STRINGSTRING
nuoL nuoL nuoM nuoM nuoN nuoN elaB elaB rcsC rcsC yojI yojI ccmF ccmF yehZ yehZ uraA uraA STM2503 STM2503 yfgM yfgM yfgA yfgA yfhB yfhB lepB lepB yfiK yfiK STM2690 STM2690 iroC iroC iroN iroN gabP gabP ygaP ygaP proV proV proW proW proX proX emrA emrA sitB sitB sitC sitC sitD sitD STM2986 STM2986 lgt lgt araE araE ygfX ygfX yggE yggE yggB yggB STM3074 STM3074 STM3075 STM3075 STM3142 STM3142 exbD exbD yghB yghB tolC tolC ygiM ygiM bacA bacA yrbD yrbD yrbE yrbE yrbK yrbK yhbG yhbG yhdP yhdP acrE acrE mscL mscL kefB kefB yheR yheR yhfC yhfC envZ envZ glpG glpG ugpC ugpC ugpE ugpE ugpA ugpA ugpB ugpB yhiP yhiP STM3631 STM3631 mtlA mtlA yicE yicE STM3769 STM3769 STM3771 STM3771 STM3772 STM3772 uhpC uhpC STM3792 STM3792 emrD emrD ccmF-2 ccmF-2 yidD yidD pstC pstC rbsA rbsA rarD rarD pldA pldA rthB rthB tatA tatA tatB tatB trkH trkH yshA yshA yiiY yiiY cpxA cpxA ego ego yneA yneA STM4102 STM4102 argH argH btuB btuB secE secE hydH hydH malG malG malF malF malE malE malK malK lamB lamB STM4259 STM4259 yjcG yjcG fxsA fxsA frdD frdD hflK hflK hflC hflC yjeT yjeT ytfM ytfM cysU cysU yjgQ yjgQ STM4495 STM4495 STM4535 STM4535 STM4536 STM4536 STM4537 STM4537 ytjA ytjA yjgP yjgP cysW cysW cysA cysA cysZ cysZ nupC nupC nuoA nuoA nuoB nuoB nuoE nuoE nuoG nuoG nuoH nuoH nuoI nuoI nuoJ nuoJ nuoK nuoK yehX yehX mdtA mdtA wza wza wzc wzc cbiM cbiM cbiN cbiN cboQ cboQ cbiO cbiO ompS ompS motA motA motB motB znuC znuC STM1849 STM1849 yebS yebS htpX htpX manZ manZ manY manY manX manX STM1788 STM1788 STM1741 STM1741 yciB yciB pgpB pgpB yciS yciS zntB zntB STM1653 STM1653 yncD yncD yddG yddG STM1545 STM1545 STM1537 STM1537 STM1530 STM1530 ydeD ydeD osmY-2 osmY-2 osmX osmX osmV osmV clcB clcB pntB pntB pntA pntA ompN ompN ydgR ydgR ydiS ydiS ydiT ydiT btuD btuD btuC btuC sppA sppA potA potA potB potB potC potC ycfU ycfU ptsG ptsG mviN mviN yceE yceE mdoH mdoH csgE csgE csgF csgF csgG csgG STM1131 STM1131 putP putP yccA yccA ompA ompA pqiA pqiA ompF ompF msbA msbA focA focA ycaD ycaD ftsK ftsK cydD cydD cydC cydC ybjZ ybjZ ybjY ybjY potI potI potH potH potG potG STM0858 STM0858 ybhS ybhS ybhR ybhR modF modF tolA tolA tolR tolR tolQ tolQ STM0723 STM0723 STM0707 STM0707 kdpA kdpA kdpB kdpB kdpC kdpC lnt lnt ybeV ybeV ybeS ybeS kdgT2 kdgT2 dacA dacA crcB crcB fepA fepA STM0577 STM0577 STM0576 STM0576 STM0575 STM0575 STM0574 STM0574 STM0562 STM0562 sfbC sfbC sfbB sfbB STM0509 STM0509 ybbM ybbM amtB amtB cypD cypD cyoC cyoC cyoD cyoD yajR yajR phnT phnT phnU phnU pgpA pgpA tsx tsx yajC yajC phoR phoR STM0382 STM0382 sbmA sbmA STM0352 STM0352 pagN pagN abc abc yaeE yaeE yaeC yaeC fhuB fhuB fhuC fhuC folK folK yadI yadI gcd gcd kdgT kdgT aroP aroP ftsQ ftsQ ftsW ftsW ftsL ftsL kefC kefC yabF yabF fixX fixX fixC fixC lspA lspA nhaA nhaA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nuoLSimilar to E. coli NADH dehydrogenase I chain L (AAC75338.1); Blastp hit to AAC75338.1 (613 aa), 94% identity in aa 1 - 613. (613 aa)
nuoMSimilar to E. coli NADH dehydrogenase I chain M (AAC75337.1); Blastp hit to AAC75337.1 (509 aa), 96% identity in aa 1 - 509. (509 aa)
nuoNNADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (425 aa)
elaBPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75326.1); Blastp hit to AAC75326.1 (101 aa), 89% identity in aa 1 - 101. (103 aa)
rcsCSensory histidine kinase in two-component regulatory system with RcsB; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (948 aa)
yojIATPase component; similar to E. coli putative ATP-binding component of a transport system (AAC75271.1); Blastp hit to AAC75271.1 (547 aa), 90% identity in aa 1 - 547. (547 aa)
ccmFSimilar to E. coli cytochrome c-type biogenesis protein (AAC75256.1); Blastp hit to AAC75256.1 (647 aa), 85% identity in aa 1 - 646. (643 aa)
yehZPutative ABC superfamily transport protein (bind_prot); Possibly glycine betaine choline transport for osmoprotection; similar to E. coli putative transport system permease protein (AAC75192.1); Blastp hit to AAC75192.1 (305 aa), 88% identity in aa 1 - 305. (305 aa)
uraANCS2 family uracil transport protein; Similar to E. coli uracil transport (AAC75550.1); Blastp hit to AAC75550.1 (429 aa), 94% identity in aa 1 - 425. (429 aa)
STM2503Putative diguanylate cyclase; Similar to E. coli putative cytochrome C-type biogenesis protein (AAC75556.1); Blastp hit to AAC75556.1 (747 aa), 73% identity in aa 1 - 733. (737 aa)
yfgMPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75566.1); Blastp hit to AAC75566.1 (206 aa), 88% identity in aa 1 - 206. (206 aa)
yfgAPutative membrane protein; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis. (334 aa)
yfhBPutatative phosphoserine phosphatase; Similar to E. coli orf, hypothetical protein (AAC75613.1); Blastp hit to AAC75613.1 (190 aa), 91% identity in aa 1 - 190. (211 aa)
lepBLeader peptidase (signal peptidase I), serine protease; Signal peptidase I. (SW:LEP_SALTY); Belongs to the peptidase S26 family. (324 aa)
yfiKPutative transport protein; Exporter of O-acetylserine (OAS) and cysteine; Belongs to the Rht family. (195 aa)
STM2690Putative outer membrane efflux protein; Similar to E. coli putative resistance protein (AAC73673.1); Blastp hit to AAC73673.1 (457 aa), 24% identity in aa 67 - 450. (469 aa)
iroCPutative ATP binding cassette (ABC) transporter; Similar to E. coli ATP-binding transport protein; multicopy suppressor of htrB (AAC74000.1); Blastp hit to AAC74000.1 (582 aa), 26% identity in aa 14 - 582, 29% identity in aa 34 - 565. (1217 aa)
iroNTonB-dependent siderophore receptor protein; Similar to E. coli outer membrane receptor for ferric enterobactin (enterochelin) and colicins B and D (AAC73685.1); Blastp hit to AAC73685.1 (746 aa), 52% identity in aa 3 - 728, 44% identity in aa 245 - 746. (726 aa)
gabPAPC family; similar to E. coli transport permease protein of gamma-aminobutyrate (AAC75710.1); Blastp hit to AAC75710.1 (466 aa), 92% identity in aa 1 - 466. (466 aa)
ygaPPutative rhodanese-related sulfurtransferase; Similar to E. coli orf, hypothetical protein (AAC75715.1); Blastp hit to AAC75715.1 (174 aa), 75% identity in aa 1 - 173. (175 aa)
proVGlycine/betaine/proline transport protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for energy coupling to the transport system. (400 aa)
proWGlycine/betaine/proline transport protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (354 aa)
proXGlycine/betaine/proline transport protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Binds glycine betaine and proline betaine with high affinity. (331 aa)
emrASimilar to E. coli multidrug resistance secretion protein (AAC75732.1); Blastp hit to AAC75732.1 (390 aa), 89% identity in aa 1 - 390. (390 aa)
sitBFur regulated Salmonella iron transporter; SitB (gi|5231095). (273 aa)
sitCFur regulated Salmonella iron transporter; SitC (gi|5231096). (286 aa)
sitDFur regulated Salmonella iron transporter; SitD (gi|5231097). (282 aa)
STM2986Putative integral membrane protein; Similar to E. coli orf, hypothetical protein (AAC76822.1); Blastp hit to AAC76822.1 (300 aa), 31% identity in aa 25 - 294. (295 aa)
lgtPhosphatidylglycerol-prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins. (291 aa)
araEL-arabinose: proton symport protein; Low-affinity transporter;MFS family; similar to E. coli low-affinity L-arabinose transport system proton symport protein (AAC75880.1); Blastp hit to AAC75880.1 (472 aa), 97% identity in aa 1 - 472; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (472 aa)
ygfXPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75934.1); Blastp hit to AAC75934.1 (135 aa), 83% identity in aa 1 - 131. (137 aa)
yggEPutative periplasmic immunogenic protein; Similar to E. coli putative actin (AAC75959.1); Blastp hit to AAC75959.1 (246 aa), 88% identity in aa 1 - 245. (248 aa)
yggBPutative membrane protein; Involved in stability of MscS mechanosensitive channel; similar to E. coli putative transport protein (AAC75961.1); Blastp hit to AAC75961.1 (286 aa), 91% identity in aa 1 - 285. (286 aa)
STM3074Putative ABC-type cobalt transport system; ATPase component; similar to E. coli ATP-binding component of putrescine transport system (AAC73942.1); Blastp hit to AAC73942.1 (404 aa), 38% identity in aa 74 - 207. (225 aa)
STM3075Putative ABC-type cobalt transport system; ATPase component; similar to E. coli ATP-binding component of sulfate permease A protein; chromate resistance (AAC75475.1); Blastp hit to AAC75475.1 (365 aa), 33% identity in aa 18 - 219. (218 aa)
STM3142Putative ferrichrome-binding periplasmic protein. (350 aa)
exbDtonB-dependent uptake of B colicins; similar to E. coli uptake of enterochelin; tonB-dependent uptake of B colicins (AAC76041.1); Blastp hit to AAC76041.1 (141 aa), 93% identity in aa 1 - 141. (141 aa)
yghBPutative DedA family membrane protein; Hypothetical protein in metC 3'region. (SW:YGHB_SALTY). (219 aa)
tolCOuter membrane channel; Specific tolerance to colicin E1; segregation of daughter chromosomes; role in organic solvent tolerance; similar to E. coli outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (AAC76071.1); Blastp hit to AAC76071.1 (495 aa), 89% identity in aa 1 - 495. (491 aa)
ygiMPutative SH3 domain protein; Similar to E. coli orf, hypothetical protein (AAC76091.1); Blastp hit to AAC76091.1 (206 aa), 91% identity in aa 1 - 206. (204 aa)
bacABacitracin resistance; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (274 aa)
yrbDPutative ABC superfamily transport protein; Bind_prot; similar to E. coli orf, hypothetical protein (AAC76225.1); Blastp hit to AAC76225.1 (183 aa), 87% identity in aa 1 - 183. (183 aa)
yrbEPutative ABC superfamily transport protein; Membr; similar to E. coli orf, hypothetical protein (AAC76226.1); Blastp hit to AAC76226.1 (260 aa), 96% identity in aa 1 - 260. (260 aa)
yrbKPutative inner membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. (191 aa)
yhbGPutative ABC superfamily transport protein; Atp_bind; similar to E. coli putative ATP-binding component of a transport system (AAC76233.1); Blastp hit to AAC76233.1 (241 aa), 98% identity in aa 1 - 241. (241 aa)
yhdPPutative protease; Similar to E. coli orf, hypothetical protein (AAC76277.1); Blastp hit to AAC76277.1 (986 aa), 80% identity in aa 1 - 986. (1266 aa)
acrESimilar to E. coli transmembrane protein affects septum formation and cell membrane permeability (AAC76297.1); Blastp hit to AAC76297.1 (385 aa), 88% identity in aa 1 - 380; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (385 aa)
mscLMechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (137 aa)
kefBCPA2 family K+:H+ antiporter; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (601 aa)
yheRPutative NAD(P)H oxidoreductase; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB. (183 aa)
yhfCPutative MFS family transport protein; Similar to E. coli putative transport (AAC76389.1); Blastp hit to AAC76389.1 (393 aa), 90% identity in aa 1 - 393. (393 aa)
envZSensory histidine kinase in two-component regulatory system with OmpR; Member of the two-component regulatory system EnvZ/OmpR involved in osmoregulation (particularly of genes ompF and ompC) as well as other genes (By similarity). EnvZ functions as a membrane- associated protein kinase that phosphorylates OmpR in response to environmental signals; at low osmolarity OmpR activates ompF transcription, while at high osmolarity it represses ompF and activates ompC transcription (By similarity). (450 aa)
glpGProtein of glp regulon; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. (276 aa)
ugpCSn-glycerol 3-phosphate transport protein; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system (Probable); Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (356 aa)
ugpESn-glycerol 3-phosphate transport protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (281 aa)
ugpASn-glycerol 3-phosphate transport protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (295 aa)
ugpBSn-glycerol 3-phosphate transport protein; sn-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system UgpACE. (438 aa)
yhiPPutative POT family peptide transport protein; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily. (489 aa)
STM3631Similar to E. coli putative permease (AAC75926.1); Blastp hit to AAC75926.1 (505 aa), 27% identity in aa 54 - 466. (441 aa)
mtlASimilar to E. coli PTS system, mannitol-specific enzyme IIABC components (AAC76623.1); Blastp hit to AAC76623.1 (637 aa), 95% identity in aa 1 - 637. (638 aa)
yicESimilar to E. coli putative transport protein (AAC76678.1); Blastp hit to AAC76678.1 (463 aa), 95% identity in aa 1 - 462. (463 aa)
STM3769Putative phosphotransferase system enzyme II; Similar to E. coli PTS enzyme IID, mannose-specific (AAC74889.1); Blastp hit to AAC74889.1 (286 aa), 39% identity in aa 16 - 286. (286 aa)
STM3771Putative phosphotransferase system enzyme IIB; Similar to E. coli PTS enzyme IIAB, mannose-specific (AAC74887.1); Blastp hit to AAC74887.1 (323 aa), 29% identity in aa 164 - 320. (161 aa)
STM3772Putative phosphotransferase system enzyme IIA. (141 aa)
uhpCRegulator of uhpT expression; Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT. UhpC senses external glucose-6-phosphate and interacts with the histidine kinase UhpB, leading to the stimulation of the autokinase activity of UhpB. Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family. (442 aa)
STM3792Putative L-fucose permease; Similar to E. coli fucose permease (AAC75843.1); Blastp hit to AAC75843.1 (438 aa), 34% identity in aa 17 - 428. (438 aa)
emrDMFS family multidrug tranport protein; Similar to E. coli 2-module integral membrane pump; multidrug resistance (AAC76696.1); Blastp hit to AAC76696.1 (396 aa), 92% identity in aa 3 - 396. (394 aa)
ccmF-2Similar to E. coli cytochrome c-type biogenesis protein (AAC75256.1); Blastp hit to AAC75256.1 (647 aa), 85% identity in aa 1 - 646. (643 aa)
yidDPutative inner membrane protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (85 aa)
pstCHigh-affinity phosphate transporter; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (319 aa)
rbsAD-ribose high-affinity transport protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (501 aa)
rarDChloramphenicol resistance; Similar to E. coli orf, hypothetical protein (AAC76822.1); Blastp hit to AAC76822.1 (300 aa), 83% identity in aa 8 - 297. (294 aa)
pldAOuter membrane phospholipase A; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities; Belongs to the phospholipase A1 family. (289 aa)
rthBHomoserine/homoserine lactone efflux protein; Conducts the efflux of homoserine and homoserine lactone. Belongs to the Rht family. (206 aa)
tatAComponent of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (84 aa)
tatBComponent of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (182 aa)
trkHTrk family potassium transport protein; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA and requires TrkE for transport activity (By similarity); Belongs to the TrkH potassium transport family. (483 aa)
yshAPutative outer membrane protein; Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is unknown (By similarity); Belongs to the oligogalacturonate-specific porin KdgM (TC 1.B.35) family. OmpL subfamily. (230 aa)
yiiYPutative outer membrane protein; Hypothetical 15.6 Kda protein in RHAT 5'region. (SW:YIIY_SALTY). (227 aa)
cpxASensory kinase in two-component regulatory system with CpxR; Senses misfolded proteins in bacterial envelope; similar to E. coli probable sensor protein (histidine protein kinase), acting on arcA (AAC76893.1); Blastp hit to AAC76893.1 (457 aa), 96% identity in aa 1 - 457. (457 aa)
egoPutative ABC-type sugar aldose transport system; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system (Probable). (511 aa)
yneAPutative sugar transport protein; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (Probable); Belongs to the bacterial solute-binding protein 2 family. (340 aa)
STM4102Similar to E. coli putative transport protein (AAC75961.1); Blastp hit to AAC75961.1 (286 aa), 54% identity in aa 1 - 281. (285 aa)
argHSimilar to E. coli argininosuccinate lyase (AAC76942.1); Blastp hit to AAC76942.1 (457 aa), 94% identity in aa 1 - 456. (458 aa)
btuBOuter membrane receptor for transport of vitamin B12, E colicins, and bacteriophage BF23; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (614 aa)
secEPreprotein translocase IISP family, membrane subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (127 aa)
hydHSensory kinase in two component regulatory system with HydG; Member of the two-component regulatory system ZraS/ZraR. May function as a membrane-associated protein kinase that phosphorylates ZraR in response to high concentrations of zinc or lead in the medium (By similarity). (465 aa)
malGMaltose transport protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. (296 aa)
malFMaltose transport protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. (514 aa)
malEMaltose transport protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. (399 aa)
malKMaltose transport protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (369 aa)
lamBPhage lambda receptor protein; Involved in the transport of maltose and maltodextrins. Does not act as a receptor for phages; Belongs to the porin LamB (TC 1.B.3) family. (452 aa)
STM4259ABC exporter outer membrane component homolog (gi|7467234). (439 aa)
yjcGPutative SSS family transport protein; Transports acetate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (549 aa)
fxsASuppresses F exclusion of bacteriophage T7; Similar to E. coli orf, hypothetical protein (AAC77100.1); Blastp hit to AAC77100.1 (125 aa), 92% identity in aa 1 - 125. (171 aa)
frdDFumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (119 aa)
hflKComponent of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could encode or regulate a protease. (419 aa)
hflCComponent of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could regulate a protease. (334 aa)
yjeTPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77133.1); Blastp hit to AAC77133.1 (65 aa), 89% identity in aa 1 - 65. (65 aa)
ytfMPutative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC77177.1); Blastp hit to AAC77177.1 (577 aa), 90% identity in aa 3 - 577. (577 aa)
cysUThiosulfate transport protein; Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane (By similarity). (277 aa)
yjgQPutative permease; Similar to E. coli orf, hypothetical protein (AAC77219.1); Blastp hit to AAC77219.1 (361 aa), 97% identity in aa 2 - 361. (360 aa)
STM4495Putative type II restriction enzyme, methylase subunit. (1225 aa)
STM4535Putative PTS permease; Similar to E. coli PTS enzyme IIAB, mannose-specific (AAC74887.1); Blastp hit to AAC74887.1 (323 aa), 22% identity in aa 6 - 127. (140 aa)
STM4536Putative PTS permease; Similar to E. coli PTS enzyme IIAB, mannose-specific (AAC74887.1); Blastp hit to AAC74887.1 (323 aa), 30% identity in aa 162 - 311. (153 aa)
STM4537Putative PTS permease; Similar to E. coli PTS system N-acetylgalactosamine-specific IIC component 1 (AAC76173.1); Blastp hit to AAC76173.1 (267 aa), 31% identity in aa 6 - 263. (259 aa)
ytjAPutative inner membrane protein. (59 aa)
yjgPPutative permease; Similar to E. coli orf, hypothetical protein (AAC77218.1); Blastp hit to AAC77218.1 (366 aa), 94% identity in aa 1 - 366. (366 aa)
cysWThiosulfate permease W protein; ABC superfamily (membrane); similar to E. coli sulfate transport system permease W protein (AAC75476.1); Blastp hit to AAC75476.1 (149 aa), 99% identity in aa 1 - 149. (291 aa)
cysASulfate permease A protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (365 aa)
cysZRequired for sulfate transport; Possibly involved in sulfate transport. (253 aa)
nupCNUP family nucleoside transport protein; Similar to E. coli permease of transport system for 3 nucleosides (AAC75452.1); Blastp hit to AAC75452.1 (400 aa), 98% identity in aa 1 - 400; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (400 aa)
nuoANADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (147 aa)
nuoBNADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (220 aa)
nuoENADH dehydrogenase I chain E; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 24 kDa subunit family. (166 aa)
nuoGNADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity). (910 aa)
nuoHNADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (325 aa)
nuoINADH dehydrogenase I chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa)
nuoJNADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa)
nuoKNADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa)
yehXPutative ABC-type proline/glycine betaine transport system, ATPase component; Similar to E. coli putative ATP-binding component of a transport system (AAC75190.1); Blastp hit to AAC75190.1 (308 aa), 87% identity in aa 1 - 307. (315 aa)
mdtAPutative HlyD family secretion protein; Similar to E. coli putative membrane protein (AAC75135.1); Blastp hit to AAC75135.1 (464 aa), 82% identity in aa 50 - 464; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (413 aa)
wzaPutative polysaccharide export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. (379 aa)
wzcPutative tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium (By similarity). Belongs to the etk/wzc family. (719 aa)
cbiMSynthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. (245 aa)
cbiNSynthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity; Belongs to the CbiN family. (93 aa)
cboQSynthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity; Belongs to the CbiQ family. (225 aa)
cbiOSynthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family. (271 aa)
ompSSimilar to E. coli putative outer membrane protein (AAC74459.1); Blastp hit to AAC74459.1 (377 aa), 71% identity in aa 1 - 236, 60% identity in aa 174 - 377; Belongs to the Gram-negative porin family. (398 aa)
motAProton conductor component of motor; MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity). (295 aa)
motBEnables flagellar motor rotation; MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque-generating machinery to the cell wall (By similarity). (309 aa)
znuCABC superfamily high affinity Zn transport protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system (Probable). Seems to be important for the virulence. (268 aa)
STM1849Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74904.1); Blastp hit to AAC74904.1 (879 aa), 90% identity in aa 1 - 879. (879 aa)
yebSPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74903.1); Blastp hit to AAC74903.1 (427 aa), 85% identity in aa 1 - 427. (427 aa)
htpXHeat shock protein; Integral membrane protein; similar to E. coli heat shock protein, integral membrane protein (AAC74899.1); Blastp hit to AAC74899.1 (293 aa), 96% identity in aa 1 - 293; Belongs to the peptidase M48B family. (293 aa)
manZMannose-specific enzyme IID; Sugar Specific PTS family; similar to E. coli PTS enzyme IID, mannose-specific (AAC74889.1); Blastp hit to AAC74889.1 (286 aa), 92% identity in aa 1 - 285. (286 aa)
manYMannose-specific enzyme IIC; Sugar Specific PTS family; similar to E. coli PTS enzyme IIC, mannose-specific (AAC74888.1); Blastp hit to AAC74888.1 (266 aa), 94% identity in aa 1 - 266. (266 aa)
manXMannose-specific enzyme IIAB; Sugar Specific PTS family; similar to E. coli PTS enzyme IIAB, mannose-specific (AAC74887.1); Blastp hit to AAC74887.1 (323 aa), 95% identity in aa 1 - 323. (322 aa)
STM1788Similar to E. coli probable Ni/Fe-hydrogenase 1 b-type cytochrome subunit (AAC74059.1); Blastp hit to AAC74059.1 (235 aa), 83% identity in aa 6 - 235. (243 aa)
STM1741Putative voltage-gated potassium channel. (278 aa)
yciBPutative intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. (179 aa)
pgpBSimilar to E. coli non-essential phosphatidylglycerophosphate phosphatase, membrane bound (AAC74360.1); Blastp hit to AAC74360.1 (254 aa), 82% identity in aa 1 - 254. (254 aa)
yciSPutative inner membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (102 aa)
zntBPutative Zn transport protein; Mediates efflux of zinc ions. (327 aa)
STM1653Putative membrane transporter of cations; Similar to E. coli methylviologen resistance (AAC73644.1); Blastp hit to AAC73644.1 (110 aa), 59% identity in aa 5 - 110. (112 aa)
yncDSimilar to E. coli putative outer membrane receptor for iron transport (AAC74533.1); Blastp hit to AAC74533.1 (700 aa), 84% identity in aa 1 - 700. (706 aa)
yddGPutative permease; Similar to E. coli orf, hypothetical protein (AAD13437.1); Blastp hit to AAD13437.1 (293 aa), 85% identity in aa 20 - 292. (274 aa)
STM1545Putative multidrug efflux protein; Similar to E. coli putative DEOR-type transcriptional regulator (AAC73932.1); Blastp hit to AAC73932.1 (402 aa), 23% identity in aa 26 - 394. (413 aa)
STM1537Similar to E. coli probable Ni/Fe-hydrogenase 1 b-type cytochrome subunit (AAC74059.1); Blastp hit to AAC74059.1 (235 aa), 54% identity in aa 1 - 222. (247 aa)
STM1530Similar to E. coli putative outer membrane protein (AAC74459.1); Blastp hit to AAC74459.1 (377 aa), 61% identity in aa 2 - 377; Belongs to the Gram-negative porin family. (372 aa)
ydeDPutative permease, integral membrane protein; May be an export pump for several amino acids and their metabolites, including cysteine; Belongs to the EamA transporter family. (300 aa)
osmY-2ABC-type transport system protein; Part of the OsmU ABC transporter complex, which is involved in the uptake of osmoprotectants such as choline-O-sulfate and glycine betaine. Probably responsible for the translocation of the substrate across the membrane. (236 aa)
osmXPutative periplasmic component; Part of the OsmU ABC transporter complex, which is involved in the uptake of osmoprotectants such as choline-O-sulfate and glycine betaine. (300 aa)
osmVABC-type proline/glycine betaine transport system; Part of the OsmU ABC transporter complex, which is involved in the uptake of osmoprotectants such as choline-O-sulfate and glycine betaine. Probably responsible for energy coupling to the transport system. (382 aa)
clcBPutative chloride channel protein; Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response; Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily. (429 aa)
pntBPyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (462 aa)
pntAPyridine nucleotide transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. (509 aa)
ompNOuter membrane protein N; Non-specific porin; similar to E. coli putative outer membrane protein (AAC74459.1); Blastp hit to AAC74459.1 (377 aa), 81% identity in aa 1 - 377. (377 aa)
ydgRPutative POT family peptide transport protein; Proton-dependent permease that transports di- and tripeptides. (501 aa)
ydiSFlavoprotein; Part of an electron transfer system. Belongs to the ETF-QO/FixC family. (428 aa)
ydiTPutative ferredoxin; Could be a 3Fe-4S cluster-containing protein. (97 aa)
btuDVitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (249 aa)
btuCVitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. (326 aa)
sppAProtease IV; Signal peptide peptidase; similar to E. coli protease IV, a signal peptide peptidase (AAC74836.1); Blastp hit to AAC74836.1 (618 aa), 86% identity in aa 1 - 618. (618 aa)
potASpermidine/putrescine transporter; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa)
potBSpermidine/putrescine transporter; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (287 aa)
potCSpermidine/putrescine transporter; ABC superfamily (membrane); similar to E. coli spermidine/putrescine transport system permease (AAC74208.1); Blastp hit to AAC74208.1 (264 aa), 96% identity in aa 1 - 258. (259 aa)
ycfUIntegral membrane protein ABC transporter; Similar to E. coli orf, hypothetical protein (AAC74200.1); Blastp hit to AAC74200.1 (399 aa), 93% identity in aa 1 - 399. (436 aa)
ptsGGlucose-specific IIBC component of the Sugar Specific PTS family; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. Also functions as a chemoreceptor monitoring the environment for changes in sugar concentration. It can also phosphorylate mannose, methyl alpha-glucoside and 2-deoxy-glucose. (477 aa)
mviNPutative virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (524 aa)
yceESimilar to E. coli putative transport protein (AAC74137.1); Blastp hit to AAC74137.1 (408 aa), 27% identity in aa 1 - 404. (404 aa)
mdoHMembrane glycosyltransferase; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (847 aa)
csgECurli production assembly/transport component, 2nd curli operon; May be involved in the biogenesis of curli organelles. (131 aa)
csgFCurli production assembly/transport component, 2nd curli operon; May be involved in the biogenesis of curli organelles. (138 aa)
csgGPutative transcriptional regulator in curly assembly/transport, 2nd curli operon; May be involved in the biogenesis of curli organelles; Belongs to the CsgG family. (277 aa)
STM1131Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC77267.1); Blastp hit to AAC77267.1 (241 aa), 26% identity in aa 4 - 239. (230 aa)
putPSSS family major sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (502 aa)
yccASimilar to E. coli putative carrier/transport protein (AAC74056.1); Blastp hit to AAC74056.1 (219 aa), 94% identity in aa 1 - 219; Belongs to the BI1 family. (219 aa)
ompAPutative membrane component hydrogenase; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. (350 aa)
pqiASimilar to E. coli paraquat-inducible protein A (AAC74036.1); Blastp hit to AAC74036.1 (417 aa), 89% identity in aa 1 - 417. (417 aa)
ompFOuter membrane protein 1a (ia;b;f), porin; Forms pores that allow passive diffusion of small molecules across the outer membrane. It is also a receptor for the bacteriophage T2 (By similarity). (363 aa)
msbAMulticopy repressor of htrB transport protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family. (582 aa)
focAFormate channel 1; putative FNT family member; similar to E. coli probable formate transporter (formate channel 1) (AAC73990.1); Blastp hit to AAC73990.1 (285 aa), 95% identity in aa 1 - 285. (285 aa)
ycaDPutative MFS family transport protein; Similar to E. coli putative transport (AAC73984.1); Blastp hit to AAC73984.1 (382 aa), 88% identity in aa 1 - 382. (382 aa)
ftsKCell division protein; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA trans [...] (1351 aa)
cydDCytochrome-related transporter; Zn sensitive; ABC superfamily (atp&memb); similar to E. coli ATP-binding component of cytochrome-related transport, Zn sensitive (AAC73973.1); Blastp hit to AAC73973.1 (588 aa), 90% identity in aa 1 - 588. (588 aa)
cydCCytochrome-related transporter; ABC superfamily (atp&memb); similar to E. coli ATP-binding component of cytochrome-related transport (AAC73972.1); Blastp hit to AAC73972.1 (573 aa), 86% identity in aa 1 - 573. (573 aa)
ybjZPutative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (648 aa)
ybjYSimilar to E. coli putative membrane protein (AAC73965.1); Blastp hit to AAC73965.1 (380 aa), 83% identity in aa 12 - 378; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (372 aa)
potIPutrescine transporter; ABC superfamily (membrane); similar to E. coli putrescine transport protein; permease (AAC73944.1); Blastp hit to AAC73944.1 (281 aa), 94% identity in aa 1 - 281. (281 aa)
potHPutrescine transporter; ABC superfamily (membrane); similar to E. coli putrescine transport protein; permease (AAC73943.1); Blastp hit to AAC73943.1 (317 aa), 92% identity in aa 1 - 317. (317 aa)
potGPutrescine transporter; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (377 aa)
STM0858Putative dehydrogenase (flavoproteins); Accepts electrons from ETF and reduces ubiquinone. (561 aa)
ybhSPutative ABC superfamily (membrane) transport protein; Similar to E. coli orf, hypothetical protein (AAC73880.1); Blastp hit to AAC73880.1 (377 aa), 94% identity in aa 6 - 377. (376 aa)
ybhRPutative ABC superfamily (membrane) transport protein; Similar to E. coli orf, hypothetical protein (AAC73879.1); Blastp hit to AAC73879.1 (368 aa), 95% identity in aa 1 - 368. (368 aa)
modFPutative ABC superfamily (atp_bind), molybdenum transporter; Similar to E. coli ATP-binding component of molybdate transport system (AAC73847.1); Blastp hit to AAC73847.1 (490 aa), 31% identity in aa 1 - 211. (491 aa)
tolASimilar to E. coli membrane spanning protein, required for outer membrane integrity (AAC73833.1); Blastp hit to AAC73833.1 (421 aa), 70% identity in aa 1 - 420. (407 aa)
tolRTol protein, role in outer membrane integrity; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (142 aa)
tolQTol protein, membrane-spanning inner membrane protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (230 aa)
STM0723Putative ABC-type polysaccharide/polyol phosphate transport system, ATPase component; Similar to E. coli ATP-binding component of putrescine transport system (AAC73942.1); Blastp hit to AAC73942.1 (404 aa), 28% identity in aa 61 - 259. (236 aa)
STM0707Putative outer membrane protein. (29 aa)
kdpAP-type ATPase, high-affinity potassium transport system, A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (559 aa)
kdpBP-type ATPase, high-affinity potassium transport system, B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (682 aa)
kdpCP-type ATPase, high-affinity potassium transport system, C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (194 aa)
lntApolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (512 aa)
ybeVPutative molecular chaperone, DnaJ family; Similar to E. coli orf, hypothetical protein (AAC73750.1); Blastp hit to AAC73750.1 (483 aa), 58% identity in aa 1 - 434. (490 aa)
ybeSPutative molecular chaperone, DnaJ family; Similar to E. coli putative enzyme of polynucleotide modification (AAC73747.1); Blastp hit to AAC73747.1 (475 aa), 45% identity in aa 1 - 474. (477 aa)
kdgT2Putative permease; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity); Belongs to the KdgT transporter family. (317 aa)
dacASimilar to E. coli D-alanyl-D-alanine carboxypeptidase, fraction A; penicillin-binding protein 5 (AAC73733.1); Blastp hit to AAC73733.1 (403 aa), 95% identity in aa 1 - 403; Belongs to the peptidase S11 family. (403 aa)
crcBHigh-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (127 aa)
fepASimilar to E. coli outer membrane receptor for ferric enterobactin (enterochelin) and colicins B and D (AAC73685.1); Blastp hit to AAC73685.1 (746 aa), 81% identity in aa 1 - 746. (751 aa)
STM0577Putative transport protein, PTS system; Similar to E. coli PTS enzyme IIAB, mannose-specific (AAC74887.1); Blastp hit to AAC74887.1 (323 aa), 26% identity in aa 5 - 126. (149 aa)
STM0576Putative transport protein, PTS system; Similar to E. coli PTS enzyme IIAB, mannose-specific (AAC74887.1); Blastp hit to AAC74887.1 (323 aa), 32% identity in aa 163 - 306. (156 aa)
STM0575Putative inner membrane protein; Similar to E. coli PTS enzyme IIC, mannose-specific (AAC74888.1); Blastp hit to AAC74888.1 (266 aa), 34% identity in aa 6 - 240. (247 aa)
STM0574Putative transport protein, PTS system; Similar to E. coli PTS enzyme IID, mannose-specific (AAC74889.1); Blastp hit to AAC74889.1 (286 aa), 37% identity in aa 4 - 284. (284 aa)
STM0562Putative transport protein; Similar to E. coli putative inner membrane component for iron transport (AAC73676.1); Blastp hit to AAC73676.1 (1047 aa), 82% identity in aa 981 - 1044. (59 aa)
sfbCPutative binding-protein-dependent transport systems inner membrane component; Similar to E. coli putative transport system permease protein (AAC73309.1); Blastp hit to AAC73309.1 (217 aa), 44% identity in aa 15 - 217. (219 aa)
sfbBPutative ABC-type transport system ATPase component/cell division protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (338 aa)
STM0509Putative outer membrane protein. (377 aa)
ybbMSimilar to E. coli putative metal resistance protein (AAC73593.1); Blastp hit to AAC73593.1 (268 aa), 88% identity in aa 10 - 267. (259 aa)
amtBPutative Amt family, ammonium transport protein; Similar to E. coli probable ammonium transporter (AAC73554.1); Blastp hit to AAC73554.1 (428 aa), 92% identity in aa 1 - 428. (428 aa)
cypDPeptidyl prolyl isomerase; Similar to E. coli putative protease maturation protein (AAC73544.1); Blastp hit to AAC73544.1 (623 aa), 88% identity in aa 1 - 623. (623 aa)
cyoCSimilar to E. coli cytochrome o ubiquinol oxidase subunit III (AAC73533.1); Blastp hit to AAC73533.1 (204 aa), 96% identity in aa 1 - 204. (204 aa)
cyoDSimilar to E. coli cytochrome o ubiquinol oxidase subunit IV (AAC73532.1); Blastp hit to AAC73532.1 (109 aa), 93% identity in aa 1 - 109. (109 aa)
yajRPutative MFS family transporter; Similar to E. coli putative transport protein (AAC73530.1); Blastp hit to AAC73530.1 (456 aa), 89% identity in aa 8 - 453. (449 aa)
phnT2-aminoethylphosphonate transporter ATPase component; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for energy coupling to the transport system. (369 aa)
phnU2-aminoethylphosphonate transporter, memrane component; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. (286 aa)
pgpAPhosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (171 aa)
tsxNucleoside channel; Functions as substrate-specific channel for nucleosides and deoxynucleosides. Functions also in albicidin uptake and as receptor for colicin K; Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family. (287 aa)
yajCPreprotein translocase IISP family, membrane subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (110 aa)
phoRSensory kinase in two-component regulatory system with PhoB, regulates pho regulon; Similar to E. coli positive and negative sensor protein for pho regulon (AAC73503.1); Blastp hit to AAC73503.1 (431 aa), 90% identity in aa 1 - 431. (431 aa)
STM0382Similar to E. coli putative transport protein (AAC74137.1); Blastp hit to AAC74137.1 (408 aa), 60% identity in aa 11 - 405. (403 aa)
sbmAPutative ABC superfamily transporter; Similar to E. coli sensitivity to microcin B17, possibly envelop protein (AAC73480.1); Blastp hit to AAC73480.1 (406 aa), 92% identity in aa 1 - 406. (406 aa)
STM0352Similar to E. coli acridine efflux pump (AAC73565.1); Blastp hit to AAC73565.1 (397 aa), 31% identity in aa 38 - 383; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (408 aa)
pagNHomolog of sapA; Haemagglutinin that facilitates the adhesion to and invasion of epithelial mammalian cells. Utilizes heparinated proteoglycan as a receptor to successfully invade host cells. (239 aa)
abcPutative ABC superfamily (atp_bind) transport system; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa)
yaeEPutative ABC superfamily (membrane) transport protein; Part of the binding-protein-dependent transport system for D- methionine and the toxic methionine analog alpha-methyl-methionine. Probably responsible for the translocation of the substrate across the membrane (By similarity). (217 aa)
yaeCPutative outer membrane lipoprotein; This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system. (271 aa)
fhuBHydroxamate-dependent iron uptake; Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity). Involved in ferrioxamine-mediated iron(III) utilization. (685 aa)
fhuCHydroxymate-dependent iron transport; ABC superfamily (atp_bind); similar to E. coli ATP-binding component of hydroxymate-dependent iron transport (AAC73262.1); Blastp hit to AAC73262.1 (265 aa), 92% identity in aa 1 - 265. (265 aa)
folK7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, PPPK; Similar to E. coli 7,8-dihydro-6-hydroxymethylpterin- pyrophosphokinase (AAC73253.1); Blastp hit to AAC73253.1 (159 aa), 87% identity in aa 1 - 148. (159 aa)
yadISimilar to E. coli putative PTS enzyme II B component (AAC73240.1); Blastp hit to AAC73240.1 (146 aa), 76% identity in aa 1 - 146. (146 aa)
gcdSimilar to E. coli glucose dehydrogenase (AAC73235.1); Blastp hit to AAC73235.1 (796 aa), 92% identity in aa 1 - 796. (796 aa)
kdgT2-keto-3-deoxygluconate permease; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity); Belongs to the KdgT transporter family. (317 aa)
aroPAPC family aromatic amino acid transporter; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. (457 aa)
ftsQCell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (276 aa)
ftsWEssential cell division gene; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (414 aa)
ftsLCell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (121 aa)
kefCCPA2 family K+ efflux antiporter, glutathione-regulated; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (620 aa)
yabFPutative NAD(P)H oxidoreductase; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily. (176 aa)
fixXPutative ferredoxin; Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster-containing protein (By similarity). (95 aa)
fixCRelated to carnitine metabolism protein; Could be part of an electron transfer system required for anaerobic carnitine reduction; Belongs to the ETF-QO/FixC family. (428 aa)
lspAProlipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (166 aa)
nhaANhaA family of transport protein, Na+/H antiporter, pH dependent; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (388 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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