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mrcB mrcB STM3277 STM3277 dacB dacB mrcA mrcA ybiS ybiS dacC dacC ycbB ycbB ycfS ycfS ynhG ynhG ftsI-2 ftsI-2 mrdA-2 mrdA-2 erfK erfK dacD dacD pbpG pbpG yfeW yfeW dacA dacA mrdA mrdA ftsI ftsI yafK yafK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mrcBTranspeptidase of penicillin-binding protein 1b; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (840 aa)
STM3277Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC73328.1); Blastp hit to AAC73328.1 (246 aa), 51% identity in aa 30 - 224. (239 aa)
dacBSimilar to E. coli D-alanyl-D-alanine carboxypeptidase, fraction B; penicillin-binding protein 4 (AAC76214.1); Blastp hit to AAC76214.1 (477 aa), 93% identity in aa 1 - 477. (477 aa)
mrcASimilar to E. coli peptidoglycan synthetase; penicillin-binding protein 1A (AAC76421.1); Blastp hit to AAC76421.1 (858 aa), 92% identity in aa 1 - 858. (858 aa)
ybiSPutative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73906.1); Blastp hit to AAC73906.1 (306 aa), 92% identity in aa 1 - 306. (306 aa)
dacCSimilar to E. coli D-alanyl-D-alanine carboxypeptidase; penicillin-binding protein 6 (AAC73926.1); Blastp hit to AAC73926.1 (400 aa), 92% identity in aa 1 - 400; Belongs to the peptidase S11 family. (400 aa)
ycbBPutative periplasmic protein; Similar to E. coli putative amidase (AAC74011.1); Blastp hit to AAC74011.1 (615 aa), 84% identity in aa 1 - 615. (613 aa)
ycfSPutative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74197.1); Blastp hit to AAC74197.1 (320 aa), 84% identity in aa 1 - 320. (321 aa)
ynhGPutative LysM domain protein; Similar to E. coli orf, hypothetical protein (AAC74748.1); Blastp hit to AAC74748.1 (334 aa), 85% identity in aa 1 - 334. (333 aa)
ftsI-2Putative penicillin-binding protein-3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (581 aa)
mrdA-2Putative penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (623 aa)
erfKPutative periplasmic protein; Protein ERKF/SRFK precursor. (SW:ERFK_SALTY); Belongs to the YkuD family. (309 aa)
dacDDD-carboxypeptidase; Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Belongs to the peptidase S11 family. (390 aa)
pbpGD-alanyl-D-alanine endopeptidase; Penicillin-binding protein 7 and penicillin-binding protein 8; similar to E. coli penicillin-binding protein 7 (AAC75195.1); Blastp hit to AAC75195.1 (313 aa), 92% identity in aa 4 - 313; Belongs to the peptidase S11 family. (315 aa)
yfeWSimilar to E. coli putative beta-lactamase (AAC75483.1); Blastp hit to AAC75483.1 (463 aa), 72% identity in aa 30 - 461; Belongs to the peptidase S12 family. YfeW subfamily. (432 aa)
dacASimilar to E. coli D-alanyl-D-alanine carboxypeptidase, fraction A; penicillin-binding protein 5 (AAC73733.1); Blastp hit to AAC73733.1 (403 aa), 95% identity in aa 1 - 403; Belongs to the peptidase S11 family. (403 aa)
mrdACell elongation specific transpeptidase of penicillin-binding protein 2 (peptidoglycan synthetase); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (633 aa)
ftsIDivision specific transpeptidase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (588 aa)
yafKPutative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73328.1); Blastp hit to AAC73328.1 (246 aa), 90% identity in aa 1 - 246. (246 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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