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| | ybhC | Similar to E. coli putative pectinesterase (AAC73859.1); Blastp hit to AAC73859.1 (427 aa), 86% identity in aa 1 - 427. (427 aa) |
| | ybhE | Putative 3-carboxymuconate cyclase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. (331 aa) |
| | ybhA | Putative hydrolase of the HAD superfamily; Similar to E. coli putative phosphatase (AAC73853.1); Blastp hit to AAC73853.1 (272 aa), 84% identity in aa 1 - 272. (272 aa) |
| | ybgC | Putative esterase; Similar to E. coli orf, hypothetical protein (AAC73830.1); Blastp hit to AAC73830.1 (134 aa), 92% identity in aa 1 - 134. (134 aa) |
| | ybfF | Putative enzyme; Similar to E. coli orf, hypothetical protein (AAC73780.1); Blastp hit to AAC73780.1 (254 aa), 89% identity in aa 1 - 254. (256 aa) |
| | nagD | Similar to E. coli N-acetylglucosamine metabolism (AAC73769.1); Blastp hit to AAC73769.1 (250 aa), 96% identity in aa 1 - 250. (250 aa) |
| | ybeY | Putative metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (157 aa) |
| | leuS | Similar to E. coli leucine tRNA synthetase (AAC73743.1); Blastp hit to AAC73743.1 (860 aa), 95% identity in aa 1 - 860; Belongs to the class-I aminoacyl-tRNA synthetase family. (860 aa) |
| | cobC | Alpha ribazole-5'-P phosphatase in cobalamin synthesis; Catalyzes the conversion of adenosylcobalamin 5'-phosphate to adenosylcobalamin (vitamin B12); involved in the assembly of the nucleotide loop of cobalamin. Also catalyzes the hydrolysis of the phospho group from alpha-ribazole 5'-phosphate to form alpha-ribazole. (202 aa) |
| | rna | Similar to E. coli RNase I, cleaves phosphodiester bond between any two nucleotides (AAC73712.1); Blastp hit to AAC73712.1 (268 aa), 73% identity in aa 1 - 268; Belongs to the RNase T2 family. (268 aa) |
| | ybdB | Putative protein PaaI, possibly involved in aromatic compounds catabolism; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. (137 aa) |
| | fes | Similar to E. coli enterochelin esterase (AAC73686.1); Blastp hit to AAC73686.1 (374 aa), 74% identity in aa 2 - 369. (404 aa) |
| | apeE | Outer membrane N-acetyl phenylalanine beta-naphthyl ester-cleaving esterase; Outer membrane esterase (gi|2896133). (656 aa) |
| | STM0561 | Sensor protein; Similar to E. coli putative 2-component sensor protein (AAC73671.1); Blastp hit to AAC73671.1 (480 aa), 74% identity in aa 375 - 479. (109 aa) |
| | tesA | Similar to E. coli acyl-CoA thioesterase I; also functions as protease I (AAC73596.1); Blastp hit to AAC73596.1 (208 aa), 89% identity in aa 2 - 205. (204 aa) |
| | ybaK | Putative cytoplasmic protein; Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity. (159 aa) |
| | ushA | UDP-sugar hydrolase 5'-nucleotidase; Silent protein USHA(0) precursor. (SW:USHA_SALTY); Belongs to the 5'-nucleotidase family. (550 aa) |
| | aes | Acetyl esterase; Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity. (323 aa) |
| | pnp | Polynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. Is a global regulator of virulence and persistency. (711 aa) |
| | cca | tRNA nucleotidyl transferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (413 aa) |
| | glnE | Adenylyl transferase for glutamine synthetase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal trans [...] (947 aa) |
| | icc | Cyclic 3',5'-adenosine monophosphate phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (275 aa) |
| | STM3122 | Similar to E. coli putative sulfatase (AAC74571.1); Blastp hit to AAC74571.1 (571 aa), 27% identity in aa 120 - 327, 43% identity in aa 322 - 358, 37% identity in aa 44 - 86, 31% identity in aa 435 - 471. (579 aa) |
| | STM3118 | Putative acetyl-CoA hydrolase; Similar to E. coli putative coenzyme A transferase (AAC75957.1); Blastp hit to AAC75957.1 (492 aa), 27% identity in aa 187 - 458, 24% identity in aa 8 - 169. (441 aa) |
| | yqgF | Putative endonuclease involved in recombination; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (138 aa) |
| | endA | Similar to E. coli DNA-specific endonuclease I (AAC75982.1); Blastp hit to AAC75982.1 (235 aa), 87% identity in aa 1 - 235. (235 aa) |
| | recJ | ssDNA exonuclease; Single-stranded-DNA-specific exonuclease. Required for many types of recombinational events, although the stringency of the requirement for RecJ appears to vary with the type of recombinational event monitored and the other recombination gene products which are available. (577 aa) |
| | vapC | Putative nucleic acid-binding protein; Toxic component of a type II toxin-antitoxin (TA) system. A site-specific tRNA-(fMet) endonuclease, it cleaves both charged and uncharged tRNA-(fMet) between positions 38 and 39 at the anticodon stem-loop boundary. Does not cleave tRNA(Met), tRNA(Arg2), tRNA(His), tRNA(Leu), tRNA(Phe) tRNA(Thr1), tRNA(Tyr) or tRNA(Val). Overexpression in E.coli inhibits translation, leads to loss of cell growth and degradation of tRNA(fMet), these effects are neutralized by expression of cognate antitoxin VapB. Expression also activates translation initiation at c [...] (132 aa) |
| | mutH | Methyl-directed mismatch repair protein; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family. (231 aa) |
| | recC | Exonuclease V, subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzy [...] (1123 aa) |
| | recB | Exonuclease V, beta chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoe [...] (1181 aa) |
| | recD | Exonuclease V, alpha chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holo [...] (611 aa) |
| | exo | Exonuclease IX, 5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. (271 aa) |
| | relA | (p)ppGpp synthetase I; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (744 aa) |
| | cas1 | Putative cytoplasmic protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (306 aa) |
| | surE | Survival protein, protein damage control; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. (253 aa) |
| | ygbM | Putative endonuclease; Similar to E. coli orf, hypothetical protein (AAC75781.1); Blastp hit to AAC75781.1 (258 aa), 79% identity in aa 1 - 258; Belongs to the hyi family. (258 aa) |
| | pphB | Serine/threonine specific protein phosphatase 2; Can hydrolyze phosphorylated Ser-, Thr- or Tyr-substrates in vitro. The natural substrate is unknown. (218 aa) |
| | sptP | Protein tyrosine phosphate; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear. In the N-terminal section; belongs to the YopE family. (543 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. (876 aa) |
| | yqaB | Similar to E. coli putative phosphatase (AAC75737.1); Blastp hit to AAC75737.1 (188 aa), 87% identity in aa 1 - 188. (188 aa) |
| | iroE | Putative hydrolase of the alpha/beta superfamily. (311 aa) |
| | iroD | Enterochelin esterase-like protein (Fes); Similar to E. coli enterochelin esterase (AAC73686.1); Blastp hit to AAC73686.1 (374 aa), 31% identity in aa 3 - 362. (414 aa) |
| | STM2729 | Fels-2 prophage protein; Possible endonuclease which induces a single-strand cut and initiates DNA replication. (809 aa) |
| | STM2719 | Fels-2 prophage protein; Similar to gpR in phage 186. (217 aa) |
| | rpsP | 30S ribosomal subunit protein S16; In addition to being a ribosomal protein, S16 also has a cation-dependent endonuclease activity. (82 aa) |
| | STM2668 | Putative cytoplasmic protein. (302 aa) |
| | STM2608 | Gifsy-1 prophage protein; Similar to terminase large chain gp2 of N15; similar to E. coli orf, hypothetical protein (AAC73662.1); Blastp hit to AAC73662.1 (247 aa), 53% identity in aa 7 - 132. (643 aa) |
| | rnc | RNase III, ds RNA; Digests double-stranded RNA. Involved in the processing of ribosomal RNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Removes small helical intervening sequences (IVSs) from all 7 of the 23S rRNA transcripts. Probably also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Probably processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (226 aa) |
| | suhB | Inositol monophosphatase; Similar to E. coli enhances synthesis of sigma32 in mutant; extragenic suppressor, may modulate RNAse III lethal action (AAC75586.1); Blastp hit to AAC75586.1 (267 aa), 97% identity in aa 1 - 267; Belongs to the inositol monophosphatase superfamily. (267 aa) |
| | xseA | Exonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (449 aa) |
| | sixA | Phosphohistidine phosphatase; Similar to E. coli orf, hypothetical protein (AAC75400.1); Blastp hit to AAC75400.1 (161 aa), 89% identity in aa 1 - 161. (161 aa) |
| | yfbT | Similar to E. coli putative phosphatase (AAC75353.1); Blastp hit to AAC75353.1 (222 aa), 86% identity in aa 1 - 221. (225 aa) |
| | yfbR | Putative hydrolase of HD superfamily; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates. (199 aa) |
| | elaC | Putative metal-dependent hydrolase; Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities. (305 aa) |
| | ais | Aluminum inducible protein; Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core. Required for iron(3+) resistance. Belongs to the phosphoglycerate mutase family. Ais subfamily. (201 aa) |
| | glpQ | Similar to E. coli glycerophosphodiester phosphodiesterase, periplasmic (AAC75299.1); Blastp hit to AAC75299.1 (358 aa), 89% identity in aa 1 - 357. (356 aa) |
| | yejM | Putative hydrolase of alkaline phosphatase superfamily; Hypothetical protein in rplY-proL intergenic region. (SW:YEJM_SALTY). (586 aa) |
| | rtn | Putative membrane protein involved in resistance to lambda and N4 phages; Similar to E. coli orf, hypothetical protein (AAC75237.1); Blastp hit to AAC75237.1 (518 aa), 70% identity in aa 1 - 518. (518 aa) |
| | nfo | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. (285 aa) |
| | STM2197 | Similar to E. coli 3-phosphoserine phosphatase (AAC77341.1); Blastp hit to AAC77341.1 (322 aa), 39% identity in aa 111 - 305. (295 aa) |
| | yeiG | Putative esterase; Serine hydrolase involved in the detoxification of formaldehyde. (285 aa) |
| | wzb | Putative protein-tyrosine-phosphatase; Dephosphorylates Wzc. Required for the extracellular polysaccharide colanic acid synthesis. Probably involved in the export of colanic acid from the cell to medium. Involved in protection of cells against contact-dependent growth inhibition (CDI). (149 aa) |
| | hisB | Imidazole glycerol-phosphate dehydratase; Bifunctional; histidine biosynthesis bifunctional protein HISB [includes:histidinol-phosphatase ]. (SW:HIS7_SALTY); In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (355 aa) |
| | sbcB | 3' --> 5' specific; deoxyribophosphodiesterase; similar to E. coli exonuclease I, 3' --> 5' specific; deoxyribophosphodiesterase (AAC75072.1); Blastp hit to AAC75072.1 (475 aa), 93% identity in aa 8 - 475. (476 aa) |
| | vsr | DNA mismatch endonuclease; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination. (156 aa) |
| | yedP | Putative hydrolase of the HAD superfamily; Similar to E. coli orf, hypothetical protein (AAC75021.1); Blastp hit to AAC75021.1 (271 aa), 75% identity in aa 1 - 269. (271 aa) |
| | uvrC | UvrC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (610 aa) |
| | otsB | Trehalose-6-phosphate phophatase, biosynthetic; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. (267 aa) |
| | cheB | Methyl esterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid (By similarity). Belongs to the CheB family. (349 aa) |
| | cheZ | Chemotactic response protein; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). Acts on free CheY-P. Belongs to the CheZ family. (214 aa) |
| | ruvC | Holliday junction nuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (173 aa) |
| | exoX | DNA exonuclease X; Degrades ss and ds DNA with 3'-5' polarity; similar to E. coli orf, hypothetical protein (AAC74914.1); Blastp hit to AAC74914.1 (220 aa), 90% identity in aa 1 - 219. (232 aa) |
| | prpA | Serine/threonine protein phosphatase; Can hydrolyze phosphorylated Ser-, Thr- or Tyr-substrates in vitro. The natural substrate is unknown. (216 aa) |
| | STM1827 | Putative diguanylate cyclase/phosphodiesterase; Similar to E. coli orf, hypothetical protein (AAC74885.1); Blastp hit to AAC74885.1 (542 aa), 75% identity in aa 5 - 540. (567 aa) |
| | rnd | RNase D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (375 aa) |
| | pth | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Involved in lambda inhibition of host protein synthesis. PTH activity may, directly or indirectly, be the target for lambda bar RNA leading to rap cell death (By similarity). (202 aa) |
| | ychK | Putative phosphoesterase; Similar to E. coli orf, hypothetical protein (AAC74316.1); Blastp hit to AAC74316.1 (314 aa), 83% identity in aa 14 - 314. (301 aa) |
| | yciA | Putative Acyl-CoA hydrolase; Catalyzes the hydrolysis of the thioester bond in palmitoyl- CoA and malonyl-CoA. (133 aa) |
| | trpH | trpR controlled transcriptional unit in the 5' upstream region of the trp operon; Efficiently catalyzes the hydrolysis of the 3'-phosphate from 3',5'-bis-phosphonucleotides as well as the successive hydrolysis of 5'-phosphomononucleotides from the 5'-end of short pieces of RNA and DNA, with no specificity toward the identity of the nucleotide base. Is more efficient at hydrolyzing RNA oligonucleotides than DNA oligonucleotides. This enzyme can also hydrolyze annealed DNA duplexes, albeit at a catalytic efficiency lower than that of the corresponding single-stranded oligonucleotides. (293 aa) |
| | pgpB | Similar to E. coli non-essential phosphatidylglycerophosphate phosphatase, membrane bound (AAC74360.1); Blastp hit to AAC74360.1 (254 aa), 82% identity in aa 1 - 254. (254 aa) |
| | rnb | RNase II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction. (644 aa) |
| | ydaL | Putative Smr domain protein; Similar to E. coli orf, hypothetical protein (AAC74422.1); Blastp hit to AAC74422.1 (187 aa), 86% identity in aa 1 - 187. (187 aa) |
| | sseJ | Salmonella translocated effector; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is required for endosomal tubulation and negatively regulates the formation of Salmonella-induced filaments (Sifs) in epithelial cells. Has both deacylase and esterification activities in vitro, but esterification is probably the dominant activity in host cells. Significantly contributes to cholesterol esterification, which reduces cellular cholesterol in cells and abrogates the ability of SifA to associate with cholesterol and LAMP-1 v [...] (408 aa) |
| | STM0033 | Putative 5'-nucleotidase; Similar to E. coli UDP-sugar hydrolase (5'-nucleotidase) (AAC73582.1); Blastp hit to AAC73582.1 (550 aa), 26% identity in aa 1 - 253, 32% identity in aa 386 - 506; Belongs to the 5'-nucleotidase family. (523 aa) |
| | STM0035 | Similar to E. coli putative sulfatase (AAC76701.1); Blastp hit to AAC76701.1 (497 aa), 26% identity in aa 2 - 420. (497 aa) |
| | ileS | Isoleucine tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (944 aa) |
| | STM0084 | Similar to E. coli putative sulfatase (AAC76701.1); Blastp hit to AAC76701.1 (497 aa), 31% identity in aa 251 - 345, 31% identity in aa 5 - 103, 45% identity in aa 400 - 431. (629 aa) |
| | apaH | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (282 aa) |
| | polB | DNA polymerase II; 3'->5' exonuclease; similar to E. coli DNA polymerase II (AAC73171.1); Blastp hit to AAC73171.1 (783 aa), 89% identity in aa 1 - 783. (783 aa) |
| | STM0159 | Putative restriction endonuclease. (280 aa) |
| | ligT | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (176 aa) |
| | dgt | Deoxyguanosine triphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily. (505 aa) |
| | glnD | Uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (890 aa) |
| | rnhB | RNAse HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (198 aa) |
| | dnaE | DNA polymerase III, alpha subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase; Belongs to the DNA polymerase type-C family. DnaE subfamily. (1160 aa) |
| | yaeJ | putative-tRNA hydrolase domain protein; Similar to E. coli orf, hypothetical protein (AAC73302.1); Blastp hit to AAC73302.1 (140 aa), 85% identity in aa 1 - 136. (140 aa) |
| | proS | Proline tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves de [...] (572 aa) |
| | yaeD | Putative dehydratase; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position; Belongs to the GmhB family. (188 aa) |
| | gloB | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (251 aa) |
| | rnhA | RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (155 aa) |
| | dnaQ | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contains the editing function and is a proofreading 3'- 5' exonuclease (By similarity). (243 aa) |
| | STM0296 | Putative cytoplasmic protein. (82 aa) |
| | yafA | Putative hydrolase of the alpha/beta superfamily; Displays esterase activity toward pNP-butyrate. (414 aa) |
| | STM0343 | Putative diguanylate cyclase/phosphodiesterase domain 1; Similar to E. coli orf, hypothetical protein (AAC75237.1); Blastp hit to AAC75237.1 (518 aa), 31% identity in aa 10 - 512. (524 aa) |
| | res | DNA restriction (DNA helicase); Cleaves DNA some 25 base-pairs downstream from the recognition site. May also act as a helicase involved in unwinding DNA at the cleavage site. Protein only required for restriction but needs the presence of the modification enzyme; Belongs to the type III restriction-modification system res protein family. (990 aa) |
| | sbcC | ATP-dependent dsDNA exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SMC family. SbcC subfamily. (1046 aa) |
| | sbcD | ATP-dependent dsDNA exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (400 aa) |
| | phoR | Sensory kinase in two-component regulatory system with PhoB, regulates pho regulon; Similar to E. coli positive and negative sensor protein for pho regulon (AAC73503.1); Blastp hit to AAC73503.1 (431 aa), 90% identity in aa 1 - 431. (431 aa) |
| | yajB | Putative cytoplasmic protein; Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; Belongs to the AcpH family. (193 aa) |
| | yajD | Putative cytoplasmic protein; Hypothetical 12.6 Kda protein in secF-tsx intergenic region. (SW:YAJD_SALTY); Belongs to the HNH nuclease family. (115 aa) |
| | pgpA | Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (171 aa) |
| | xseB | Exonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (80 aa) |
| | ybaW | Putative esterase; Similar to E. coli orf, hypothetical protein (AAC73546.1); Blastp hit to AAC73546.1 (132 aa), 94% identity in aa 1 - 132. (132 aa) |
| | cof | Putative hydrolase; Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5- hydroxymethylpyrimidine phosphate (HMP-P). (272 aa) |
| | tesB | Similar to E. coli acyl-CoA thioesterase II (AAC73555.1); Blastp hit to AAC73555.1 (286 aa), 91% identity in aa 1 - 286. (286 aa) |
| | ylaB | Putative diguanylate cyclase/phosphodiesterase domain 2; Similar to E. coli orf, hypothetical protein (AAC73559.1); Blastp hit to AAC73559.1 (518 aa), 67% identity in aa 3 - 518. (516 aa) |
| | STM0479 | Putative transposase; Similar to E. coli orf, hypothetical protein (AAC75365.1); Blastp hit to AAC75365.1 (296 aa), 49% identity in aa 7 - 296. (311 aa) |
| | gpmB | Similar to E. coli phosphoglyceromutase 2 (AAC77348.1); Blastp hit to AAC77348.1 (215 aa), 91% identity in aa 1 - 215; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (215 aa) |
| | serB | Similar to E. coli 3-phosphoserine phosphatase (AAC77341.1); Blastp hit to AAC77341.1 (322 aa), 93% identity in aa 1 - 322. (322 aa) |
| | yjjV | Putative hydrolase; Similar to E. coli orf, hypothetical protein (AAC77331.1); Blastp hit to AAC77331.1 (211 aa), 76% identity in aa 1 - 210. (257 aa) |
| | yjjG | Putative haloacid dehalogenase-like hydrolase; Similar to E. coli putative phosphatase (AAC77327.1); Blastp hit to AAC77327.1 (225 aa), 91% identity in aa 1 - 225. (226 aa) |
| | holD | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. (145 aa) |
| | STM4549 | Putative cytoplasmic protein. (152 aa) |
| | mdoB | Phosphoglycerol transferase I; Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones; Belongs to the OpgB family. (750 aa) |
| | mrr | Similar to E. coli restriction of methylated adenine (AAC77307.1); Blastp hit to AAC77307.1 (304 aa), 77% identity in aa 1 - 304. (304 aa) |
| | hsdR | Host restriction; similar to E. coli host restriction; endonuclease R (AAC77306.1); Blastp hit to AAC77306.1 (1188 aa), 91% identity in aa 20 - 1188. (1169 aa) |
| | yjiW | Putative SOS response protein; Involved in the degradation and recycling of damaged RNA. It is itself a target for degradation by the ATP-dependent protease Lon. Belongs to the SymE family. (110 aa) |
| | STM4518 | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75304.1); Blastp hit to AAC75304.1 (299 aa), 45% identity in aa 187 - 277, 73% identity in aa 1 - 42, 36% identity in aa 216 - 295. (171 aa) |
| | STM4490 | Putative Mrr restriction endonuclease. (329 aa) |
| | valS | Valine tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (951 aa) |
| | STM4436 | Putative endonuclease. (294 aa) |
| | STM4427 | Putative endonuclease. (277 aa) |
| | fbp | Similar to E. coli fructose-bisphosphatase (AAC77189.1); Blastp hit to AAC77189.1 (332 aa), 97% identity in aa 1 - 332. (332 aa) |
| | cysQ | CysQ protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. (246 aa) |
| | cpdB | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; This bifunctional enzyme catalyzes two consecutive reactions during ribonucleic acid degradation. Converts a 2',3'-cyclic nucleotide to a 3'-nucleotide and then the 3'-nucleotide to the corresponding nucleoside and phosphate; Belongs to the 5'-nucleotidase family. (647 aa) |
| | yjfR | Putative Zn-dependent hydrolases of the beta-lactamase fold; Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3- keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions; Belongs to the UlaG family. (354 aa) |
| | vacB | Putative exoribonuclease; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. (812 aa) |
| | orn | Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (181 aa) |
| | phoN | Nonspecific acid phosphatase precursor. (SW:PHON_SALTY). (250 aa) |
| | yjdB | Putative integral membrane protein; Catalyzes the addition of a phosphoethanolamine moiety to the lipid A. The phosphoethanolamine modification is required for resistance to polymyxin; Belongs to the phosphoethanolamine transferase family. EptA subfamily. (547 aa) |
| | yjcC | Putative diguanylate cyclase/phosphodiesterase; Similar to E. coli orf, hypothetical protein (AAC77031.1); Blastp hit to AAC77031.1 (528 aa), 64% identity in aa 1 - 528. (533 aa) |
| | uvrA | DNA excision repair enzyme; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate; Belongs to the ABC transporter superfamily. UvrA family. (941 aa) |
| | aphA | Non-specific acid phosphatase/phosphotransferase, class B; Dephosphorylates several organic phosphate monoesters such as 3'-UMP, 5'-UMP and pNPP. Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoesters to free hydroxyl groups of various organic compounds such as the 2'-, 3-, or 5'-hydroxyls of nucleosides and nucleotides. Also displays significant phosphomutase activity since it is able to catalyze the transfer of the phosphate group of 3'-AMP from the 3'-position both to the 2'- and 5'-positions. One of the physio [...] (237 aa) |
| | aceK | Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (583 aa) |
| | nfi | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (223 aa) |
| | yijP | Putative integral membrane protein; Catalyzes the addition of a phosphoethanolamine moiety to the outer membrane lipopolysaccharide core; Belongs to the phosphoethanolamine transferase family. EptC/CptA subfamily. (577 aa) |
| | STM4104 | Putative 5'-nucleotidase; Related esterase; similar to E. coli UDP-sugar hydrolase (5'-nucleotidase) (AAC73582.1); Blastp hit to AAC73582.1 (550 aa), 25% identity in aa 34 - 253, 28% identity in aa 383 - 506; 2',3'-cyclic phosphodiesterase; Belongs to the 5'-nucleotidase family. (518 aa) |
| | glpX | Similar to E. coli unknown function in glycerol metabolism (AAC76907.1); Blastp hit to AAC76907.1 (336 aa), 94% identity in aa 1 - 336. (336 aa) |
| | STM4032 | Putative acetyl esterase; Similar to E. coli putative lipase (AAC73578.1); Blastp hit to AAC73578.1 (319 aa), 32% identity in aa 84 - 312. (309 aa) |
| | STM4031 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76118.1); Blastp hit to AAC76118.1 (104 aa), 40% identity in aa 1 - 99. (103 aa) |
| | yihZ | D-Tyr-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (145 aa) |
| | STM4013 | Putative membrane-associated metal-dependent hydrolase. (291 aa) |
| | STM4010 | Similar to E. coli putative phosphatase (AAC73853.1); Blastp hit to AAC73853.1 (272 aa), 44% identity in aa 147 - 267, 30% identity in aa 1 - 169. (244 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template. (928 aa) |
| | yihG | Similar to E. coli putative endonuclease (AAC76860.1); Blastp hit to AAC76860.1 (310 aa), 82% identity in aa 10 - 307. (302 aa) |
| | pepQ | Proline dipeptidase; Splits dipeptides with a prolyl residue in the C-terminal position. (443 aa) |
| | yigW | Putative hydrolase of PHP superfamily; 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair. Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily. (260 aa) |
| | dlhH | Putative dienelactone hydrolase family; Similar to E. coli putative enzyme (AAC76833.1); Blastp hit to AAC76833.1 (332 aa), 91% identity in aa 2 - 181. (270 aa) |
| | yigL | Putative hydrolase of the HAD superfamily; Similar to E. coli orf, hypothetical protein (AAC76829.1); Blastp hit to AAC76829.1 (171 aa), 85% identity in aa 1 - 167. (266 aa) |
| | pldB | Similar to E. coli lysophospholipase L(2) (AAC76828.1); Blastp hit to AAC76828.1 (340 aa), 81% identity in aa 1 - 336. (338 aa) |
| | pldA | Outer membrane phospholipase A; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities; Belongs to the phospholipase A1 family. (289 aa) |
| | yigI | Putative PaaI protein; Possibly involved in aromatic compounds catabolism; hypothetical protein in rarD-pldA intergenic region. (SW:YIGI_SALTY). (161 aa) |
| | yigB | Putative hydrolase of the HAD superfamily; Similar to E. coli putative phosphatase (AAC76815.1); Blastp hit to AAC76815.1 (238 aa), 87% identity in aa 1 - 238. (238 aa) |
| | rep | Rep helicase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (674 aa) |
| | rnpA | RNase P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (119 aa) |
| | dnaN | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (366 aa) |
| | yidA | Putative hydrolase of the HAD superfamily; Similar to E. coli orf, hypothetical protein (AAC76720.1); Blastp hit to AAC76720.1 (270 aa), 93% identity in aa 1 - 270. (281 aa) |
| | uhpB | Sensory histidine kinase in two-component regulatory sytem with UhpA; Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT. UhpB functions as a membrane-associated protein kinase that autophosphorylates in response to interaction with UhpC, and subsequently transfers its phosphate group to the response regulator UhpA. Can also dephosphorylate UhpA. (500 aa) |
| | STM3766 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75365.1); Blastp hit to AAC75365.1 (296 aa), 67% identity in aa 1 - 278, 45% identity in aa 216 - 296. (313 aa) |
| | spoT | (p)ppGpp synthetase II; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (703 aa) |
| | rph | RNase PH; Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates. (238 aa) |
| | yhjW | Putative membrane-associated metal-dependent hydrolase; Catalyzes the addition of a phosphoethanolamine (pEtN) moiety to the outer 3-deoxy-D-manno-octulosonic acid (Kdo) residue of a Kdo(2)-lipid A. Phosphatidylethanolamines with one unsaturated acyl group functions as pEtN donors and the reaction releases diacylglycerol. (563 aa) |
| | STM3595 | Putative phosphatase. (423 aa) |
| | ugpQ | Similar to E. coli glycerophosphodiester phosphodiesterase, cytosolic (AAC76474.1); Blastp hit to AAC76474.1 (247 aa), 87% identity in aa 1 - 244. (246 aa) |
| | STM3550 | Similar to E. coli putative hydrolase (AAC76404.1); Blastp hit to AAC76404.1 (292 aa), 28% identity in aa 24 - 289, 71% identity in aa 7 - 20. (344 aa) |
| | STM3516 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73329.1); Blastp hit to AAC73329.1 (92 aa), 78% identity in aa 1 - 91. (91 aa) |
| | bioH | Putative hydrolase; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. (256 aa) |
| | STM3508 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75365.1); Blastp hit to AAC75365.1 (296 aa), 67% identity in aa 1 - 296. (304 aa) |
| | yrfG | Similar to E. coli putative phosphatase (AAC76424.1); Blastp hit to AAC76424.1 (237 aa), 85% identity in aa 16 - 237. (222 aa) |
| | gph | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (252 aa) |
| | yheT | Contains alpha/beta-hydrolase fold; similar to E. coli orf, hypothetical protein (AAC76378.1); Blastp hit to AAC76378.1 (340 aa), 84% identity in aa 1 - 339. (355 aa) |
| | cafA | RNase G; Similar to E. coli bundles of cytoplasmic filaments (AAC76279.1); Blastp hit to AAC76279.1 (495 aa), 96% identity in aa 7 - 495. (489 aa) |
| | STM1623 | Putative carboxylesterase; Belongs to the type-B carboxylesterase/lipase family. (502 aa) |
| | yrbI | Putative protein of HAD superfamily; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. (188 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (211 aa) |
| | rnt | RNase T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (215 aa) |
| | orf32 | Putative hydrolase or acyltransferase; Proline iminopeptidase like protein (gi|1526980). (297 aa) |
| | menI | Putative protein PaaI; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA). (136 aa) |
| | STM1330 | Putative DNA/RNA non-specific endonuclease. (284 aa) |
| | ydiZ | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74794.1); Blastp hit to AAC74794.1 (96 aa), 69% identity in aa 1 - 94. (96 aa) |
| | cho | Putative nuclease subunit of the excinuclease complex; Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity). (302 aa) |
| | astE | Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate. (322 aa) |
| | xthA | Exonuclease III; Major apurinic-apyrimidinic endonuclease of E.coli. It removes the damaged DNA at cytosines and guanines by cleaving on the 3'-side of the AP site by a beta-elimination reaction. It exhibits 3'- 5'-exonuclease, 3'-phosphomonoesterase, 3'-repair diesterase and ribonuclease H activities (By similarity). (268 aa) |
| | yeaK | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74857.1); Blastp hit to AAC74857.1 (167 aa), 87% identity in aa 1 - 165. (172 aa) |
| | phoQ | Sensory kinase protein in two-component regulatory system with PhoP; Member of the two-component regulatory system PhoP/PhoQ which regulates the expression of genes involved in virulence, adaptation to acidic and low Mg(2+) environments and resistance to host defense antimicrobial peptides. Essential for intramacrophage survival of S.typhimurium. In low periplasmic Mg(2+), PhoQ functions as a membrane- associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of [...] (487 aa) |
| | ycfH | Putative metal-dependent hydrolase; Similar to E. coli orf, hypothetical protein (AAC74184.1); Blastp hit to AAC74184.1 (265 aa), 93% identity in aa 1 - 265. (265 aa) |
| | holB | Similar to E. coli DNA polymerase III, delta prime subunit (AAC74183.1); Blastp hit to AAC74183.1 (334 aa), 79% identity in aa 1 - 334. (334 aa) |
| | rne | RNase E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1067 aa) |
| | ycdX | Putative Histidinol phosphatase; Related to hydrolases of the PHP family; similar to E. coli orf, hypothetical protein (AAC74118.1); Blastp hit to AAC74118.1 (245 aa), 89% identity in aa 1 - 245. (245 aa) |
| | agp | Glucose-1-phosphatase precursor. (SW:AGP_SALTY). (413 aa) |
| | STM1109 | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75328.1); Blastp hit to AAC75328.1 (311 aa), 27% identity in aa 7 - 147, 27% identity in aa 155 - 277. (312 aa) |
| | sopB | Pathogenicity island encoded protein: SPI5; Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulti [...] (561 aa) |
| | STM1031 | Gifsy-2 prophage protein. (712 aa) |
| | STM1009 | Gifsy-2 prophage exodeoxyribonuclease; Exodeoxyribonuclease VIII homolog (gi|7467238). (961 aa) |
| | tnpA_1 | IS200 transposase; Involved in the transposition of the insertion sequence. (152 aa) |
| | STM0910 | Fels-1 prophage protein. (702 aa) |
| | STM0886 | Similar to E. coli putative sulfatase (AAC76701.1); Blastp hit to AAC76701.1 (497 aa), 25% identity in aa 7 - 358, 26% identity in aa 401 - 446. (495 aa) |
| | STM0867 | Putative hydrolase; Similar to E. coli orf, hypothetical protein (AAC73931.1); Blastp hit to AAC73931.1 (262 aa), 82% identity in aa 1 - 261. (271 aa) |
| | ybiV(1) | Putative hydrolase of the HAD superfamily; Similar to E. coli orf, hypothetical protein (AAC73909.1); Blastp hit to AAC73909.1 (271 aa), 88% identity in aa 1 - 269. (269 aa) |
| | ybiV(2) | Putative hydrolase of the HAD superfamily; Similar to E. coli orf, hypothetical protein (AAC73909.1); Blastp hit to AAC73909.1 (271 aa), 94% identity in aa 33 - 269. (239 aa) |
| | ybiP | Putative integral membrane protein; Similar to E. coli putative enzyme (AAC73902.1); Blastp hit to AAC73902.1 (527 aa), 84% identity in aa 1 - 526. (526 aa) |
| | uvrB | UvrB with UvrAC is a DNA excision repair enzyme; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA [...] (673 aa) |
