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lrp lrp asnC asnC yiiL yiiL yneC yneC STM3461 STM3461 ygiN ygiN STM2446 STM2446 yciI yciI STM1001 STM1001 ybaO ybaO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lrpRegulator for lrp regulon and high-affinity branched-chain amino acid transport system; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes. (164 aa)
asnCAsnC family; similar to E. coli regulator for asnA, asnC and gidA (AAC76766.1); Blastp hit to AAC76766.1 (152 aa), 97% identity in aa 1 - 152. (152 aa)
yiiLPutative cytoplasmic protein; Involved in the anomeric conversion of L-rhamnose. (104 aa)
yneCPutative inner membrane protein; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD). (109 aa)
STM3461Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74737.1); Blastp hit to AAC74737.1 (101 aa), 65% identity in aa 3 - 100. (103 aa)
ygiNPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76065.1); Blastp hit to AAC76065.1 (104 aa), 90% identity in aa 1 - 104. (104 aa)
STM2446Putative iron-dependent peroxidase; Similar to E. coli orf, hypothetical protein (AAC75484.1); Blastp hit to AAC75484.1 (308 aa), 94% identity in aa 10 - 308. (299 aa)
yciIPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74333.1); Blastp hit to AAC74333.1 (130 aa), 91% identity in aa 33 - 130. (98 aa)
STM1001Similar to E. coli regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system (AAC73975.1); Blastp hit to AAC73975.1 (164 aa), 31% identity in aa 12 - 162. (153 aa)
ybaOSimilar to E. coli putative LRP-like transcriptional regulator (AAC73550.1); Blastp hit to AAC73550.1 (181 aa), 95% identity in aa 30 - 181. (152 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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