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csgE csgE csgF csgF csgG csgG ompA ompA ompF ompF msbA msbA cydD cydD cydC cydC ybjZ ybjZ ybjY ybjY potI potI potH potH potG potG ybiU ybiU modF modF sdhB sdhB sdhA sdhA STM0723 STM0723 STM0707 STM0707 kdpA kdpA kdpB kdpB kdpC kdpC ybeC ybeC sfbC sfbC sfbB sfbB STM0509 STM0509 cyoC cyoC cyoD cyoD phnT phnT phnU phnU tsx tsx STM0352 STM0352 pagN pagN STM0290 STM0290 abc abc yaeE yaeE yaeC yaeC yaeT yaeT fhuB fhuB atpD atpD atpC atpC ugpB ugpB ugpA ugpA ugpE ugpE ugpC ugpC bigA bigA yheR yheR kefB kefB acrE acrE yhbG yhbG fhuC fhuC folK folK kefC kefC yabF yabF cysU cysU cysW cysW cysA cysA nuoA nuoA nuoB nuoB nuoC nuoC nuoE nuoE nuoF nuoF nuoG nuoG nuoH nuoH nuoI nuoI nuoJ nuoJ nuoK nuoK nuoL nuoL nuoM nuoM nuoN nuoN yehZ yehZ yehX yehX mdtA mdtA wza wza cbiM cbiM cbiN cbiN cboQ cboQ cbiO cbiO ompS ompS fliI fliI znuC znuC STM1741 STM1741 STM1653 STM1653 nifJ nifJ STM1530 STM1530 osmY-2 osmY-2 osmX osmX osmV osmV clcB clcB ompN ompN ssaN ssaN btuD btuD btuC btuC potA potA potB potB potC potC ycfW ycfW ycfV ycfV ycfU ycfU nlpB nlpB yjgQ yjgQ yjgP yjgP frdA frdA frdB frdB frdC frdC frdD frdD STM4259 STM4259 malK malK malE malE malF malF malG malG btuB btuB argH argH yneA yneA ego ego tatC tatC yqjC yqjC tolC tolC exbD exbD STM3142 STM3142 STM3075 STM3075 STM3074 STM3074 invC invC sitD sitD sitC sitC sitB sitB hycE hycE proX proX proW proW proV proV iroC iroC STM2690 STM2690 smpA smpA yfiO yfiO STM2599 STM2599 tatB tatB yfhL yfhL tatA tatA rbsA rbsA atpI atpI atpB atpB atpE atpE atpF atpF atpH atpH atpA atpA atpG atpG ndh ndh
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
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gene neighborhood
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csgECurli production assembly/transport component, 2nd curli operon; May be involved in the biogenesis of curli organelles. (131 aa)
csgFCurli production assembly/transport component, 2nd curli operon; May be involved in the biogenesis of curli organelles. (138 aa)
csgGPutative transcriptional regulator in curly assembly/transport, 2nd curli operon; May be involved in the biogenesis of curli organelles; Belongs to the CsgG family. (277 aa)
ompAPutative membrane component hydrogenase; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. (350 aa)
ompFOuter membrane protein 1a (ia;b;f), porin; Forms pores that allow passive diffusion of small molecules across the outer membrane. It is also a receptor for the bacteriophage T2 (By similarity). (363 aa)
msbAMulticopy repressor of htrB transport protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family. (582 aa)
cydDCytochrome-related transporter; Zn sensitive; ABC superfamily (atp&memb); similar to E. coli ATP-binding component of cytochrome-related transport, Zn sensitive (AAC73973.1); Blastp hit to AAC73973.1 (588 aa), 90% identity in aa 1 - 588. (588 aa)
cydCCytochrome-related transporter; ABC superfamily (atp&memb); similar to E. coli ATP-binding component of cytochrome-related transport (AAC73972.1); Blastp hit to AAC73972.1 (573 aa), 86% identity in aa 1 - 573. (573 aa)
ybjZPutative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (648 aa)
ybjYSimilar to E. coli putative membrane protein (AAC73965.1); Blastp hit to AAC73965.1 (380 aa), 83% identity in aa 12 - 378; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (372 aa)
potIPutrescine transporter; ABC superfamily (membrane); similar to E. coli putrescine transport protein; permease (AAC73944.1); Blastp hit to AAC73944.1 (281 aa), 94% identity in aa 1 - 281. (281 aa)
potHPutrescine transporter; ABC superfamily (membrane); similar to E. coli putrescine transport protein; permease (AAC73943.1); Blastp hit to AAC73943.1 (317 aa), 92% identity in aa 1 - 317. (317 aa)
potGPutrescine transporter; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (377 aa)
ybiUPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73908.1); Blastp hit to AAC73908.1 (421 aa), 85% identity in aa 1 - 421. (421 aa)
modFPutative ABC superfamily (atp_bind), molybdenum transporter; Similar to E. coli ATP-binding component of molybdate transport system (AAC73847.1); Blastp hit to AAC73847.1 (490 aa), 31% identity in aa 1 - 211. (491 aa)
sdhBSuccinate dehydrogenase, Fe-S protein; Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. (239 aa)
sdhASuccinate dehydrogenase, flavoprotein subunit; Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
STM0723Putative ABC-type polysaccharide/polyol phosphate transport system, ATPase component; Similar to E. coli ATP-binding component of putrescine transport system (AAC73942.1); Blastp hit to AAC73942.1 (404 aa), 28% identity in aa 61 - 259. (236 aa)
STM0707Putative outer membrane protein. (29 aa)
kdpAP-type ATPase, high-affinity potassium transport system, A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (559 aa)
kdpBP-type ATPase, high-affinity potassium transport system, B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (682 aa)
kdpCP-type ATPase, high-affinity potassium transport system, C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (194 aa)
ybeCPutative Sec-independent protein secretion pathway component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily. (67 aa)
sfbCPutative binding-protein-dependent transport systems inner membrane component; Similar to E. coli putative transport system permease protein (AAC73309.1); Blastp hit to AAC73309.1 (217 aa), 44% identity in aa 15 - 217. (219 aa)
sfbBPutative ABC-type transport system ATPase component/cell division protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (338 aa)
STM0509Putative outer membrane protein. (377 aa)
cyoCSimilar to E. coli cytochrome o ubiquinol oxidase subunit III (AAC73533.1); Blastp hit to AAC73533.1 (204 aa), 96% identity in aa 1 - 204. (204 aa)
cyoDSimilar to E. coli cytochrome o ubiquinol oxidase subunit IV (AAC73532.1); Blastp hit to AAC73532.1 (109 aa), 93% identity in aa 1 - 109. (109 aa)
phnT2-aminoethylphosphonate transporter ATPase component; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for energy coupling to the transport system. (369 aa)
phnU2-aminoethylphosphonate transporter, memrane component; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. (286 aa)
tsxNucleoside channel; Functions as substrate-specific channel for nucleosides and deoxynucleosides. Functions also in albicidin uptake and as receptor for colicin K; Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family. (287 aa)
STM0352Similar to E. coli acridine efflux pump (AAC73565.1); Blastp hit to AAC73565.1 (397 aa), 31% identity in aa 38 - 383; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (408 aa)
pagNHomolog of sapA; Haemagglutinin that facilitates the adhesion to and invasion of epithelial mammalian cells. Utilizes heparinated proteoglycan as a receptor to successfully invade host cells. (239 aa)
STM0290Putative cytoplasmic protein. (148 aa)
abcPutative ABC superfamily (atp_bind) transport system; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa)
yaeEPutative ABC superfamily (membrane) transport protein; Part of the binding-protein-dependent transport system for D- methionine and the toxic methionine analog alpha-methyl-methionine. Probably responsible for the translocation of the substrate across the membrane (By similarity). (217 aa)
yaeCPutative outer membrane lipoprotein; This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system. (271 aa)
yaeTPutative outer membrane antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. (804 aa)
fhuBHydroxamate-dependent iron uptake; Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity). Involved in ferrioxamine-mediated iron(III) utilization. (685 aa)
atpDMembrane-bound ATP synthase, F1 sector, beta-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (460 aa)
atpCMembrane-bound ATP synthase, F1 sector, epsilon-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (139 aa)
ugpBSn-glycerol 3-phosphate transport protein; sn-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system UgpACE. (438 aa)
ugpASn-glycerol 3-phosphate transport protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (295 aa)
ugpESn-glycerol 3-phosphate transport protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (281 aa)
ugpCSn-glycerol 3-phosphate transport protein; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system (Probable); Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (356 aa)
bigAPutative surface-exposed virulence protein BigA (gi|5081595). (1953 aa)
yheRPutative NAD(P)H oxidoreductase; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB. (183 aa)
kefBCPA2 family K+:H+ antiporter; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (601 aa)
acrESimilar to E. coli transmembrane protein affects septum formation and cell membrane permeability (AAC76297.1); Blastp hit to AAC76297.1 (385 aa), 88% identity in aa 1 - 380; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (385 aa)
yhbGPutative ABC superfamily transport protein; Atp_bind; similar to E. coli putative ATP-binding component of a transport system (AAC76233.1); Blastp hit to AAC76233.1 (241 aa), 98% identity in aa 1 - 241. (241 aa)
fhuCHydroxymate-dependent iron transport; ABC superfamily (atp_bind); similar to E. coli ATP-binding component of hydroxymate-dependent iron transport (AAC73262.1); Blastp hit to AAC73262.1 (265 aa), 92% identity in aa 1 - 265. (265 aa)
folK7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, PPPK; Similar to E. coli 7,8-dihydro-6-hydroxymethylpterin- pyrophosphokinase (AAC73253.1); Blastp hit to AAC73253.1 (159 aa), 87% identity in aa 1 - 148. (159 aa)
kefCCPA2 family K+ efflux antiporter, glutathione-regulated; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (620 aa)
yabFPutative NAD(P)H oxidoreductase; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily. (176 aa)
cysUThiosulfate transport protein; Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane (By similarity). (277 aa)
cysWThiosulfate permease W protein; ABC superfamily (membrane); similar to E. coli sulfate transport system permease W protein (AAC75476.1); Blastp hit to AAC75476.1 (149 aa), 99% identity in aa 1 - 149. (291 aa)
cysASulfate permease A protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (365 aa)
nuoANADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (147 aa)
nuoBNADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (220 aa)
nuoCNADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. (600 aa)
nuoENADH dehydrogenase I chain E; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 24 kDa subunit family. (166 aa)
nuoFNADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity). (445 aa)
nuoGNADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity). (910 aa)
nuoHNADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (325 aa)
nuoINADH dehydrogenase I chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa)
nuoJNADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa)
nuoKNADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa)
nuoLSimilar to E. coli NADH dehydrogenase I chain L (AAC75338.1); Blastp hit to AAC75338.1 (613 aa), 94% identity in aa 1 - 613. (613 aa)
nuoMSimilar to E. coli NADH dehydrogenase I chain M (AAC75337.1); Blastp hit to AAC75337.1 (509 aa), 96% identity in aa 1 - 509. (509 aa)
nuoNNADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (425 aa)
yehZPutative ABC superfamily transport protein (bind_prot); Possibly glycine betaine choline transport for osmoprotection; similar to E. coli putative transport system permease protein (AAC75192.1); Blastp hit to AAC75192.1 (305 aa), 88% identity in aa 1 - 305. (305 aa)
yehXPutative ABC-type proline/glycine betaine transport system, ATPase component; Similar to E. coli putative ATP-binding component of a transport system (AAC75190.1); Blastp hit to AAC75190.1 (308 aa), 87% identity in aa 1 - 307. (315 aa)
mdtAPutative HlyD family secretion protein; Similar to E. coli putative membrane protein (AAC75135.1); Blastp hit to AAC75135.1 (464 aa), 82% identity in aa 50 - 464; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (413 aa)
wzaPutative polysaccharide export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. (379 aa)
cbiMSynthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. (245 aa)
cbiNSynthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity; Belongs to the CbiN family. (93 aa)
cboQSynthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity; Belongs to the CbiQ family. (225 aa)
cbiOSynthesis of vitamin B12 adenosyl cobalamide precursor; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family. (271 aa)
ompSSimilar to E. coli putative outer membrane protein (AAC74459.1); Blastp hit to AAC74459.1 (377 aa), 71% identity in aa 1 - 236, 60% identity in aa 174 - 377; Belongs to the Gram-negative porin family. (398 aa)
fliIFlagellum-specific ATP synthase; Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage; Belongs to the ATPase alpha/beta chains family. (456 aa)
znuCABC superfamily high affinity Zn transport protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system (Probable). Seems to be important for the virulence. (268 aa)
STM1741Putative voltage-gated potassium channel. (278 aa)
STM1653Putative membrane transporter of cations; Similar to E. coli methylviologen resistance (AAC73644.1); Blastp hit to AAC73644.1 (110 aa), 59% identity in aa 5 - 110. (112 aa)
nifJSimilar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174. (1174 aa)
STM1530Similar to E. coli putative outer membrane protein (AAC74459.1); Blastp hit to AAC74459.1 (377 aa), 61% identity in aa 2 - 377; Belongs to the Gram-negative porin family. (372 aa)
osmY-2ABC-type transport system protein; Part of the OsmU ABC transporter complex, which is involved in the uptake of osmoprotectants such as choline-O-sulfate and glycine betaine. Probably responsible for the translocation of the substrate across the membrane. (236 aa)
osmXPutative periplasmic component; Part of the OsmU ABC transporter complex, which is involved in the uptake of osmoprotectants such as choline-O-sulfate and glycine betaine. (300 aa)
osmVABC-type proline/glycine betaine transport system; Part of the OsmU ABC transporter complex, which is involved in the uptake of osmoprotectants such as choline-O-sulfate and glycine betaine. Probably responsible for energy coupling to the transport system. (382 aa)
clcBPutative chloride channel protein; Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response; Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily. (429 aa)
ompNOuter membrane protein N; Non-specific porin; similar to E. coli putative outer membrane protein (AAC74459.1); Blastp hit to AAC74459.1 (377 aa), 81% identity in aa 1 - 377. (377 aa)
ssaNHomology with the YscN family of proteins; probable secretion system apparatus ATP synthase SSAN. (SW:SSAN_SALTY); Belongs to the ATPase alpha/beta chains family. (433 aa)
btuDVitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (249 aa)
btuCVitamin B12 transport protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. (326 aa)
potASpermidine/putrescine transporter; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa)
potBSpermidine/putrescine transporter; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (287 aa)
potCSpermidine/putrescine transporter; ABC superfamily (membrane); similar to E. coli spermidine/putrescine transport system permease (AAC74208.1); Blastp hit to AAC74208.1 (264 aa), 96% identity in aa 1 - 258. (259 aa)
ycfWIntegral membrane protein ABC transporter; Similar to E. coli putative kinase (AAC74202.1); Blastp hit to AAC74202.1 (414 aa), 92% identity in aa 1 - 414. (414 aa)
ycfVATP-binding protein ABC transporter; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (233 aa)
ycfUIntegral membrane protein ABC transporter; Similar to E. coli orf, hypothetical protein (AAC74200.1); Blastp hit to AAC74200.1 (399 aa), 93% identity in aa 1 - 399. (436 aa)
nlpBLipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (344 aa)
yjgQPutative permease; Similar to E. coli orf, hypothetical protein (AAC77219.1); Blastp hit to AAC77219.1 (361 aa), 97% identity in aa 2 - 361. (360 aa)
yjgPPutative permease; Similar to E. coli orf, hypothetical protein (AAC77218.1); Blastp hit to AAC77218.1 (366 aa), 94% identity in aa 1 - 366. (366 aa)
frdAFumarate reductase; Anaerobic; flavoprotein subunit; similar to E. coli fumarate reductase, anaerobic, flavoprotein subunit (AAC77114.1); Blastp hit to AAC77114.1 (602 aa), 95% identity in aa 1 - 595. (596 aa)
frdBFumarate reductase; Anaerobic; Fe-S protein subunit; similar to E. coli fumarate reductase, anaerobic, iron-sulfur protein subunit (AAC77113.1); Blastp hit to AAC77113.1 (244 aa), 95% identity in aa 1 - 244; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (244 aa)
frdCFumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa)
frdDFumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (119 aa)
STM4259ABC exporter outer membrane component homolog (gi|7467234). (439 aa)
malKMaltose transport protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (369 aa)
malEMaltose transport protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. (399 aa)
malFMaltose transport protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. (514 aa)
malGMaltose transport protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. (296 aa)
btuBOuter membrane receptor for transport of vitamin B12, E colicins, and bacteriophage BF23; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (614 aa)
argHSimilar to E. coli argininosuccinate lyase (AAC76942.1); Blastp hit to AAC76942.1 (457 aa), 94% identity in aa 1 - 456. (458 aa)
yneAPutative sugar transport protein; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (Probable); Belongs to the bacterial solute-binding protein 2 family. (340 aa)
egoPutative ABC-type sugar aldose transport system; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system (Probable). (511 aa)
tatCComponent of sec-independent protein export; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (259 aa)
yqjCPutative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76132.1); Blastp hit to AAC76132.1 (127 aa), 84% identity in aa 6 - 127. (122 aa)
tolCOuter membrane channel; Specific tolerance to colicin E1; segregation of daughter chromosomes; role in organic solvent tolerance; similar to E. coli outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (AAC76071.1); Blastp hit to AAC76071.1 (495 aa), 89% identity in aa 1 - 495. (491 aa)
exbDtonB-dependent uptake of B colicins; similar to E. coli uptake of enterochelin; tonB-dependent uptake of B colicins (AAC76041.1); Blastp hit to AAC76041.1 (141 aa), 93% identity in aa 1 - 141. (141 aa)
STM3142Putative ferrichrome-binding periplasmic protein. (350 aa)
STM3075Putative ABC-type cobalt transport system; ATPase component; similar to E. coli ATP-binding component of sulfate permease A protein; chromate resistance (AAC75475.1); Blastp hit to AAC75475.1 (365 aa), 33% identity in aa 18 - 219. (218 aa)
STM3074Putative ABC-type cobalt transport system; ATPase component; similar to E. coli ATP-binding component of putrescine transport system (AAC73942.1); Blastp hit to AAC73942.1 (404 aa), 38% identity in aa 74 - 207. (225 aa)
invCSurface presentation of antigens; Necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase. May energize the protein export apparatus encoded in the inv locus which is required for the surface presentation of determinants needed for the entry of salmonella species into mammalian cells. (431 aa)
sitDFur regulated Salmonella iron transporter; SitD (gi|5231097). (282 aa)
sitCFur regulated Salmonella iron transporter; SitC (gi|5231096). (286 aa)
sitBFur regulated Salmonella iron transporter; SitB (gi|5231095). (273 aa)
hycEPart of FHL complex; similar to E. coli large subunit of hydrogenase 3 (part of FHL complex) (AAC75763.1); Blastp hit to AAC75763.1 (569 aa), 97% identity in aa 1 - 569. (569 aa)
proXGlycine/betaine/proline transport protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Binds glycine betaine and proline betaine with high affinity. (331 aa)
proWGlycine/betaine/proline transport protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (354 aa)
proVGlycine/betaine/proline transport protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for energy coupling to the transport system. (400 aa)
iroCPutative ATP binding cassette (ABC) transporter; Similar to E. coli ATP-binding transport protein; multicopy suppressor of htrB (AAC74000.1); Blastp hit to AAC74000.1 (582 aa), 26% identity in aa 14 - 582, 29% identity in aa 34 - 565. (1217 aa)
STM2690Putative outer membrane efflux protein; Similar to E. coli putative resistance protein (AAC73673.1); Blastp hit to AAC73673.1 (457 aa), 24% identity in aa 67 - 450. (469 aa)
smpASmall membrane protein A; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (112 aa)
yfiOPutative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery. (245 aa)
STM2599Gifsy-1 prophage protein; Similar to E. coli putative virulence protein (AAC74514.1); Blastp hit to AAC74514.1 (402 aa), 36% identity in aa 1 - 384. (416 aa)
tatBComponent of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (182 aa)
yfhLPutative ferredoxin; Similar to E. coli orf, hypothetical protein (AAC75615.1); Blastp hit to AAC75615.1 (86 aa), 94% identity in aa 1 - 86. (86 aa)
tatAComponent of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (84 aa)
rbsAD-ribose high-affinity transport protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (501 aa)
atpISimilar to E. coli membrane-bound ATP synthase, dispensable protein, affects expression of atpB (AAC76762.1); Blastp hit to AAC76762.1 (130 aa), 91% identity in aa 5 - 130. (126 aa)
atpBMembrane-bound ATP synthase, F0 sector, subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (271 aa)
atpEMembrane-bound ATP synthase, F0 sector, subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (79 aa)
atpFMembrane-bound ATP synthase, F0 sector, subunit b; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (156 aa)
atpHMembrane-bound ATP synthase, F1 sector, delta-subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (177 aa)
atpAMembrane-bound ATP synthase, F1 sector, alpha-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (513 aa)
atpGMembrane-bound ATP synthase, F1 sector, gamma-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (287 aa)
ndhSimilar to E. coli respiratory NADH dehydrogenase (AAC74193.1); Blastp hit to AAC74193.1 (434 aa), 97% identity in aa 1 - 434; cupric reductase. (434 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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