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| | btuF | Putative cobalamin periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity). (266 aa) |
| | stfD | Periplasmic fimbrial chaperone StfD (gi|3747031). (250 aa) |
| | fhuD | Hydroxamate-dependent iron uptake; ABC superfamily (bind _prot); similar to E. coli hydroxamate-dependent iron uptake, cytoplasmic membrane component (AAC73263.1); Blastp hit to AAC73263.1 (296 aa), 82% identity in aa 1 - 296. (296 aa) |
| | stiB | Putative fimbrial chaparone; Similar to E. coli periplasmic chaperone, required for type 1 fimbriae (AAC77272.1); Blastp hit to AAC77272.1 (241 aa), 39% identity in aa 20 - 235. (227 aa) |
| | cueO | Putative multicopper oxidase; Probably involved in periplasmic detoxification of copper by oxidizing Cu(+) to Cu(2+) and thus preventing its uptake into the cytoplasm. Possesses phenoloxidase and ferroxidase activities and might be involved in the production of polyphenolic compounds and the prevention of oxidative damage in the periplasm (By similarity). (536 aa) |
| | yabN | Putative periplasmic binding protein of transport system; Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain. (552 aa) |
| | tbpA | Thiamine-binding periplasmic protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Is also involved in thiamine pyrophosphate transport. (327 aa) |
| | surA | Peptidyl-prolyl cis-trans isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (428 aa) |
| | STM0033 | Putative 5'-nucleotidase; Similar to E. coli UDP-sugar hydrolase (5'-nucleotidase) (AAC73582.1); Blastp hit to AAC73582.1 (550 aa), 26% identity in aa 1 - 253, 32% identity in aa 386 - 506; Belongs to the 5'-nucleotidase family. (523 aa) |
| | bcfH | Putative thiol-disulfide isomerase; Unknown (gi|6650097). (281 aa) |
| | bcfG | Fimbrial chaperone (gi|4959517). (243 aa) |
| | bcfB | Fimbrial chaperone (gi|4959512). (228 aa) |
| | safB | Putative fimbriae assembly chaparone; Similar to E. coli putative chaperone (AAC76177.1); Blastp hit to AAC76177.1 (231 aa), 35% identity in aa 26 - 223. (237 aa) |
| | sthA | Putative fimbrial chaparone protein; Similar to E. coli periplasmic chaperone, required for type 1 fimbriae (AAC77272.1); Blastp hit to AAC77272.1 (241 aa), 33% identity in aa 26 - 234. (227 aa) |
| | slt | Soluble lytic murein transglycosylase; Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division (By similarity). (657 aa) |
| | STM4575 | Putative outer membrane protein; Similar to E. coli putative transcriptional regulator (AAC76251.1); Blastp hit to AAC76251.1 (238 aa), 31% identity in aa 5 - 238. (229 aa) |
| | STM4574 | Putative outer membrane protein; Similar to E. coli putative transcriptional regulator (AAC76251.1); Blastp hit to AAC76251.1 (238 aa), 32% identity in aa 1 - 238. (229 aa) |
| | stjC | Putative fimbrial chaparone protein; Similar to E. coli putative chaperone (AAC76247.1); Blastp hit to AAC76247.1 (224 aa), 49% identity in aa 1 - 223. (235 aa) |
| | osmY | RpoS-dependent stationary phase gene; similar to E. coli hyperosmotically inducible periplasmic protein (AAC77329.1); Blastp hit to AAC77329.1 (201 aa), 89% identity in aa 1 - 201. (205 aa) |
| | mdoB | Phosphoglycerol transferase I; Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones; Belongs to the OpgB family. (750 aa) |
| | cpdB | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; This bifunctional enzyme catalyzes two consecutive reactions during ribonucleic acid degradation. Converts a 2',3'-cyclic nucleotide to a 3'-nucleotide and then the 3'-nucleotide to the corresponding nucleoside and phosphate; Belongs to the 5'-nucleotidase family. (647 aa) |
| | STM4351 | Similar to E. coli arginine 3rd transport system periplasmic binding protein (AAC73947.1); Blastp hit to AAC73947.1 (243 aa), 57% identity in aa 1 - 243; Belongs to the bacterial solute-binding protein 3 family. (246 aa) |
| | phoN | Nonspecific acid phosphatase precursor. (SW:PHON_SALTY). (250 aa) |
| | nrfC | Fe-S centers; similar to E. coli formate-dependent nitrite reductase; Fe-S centers (AAC77042.1); Blastp hit to AAC77042.1 (223 aa), 91% identity in aa 1 - 223. (223 aa) |
| | nrfB | Formate-dependent nitrite reductase; A penta-haeme cytochrome c; similar to E. coli formate-dependent nitrite reductase; a penta-haeme cytochrome c (AAC77041.1); Blastp hit to AAC77041.1 (190 aa), 88% identity in aa 1 - 190. (217 aa) |
| | nrfA | Nitrite reductase periplasmic cytochrome c(552); Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family. (478 aa) |
| | aphA | Non-specific acid phosphatase/phosphotransferase, class B; Dephosphorylates several organic phosphate monoesters such as 3'-UMP, 5'-UMP and pNPP. Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoesters to free hydroxyl groups of various organic compounds such as the 2'-, 3-, or 5'-hydroxyls of nucleosides and nucleotides. Also displays significant phosphomutase activity since it is able to catalyze the transfer of the phosphate group of 3'-AMP from the 3'-position both to the 2'- and 5'-positions. One of the physio [...] (237 aa) |
| | malM | Periplasmic protein of mal regulon; Not yet known. Might function in the uptake of a still unidentified substrate; To E.coli MalM. (305 aa) |
| | yjbH | Putative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC76999.1); Blastp hit to AAC76999.1 (698 aa), 92% identity in aa 1 - 698. (698 aa) |
| | yjbG | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76998.1); Blastp hit to AAC76998.1 (245 aa), 74% identity in aa 1 - 245. (245 aa) |
| | zraP | Zinc-resistance associated protein; Binds zinc. Could be an important component of the zinc- balancing mechanism (By similarity); Belongs to the ZraP family. (151 aa) |
| | STM4104 | Putative 5'-nucleotidase; Related esterase; similar to E. coli UDP-sugar hydrolase (5'-nucleotidase) (AAC73582.1); Blastp hit to AAC73582.1 (550 aa), 25% identity in aa 34 - 253, 28% identity in aa 383 - 506; 2',3'-cyclic phosphodiesterase; Belongs to the 5'-nucleotidase family. (518 aa) |
| | sbp | Sulfate transport protein; This protein specifically binds sulfate and is involved in its transmembrane transport; Belongs to the prokaryotic sulfate-binding protein family. (329 aa) |
| | cpxP | Periplasmic repressor of cpx regulon by interaction with CpxA; Rescue from transitory stresses; similar to E. coli orf, hypothetical protein (AAC76896.1); Blastp hit to AAC76896.1 (122 aa), 94% identity in aa 1 - 122. (166 aa) |
| | cpxA | Sensory kinase in two-component regulatory system with CpxR; Senses misfolded proteins in bacterial envelope; similar to E. coli probable sensor protein (histidine protein kinase), acting on arcA (AAC76893.1); Blastp hit to AAC76893.1 (457 aa), 96% identity in aa 1 - 457. (457 aa) |
| | dsbA | Periplasmic protein disulfide isomerase I; Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. It is required for pilus biogenesis (By similarity). Belongs to the thioredoxin family. DsbA subfamily. (207 aa) |
| | rbsB | D-ribose transport protein; Part of the ABC transporter complex RbsABC involved in ribose import. Binds ribose. (296 aa) |
| | STM3860 | Putative dipeptide/oligopeptide/nickel ABC-type transport systems; Periplasmic component; similar to E. coli putative transport protein (AAC73180.1); Blastp hit to AAC73180.1 (551 aa), 49% identity in aa 1 - 309, 29% identity in aa 297 - 548. (585 aa) |
| | pstS | High-affinity phosphate transporter; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (346 aa) |
| | torT | TMAO reductase system periplasmic protein TorT; Regulates tor operon; similar to E. coli part of regulation of tor operon, periplasmic (AAC74079.1); Blastp hit to AAC74079.1 (342 aa), 65% identity in aa 1 - 342. (346 aa) |
| | STM3820 | Similar to E. coli putative cytochrome C peroxidase (AAC76543.1); Blastp hit to AAC76543.1 (465 aa), 82% identity in aa 2 - 463. (466 aa) |
| | yidR | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76712.1); Blastp hit to AAC76712.1 (416 aa), 79% identity in aa 13 - 416. (408 aa) |
| | cigR | Putative inner membrane protein; Pathogenicity island encoded protein: SPI3; CigR (gi|4324614). (159 aa) |
| | yibP | Similar to E. coli putative membrane protein (AAC76637.1); Blastp hit to AAC76637.1 (427 aa), 91% identity in aa 1 - 427. (427 aa) |
| | malS | Alpha-amylase; Similar to E. coli alpha-amylase (AAC76595.1); Blastp hit to AAC76595.1 (676 aa), 81% identity in aa 1 - 676. (675 aa) |
| | bisC | Similar to E. coli biotin sulfoxide reductase (AAC76575.1); Blastp hit to AAC76575.1 (739 aa), 86% identity in aa 2 - 739; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (777 aa) |
| | lpfB | Long polar fimbrial chaperone; Required for the biogenesis of long polar fimbria; binds and interact with LpfA; Belongs to the periplasmic pilus chaperone family. (232 aa) |
| | dppA | Dipeptide transport protein; ABC superfamily (peri_perm); similar to E. coli dipeptide transport protein (AAC76569.1); Blastp hit to AAC76569.1 (535 aa), 93% identity in aa 1 - 535. (535 aa) |
| | yhjJ | Putative Zn-dependent peptidase; Protein YHJJ precursor. (SW:YHJJ_SALTY); Belongs to the peptidase M16 family. (495 aa) |
| | treF | Cytoplasmic trehalase; Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity. (549 aa) |
| | STM3598 | Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 46% identity in aa 22 - 348. (347 aa) |
| | STM3595 | Putative phosphatase. (423 aa) |
| | yhhM | Putative inner membrane protein; Similar to E. coli putative receptor (AAC76492.1); Blastp hit to AAC76492.1 (119 aa), 84% identity in aa 1 - 116. (123 aa) |
| | livJ | High-affinity branched-chain amino acid transporter; This protein is a component of the leucine, isoleucine, valine, threonine transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high-affinity transport of the branched-chain amino acids; Belongs to the leucine-binding protein family. (365 aa) |
| | livK | High-affinity branched-chain amino acid transporter; This protein is a component of the leucine-specific transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high-affinity transport of the branched-chain amino acids; Belongs to the leucine-binding protein family. (369 aa) |
| | ugpB | Sn-glycerol 3-phosphate transport protein; sn-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system UgpACE. (438 aa) |
| | ggt | Similar to E. coli gamma-glutamyltranspeptidase (AAC76472.1); Blastp hit to AAC76472.1 (580 aa), 91% identity in aa 2 - 580. (580 aa) |
| | envZ | Sensory histidine kinase in two-component regulatory system with OmpR; Member of the two-component regulatory system EnvZ/OmpR involved in osmoregulation (particularly of genes ompF and ompC) as well as other genes (By similarity). EnvZ functions as a membrane- associated protein kinase that phosphorylates OmpR in response to environmental signals; at low osmolarity OmpR activates ompF transcription, while at high osmolarity it represses ompF and activates ompC transcription (By similarity). (450 aa) |
| | ppiA | Peptidyl-prolyl cis-trans isomerase A; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). (190 aa) |
| | fkpA | Similar to E. coli FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) (AAC76372.1); Blastp hit to AAC76372.1 (270 aa), 90% identity in aa 1 - 270. (272 aa) |
| | msrP | Putative nitrate reductase; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal. The cata [...] (334 aa) |
| | degQ | Similar to E. coli serine endoprotease (AAC76266.1); Blastp hit to AAC76266.1 (455 aa), 89% identity in aa 1 - 455; Belongs to the peptidase S1C family. (455 aa) |
| | yhbN | Putative ABC superfamily transport protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (184 aa) |
| | yrbK | Putative inner membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. (191 aa) |
| | yrbC | Putative ABC superfamily transport protein; Atp&memb; similar to E. coli orf, hypothetical protein (AAC76224.1); Blastp hit to AAC76224.1 (211 aa), 93% identity in aa 1 - 211. (211 aa) |
| | dacB | Similar to E. coli D-alanyl-D-alanine carboxypeptidase, fraction B; penicillin-binding protein 4 (AAC76214.1); Blastp hit to AAC76214.1 (477 aa), 93% identity in aa 1 - 477. (477 aa) |
| | dsbL | Putative thiol-disulfide isomerase and thioredoxin; Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT. (223 aa) |
| | sufI | Suppressor of ftsI; Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress. (470 aa) |
| | hybA | Unknown; Intitally thought to be hydrogenase-2 small subunit which now identified as hybO; similar to E. coli hydrogenase-2 small subunit (AAC76032.1); Blastp hit to AAC76032.1 (328 aa), 95% identity in aa 1 - 328. (328 aa) |
| | STM3142 | Putative ferrichrome-binding periplasmic protein. (350 aa) |
| | STM3141 | Molybdenum-binding periplasmic protein. (236 aa) |
| | ansB | Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 92% identity in aa 1 - 348. (348 aa) |
| | endA | Similar to E. coli DNA-specific endonuclease I (AAC75982.1); Blastp hit to AAC75982.1 (235 aa), 87% identity in aa 1 - 235. (235 aa) |
| | dsbC | Protein disulfide isomerase II; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase. (237 aa) |
| | stdC | Putative fimbrial chaparone protein; Similar to E. coli putative chaperone (AAC73811.1); Blastp hit to AAC73811.1 (242 aa), 40% identity in aa 20 - 230. (247 aa) |
| | ptr | Protease III; Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin. (962 aa) |
| | amiC | Similar to E. coli putative amidase (AAC75856.1); Blastp hit to AAC75856.1 (447 aa), 94% identity in aa 31 - 446. (417 aa) |
| | mltA | Membrane-bound lytic murein transglycosylase A; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (365 aa) |
| | STM2950 | Putative metal-dependent hydrolases of the beta-lactamase superfamily II. (265 aa) |
| | iap | Similar to E. coli alkaline phosphatase isozyme conversion, aminopeptidase (AAC75795.1); Blastp hit to AAC75795.1 (345 aa), 85% identity in aa 1 - 344. (348 aa) |
| | prgK | Cell invasion protein; Required for invasion of epithelial cells. Could be involved in protein secretion; Belongs to the YscJ lipoprotein family. (252 aa) |
| | sitA | Fur regulated Salmonella iron transporter; SitA (gi|5231094); Belongs to the bacterial solute-binding protein 9 family. (305 aa) |
| | mltB | Similar to E. coli membrane-bound lytic murein transglycosylase B (AAC75743.1); Blastp hit to AAC75743.1 (361 aa), 92% identity in aa 1 - 361. (359 aa) |
| | emrA | Similar to E. coli multidrug resistance secretion protein (AAC75732.1); Blastp hit to AAC75732.1 (390 aa), 89% identity in aa 1 - 390. (390 aa) |
| | proX | Glycine/betaine/proline transport protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Binds glycine betaine and proline betaine with high affinity. (331 aa) |
| | STM2786 | Tricarboxylic transport protein. (325 aa) |
| | STM2759 | Putative dipeptide/oligopeptide/nickel ABC-type transport systems, periplasmic component; Similar to E. coli putative transport protein (AAC73180.1); Blastp hit to AAC73180.1 (551 aa), 27% identity in aa 19 - 545. (559 aa) |
| | rseB | Anti sigma E (sigma 24) factor, negative regulator; Similar to E. coli regulates activity of sigma-E factor (AAC75624.1); Blastp hit to AAC75624.1 (318 aa), 89% identity in aa 1 - 318. (318 aa) |
| | STM2610 | Gifsy-1 prophage protein; Similar to E. coli orf, hypothetical protein (AAC74262.1); Blastp hit to AAC74262.1 (133 aa), 80% identity in aa 1 - 133. (133 aa) |
| | yfhG | Putative transcriptional regulator of two-component regulator protein (EBP familiiy); EBP family; similar to E. coli putative alpha helix protein (AAC75608.1); Blastp hit to AAC75608.1 (237 aa), 63% identity in aa 1 - 234. (254 aa) |
| | bepA | Putative inner membrane or exported; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. (487 aa) |
| | amiA | N-acetylmuramoyl-l-alanine amidase I; Cell-wall hydrolase involved in septum cleavage during cell division; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. (289 aa) |
| | cysP | Thiosulfate transport protein; Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. This protein specifically binds thiosulfate and is involved in its transmembrane transport (By similarity). (338 aa) |
| | pgtC | Protein for signal transmission; Required for PgtP expression, it may act jointly with the PgtA/PgtB signaling proteins. (397 aa) |
| | mepA | Penicillin-insensitive murein DD-endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family. (274 aa) |
| | argT | Lysine/arginine/ornithine transport protein; Part of an ABC transporter involved in lysine, arginine and ornithine transport. Stimulates ATPase activity of HisP. (260 aa) |
| | hisJ | Histidine transport protein; Part of the histidine permease ABC transporter. Binds histidine. Interacts with HisQMP and stimulates ATPase activity of HisP, which results in histidine translocation. May have some additional function(s) in translocation that is independent of the stimulation of ATP hydrolysis. (260 aa) |
| | glpQ | Similar to E. coli glycerophosphodiester phosphodiesterase, periplasmic (AAC75299.1); Blastp hit to AAC75299.1 (358 aa), 89% identity in aa 1 - 357. (356 aa) |
| | rcsC | Sensory histidine kinase in two-component regulatory system with RcsB; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (948 aa) |
| | eco | Ecotin; General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases. (164 aa) |
| | napA | Periplasmic large subunit nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (828 aa) |
| | napB | Periplasmic small subunit nitrate reductase of cytochrome C550; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. (149 aa) |
| | yejA | Putative ABC transporter periplasmic binding protein; Similar to E. coli orf, hypothetical protein (AAC75238.1); Blastp hit to AAC75238.1 (606 aa), 86% identity in aa 3 - 603. (601 aa) |
| | mglB | Galactose transport protein; This protein is involved in the active transport of galactose and glucose. It plays a role in the chemotaxis towards the two sugars by interacting with the trg chemoreceptor. (332 aa) |
| | pbpG | D-alanyl-D-alanine endopeptidase; Penicillin-binding protein 7 and penicillin-binding protein 8; similar to E. coli penicillin-binding protein 7 (AAC75195.1); Blastp hit to AAC75195.1 (313 aa), 92% identity in aa 4 - 313; Belongs to the peptidase S11 family. (315 aa) |
| | bglX | Periplasmic beta-D-glucoside glucohydrolase; Periplasmic beta-glucosidase precursor. (SW:BGLX_SALTY); Belongs to the glycosyl hydrolase 3 family. (765 aa) |
| | yehZ | Putative ABC superfamily transport protein (bind_prot); Possibly glycine betaine choline transport for osmoprotection; similar to E. coli putative transport system permease protein (AAC75192.1); Blastp hit to AAC75192.1 (305 aa), 88% identity in aa 1 - 305. (305 aa) |
| | stcB | Similar to E. coli putative chaperone (AAC75171.1); Blastp hit to AAC75171.1 (239 aa), 64% identity in aa 16 - 239. (227 aa) |
| | STM2148 | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75168.1); Blastp hit to AAC75168.1 (172 aa), 80% identity in aa 63 - 172. (104 aa) |
| | dacD | DD-carboxypeptidase; Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Belongs to the peptidase S11 family. (390 aa) |
| | erfK | Putative periplasmic protein; Protein ERKF/SRFK precursor. (SW:ERFK_SALTY); Belongs to the YkuD family. (309 aa) |
| | fliY | Similar to E. coli putative periplasmic binding transport protein (AAC74987.1); Blastp hit to AAC74987.1 (266 aa), 92% identity in aa 1 - 266; Belongs to the bacterial solute-binding protein 3 family. (266 aa) |
| | znuA | ABC superfamily high affinity Zn transport protein; Binding protein; similar to E. coli putative adhesin (AAC74927.1); Blastp hit to AAC74927.1 (328 aa), 85% identity in aa 1 - 328. (333 aa) |
| | yobA | Similar Cu resistance protein CopC; Similar to E. coli orf, hypothetical protein (AAC74911.1); Blastp hit to AAC74911.1 (124 aa), 74% identity in aa 1 - 124. (124 aa) |
| | STM1849 | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74904.1); Blastp hit to AAC74904.1 (879 aa), 90% identity in aa 1 - 879. (879 aa) |
| | prc | Carboxy-terminal protease for penicillin-binding protein 3; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses (By similarity). (682 aa) |
| | treA | Trehalase, periplasmic; Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system; Belongs to the glycosyl hydrolase 37 family. (570 aa) |
| | oppA | Oligopeptide transport protein with chaperone properties; This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity; Belongs to the bacterial solute-binding protein 5 family. (582 aa) |
| | sapA | ABC superfamily peptide transport protein; Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides. Belongs to the bacterial solute-binding protein 5 family. (549 aa) |
| | pspE | Similar to E. coli phage shock protein (AAC74390.1); Blastp hit to AAC74390.1 (104 aa), 66% identity in aa 1 - 103. (104 aa) |
| | mppA | Periplasmic murein tripeptide transport protein; Also negative regulator of mulitple antibiotic resistance; similar to E. coli putative transport periplasmic protein (AAC74411.1); Blastp hit to AAC74411.1 (544 aa), 92% identity in aa 8 - 544. (537 aa) |
| | hslJ | Similar to E. coli heat shock protein hslJ (AAC74461.1); Blastp hit to AAC74461.1 (140 aa), 69% identity in aa 1 - 138. (136 aa) |
| | STM1633 | Similar to E. coli putative periplasmic binding transport protein (AAC74987.1); Blastp hit to AAC74987.1 (266 aa), 25% identity in aa 19 - 232. (253 aa) |
| | ydcG | Putative periplasmic glucans biosynthesis protein; Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs); Belongs to the OpgD/OpgG family. (551 aa) |
| | hdeB | Putative periplasmic transport protein; Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins. Belongs to the HdeB family. (109 aa) |
| | STM1540 | Putative hydrolase. (363 aa) |
| | STM1528 | Putative outer membrane protein. (180 aa) |
| | dcp | Dipeptidyl carboxypeptidase II; Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides. (680 aa) |
| | osmX | Putative periplasmic component; Part of the OsmU ABC transporter complex, which is involved in the uptake of osmoprotectants such as choline-O-sulfate and glycine betaine. (300 aa) |
| | asr | Acid shock protein; Required for growth and/or survival at acidic conditions. (94 aa) |
| | sodC-2 | Copper/zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (173 aa) |
| | ssaJ | Secretion system apparatus protein; Component of Salmonella pathogenicity island 2 (SPI-2) type III secretion system, required for secretion of some type III-secreted effectors including the SpvB toxin. (249 aa) |
| | ttrB | Tetrathionate reductase complex, subunit B; Part of a membrane-bound tetrathionate reductase that catalyzes the reduction of tetrathionate to thiosulfate. TtrB is probably involved in transfer of electrons from TtrC to TtrA. During mice infection, the ability to use tetrathionate as an electron acceptor is a growth advantage for S.typhimurium over the competing microbiota in the lumen of the inflamed gut. (250 aa) |
| | ynhG | Putative LysM domain protein; Similar to E. coli orf, hypothetical protein (AAC74748.1); Blastp hit to AAC74748.1 (334 aa), 85% identity in aa 1 - 334. (333 aa) |
| | spy | Similar to E. coli periplasmic protein related to spheroblast formation (AAC74813.1); Blastp hit to AAC74813.1 (161 aa), 89% identity in aa 1 - 161. (161 aa) |
| | STM1269 | Putative chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. (181 aa) |
| | STM1263 | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75039.1); Blastp hit to AAC75039.1 (216 aa), 71% identity in aa 3 - 216. (215 aa) |
| | STM1255 | Putative substrate-binding protein (gi|2337942). (544 aa) |
| | potD | Spermidine/putrescine transporter; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine. Polyamine binding protein; Belongs to the bacterial solute-binding protein PotD/PotF family. (348 aa) |
| | ycfU | Integral membrane protein ABC transporter; Similar to E. coli orf, hypothetical protein (AAC74200.1); Blastp hit to AAC74200.1 (399 aa), 93% identity in aa 1 - 399. (436 aa) |
| | ycfS | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74197.1); Blastp hit to AAC74197.1 (320 aa), 84% identity in aa 1 - 320. (321 aa) |
| | flgJ | Flagellar biosynthesis protein; Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; In the C-terminal section; belongs to the glycosyl hydrolase 73 family. (316 aa) |
| | flgI | Putative flagella basal body protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. (365 aa) |
| | flgA | Flagellar biosynthesis protein; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (219 aa) |
| | yceI | Putative secreted protein; Similar to E. coli orf, hypothetical protein (AAC74140.1); Blastp hit to AAC74140.1 (191 aa), 91% identity in aa 1 - 191. (191 aa) |
| | mdoG | Periplasmic glucans biosynthesis protein; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (511 aa) |
| | csgC | Putative curli production protein; Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE. Tafi are thought to be assembled via an extracellular nucleation- precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity); Belongs to the CsgC/AgfC family. (108 aa) |
| | nanM | Putative inner membrane protein; Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta- anomer, accelerating the equilibrium between the alpha- and beta- anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses; Belongs to the NanM family. (386 aa) |
| | agp | Glucose-1-phosphatase precursor. (SW:AGP_SALTY). (413 aa) |
| | scsC | Suppression of copper sensitivity protein; Suppressor for copper-sensitivity C (gi|2327005). (207 aa) |
| | STM1081 | Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC73646.1); Blastp hit to AAC73646.1 (183 aa), 59% identity in aa 1 - 180. (182 aa) |
| | ymbA | Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC74038.1); Blastp hit to AAC74038.1 (182 aa), 83% identity in aa 1 - 182. (187 aa) |
| | pqiB | Similar to E. coli paraquat-inducible protein B (AAC74037.1); Blastp hit to AAC74037.1 (546 aa), 89% identity in aa 1 - 546. (546 aa) |
| | sodC | Gifsy-2 prophage superoxide dismutase precursor (Cu-Zn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (177 aa) |
| | ycbK | Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC74012.1); Blastp hit to AAC74012.1 (182 aa), 95% identity in aa 1 - 182. (182 aa) |
| | lolA | Periplasmic protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (204 aa) |
| | STM0924 | Putative Fels-1 prophage Cu/Zn superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (174 aa) |
| | ybjP | Similar to E. coli putative enzyme (AAC73952.1); Blastp hit to AAC73952.1 (171 aa), 84% identity in aa 1 - 171. (171 aa) |
| | artI | Arginine transport system; ABC superfamily (bind_prot); similar to E. coli arginine 3rd transport system periplasmic binding protein (AAC73950.1); Blastp hit to AAC73950.1 (243 aa), 95% identity in aa 1 - 243; Belongs to the bacterial solute-binding protein 3 family. (243 aa) |
| | artJ | Arginine 3rd transport system; ABC superfamily (bind_prot); similar to E. coli arginine 3rd transport system periplasmic binding protein (AAC73947.1); Blastp hit to AAC73947.1 (243 aa), 91% identity in aa 1 - 243; Belongs to the bacterial solute-binding protein 3 family. (243 aa) |
| | potF | ABC superfamily (peri_perm), putrescine transporter; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family. (370 aa) |
| | dacC | Similar to E. coli D-alanyl-D-alanine carboxypeptidase; penicillin-binding protein 6 (AAC73926.1); Blastp hit to AAC73926.1 (400 aa), 92% identity in aa 1 - 400; Belongs to the peptidase S11 family. (400 aa) |
| | yliI | Similar to E. coli putative dehydrogenase (AAC73924.1); Blastp hit to AAC73924.1 (371 aa), 75% identity in aa 197 - 369. (226 aa) |
| | yliB | Putative ABC transporter periplasmic binding protein; Part of the ABC transporter complex GsiABCD involved in glutathione import. Binds glutathione. (512 aa) |
| | ybiK | Putative asparaginase; Degrades proteins damaged by L-isoaspartyl residue formation (also known as beta-Asp residues). Degrades L-isoaspartyl-containing di- and tripeptides. Acts best on iso-Asp-Leu, followed by iso-Asp-Ala, -His and to a lesser extent iso-Asp-Lys, -Phe and iso-Asp-Leu-Ala. Does not act on internal iso-Asp bonds (Als-iso-Asp-Leu-Ala). Does not act on alpha-Asp bonds. Has poor L-asparaginase activity. Belongs to the Ntn-hydrolase family. (313 aa) |
| | ybiS | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73906.1); Blastp hit to AAC73906.1 (306 aa), 92% identity in aa 1 - 306. (306 aa) |
| | glnH | Glutamine high-affinity transporter; ABC superfamily (bind_prot); similar to E. coli periplasmic glutamine-binding protein; permease (AAC73898.1); Blastp hit to AAC73898.1 (248 aa), 96% identity in aa 1 - 248; Belongs to the bacterial solute-binding protein 3 family. (248 aa) |
| | modA | Molybdate transporter; ABC superfamily (peri_perm); similar to E. coli molybdate-binding periplasmic protein; permease (AAC73850.1); Blastp hit to AAC73850.1 (257 aa), 86% identity in aa 1 - 257. (257 aa) |
| | ybgF | Putative periplasmic protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (262 aa) |
| | tolB | Tol protein required for outer membrane integrity; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. (430 aa) |
| | kdpD | Sensory kinase in two-component regulatory system wtih KdpE; Regulates kdp operon (high-affinity potassium transport system); similar to E. coli sensor for high-affinity potassium transport system (AAC73789.1); Blastp hit to AAC73789.1 (894 aa), 89% identity in aa 1 - 894. (894 aa) |
| | STM0691 | Putative periplasmic protein. (467 aa) |
| | lnt | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (512 aa) |
| | gltI | Glutamate/aspartate transporter; Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Binds to both glutamate and aspartate. (308 aa) |
| | dacA | Similar to E. coli D-alanyl-D-alanine carboxypeptidase, fraction A; penicillin-binding protein 5 (AAC73733.1); Blastp hit to AAC73733.1 (403 aa), 95% identity in aa 1 - 403; Belongs to the peptidase S11 family. (403 aa) |
| | rna | Similar to E. coli RNase I, cleaves phosphodiester bond between any two nucleotides (AAC73712.1); Blastp hit to AAC73712.1 (268 aa), 73% identity in aa 1 - 268; Belongs to the RNase T2 family. (268 aa) |
| | dsbG | Periplasmic disulfide isomerase, thiol-disulphide oxidase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (248 aa) |
| | fepB | ABC superfamily (peri_perm); similar to E. coli ferric enterobactin (enterochelin) binding protein; periplasmic component (AAC73693.1); Blastp hit to AAC73693.1 (318 aa), 79% identity in aa 1 - 318. (318 aa) |
| | fimC | Periplasmic chaperone, required for type 1 fimbriae; Required for the biogenesis of type 1 fimbriae. Binds and interact with FimH; Belongs to the periplasmic pilus chaperone family. (230 aa) |
| | tesA | Similar to E. coli acyl-CoA thioesterase I; also functions as protease I (AAC73596.1); Blastp hit to AAC73596.1 (208 aa), 89% identity in aa 2 - 205. (204 aa) |
| | ybaP | Putative cytoplasmic protein; Similar to E. coli putative ligase (AAC73584.1); Blastp hit to AAC73584.1 (264 aa), 66% identity in aa 1 - 264. (264 aa) |
| | ushA | UDP-sugar hydrolase 5'-nucleotidase; Silent protein USHA(0) precursor. (SW:USHA_SALTY); Belongs to the 5'-nucleotidase family. (550 aa) |
| | ybaE | Putative ABC transporter periplasmic binding protein; Similar to E. coli orf, hypothetical protein (AAC73548.1); Blastp hit to AAC73548.1 (566 aa), 79% identity in aa 1 - 565. (566 aa) |
| | phnS | 2-aminoethylphosphonate transporter, periplasmic-binding component; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import; Belongs to the bacterial solute-binding protein 1 family. (337 aa) |
| | STM0355 | Putative copper chaperone. (64 aa) |
| | stbB | Putative fimbriae; Similar to E. coli probable pilin chaperone similar to PapD (AAC73251.1); Blastp hit to AAC73251.1 (246 aa), 40% identity in aa 1 - 240. (253 aa) |
| | stbE | Putative fimbriae; Similar to E. coli periplasmic chaperone, required for type 1 fimbriae (AAC77272.1); Blastp hit to AAC77272.1 (241 aa), 30% identity in aa 32 - 241. (252 aa) |
| | STM0307 | Homology to Shigella VirG protein. (135 aa) |
| | gloB | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (251 aa) |
| | hlpA | Histone-like protein, located in outer membrane; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm. (161 aa) |
| | htrA | Periplasmic serine protease Do, heat shock protein; DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures. It degrades transiently denatured and unfolded proteins which accumulate in the periplasm following heat shock or other stress conditions. DegP is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for beta-branched side chain amino acids. Only unfolded proteins devoid of disulfide bonds appear capable of being cleaved, thereby preventing non-specific proteolysis of folded proteins. Its proteolyt [...] (475 aa) |
