STRINGSTRING
STM0014 STM0014 STM0016 STM0016 STM0017 STM0017 STM0018 STM0018 STM0019 STM0019 STM0020 STM0020 STM0233 STM0233 hpaC hpaC hpaB hpaB hpaR hpaR hpaG hpaG hpaE hpaE hpaD hpaD hpaF hpaF hpaH hpaH hpaI hpaI hpaX hpaX hpaA hpaA STM1109 STM1109 yneI yneI STM1871 STM1871 STM2273 STM2273 STM2274 STM2274 STM2288 STM2288 yfaV yfaV yfaW yfaW yfaX yfaX yfaZ yfaZ tctE tctE tctD tctD STM2786 STM2786 STM2787 STM2787 STM2788 STM2788 glaH glaH ygaF ygaF gabD gabD gabT gabT gabP gabP ygaE ygaE STM3125 STM3125 STM3126 STM3126 STM3127 STM3127 STM3128 STM3128 STM3129 STM3129 STM3697 STM3697 STM3698 STM3698 STM4302 STM4302 STM4309 STM4309 tnpA_6 tnpA_6 STM4314 STM4314 STM4315 STM4315 STM4503 STM4503 STM4518 STM4518 STM4519 STM4519
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STM0014Similar to E. coli putative transcriptional regulator LYSR-type (AAC73704.1); Blastp hit to AAC73704.1 (300 aa), 25% identity in aa 8 - 296; Belongs to the LysR transcriptional regulatory family. (315 aa)
STM0016Hypothetical protein. (177 aa)
STM0017Similar to E. coli putative sensory transducer (AAC75886.1); Blastp hit to AAC75886.1 (269 aa), 30% identity in aa 3 - 109. (147 aa)
STM0018Putative exochitinase. (699 aa)
STM0019Putative hydroxymethyltransferase. (998 aa)
STM0020Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73478.1); Blastp hit to AAC73478.1 (222 aa), 32% identity in aa 21 - 222. (234 aa)
STM0233Putative endochitinase. (587 aa)
hpaC4-hydroxyphenylacetate catabolism protein; Catalyzes the reduction of free flavins (FMN, FAD and riboflavin) by NADH. Subsequently, the reduced flavins diffuse to the large HpaB component or to other electron acceptors such as cytochrome c and Fe(3+) ion (By similarity); Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily. (170 aa)
hpaB4-hydroxyphenylacetate catabolism protein. (520 aa)
hpaR4-hydroxyphenylacetate catabolism protein. (146 aa)
hpaG4-hydroxyphenylacetate catabolism protein; Similar to E. coli putative isomerase (AAC74264.1); Blastp hit to AAC74264.1 (219 aa), 38% identity in aa 22 - 219, 29% identity in aa 35 - 211. (429 aa)
hpaE4-hydroxyphenylacetate catabolism protein; Similar to E. coli aldehyde dehydrogenase, prefers NADP over NAD (AAC74382.1); Blastp hit to AAC74382.1 (495 aa), 39% identity in aa 23 - 493. (488 aa)
hpaD4-hydroxyphenylacetate catabolism protein. (283 aa)
hpaF4-hydroxyphenylacetate catabolism protein. (126 aa)
hpaH4-hydroxyphenylacetate catabolism protein; Similar to E. coli 2-keto-4-pentenoate hydratase (AAC73453.1); Blastp hit to AAC73453.1 (271 aa), 34% identity in aa 6 - 261. (267 aa)
hpaI4-hydroxyphenylacetate catabolism protein; Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2- ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde. (263 aa)
hpaX4-hydroxyphenylacetate catabolism protein; Similar to E. coli putative transport protein (AAC75306.1); Blastp hit to AAC75306.1 (442 aa), 31% identity in aa 22 - 428. (458 aa)
hpaA4-hydroxyphenylacetate catabolism protein; Similar to E. coli putative ARAC-type regulatory protein (AAC74766.1); Blastp hit to AAC74766.1 (303 aa), 25% identity in aa 181 - 281. (298 aa)
STM1109Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75328.1); Blastp hit to AAC75328.1 (311 aa), 27% identity in aa 7 - 147, 27% identity in aa 155 - 277. (312 aa)
yneISimilar to E. coli putative aldehyde dehydrogenase (AAC74598.1); Blastp hit to AAC74598.1 (470 aa), 81% identity in aa 9 - 470. (462 aa)
STM1871Similar to E. coli prophage e14 integrase (AAC74224.1); Blastp hit to AAC74224.1 (375 aa), 39% identity in aa 78 - 366; Belongs to the 'phage' integrase family. (298 aa)
STM2273Putative dehydratase protein; Similar to E. coli starvation sensing protein (AAC74653.1); Blastp hit to AAC74653.1 (404 aa), 30% identity in aa 198 - 384, 36% identity in aa 1 - 120; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (400 aa)
STM2274Similar to E. coli putative transport protein (AAC75306.1); Blastp hit to AAC75306.1 (442 aa), 30% identity in aa 18 - 428. (441 aa)
STM2288Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75309.1); Blastp hit to AAC75309.1 (400 aa), 83% identity in aa 342 - 397. (58 aa)
yfaVSimilar to E. coli putative transport protein (AAC75306.1); Blastp hit to AAC75306.1 (442 aa), 91% identity in aa 14 - 442. (429 aa)
yfaWPutative galactonate dehydratase; Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy- L-rhamnonate (KDR). Can also dehydrate L-lyxonate and L-mannonate, although less efficiently, but not 2-keto-4-hydroxyheptane-1,7-dioate. Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily. (405 aa)
yfaXSimilar to E. coli putative regulator (AAC75308.1); Blastp hit to AAC75308.1 (260 aa), 87% identity in aa 1 - 260. (260 aa)
yfaZPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75310.1); Blastp hit to AAC75310.1 (187 aa), 86% identity in aa 8 - 187. (215 aa)
tctETricarboxylic transport regulatory protein; Similar to E. coli putative 2-component sensor protein (AAC76062.1); Blastp hit to AAC76062.1 (449 aa), 30% identity in aa 160 - 447, 29% identity in aa 1 - 56. (471 aa)
tctDTricarboxylic transport regulatory protein; Transcriptional activator of the tctI tricarboxylate transport system operon. (224 aa)
STM2786Tricarboxylic transport protein. (325 aa)
STM2787Tricarboxylic transport protein. (144 aa)
STM2788Tricarboxylic transport protein. (504 aa)
glaHPutative cytoplasmic protein; Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (328 aa)
ygaFPutative sarcosine oxidase-like protein; Catalyzes the dehydrogenation of L-2-hydroxyglutarate (L2HG) to alpha-ketoglutarate and couples to the respiratory chain by feeding electrons from the reaction into the membrane quinone pool. Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. Reaction=(S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol; Xref=Rhea:RHEA:58664, ChEBI:CHEBI:16782, ChEBI:CHEBI:16810, ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:58665; Belongs to the L2 [...] (422 aa)
gabDSimilar to E. coli succinate-semialdehyde dehydrogenase, NADP-dependent activity (AAC75708.1); Blastp hit to AAC75708.1 (482 aa), 90% identity in aa 1 - 482. (482 aa)
gabTSimilar to E. coli 4-aminobutyrate aminotransferase activity (AAC75709.1); Blastp hit to AAC75709.1 (426 aa), 88% identity in aa 1 - 426; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
gabPAPC family; similar to E. coli transport permease protein of gamma-aminobutyrate (AAC75710.1); Blastp hit to AAC75710.1 (466 aa), 92% identity in aa 1 - 466. (466 aa)
ygaEPutative GntR family transcriptional repressor; Similar to E. coli putative transcriptional regulator (AAC75711.1); Blastp hit to AAC75711.1 (226 aa), 87% identity in aa 10 - 225. (225 aa)
STM3125Putative cytoplasmic protein. (185 aa)
STM3126Putative amino acid transporter; Similar to E. coli proline permease transport protein (AAC73505.1); Blastp hit to AAC73505.1 (457 aa), 25% identity in aa 4 - 415. (499 aa)
STM3127Putative cytoplasmic protein. (124 aa)
STM3128Similar to E. coli probable oxidoreductase (AAC74383.1); Blastp hit to AAC74383.1 (426 aa), 35% identity in aa 7 - 414. (433 aa)
STM3129Similar to E. coli phenylacetaldehyde dehydrogenase (AAC74467.1); Blastp hit to AAC74467.1 (500 aa), 44% identity in aa 7 - 500. (494 aa)
STM3697Putative mandelate racemase; Catalyzes the efficient dehydration of both L-talarate and galactarate to 5-keto-4-deoxy-D-glucarate. Also catalyzes the epimerization of L-talarate to galactarate; epimerization occurs in competition with dehydration. Is required for the utilization of L- talarate as a carbon source. Also functions in galactarate utilization. Is not active on other acid sugars; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (398 aa)
STM3698Similar to E. coli putative transport protein (AAC75831.1); Blastp hit to AAC75831.1 (450 aa), 49% identity in aa 9 - 444. (436 aa)
STM4302Putative cytoplasmic protein. (88 aa)
STM4309Putative periplasmic or exported protein. (466 aa)
tnpA_6Transposase for insertion sequence element IS200 (SW:T200_SALTY). (152 aa)
STM4314Putative luxR family bacterial regulatory proteins. (95 aa)
STM4315Putative AraC-type DNA-binding domain-containing protein; HilD (gi|4455108). (291 aa)
STM4503Putative inner membrane protein; Unknown (gi|5616505). (245 aa)
STM4518Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75304.1); Blastp hit to AAC75304.1 (299 aa), 45% identity in aa 187 - 277, 73% identity in aa 1 - 42, 36% identity in aa 216 - 295. (171 aa)
STM4519Similar to E. coli putative aldehyde dehydrogenase (AAC74598.1); Blastp hit to AAC74598.1 (470 aa), 42% identity in aa 19 - 465. (456 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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