STRINGSTRING
STM2912 STM2912 gcvA gcvA lysR lysR STM3020 STM3020 nhaR nhaR leuO leuO yafC yafC sinR sinR STM0333 STM0333 ybbS ybbS ybdO ybdO ybeF ybeF STM0692 STM0692 STM0763 STM0763 STM0764 STM0764 STM0859 STM0859 STM0952 STM0952 ydhB ydhB ynfL ynfL yneJ yneJ ydcI ydcI STM1677 STM1677 cysB cysB yeeY yeeY STM2180 STM2180 yeiE yeiE STM2281 STM2281 lrhA lrhA xapR xapR yfeR yfeR STM2575 STM2575 yfiE yfiE iciA iciA STM3121 STM3121 yhaJ yhaJ tdcA tdcA yhcS yhcS yhjC yhjC STM3736 STM3736 dsdC dsdC STM3834 STM3834 yidZ yidZ yifA yifA ilvY ilvY metR metR oxyR oxyR STM4270 STM4270 yjiE yjiE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STM2912Similar to E. coli putative transcriptional regulator LYSR-type (AAC73313.1); Blastp hit to AAC73313.1 (304 aa), 32% identity in aa 6 - 289; Belongs to the LysR transcriptional regulatory family. (310 aa)
gcvARegulator of gcv operon; LysR family; similar to E. coli positive regulator of gcv operon (AAC75850.1); Blastp hit to AAC75850.1 (305 aa), 98% identity in aa 1 - 305; Belongs to the LysR transcriptional regulatory family. (305 aa)
lysRPositive LysR family transcriptional regulator; Similar to E. coli positive regulator for lys (AAC75878.1); Blastp hit to AAC75878.1 (311 aa), 86% identity in aa 1 - 311; Belongs to the LysR transcriptional regulatory family. (311 aa)
STM3020Similar to E. coli putative transcriptional regulator LYSR-type (AAC73606.1); Blastp hit to AAC73606.1 (308 aa), 26% identity in aa 2 - 275; Belongs to the LysR transcriptional regulatory family. (287 aa)
nhaRLysR family; similar to E. coli transcriptional activator of nhaA (AAC73131.1); Blastp hit to AAC73131.1 (301 aa), 92% identity in aa 1 - 296; Belongs to the LysR transcriptional regulatory family. (299 aa)
leuOPutative LysR family transcriptional regulator; Probable activator protein in leuabcd operon. (SW:LEUO_SALTY); Belongs to the LysR transcriptional regulatory family. (314 aa)
yafCSimilar to E. coli putative transcriptional regulator LYSR-type (AAC73313.1); Blastp hit to AAC73313.1 (304 aa), 90% identity in aa 1 - 303; Belongs to the LysR transcriptional regulatory family. (304 aa)
sinRTranscriptional regulator; Probable regulatory protein. Its target is not known. (315 aa)
STM0333Similar to E. coli putative transcriptional regulator LYSR-type (AAC74869.1); Blastp hit to AAC74869.1 (314 aa), 44% identity in aa 2 - 307; Belongs to the LysR transcriptional regulatory family. (321 aa)
ybbSPutative LysR family transcriptional regulator; Positive regulator essential for the expression of allD operon. Binds to the allD promoter (By similarity). (308 aa)
ybdOSimilar to E. coli putative transcriptional regulator LYSR-type (AAC73704.1); Blastp hit to AAC73704.1 (300 aa), 54% identity in aa 1 - 298; Belongs to the LysR transcriptional regulatory family. (300 aa)
ybeFSimilar to E. coli putative transcriptional regulator LYSR-type (AAC73730.1); Blastp hit to AAC73730.1 (266 aa), 68% identity in aa 1 - 266; Belongs to the LysR transcriptional regulatory family. (317 aa)
STM0692Putative LysR family transcriptional regulator; Similar to E. coli nitrogen assimilation control protein (AAC75050.1); Blastp hit to AAC75050.1 (305 aa), 32% identity in aa 1 - 301; Belongs to the LysR transcriptional regulatory family. (308 aa)
STM0763Transcriptional regulator, lysR family; Similar to E. coli cyn operon positive regulator (AAC73441.1); Blastp hit to AAC73441.1 (299 aa), 25% identity in aa 16 - 288; Belongs to the LysR transcriptional regulatory family. (283 aa)
STM0764Similar to E. coli putative transcriptional regulator LYSR-type (AAC77283.1); Blastp hit to AAC77283.1 (303 aa), 30% identity in aa 9 - 300; Belongs to the LysR transcriptional regulatory family. (327 aa)
STM0859Similar to E. coli putative transcriptional regulator LYSR-type (AAC74667.1); Blastp hit to AAC74667.1 (297 aa), 28% identity in aa 1 - 264; Belongs to the LysR transcriptional regulatory family. (296 aa)
STM0952Similar to E. coli putative transcriptional regulator LYSR-type (AAC73313.1); Blastp hit to AAC73313.1 (304 aa), 31% identity in aa 1 - 291; Belongs to the LysR transcriptional regulatory family. (303 aa)
ydhBSimilar to E. coli putative transcriptional regulator LYSR-type (AAC74731.1); Blastp hit to AAC74731.1 (310 aa), 90% identity in aa 1 - 310; Belongs to the LysR transcriptional regulatory family. (310 aa)
ynfLSimilar to E. coli putative transcriptional regulator LYSR-type (AAC74667.1); Blastp hit to AAC74667.1 (297 aa), 83% identity in aa 1 - 297; Belongs to the LysR transcriptional regulatory family. (299 aa)
yneJSimilar to E. coli putative transcriptional regulator LYSR-type (AAC74599.1); Blastp hit to AAC74599.1 (293 aa), 84% identity in aa 1 - 283; Belongs to the LysR transcriptional regulatory family. (290 aa)
ydcISimilar to E. coli putative transcriptional regulator LYSR-type (AAC74504.1); Blastp hit to AAC74504.1 (354 aa), 83% identity in aa 48 - 353; Belongs to the LysR transcriptional regulatory family. (307 aa)
STM1677Similar to E. coli putative transcriptional regulator LYSR-type (AAC76546.1); Blastp hit to AAC76546.1 (323 aa), 35% identity in aa 25 - 313; Belongs to the LysR transcriptional regulatory family. (301 aa)
cysBTranscriptional regulator for cysteine regulon; This protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of L-cysteine from inorganic sulfate. The inducer for CysB is N-acetylserine. CysB inhibits its own transcription. (324 aa)
yeeYSimilar to E. coli putative transcriptional regulator LYSR-type (AAC75076.1); Blastp hit to AAC75076.1 (316 aa), 87% identity in aa 8 - 309; Belongs to the LysR transcriptional regulatory family. (304 aa)
STM2180Similar to E. coli putative transcriptional regulator LYSR-type (AAC74504.1); Blastp hit to AAC74504.1 (354 aa), 28% identity in aa 54 - 336; Belongs to the LysR transcriptional regulatory family. (302 aa)
yeiESimilar to E. coli putative transcriptional regulator LYSR-type (AAC75218.1); Blastp hit to AAC75218.1 (293 aa), 91% identity in aa 1 - 287; Belongs to the LysR transcriptional regulatory family. (287 aa)
STM2281Putative LysR family transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC75298.1); Blastp hit to AAC75298.1 (68 aa), 80% identity in aa 1 - 66; Belongs to the LysR transcriptional regulatory family. (292 aa)
lrhASimilar to E. coli NADH dehydrogenase transcriptional regulator, LysR family (AAC75349.1); Blastp hit to AAC75349.1 (312 aa), 86% identity in aa 1 - 312; Belongs to the LysR transcriptional regulatory family. (312 aa)
xapRRegulator for XapA; LysR family; similar to E. coli regulator for xapA (AAC75458.1); Blastp hit to AAC75458.1 (294 aa), 80% identity in aa 1 - 293; Belongs to the LysR transcriptional regulatory family. (294 aa)
yfeRSimilar to E. coli putative transcriptional regulator LYSR-type (AAC75462.1); Blastp hit to AAC75462.1 (308 aa), 79% identity in aa 1 - 308; Belongs to the LysR transcriptional regulatory family. (308 aa)
STM2575Putative LysR family transcriptional regulator; Similar to E. coli cyn operon positive regulator (AAC73441.1); Blastp hit to AAC73441.1 (299 aa), 30% identity in aa 4 - 229; Belongs to the LysR transcriptional regulatory family. (308 aa)
yfiESimilar to E. coli putative transcriptional regulator LYSR-type (AAC75630.1); Blastp hit to AAC75630.1 (308 aa), 78% identity in aa 16 - 305; Belongs to the LysR transcriptional regulatory family. (299 aa)
iciAInhibitor of replication initiation; Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. (297 aa)
STM3121Putative transcriptional regulator (gi|5852589); Belongs to the LysR transcriptional regulatory family. (292 aa)
yhaJSimilar to E. coli putative transcriptional regulator LYSR-type (AAC76140.1); Blastp hit to AAC76140.1 (298 aa), 96% identity in aa 1 - 298; Belongs to the LysR transcriptional regulatory family. (298 aa)
tdcALysR family; similar to E. coli transcriptional activator of tdc operon (AAC76153.1); Blastp hit to AAC76153.1 (312 aa), 89% identity in aa 1 - 311; Belongs to the LysR transcriptional regulatory family. (312 aa)
yhcSSimilar to E. coli putative transcriptional regulator LYSR-type (AAC76275.1); Blastp hit to AAC76275.1 (309 aa), 95% identity in aa 1 - 309; Belongs to the LysR transcriptional regulatory family. (309 aa)
yhjCSimilar to E. coli putative transcriptional regulator LYSR-type (AAC76546.1); Blastp hit to AAC76546.1 (323 aa), 66% identity in aa 25 - 320; Belongs to the LysR transcriptional regulatory family. (299 aa)
STM3736Similar to E. coli putative transcriptional regulator LYSR-type (AAC73730.1); Blastp hit to AAC73730.1 (266 aa), 25% identity in aa 2 - 219; Belongs to the LysR transcriptional regulatory family. (300 aa)
dsdCLysR family transcriptional activator; Similar to E. coli D-serine dehydratase (deaminase) transcriptional activator (AAC75423.1); Blastp hit to AAC75423.1 (311 aa), 90% identity in aa 1 - 307; Belongs to the LysR transcriptional regulatory family. (307 aa)
STM3834Similar to E. coli putative transcriptional regulator LYSR-type (AAC73855.1); Blastp hit to AAC73855.1 (338 aa), 27% identity in aa 22 - 318; Belongs to the LysR transcriptional regulatory family. (298 aa)
yidZPutative LysR family transcriptional regulator; Involved in anaerobic NO protection. (319 aa)
yifAPutative LysR family transcriptional regulator; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon. (282 aa)
ilvYPositive LysR family regulator for ilvC; This protein activates the transcription of the IlvC gene in the presence of acetolactate or acetohydroxybutyrate. IlvY is also a negative regulator of its own expression; Belongs to the LysR transcriptional regulatory family. (295 aa)
metRRegulator for metE and metH; Control of the last step in methionine biosynthesis; MetR is a positive activator of the metA, metE and metH genes. It is also a negative regulator of its own expression; Belongs to the LysR transcriptional regulatory family. (317 aa)
oxyRRegulatory protein sensor for oxidative stress; Regulates intracellular hydrogen peroxide (LysR family); similar to E. coli activator, hydrogen peroxide-inducible genes (AAC76943.1); Blastp hit to AAC76943.1 (305 aa), 95% identity in aa 1 - 305; Belongs to the LysR transcriptional regulatory family. (305 aa)
STM4270Putative LysR family transcriptional regulator; Similar to E. coli activator, hydrogen peroxide-inducible genes (AAC76943.1); Blastp hit to AAC76943.1 (305 aa), 28% identity in aa 1 - 275; Belongs to the LysR transcriptional regulatory family. (295 aa)
yjiESimilar to E. coli putative transcriptional regulator LYSR-type (AAC77283.1); Blastp hit to AAC77283.1 (303 aa), 81% identity in aa 1 - 302; Belongs to the LysR transcriptional regulatory family. (302 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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