STRINGSTRING
STM0954 STM0954 aat aat rimJ rimJ yncA yncA ydcP ydcP ydcN ydcN STM1606 STM1606 rimL rimL STM1664 STM1664 STM1665 STM1665 STM1857 STM1857 elaA elaA STM2446 STM2446 STM2447 STM2447 yfeZ yfeZ ypeA ypeA ypfK ypfK ypfL ypfL ypfI ypfI yfiP yfiP yfiQ yfiQ yfiM yfiM yhbS yhbS yhhY yhhY yhhK yhhK yiaC yiaC STM4010 STM4010 STM4011 STM4011 STM4012 STM4012 STM4013 STM4013 STM4014 STM4014 STM4015 STM4015 yshA yshA yihO yihO yihP yihP yihQ yihQ yihR yihR yihS yihS yihT yihT yihU yihU yihV yihV yihW yihW yihX yihX rbn rbn yihZ yihZ yiiD yiiD STM4041 STM4041 STM4042 STM4042 STM4042A STM4042A yjaB yjaB phnO phnO yjgM yjgM rimI rimI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STM0954Putative inner membrane protein. (127 aa)
aatLeucyl, phenylalanyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. (234 aa)
rimJSimilar to E. coli acetylation of N-terminal alanine of 30S ribosomal subunit protein S5 (AAC74150.1); Blastp hit to AAC74150.1 (194 aa), 95% identity in aa 1 - 194. (194 aa)
yncAPutative acyltransferase; Plays a role in the resistance against the toxic effects of L-methionine sulfoximine (MSX), a rare amino acid which inhibits glutamine synthetase (GlnA). Catalyzes the acetylation of MSX. It can also use L-methionine sulfone (MSO). Also catalyzes the acylation of free L-amino acids using an acyl-CoA as acyl donor (By similarity). (171 aa)
ydcPSimilar to E. coli putative collagenase (AAC74517.1); Blastp hit to AAC74517.1 (667 aa), 92% identity in aa 20 - 667. (654 aa)
ydcNPutative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74516.1); Blastp hit to AAC74516.1 (178 aa), 72% identity in aa 1 - 177; putative repressor. (178 aa)
STM1606Similar to E. coli putative membrane transport protein (AAC74515.1); Blastp hit to AAC74515.1 (478 aa), 76% identity in aa 88 - 469. (392 aa)
rimLAcetyl transferase; Modifies N-terminal serine of 50S ribosomal subunit protein L7/L12; similar to E. coli acetylation of N-terminal serine of 30S ribosomal subunit protein L7; acetyl transferase (AAC74509.1); Blastp hit to AAC74509.1 (179 aa), 67% identity in aa 1 - 178. (179 aa)
STM1664Putative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC74516.1); Blastp hit to AAC74516.1 (178 aa), 28% identity in aa 8 - 169. (200 aa)
STM1665Putative cytoplasmic protein. (228 aa)
STM1857Putative acetyltransferase. (139 aa)
elaAPutative acyltransferase; Similar to E. coli orf, hypothetical protein (AAC75327.1); Blastp hit to AAC75327.1 (153 aa), 80% identity in aa 1 - 153. (153 aa)
STM2446Putative iron-dependent peroxidase; Similar to E. coli orf, hypothetical protein (AAC75484.1); Blastp hit to AAC75484.1 (308 aa), 94% identity in aa 10 - 308. (299 aa)
STM2447Putative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC75485.1); Blastp hit to AAC75485.1 (191 aa), 80% identity in aa 1 - 191. (191 aa)
yfeZPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75486.1); Blastp hit to AAC75486.1 (151 aa), 73% identity in aa 3 - 151. (149 aa)
ypeAPutative acetyltransferase; Similar to E. coli orf, hypothetical protein (AAC75487.1); Blastp hit to AAC75487.1 (178 aa), 85% identity in aa 1 - 178; Belongs to the acetyltransferase family. YpeA subfamily. (178 aa)
ypfKPutative inner membrane protein; Hypothetical protein in eutR-hemF intergenic region (ORF33). (SW:YPFK_SALTY). (109 aa)
ypfLPutative cytoplasmic protein; Hypothetical 30.0 Kda protein in eutR-hemF intergenic region (ORF79). (SW:YPFL_SALTY). (425 aa)
ypfIPutative acetyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (672 aa)
yfiPPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75636.1); Blastp hit to AAC75636.1 (240 aa), 88% identity in aa 9 - 234. (226 aa)
yfiQPutative acetyl-CoA synthetase; Acetylates and inactivates the acetyl-CoA synthase (Acs). Can also acetylate other central metabolic enzymes in response to environmental changes; In the central section; belongs to the acetate CoA ligase beta subunit family. (886 aa)
yfiMPutative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC75639.1); Blastp hit to AAC75639.1 (90 aa), 80% identity in aa 1 - 90. (107 aa)
yhbSPutative ABC superfamily transport protein; Membrane; similar to E. coli orf, hypothetical protein (AAC76190.1); Blastp hit to AAC76190.1 (167 aa), 96% identity in aa 1 - 167. (167 aa)
yhhYPutative transferase; Similar to E. coli orf, hypothetical protein (AAC76466.1); Blastp hit to AAC76466.1 (162 aa), 82% identity in aa 1 - 162. (162 aa)
yhhKPutative acetyltransferase; Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion (By similarity). Binding of CoA or a derivative to PanM leads to interaction with PanD, which promotes the processing and activation of pro-PanD, and subsequent substrate- mediated inhibition of the active form of PanD (By similarity). Lacks acetyltransferase activity. (127 aa)
yiaCPutative acetyltransferase; Similar to E. coli orf, hypothetical protein (AAC76574.1); Blastp hit to AAC76574.1 (146 aa), 60% identity in aa 1 - 145. (146 aa)
STM4010Similar to E. coli putative phosphatase (AAC73853.1); Blastp hit to AAC73853.1 (272 aa), 44% identity in aa 147 - 267, 30% identity in aa 1 - 169. (244 aa)
STM4011Putative inner membrane protein. (292 aa)
STM4012Putative coproporphyrinogen III oxidase and related FeS oxidoreductase; Similar to E. coli O2-independent coproporphyrinogen III oxidase (AAC76864.1); Blastp hit to AAC76864.1 (459 aa), 28% identity in aa 14 - 248, 25% identity in aa 319 - 379. (413 aa)
STM4013Putative membrane-associated metal-dependent hydrolase. (291 aa)
STM4014Putative periplasmic protein. (341 aa)
STM4015Putative cytoplasmic protein. (282 aa)
yshAPutative outer membrane protein; Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is unknown (By similarity); Belongs to the oligogalacturonate-specific porin KdgM (TC 1.B.35) family. OmpL subfamily. (230 aa)
yihOPutative GPH family transport protein; Could be involved in sulfoquinovose import; Belongs to the sodium:galactoside symporter (TC 2.A.2) family. (473 aa)
yihPPutative GPH family transport protein; Could be involved in the export of 2,3-dihydroxypropane-1- sulfonate (DHPS); Belongs to the sodium:galactoside symporter (TC 2.A.2) family. (460 aa)
yihQSimilar to E. coli putative glycosidase (AAC76875.1); Blastp hit to AAC76875.1 (678 aa), 88% identity in aa 10 - 678; Belongs to the glycosyl hydrolase 31 family. (678 aa)
yihRSimilar to E. coli putative aldose-1-epimerase (AAC76876.1); Blastp hit to AAC76876.1 (308 aa), 54% identity in aa 9 - 303. (285 aa)
yihSPutative isomerase; Catalyzes the isomerization of sulfoquinovose (SQ) to 6- deoxy-6-sulfo-D-fructose (SF) (By similarity). In vitro, can also catalyze the interconversion of mannose, fructose and glucose, but has extremely low activity with glucose. Belongs to the N-acylglucosamine 2-epimerase family. (413 aa)
yihTPutative aldolase; Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA). Belongs to the aldolase LacD family. (292 aa)
yihUPutative oxidoreductase; Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1- sulfonate (DHPS); Belongs to the HIBADH-related family. 3-sulfolactaldehyde reductase subfamily. (298 aa)
yihVPutative sugar kinase; Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6-deoxy-6- sulfo-D-fructose 1-phosphate (SFP); Belongs to the carbohydrate kinase PfkB family. (298 aa)
yihWPutative glycerol-3-phosphate regulon repressor; DeoR family; similar to E. coli putative DEOR-type transcriptional regulator (AAD13446.1); Blastp hit to AAD13446.1 (269 aa), 89% identity in aa 9 - 263. (267 aa)
yihXSimilar to E. coli putative phosphatase (AAD13447.1); Blastp hit to AAD13447.1 (206 aa), 89% identity in aa 8 - 206. (199 aa)
rbnSimilar to E. coli tRNA processing exoribonuclease BN (AAD13448.1); Blastp hit to AAD13448.1 (290 aa), 93% identity in aa 1 - 290. (290 aa)
yihZD-Tyr-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (145 aa)
yiiDSimilar to E. coli putative acetyltransferase (AAD13450.1); Blastp hit to AAD13450.1 (329 aa), 93% identity in aa 1 - 329. (329 aa)
STM4041Putative inner membrane protein. (107 aa)
STM4042Putative branched-chain amino acid permease; Similar to E. coli orf, hypothetical protein (AAC74516.1); Blastp hit to AAC74516.1 (178 aa), 25% identity in aa 8 - 160. (219 aa)
STM4042AHypothetical protein. (188 aa)
yjaBPutative acetyltransferase; N-epsilon-lysine acetyltransferase that catalyzes acetylation of a large number of proteins; Belongs to the acetyltransferase family. (145 aa)
phnOPutative regulator in phn operon; Aminoalkylphosphonate N-acetyltransferase which is able to acetylate a range of aminoalkylphosphonic acids, including (S)-1- aminoethylphosphonate ((S)-1AEP) and 2-aminoethylphosphonate, using acetyl-CoA as acetyl donor. Its physiological role in S.typhimurium is unclear. However, by acetylating (S)-1AEP, PhnO would protect against the deleterious effects of (S)-1AEP, a structural analog of D-alanine that has antibacterial properties. (154 aa)
yjgMPutative acetyltransferase; Hypothetical 18.3 Kda protein in miaE 3'region (ORF 18.3). (SW:YJGM_SALTY); Belongs to the acetyltransferase family. (167 aa)
rimIModification of 30S ribosomal subunit protein S18; Acetylates the N-terminal alanine of ribosomal protein S18. (148 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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