STRINGSTRING
STM4417 STM4417 STM4539 STM4539 STM4540 STM4540 yraO yraO gutQ gutQ STM2756 STM2756 yfhH yfhH STM3601 STM3601 glmS glmS yrbH yrbH STM0573 STM0573 STM0572 STM0572 ghmA ghmA murQ murQ yebK yebK STM1127 STM1127
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STM4417Putative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC75614.1); Blastp hit to AAC75614.1 (306 aa), 25% identity in aa 31 - 278. (277 aa)
STM4539Putative glucosamine-fructose-6-phosphate aminotransferase; Similar to E. coli L-glutamine:D-fructose-6-phosphate aminotransferase (AAC76752.1); Blastp hit to AAC76752.1 (609 aa), 24% identity in aa 262 - 596. (353 aa)
STM4540Putative glucosamine-fructose-6-phosphate aminotransferase; Similar to E. coli putative transport protein (AAC76396.1); Blastp hit to AAC76396.1 (347 aa), 26% identity in aa 42 - 341. (343 aa)
yraOPutative phosphoheptose isomerase; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. (196 aa)
gutQPutative polysialic acid capsule expression protein; Catalyzes the reversible aldol-ketol isomerization between D- ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P). It is also able of sustaining the biosynthetic pathway of 3-deoxy-D-manno- octulosonate (KDO), a unique 8-carbon sugar component of lipopolysaccharides (LPSs) (By similarity). (308 aa)
STM2756Putative sugar phosphate aminotransferase; Similar to E. coli orf, hypothetical protein (AAC75480.1); Blastp hit to AAC75480.1 (285 aa), 32% identity in aa 113 - 227. (187 aa)
yfhHPutative ABC superfamily transport protein; Membrane; similar to E. coli orf, hypothetical protein (AAC75614.1); Blastp hit to AAC75614.1 (306 aa), 83% identity in aa 25 - 306. (282 aa)
STM3601Putative phosphosugar isomerase; Similar to E. coli putative transport protein (AAC76396.1); Blastp hit to AAC76396.1 (347 aa), 28% identity in aa 42 - 303. (325 aa)
glmSL-glutamine:D-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
yrbHPutative polysialic acid capsule expression protein; Involved in the biosynthesis of 3-deoxy-D-manno-octulosonate (KDO), a unique 8-carbon sugar component of lipopolysaccharides (LPSs). Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P) (By similarity). (328 aa)
STM0573Putative inner membrane protein; Similar to E. coli L-glutamine:D-fructose-6-phosphate aminotransferase (AAC76752.1); Blastp hit to AAC76752.1 (609 aa), 21% identity in aa 293 - 601. (347 aa)
STM0572Putative phosphosugar isomerases; Similar to E. coli putative transport protein (AAC76396.1); Blastp hit to AAC76396.1 (347 aa), 27% identity in aa 42 - 299. (328 aa)
ghmAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (192 aa)
murQPutative aminotransferase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. (297 aa)
yebKPutative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC74923.1); Blastp hit to AAC74923.1 (289 aa), 92% identity in aa 1 - 289. (289 aa)
STM1127Putative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC75480.1); Blastp hit to AAC75480.1 (285 aa), 29% identity in aa 15 - 264. (293 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.