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proW proW malF malF malG malG pstC pstC pstA pstA dppB dppB dppC dppC ugpA ugpA ugpE ugpE cysU cysU cysW cysW hisQ hisQ hisM hisM yejE yejE yejB yejB yehY yehY yehW yehW yecS yecS oppB oppB oppC oppC sapC sapC sapB sapB STM1636 STM1636 STM1634 STM1634 osmY-2 osmY-2 osmW osmW STM1257 STM1257 STM1256 STM1256 potB potB potC potC artQ artQ artM artM potI potI potH potH yliD yliD yliC yliC glnP glnP modB modB gltJ gltJ gltK gltK sfbC sfbC phnU phnU phnV phnV yaeE yaeE yabK yabK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
proWGlycine/betaine/proline transport protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (354 aa)
malFMaltose transport protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. (514 aa)
malGMaltose transport protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. (296 aa)
pstCHigh-affinity phosphate transporter; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (319 aa)
pstAABC superfamily (membrane); similar to E. coli high-affinity phosphate-specific transport system (AAC76749.1); Blastp hit to AAC76749.1 (296 aa), 95% identity in aa 1 - 296. (296 aa)
dppBDipeptide transport protein 1; ABC superfamily (membrane); similar to E. coli dipeptide transport system permease protein 1 (AAC76568.1); Blastp hit to AAC76568.1 (339 aa), 97% identity in aa 1 - 339. (339 aa)
dppCDipeptide transport protein 2; ABC superfamily (membrane); similar to E. coli dipeptide transport system permease protein 2 (AAC76567.1); Blastp hit to AAC76567.1 (300 aa), 94% identity in aa 1 - 300. (300 aa)
ugpASn-glycerol 3-phosphate transport protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (295 aa)
ugpESn-glycerol 3-phosphate transport protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (281 aa)
cysUThiosulfate transport protein; Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane (By similarity). (277 aa)
cysWThiosulfate permease W protein; ABC superfamily (membrane); similar to E. coli sulfate transport system permease W protein (AAC75476.1); Blastp hit to AAC75476.1 (149 aa), 99% identity in aa 1 - 149. (291 aa)
hisQHistidine and lysine/arginine/ornithine transport system; Part of the histidine permease ABC transporter. Also part of a lysine/arginine/ornithine transporter. Probably responsible for the translocation of the substrate across the membrane. Required to relay the ATPase-inducing signal from the solute-binding protein to HisP. (228 aa)
hisMHistidine and lysine/arginine/ornithine transport protein; Part of the histidine permease ABC transporter. Also part of a lysine/arginine/ornithine transporter. Probably responsible for the translocation of the substrate across the membrane. Required to relay the ATPase-inducing signal from the solute-binding protein to HisP. (235 aa)
yejEPutative ABC-type dipeptide/oligopeptide/nickel transport systems, permease component; Similar to E. coli putative transport system permease protein (AAC75240.1); Blastp hit to AAC75240.1 (341 aa), 91% identity in aa 1 - 341. (341 aa)
yejBPutative ABC-type dipeptide/oligopeptide/nickel transport systems, permease component; Similar to E. coli putative transport system permease protein (AAC75239.1); Blastp hit to AAC75239.1 (364 aa), 96% identity in aa 1 - 364. (364 aa)
yehYPutative ABC-type proline/glycine betaine transport system, permease component; Similar to E. coli putative transport system permease protein (AAC75191.1); Blastp hit to AAC75191.1 (385 aa), 76% identity in aa 6 - 385. (389 aa)
yehWPutative ABC-type proline/glycine betaine transport system, permease component; Similar to E. coli putative transport system permease protein (AAC75189.1); Blastp hit to AAC75189.1 (243 aa), 84% identity in aa 1 - 243. (243 aa)
yecSPutative ABC-type amino acid transporter; Permease component; similar to E. coli putative transport system permease protein (former yecC) (AAC74985.1); Blastp hit to AAC74985.1 (222 aa), 93% identity in aa 1 - 222. (222 aa)
oppBOligopeptide transport protein; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily. (306 aa)
oppCOligopeptide transport protein; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily. (302 aa)
sapCABC superfamily peptide transport protein; Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily. (296 aa)
sapBABC superfamily peptide transport protein; Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides. (321 aa)
STM1636Similar to E. coli putative transport system permease protein (former yecC) (AAC74985.1); Blastp hit to AAC74985.1 (222 aa), 34% identity in aa 10 - 216. (226 aa)
STM1634Putative amino acid ABC transporter permease component; Similar to E. coli putative transport system permease protein (former yecC) (AAC74985.1); Blastp hit to AAC74985.1 (222 aa), 31% identity in aa 14 - 213. (215 aa)
osmY-2ABC-type transport system protein; Part of the OsmU ABC transporter complex, which is involved in the uptake of osmoprotectants such as choline-O-sulfate and glycine betaine. Probably responsible for the translocation of the substrate across the membrane. (236 aa)
osmWPutative binding-protein-dependent transport system; Part of the OsmU ABC transporter complex, which is involved in the uptake of osmoprotectants such as choline-O-sulfate and glycine betaine. Probably responsible for the translocation of the substrate across the membrane. (215 aa)
STM1257Putative ABC transporter; Putative transmembrane protein (gi|2337944). (270 aa)
STM1256Putative ABC transporter; Putative transmembrane protein (gi|2337943). (324 aa)
potBSpermidine/putrescine transporter; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (287 aa)
potCSpermidine/putrescine transporter; ABC superfamily (membrane); similar to E. coli spermidine/putrescine transport system permease (AAC74208.1); Blastp hit to AAC74208.1 (264 aa), 96% identity in aa 1 - 258. (259 aa)
artQArginine 3rd transport system; ABC superfamily (membrane); similar to E. coli arginine 3rd transport system permease protein (AAC73949.1); Blastp hit to AAC73949.1 (238 aa), 94% identity in aa 1 - 237. (238 aa)
artMArginine 3rd transport system; ABC superfamily (membrane); similar to E. coli arginine 3rd transport system permease protein (AAC73948.1); Blastp hit to AAC73948.1 (222 aa), 94% identity in aa 1 - 222. (222 aa)
potIPutrescine transporter; ABC superfamily (membrane); similar to E. coli putrescine transport protein; permease (AAC73944.1); Blastp hit to AAC73944.1 (281 aa), 94% identity in aa 1 - 281. (281 aa)
potHPutrescine transporter; ABC superfamily (membrane); similar to E. coli putrescine transport protein; permease (AAC73943.1); Blastp hit to AAC73943.1 (317 aa), 92% identity in aa 1 - 317. (317 aa)
yliDPutative ABC transporter inner membrane component; Part of the ABC transporter complex GsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane. (303 aa)
yliCPutative ABC transporter periplasmic binding protein; Part of the ABC transporter complex GsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane. (306 aa)
glnPABC superfamily (membrane); similar to E. coli glutamine high-affinity transport system; membrane component (AAC73897.1); Blastp hit to AAC73897.1 (219 aa), 96% identity in aa 1 - 219. (219 aa)
modBMolybdate transporter; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (229 aa)
gltJGlutamate/aspartate transporter; ABC superfamily (membrane); similar to E. coli glutamate/aspartate transport system permease (AAC73755.1); Blastp hit to AAC73755.1 (246 aa), 94% identity in aa 1 - 246. (246 aa)
gltKGlutamate/aspartate transporter; ABC superfamily (membrane); similar to E. coli glutamate/aspartate transport system permease (AAC73754.1); Blastp hit to AAC73754.1 (224 aa), 95% identity in aa 1 - 223. (224 aa)
sfbCPutative binding-protein-dependent transport systems inner membrane component; Similar to E. coli putative transport system permease protein (AAC73309.1); Blastp hit to AAC73309.1 (217 aa), 44% identity in aa 15 - 217. (219 aa)
phnU2-aminoethylphosphonate transporter, memrane component; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. (286 aa)
phnV2-aminoethylphosphonate transporter, memrane component; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. (265 aa)
yaeEPutative ABC superfamily (membrane) transport protein; Part of the binding-protein-dependent transport system for D- methionine and the toxic methionine analog alpha-methyl-methionine. Probably responsible for the translocation of the substrate across the membrane (By similarity). (217 aa)
yabKPutative binding-protein-dependent transport system inner membrane component; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Is also involved in thiamine pyrophosphate transport. (536 aa)
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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