hit to AAC76593.1 (392 aa), 92% identity in aa 1 - 392. (392 aa)
avtAValine-pyruvate aminotransferase; Similar to E. coli alanine-alpha-ketoisovalerate (or valine-pyruvate) transaminase, transaminase C (AAC76596.1); Blastp hit to AAC76596.1 (417 aa), 92% identity in aa 1 - 415. (416 aa)
STM3678araC family; similar to E. coli putative ARAC-type regulatory protein (AAC76936.1); Blastp hit to AAC76936.1 (283 aa), 25% identity in aa 112 - 274. (271 aa)
STM3679Putative cytoplasmic protein. (651 aa)
yicIPutative alpha-xylosidase; Similar to E. coli orf, hypothetical protein (AAC76680.1); Blastp hit to AAC76680.1 (772 aa), 88% identity in aa 1 - 772; Belongs to the glycosyl hydrolase 31 family. (772 aa)
STM3780Putative fructose-bisphosphate aldolase class-II; Similar to E. coli tagatose-bisphosphate aldolase 2 (AAC76171.1); Blastp hit to AAC76171.1 (286 aa), 36% identity in aa 1 - 277. (286 aa)
STM3781Putative sugar (pentulose and hexulose) kinase; Similar to E. coli L-fuculokinase (AAC75845.1); Blastp hit to AAC75845.1 (482 aa), 24% identity in aa 17 - 444. (494 aa)
STM3785Putative gntR family regulatory protein; Similar to E. coli transcriptional regulator of succinylCoA synthetase operon (AAC73824.1); Blastp hit to AAC73824.1 (240 aa), 31% identity in aa 3 - 216. (247 aa)
yicNPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76686.1); Blastp hit to AAC76686.1 (159 aa), 82% identity in aa 10 - 159. (150 aa)
uhpTMFS family hexose phosphate transport protein; Mediates the exchange of external hexose 6-phosphate and internal inorganic phosphate. (463 aa)
uhpCRegulator of uhpT expression; Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT. UhpC senses external glucose-6-phosphate and interacts with the histidine kinase UhpB, leading to the stimulation of the autokinase activity of UhpB. Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family. (442 aa)
uhpBSensory histidine kinase in two-component regulatory sytem with UhpA; Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT. UhpB functions as a membrane-associated protein kinase that autophosphorylates in response to interaction with UhpC, and subsequently transfers its phosphate group to the response regulator UhpA. Can also dephosphorylate UhpA. (500 aa)
uhpAResponse regulator (repressor) in two-component regulatory system wtih UhpB; Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT. Activates the transcription of the uhpT gene. Acts by binding specifically to the uhpT promoter region. (196 aa)
STM3791Putative cytoplasmic protein. (337 aa)
STM3792Putative L-fucose permease; Similar to E. coli fucose permease (AAC75843.1); Blastp hit to AAC75843.1 (438 aa), 34% identity in aa 17 - 428. (438 aa)
STM3794Putative deoR family regulatory protein; Similar to E. coli transcriptional repressor for deo operon, tsx, nupG (AAC73927.1); Blastp hit to AAC73927.1 (252 aa), 38% identity in aa 1 - 251. (261 aa)
rbsDD-ribose high-affinity transport system; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (139 aa)
rbsAD-ribose high-affinity transport protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (501 aa)
rbsCD-ribose high-affinity transport protein (1st module, ATP-binding subunit); ABC superfamily (membrane); similar to E. coli D-ribose high-affinity transport system (AAC76773.1); Blastp hit to AAC76773.1 (321 aa), 96% identity in aa 1 - 321; Belongs to the binding-protein-dependent transport system permease family. (321 aa)
rbsBD-ribose transport protein; Part of the ABC transporter complex RbsABC involved in ribose import. Binds ribose. (296 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (309 aa)
rbsRTranscriptional repressor for rbs operon (GalR/LacI family); Similar to E. coli regulator for rbs operon (AAC76776.1); Blastp hit to AAC76776.1 (330 aa), 89% identity in aa 1 - 329. (332 aa)
yiePPutative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC76778.1); Blastp hit to AAC76778.1 (181 aa), 82% identity in aa 1 - 181. (234 aa)
cyaAAdenylate cyclase. (SW:CYAA_SALTY). (848 aa)
STMD1.48Putative inner membrane protein. (180 aa)
yiiLPutative cytoplasmic protein; Involved in the anomeric conversion of L-rhamnose. (104 aa)
rhaDRhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Belongs to the aldolase class II family. RhaD subfamily. (275 aa)
rhaAL-rhamnose isomerase. (SW:RHAA_SALTY). (419 aa)
rhaBRhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Belongs to the rhamnulokinase family. (489 aa)
rhaSPositive regulator for rhaBAD operon; Activates expression of the rhaBAD and rhaT operons. (278 aa)
rhaRPositive regulator for rhaRS operon; Activates expression of the rhaSR operon in response to L- rhamnose. (282 aa)
rhaTDMT Superfamily L-rhamnose:H+ symporter protein; Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system); Belongs to the L-rhamnose transporter (TC 2.A.7.6) family. (344 aa)
STM4065Putative permease of the Na+:galactoside symporter family; Hypothetical protein (gi|7688349). (444 aa)
STM4066Putative sugar kinase; Ribokinase family; similar to E. coli putative kinase (AAD13445.1); Blastp hit to AAD13445.1 (300 aa), 28% identity in aa 14 - 297; Belongs to the carbohydrate kinase PfkB family. (319 aa)
STM4067Putative ADP-ribosylglycohydrolase; Similar to E. coli orf, hypothetical protein (AAC75160.1); Blastp hit to AAC75160.1 (334 aa), 30% identity in aa 108 - 325, 32% identity in aa 5 - 188. (346 aa)
STM4068Putative gntR family regulatory protein; Similar to E. coli transcriptional regulator of succinylCoA synthetase operon (AAC73824.1); Blastp hit to AAC73824.1 (240 aa), 28% identity in aa 5 - 220. (240 aa)
STM4071Putative mannose-6-phosphate isomerase. (88 aa)
ydeVPutative sugar kinase; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position; Belongs to the FGGY kinase family. (530 aa)
ydeWPutative transcriptional repressor; In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFGE operon and its own transcription. In the presence of AI-2, LsrR is inactivated by binding phospho-AI-2, leading to the transcription of the lsr genes. (319 aa)
egoPutative ABC-type sugar aldose transport system; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system (Probable). (511 aa)
ydeYPutative sugar transport protein; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane (Probable). Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily. (347 aa)
ydeZPutative sugar transport protein; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane (Probable). Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily. (333 aa)
yneAPutative sugar transport protein; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (Probable); Belongs to the bacterial solute-binding protein 2 family. (340 aa)
yneBPutative fructose-1,6-bisphosphate aldolase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5- phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA. (291 aa)
yneCPutative inner membrane protein; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD). (109 aa)
cytRGalR/LacI family transcriptional repressor; Similar to E. coli regulator for deo operon, udp, cdd, tsx, nupC, and nupG (AAC76916.1); Blastp hit to AAC76916.1 (341 aa), 86% identity in aa 1 - 341. (341 aa)
yijOSimilar to E. coli putative ARAC-type regulatory protein (AAC76936.1); Blastp hit to AAC76936.1 (283 aa), 89% identity in aa 1 - 282. (283 aa)
melRAraC/XylS family; similar to E. coli regulator of melibiose operon (AAC77079.1); Blastp hit to AAC77079.1 (302 aa), 88% identity in aa 4 - 302. (310 aa)
yjeJPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77105.1); Blastp hit to AAC77105.1 (289 aa), 58% identity in aa 1 - 283. (285 aa)
treRTranscriptional repressor of treABC; Repressor of the treBC operon. It is able to bind trehalose- 6-phosphate. (315 aa)
idnRL-idonate regulator; GalR/LacI family; similar to E. coli L-idonate transcriptional regulator (AAC77221.1); Blastp hit to AAC77221.1 (332 aa), 89% identity in aa 1 - 332. (332 aa)
idnTGntP family L-idonate transport protein; Similar to E. coli L-idonate transporter (AAC77222.1); Blastp hit to AAC77222.1 (439 aa), 94% identity in aa 1 - 439. (439 aa)
idnO5-keto-D-gluconate-5-reductase; Similar to E. coli 5-keto-D-gluconate 5-reductase (AAC77223.1); Blastp hit to AAC77223.1 (254 aa), 92% identity in aa 1 - 254; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (254 aa)
idnDSimilar to E. coli L-idonate dehydrogenase (AAC77224.1); Blastp hit to AAC77224.1 (343 aa), 82% identity in aa 1 - 343. (343 aa)
idnKSimilar to E. coli gluconate kinase, thermosensitive glucokinase (AAC77225.1); Blastp hit to AAC77225.1 (187 aa), 86% identity in aa 1 - 171. (176 aa)
STM4502Putative cytoplasmic protein. (202 aa)
uxuRSimilar to E. coli regulator for uxu operon (AAC77280.1); Blastp hit to AAC77280.1 (257 aa), 89% identity in aa 1 - 257. (257 aa)
robTranscriptional regulator; AraC/XylS family; similar to E. coli right origin-binding protein (AAC77349.1); Blastp hit to AAC77349.1 (289 aa), 92% identity in aa 1 - 289. (289 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (14%) [HD]