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| | xapR | Regulator for XapA; LysR family; similar to E. coli regulator for xapA (AAC75458.1); Blastp hit to AAC75458.1 (294 aa), 80% identity in aa 1 - 293; Belongs to the LysR transcriptional regulatory family. (294 aa) |
| | ptsJ | Putative gntR family regulatory protein; Acts as transcriptional repressor of the pdxK gene, encoding a pyridoxal kinase involved in the vitamin B6 salvage pathway. Also represses transcription of its own gene. Binds to the ptsJ-pdxK intergenic region, but does not bind pdxY and pdxH promoters. Among all six B6 vitamers, only pyridoxal 5'-phosphate (PLP) clearly binds to the protein and acts as an effector molecule for PtsJ, inducing a protein conformational change that increases affinity for DNA. Thus, PLP stabilizes protein-DNA interactions, reinforcing repression. In the C-terminal [...] (430 aa) |
| | eutK | Putative carboxysome structural protein; May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place; Belongs to the bacterial microcompartments protein family. (164 aa) |
| | yfhP | Hypothetical protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. (164 aa) |
| | cadC | OmpR family; similar to E. coli transcriptional activator of cad operon (AAC77094.1); Blastp hit to AAC77094.1 (512 aa), 58% identity in aa 1 - 512. (514 aa) |
| | yfhH | Putative ABC superfamily transport protein; Membrane; similar to E. coli orf, hypothetical protein (AAC75614.1); Blastp hit to AAC75614.1 (306 aa), 83% identity in aa 25 - 306. (282 aa) |
| | STM2575 | Putative LysR family transcriptional regulator; Similar to E. coli cyn operon positive regulator (AAC73441.1); Blastp hit to AAC73441.1 (299 aa), 30% identity in aa 4 - 229; Belongs to the LysR transcriptional regulatory family. (308 aa) |
| | STM2609 | Gifsy-1 prophage protein; Similar to DNA packaging protein Nu1 of phage 21; similar to E. coli homolog of Qin prophage packaging protein NU1 (AAC74621.1); Blastp hit to AAC74621.1 (189 aa), 58% identity in aa 1 - 162. (181 aa) |
| | rpoE | Sigma E (sigma 24) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase (RNAP) to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma-E controls the envelope stress response, responding to periplasmic protein stress, increased levels of periplasmic lipopolysaccharide (LPS) as well as acid stress, heat shock and oxidative stress; it controls protein processing in the extracytoplasmic compartment (By similarity). (191 aa) |
| | yfiE | Similar to E. coli putative transcriptional regulator LYSR-type (AAC75630.1); Blastp hit to AAC75630.1 (308 aa), 78% identity in aa 16 - 305; Belongs to the LysR transcriptional regulatory family. (299 aa) |
| | STM2765 | Putative transposase. (88 aa) |
| | tctD | Tricarboxylic transport regulatory protein; Transcriptional activator of the tctI tricarboxylate transport system operon. (224 aa) |
| | ygaE | Putative GntR family transcriptional repressor; Similar to E. coli putative transcriptional regulator (AAC75711.1); Blastp hit to AAC75711.1 (226 aa), 87% identity in aa 10 - 225. (225 aa) |
| | STM2797 | Putative arsR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC75714.1); Blastp hit to AAC75714.1 (99 aa), 89% identity in aa 1 - 99. (99 aa) |
| | STM2803 | Putative gntR family regulatory protein; Similar to E. coli putative regulator (AAC77296.1); Blastp hit to AAC77296.1 (470 aa), 31% identity in aa 119 - 437, 27% identity in aa 1 - 224. (444 aa) |
| | emrR | Transcriptional repressor of emrAB operon; MarR family; similar to E. coli regulator of plasmid mcrB operon (microcin B17 synthesis) (AAC75731.1); Blastp hit to AAC75731.1 (176 aa), 93% identity in aa 1 - 175. (176 aa) |
| | oraA | Regulator; Modulates RecA activity; Belongs to the RecX family. (166 aa) |
| | srlR | DeoR family; similar to E. coli regulator for gut (srl), glucitol operon (AAC75749.1); Blastp hit to AAC75749.1 (257 aa), 94% identity in aa 1 - 257. (257 aa) |
| | hilA | Invasion genes transcription activator; The main transcriptional regulator of the Salmonella pathogenicity island 1 (SPI1) gene expression. Activates the expression of invasion genes by a direct action at their promoters and also indirectly by increasing the level of InvF. Also binds upstream of prgH and directly activates the expression of prgHIJK operon. (553 aa) |
| | STM2912 | Similar to E. coli putative transcriptional regulator LYSR-type (AAC73313.1); Blastp hit to AAC73313.1 (304 aa), 32% identity in aa 6 - 289; Belongs to the LysR transcriptional regulatory family. (310 aa) |
| | ygbI | Putative regulatory protein, deoR family; Similar to E. coli putative DEOR-type transcriptional regulator (AAC75777.1); Blastp hit to AAC75777.1 (265 aa), 86% identity in aa 11 - 263. (254 aa) |
| | STM2920 | Similar to E. coli transcriptional regulator for cryptic hemolysin (AAC74714.1); Blastp hit to AAC74714.1 (146 aa), 27% identity in aa 1 - 135. (134 aa) |
| | rpoS | Sigma S (sigma 38) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. (330 aa) |
| | fucR | DeoR family; similar to E. coli positive regulator of the fuc operon (AAC75847.1); Blastp hit to AAC75847.1 (243 aa), 88% identity in aa 1 - 235. (236 aa) |
| | gcvA | Regulator of gcv operon; LysR family; similar to E. coli positive regulator of gcv operon (AAC75850.1); Blastp hit to AAC75850.1 (305 aa), 98% identity in aa 1 - 305; Belongs to the LysR transcriptional regulatory family. (305 aa) |
| | lysR | Positive LysR family transcriptional regulator; Similar to E. coli positive regulator for lys (AAC75878.1); Blastp hit to AAC75878.1 (311 aa), 86% identity in aa 1 - 311; Belongs to the LysR transcriptional regulatory family. (311 aa) |
| | STM3020 | Similar to E. coli putative transcriptional regulator LYSR-type (AAC73606.1); Blastp hit to AAC73606.1 (308 aa), 26% identity in aa 2 - 275; Belongs to the LysR transcriptional regulatory family. (287 aa) |
| | iciA | Inhibitor of replication initiation; Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. (297 aa) |
| | STM3084 | Putative gntR family regulatory protein; Similar to E. coli regulator for uxu operon (AAC77280.1); Blastp hit to AAC77280.1 (257 aa), 39% identity in aa 8 - 247. (266 aa) |
| | STM3098 | Putative transcriptional regulator. (228 aa) |
| | STM3121 | Putative transcriptional regulator (gi|5852589); Belongs to the LysR transcriptional regulatory family. (292 aa) |
| | STM3124 | Putative response regulator; Contains a CheY-like receiver domain and a HTH DNA-binding domain; similar to E. coli putative regulator (AAC76545.1); Blastp hit to AAC76545.1 (200 aa), 48% identity in aa 138 - 200. (227 aa) |
| | ygiX | Putative transcriptional regulator; Member of a two-component regulatory system QseB/QseC. Activates the flagella regulon by activating transcription of flhDC (By similarity). (219 aa) |
| | rpoD | Sigma D factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (660 aa) |
| | yqjI | Putative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC76106.1); Blastp hit to AAC76106.1 (207 aa), 68% identity in aa 1 - 207. (215 aa) |
| | yhaJ | Similar to E. coli putative transcriptional regulator LYSR-type (AAC76140.1); Blastp hit to AAC76140.1 (298 aa), 96% identity in aa 1 - 298; Belongs to the LysR transcriptional regulatory family. (298 aa) |
| | tdcA | LysR family; similar to E. coli transcriptional activator of tdc operon (AAC76153.1); Blastp hit to AAC76153.1 (312 aa), 89% identity in aa 1 - 311; Belongs to the LysR transcriptional regulatory family. (312 aa) |
| | agaR | Aga operon transcriptional repressor; DeoR family; similar to E. coli putative DEOR-type transcriptional regulator of aga operon (AAC76165.1); Blastp hit to AAC76165.1 (269 aa), 26% identity in aa 10 - 252. (277 aa) |
| | STM3262 | Transcriptional regulator of sugar metabolism; Similar to E. coli split galactitol utilization operon repressor, interrupted (AAC75148.1); Blastp hit to AAC75148.1 (148 aa), 77% identity in aa 1 - 148. (257 aa) |
| | yhcK | Putative gntR family regulatory protein; Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids. (263 aa) |
| | STM3357 | Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC74613.1); Blastp hit to AAC74613.1 (228 aa), 23% identity in aa 15 - 214. (221 aa) |
| | STM3358 | Putative gntR family regulatory protein. (209 aa) |
| | argR | Repressor of arg regulon; Negatively controls the expression of the four operons of arginine biosynthesis in addition to the carAB operon. Predominantly interacts with A/T residues in ARG boxes; Belongs to the ArgR family. (156 aa) |
| | yhcS | Similar to E. coli putative transcriptional regulator LYSR-type (AAC76275.1); Blastp hit to AAC76275.1 (309 aa), 95% identity in aa 1 - 309; Belongs to the LysR transcriptional regulatory family. (309 aa) |
| | smf | Putative protein involved in DNA uptake; Similar to E. coli orf, fragment 1 (AAC76311.1); Blastp hit to AAC76311.1 (253 aa), 66% identity in aa 1 - 248. (374 aa) |
| | crp | Catabolite activator protein (CAP); A global transcription regulator. Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding to regulate transcription. It can act as an activator, repressor, coactivator or corepressor. Induces a severe bend in DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP. Plays a major role in carbon catabolite repression (CCR) (By similarity). (210 aa) |
| | ompR | Response regulator in two-component regulatory system with EnvZ; Member of the two-component regulatory system EnvZ/OmpR involved in osmoregulation (particularly of genes ompF and ompC) as well as other genes (By similarity). Plays a central role in both acid and osmotic stress responses. Binds to the promoter of both ompC and ompF; at low osmolarity it activates ompF transcription, while at high osmolarity it represses ompF and activates ompC transcription (By similarity). (239 aa) |
| | yhgG | Putative cytoplasmic protein; May function as a transcriptional regulator that controls feoABC expression. (78 aa) |
| | malT | Transcriptional activator of the mal genes; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box. (901 aa) |
| | glpR | DeoR family; similar to E. coli repressor of the glp operon (AAC76448.1); Blastp hit to AAC76448.1 (252 aa), 93% identity in aa 1 - 252. (252 aa) |
| | STM3533 | Similar to E. coli putative regulator (AAC75308.1); Blastp hit to AAC75308.1 (260 aa), 38% identity in aa 4 - 249. (251 aa) |
| | rbsK-2 | Putative transcriptional regulator of sugar metabolism; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (404 aa) |
| | STM3602 | Putative gntR family regulatory protein; Similar to E. coli putative transcriptional regulator (AAC76400.1); Blastp hit to AAC76400.1 (265 aa), 28% identity in aa 27 - 260. (239 aa) |
| | yhjB | LuxR/UhpA family; similar to E. coli putative regulator (AAC76545.1); Blastp hit to AAC76545.1 (200 aa), 72% identity in aa 1 - 200. (200 aa) |
| | yhjC | Similar to E. coli putative transcriptional regulator LYSR-type (AAC76546.1); Blastp hit to AAC76546.1 (323 aa), 66% identity in aa 25 - 320; Belongs to the LysR transcriptional regulatory family. (299 aa) |
| | yiaJ | IclR family transcriptional repressor; Similar to E. coli putative regulator (AAC76598.1); Blastp hit to AAC76598.1 (282 aa), 91% identity in aa 16 - 276. (266 aa) |
| | selB | Similar to E. coli selenocysteinyl-tRNA-specific translation factor (AAC76614.1); Blastp hit to AAC76614.1 (614 aa), 85% identity in aa 1 - 614. (616 aa) |
| | lldR | Putative transcriptional GntR family regulator for lct operon; Similar to E. coli transcriptional regulator (AAC76628.1); Blastp hit to AAC76628.1 (258 aa), 86% identity in aa 1 - 258. (258 aa) |
| | STM3736 | Similar to E. coli putative transcriptional regulator LYSR-type (AAC73730.1); Blastp hit to AAC73730.1 (266 aa), 25% identity in aa 2 - 219; Belongs to the LysR transcriptional regulatory family. (300 aa) |
| | marT | Pathogenicity island encoded protein: SPI3; putative transcriptional regulator MarT (gi|4324612). (285 aa) |
| | STM3785 | Putative gntR family regulatory protein; Similar to E. coli transcriptional regulator of succinylCoA synthetase operon (AAC73824.1); Blastp hit to AAC73824.1 (240 aa), 31% identity in aa 3 - 216. (247 aa) |
| | dsdC | LysR family transcriptional activator; Similar to E. coli D-serine dehydratase (deaminase) transcriptional activator (AAC75423.1); Blastp hit to AAC75423.1 (311 aa), 90% identity in aa 1 - 307; Belongs to the LysR transcriptional regulatory family. (307 aa) |
| | torR | Two-component system, OmpR family, torCAD operon response regulator TorR; Regulates tor operon (TorR family); similar to E. coli response transcriptional regulator for torA (sensor TorS) (AAC74080.1); Blastp hit to AAC74080.1 (230 aa), 81% identity in aa 1 - 229. (230 aa) |
| | dgoR | Galactonate operon transcriptional repressor; GntR family; similar to E. coli regulator protein for dgo operon (AAC76718.1); Blastp hit to AAC76718.1 (128 aa), 94% identity in aa 1 - 112. (229 aa) |
| | STM3834 | Similar to E. coli putative transcriptional regulator LYSR-type (AAC73855.1); Blastp hit to AAC73855.1 (338 aa), 27% identity in aa 22 - 318; Belongs to the LysR transcriptional regulatory family. (298 aa) |
| | yidZ | Putative LysR family transcriptional regulator; Involved in anaerobic NO protection. (319 aa) |
| | asnC | AsnC family; similar to E. coli regulator for asnA, asnC and gidA (AAC76766.1); Blastp hit to AAC76766.1 (152 aa), 97% identity in aa 1 - 152. (152 aa) |
| | yieP | Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC76778.1); Blastp hit to AAC76778.1 (181 aa), 82% identity in aa 1 - 181. (234 aa) |
| | yifA | Putative LysR family transcriptional regulator; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon. (282 aa) |
| | ilvY | Positive LysR family regulator for ilvC; This protein activates the transcription of the IlvC gene in the presence of acetolactate or acetohydroxybutyrate. IlvY is also a negative regulator of its own expression; Belongs to the LysR transcriptional regulatory family. (295 aa) |
| | recQ | ATP-dependent DNA helicase; Involved in the RecF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase; Belongs to the helicase family. RecQ subfamily. (615 aa) |
| | metR | Regulator for metE and metH; Control of the last step in methionine biosynthesis; MetR is a positive activator of the metA, metE and metH genes. It is also a negative regulator of its own expression; Belongs to the LysR transcriptional regulatory family. (317 aa) |
| | yihW | Putative glycerol-3-phosphate regulon repressor; DeoR family; similar to E. coli putative DEOR-type transcriptional regulator (AAD13446.1); Blastp hit to AAD13446.1 (269 aa), 89% identity in aa 9 - 263. (267 aa) |
| | cpxR | Response reguator in two-component regulatory system with CpxA; Regulates expression of protein folding and degrading factors (OmpR family); similar to E. coli transcriptional regulator in 2-component system (AAC76894.1); Blastp hit to AAC76894.1 (232 aa), 97% identity in aa 1 - 232. (232 aa) |
| | STM4068 | Putative gntR family regulatory protein; Similar to E. coli transcriptional regulator of succinylCoA synthetase operon (AAC73824.1); Blastp hit to AAC73824.1 (240 aa), 28% identity in aa 5 - 220. (240 aa) |
| | ydeW | Putative transcriptional repressor; In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFGE operon and its own transcription. In the presence of AI-2, LsrR is inactivated by binding phospho-AI-2, leading to the transcription of the lsr genes. (319 aa) |
| | oxyR | Regulatory protein sensor for oxidative stress; Regulates intracellular hydrogen peroxide (LysR family); similar to E. coli activator, hydrogen peroxide-inducible genes (AAC76943.1); Blastp hit to AAC76943.1 (305 aa), 95% identity in aa 1 - 305; Belongs to the LysR transcriptional regulatory family. (305 aa) |
| | birA | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. (320 aa) |
| | iclR | Acetate operon transcriptional repressor; Regulation of the glyoxylate bypass operon, which encodes isocitrate lyase, malate synthase as well as isocitrate dehydrogenase kinase/phosphorylase. (274 aa) |
| | lexA | SOS response regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single- stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (202 aa) |
| | zur | Transcriptional repressor of znuABC operon; Fur family; similar to E. coli putative regulator (AAC77016.1); Blastp hit to AAC77016.1 (191 aa), 92% identity in aa 21 - 191; Belongs to the Fur family. (171 aa) |
| | STM4270 | Putative LysR family transcriptional regulator; Similar to E. coli activator, hydrogen peroxide-inducible genes (AAC76943.1); Blastp hit to AAC76943.1 (305 aa), 28% identity in aa 1 - 275; Belongs to the LysR transcriptional regulatory family. (295 aa) |
| | basR | Response regulator in two-component regulatory system with BasS; Member of the two-component regulatory system BasS/BasR. BasR induces the transcription of the ugd, ais, arnBCADTEF and eptA-basRS loci, all involved in resistance to polymyxin. Represses the transcription of pmrD. Plays a role in the adaptation of the organism to the host environment, in particular to neutrophils, and therefore it plays a role in virulence as well. (222 aa) |
| | STM4314 | Putative luxR family bacterial regulatory proteins. (95 aa) |
| | ecnR | Putative luxR family bacterial regulatory protein. (195 aa) |
| | yjeB | Putative negative regulator; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. Represses hmp expression under conditions of elevated intracellular iron concentrations, in the absence of nitric oxide. (141 aa) |
| | yjfQ | Putative transcriptional repressor; Represses ulaG and the ulaABCDEF operon. (251 aa) |
| | ytfH | Putative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC77169.1); Blastp hit to AAC77169.1 (156 aa), 90% identity in aa 35 - 152. (128 aa) |
| | STM4417 | Putative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC75614.1); Blastp hit to AAC75614.1 (306 aa), 25% identity in aa 31 - 278. (277 aa) |
| | STM4448 | Putative phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). (637 aa) |
| | argR-2 | Putative arginine repressor; Regulates arginine biosynthesis genes. (162 aa) |
| | uxuR | Similar to E. coli regulator for uxu operon (AAC77280.1); Blastp hit to AAC77280.1 (257 aa), 89% identity in aa 1 - 257. (257 aa) |
| | yjiE | Similar to E. coli putative transcriptional regulator LYSR-type (AAC77283.1); Blastp hit to AAC77283.1 (303 aa), 81% identity in aa 1 - 302; Belongs to the LysR transcriptional regulatory family. (302 aa) |
| | yjjQ | Putative LuxR/UhpA family transcriptional regulator; Similar to E. coli putative regulator (AAC77321.1); Blastp hit to AAC77321.1 (241 aa), 66% identity in aa 1 - 241. (241 aa) |
| | creB | Response regulator in two-component regulatory system with CreC; OmpR family; similar to E. coli catabolic regulation response regulator (AAC77351.1); Blastp hit to AAC77351.1 (229 aa), 83% identity in aa 1 - 229. (229 aa) |
| | arcA | Response regulator (OmpR family) in two-component regulatory system with ArcB (or CpxA); Regulates genes in aerobic pathways; similar to E. coli negative response regulator of genes in aerobic pathways, (sensors, ArcB and CpxA) (AAC77354.1); Blastp hit to AAC77354.1 (238 aa), 99% identity in aa 1 - 238. (238 aa) |
| | STM0014 | Similar to E. coli putative transcriptional regulator LYSR-type (AAC73704.1); Blastp hit to AAC73704.1 (300 aa), 25% identity in aa 8 - 296; Belongs to the LysR transcriptional regulatory family. (315 aa) |
| | STM0017 | Similar to E. coli putative sensory transducer (AAC75886.1); Blastp hit to AAC75886.1 (269 aa), 30% identity in aa 3 - 109. (147 aa) |
| | STM0029 | Putative transcriptional regulator MarT (gi|4324612). (149 aa) |
| | STM0030 | Putative LysR family transcriptional regulator; leuO homolog (gi|6650098); Belongs to the LysR transcriptional regulatory family. (334 aa) |
| | STM0031 | Putative transcriptional regulator MarT (gi|4324612). (146 aa) |
| | nhaR | LysR family; similar to E. coli transcriptional activator of nhaA (AAC73131.1); Blastp hit to AAC73131.1 (301 aa), 92% identity in aa 1 - 296; Belongs to the LysR transcriptional regulatory family. (299 aa) |
| | caiF | Similar to E. coli transcriptional regulator of cai operon (AAC73145.1); Blastp hit to AAC73145.1 (166 aa), 76% identity in aa 36 - 166. (131 aa) |
| | leuO | Putative LysR family transcriptional regulator; Probable activator protein in leuabcd operon. (SW:LEUO_SALTY); Belongs to the LysR transcriptional regulatory family. (314 aa) |
| | pdhR | Transcriptional repressor for pyruvate dehydrogenase complex (GntR family); Transcriptional repressor for the pyruvate dehydrogenase complex genes aceEF and lpd. (254 aa) |
| | yafC | Similar to E. coli putative transcriptional regulator LYSR-type (AAC73313.1); Blastp hit to AAC73313.1 (304 aa), 90% identity in aa 1 - 303; Belongs to the LysR transcriptional regulatory family. (304 aa) |
| | sinR | Transcriptional regulator; Probable regulatory protein. Its target is not known. (315 aa) |
| | STM0333 | Similar to E. coli putative transcriptional regulator LYSR-type (AAC74869.1); Blastp hit to AAC74869.1 (314 aa), 44% identity in aa 2 - 307; Belongs to the LysR transcriptional regulatory family. (321 aa) |
| | STM0344 | Putative response regulator. (247 aa) |
| | STM0347 | Putative response regulator; Unknown (gi|6707275). (213 aa) |
| | phoB | Regulates pho regulon (OmpR family); similar to E. coli positive response regulator for pho regulon, sensor is PhoR (or CreC) (AAC73502.1); Blastp hit to AAC73502.1 (229 aa), 95% identity in aa 1 - 229. (229 aa) |
| | STM0410 | Putative regulatory protein. (230 aa) |
| | phnR | 2-aminoethylphosphonate transport, repressor; Probable repressor protein of GntR family phnR (gi|11354257). (239 aa) |
| | ybaO | Similar to E. coli putative LRP-like transcriptional regulator (AAC73550.1); Blastp hit to AAC73550.1 (181 aa), 95% identity in aa 30 - 181. (152 aa) |
| | ybaZ | Putative methyltransferase; Similar to E. coli orf, hypothetical protein (AAC73557.1); Blastp hit to AAC73557.1 (129 aa), 82% identity in aa 1 - 129. (129 aa) |
| | ybbS | Putative LysR family transcriptional regulator; Positive regulator essential for the expression of allD operon. Binds to the allD promoter (By similarity). (308 aa) |
| | allR | Putative regulatory protein; Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS-allA intergenic region (By similarity). (272 aa) |
| | fimW | Putative fimbrial protein; Fimbriae W protein. (SW:FIMW_SALTY). (198 aa) |
| | ybdO | Similar to E. coli putative transcriptional regulator LYSR-type (AAC73704.1); Blastp hit to AAC73704.1 (300 aa), 54% identity in aa 1 - 298; Belongs to the LysR transcriptional regulatory family. (300 aa) |
| | ybeF | Similar to E. coli putative transcriptional regulator LYSR-type (AAC73730.1); Blastp hit to AAC73730.1 (266 aa), 68% identity in aa 1 - 266; Belongs to the LysR transcriptional regulatory family. (317 aa) |
| | nagC | Similar to E. coli transcriptional repressor of nag (N-acetylglucosamine) operon (AAC73770.1); Blastp hit to AAC73770.1 (406 aa), 94% identity in aa 1 - 406. (406 aa) |
| | STM0692 | Putative LysR family transcriptional regulator; Similar to E. coli nitrogen assimilation control protein (AAC75050.1); Blastp hit to AAC75050.1 (305 aa), 32% identity in aa 1 - 301; Belongs to the LysR transcriptional regulatory family. (308 aa) |
| | fur | Transcriptional repressor of iron-responsive genes (Fur family) (ferric uptake regulator); Similar to E. coli negative regulator (AAC73777.1); Blastp hit to AAC73777.1 (148 aa), 99% identity in aa 1 - 146; Belongs to the Fur family. (150 aa) |
| | kdpE | Response regulator in two-component regulatory system with KdpD; Regulates kdp operon encoding a high-affinity K translocating ATPase (OmpR family); similar to E. coli regulator of kdp operon (transcriptional effector) (AAC73788.1); Blastp hit to AAC73788.1 (225 aa), 91% identity in aa 1 - 224. (225 aa) |
| | STM0763 | Transcriptional regulator, lysR family; Similar to E. coli cyn operon positive regulator (AAC73441.1); Blastp hit to AAC73441.1 (299 aa), 25% identity in aa 16 - 288; Belongs to the LysR transcriptional regulatory family. (283 aa) |
| | STM0764 | Similar to E. coli putative transcriptional regulator LYSR-type (AAC77283.1); Blastp hit to AAC77283.1 (303 aa), 30% identity in aa 9 - 300; Belongs to the LysR transcriptional regulatory family. (327 aa) |
| | modE | Transcriptional repressor of modABCD operon (molybdate uptake); Similar to E. coli molybdate uptake regulatory protein (AAC73848.1); Blastp hit to AAC73848.1 (262 aa), 89% identity in aa 1 - 262. (262 aa) |
| | hutC | Histidine utilization repressor; Similar to E. coli transcriptional regulator of succinylCoA synthetase operon (AAC73824.1); Blastp hit to AAC73824.1 (240 aa), 24% identity in aa 5 - 229. (241 aa) |
| | mntR | Putative Mn-dependent transcriptional regulator; In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP (By similarity). Belongs to the DtxR/MntR family. (157 aa) |
| | STM0859 | Similar to E. coli putative transcriptional regulator LYSR-type (AAC74667.1); Blastp hit to AAC74667.1 (297 aa), 28% identity in aa 1 - 264; Belongs to the LysR transcriptional regulatory family. (296 aa) |
| | STM0948 | Putative cytoplasmic protein. (133 aa) |
| | STM0952 | Similar to E. coli putative transcriptional regulator LYSR-type (AAC73313.1); Blastp hit to AAC73313.1 (304 aa), 31% identity in aa 1 - 291; Belongs to the LysR transcriptional regulatory family. (303 aa) |
| | lrp | Regulator for lrp regulon and high-affinity branched-chain amino acid transport system; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes. (164 aa) |
| | ftsK | Cell division protein; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA trans [...] (1351 aa) |
| | mukF | mukF protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. (440 aa) |
| | STM1001 | Similar to E. coli regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system (AAC73975.1); Blastp hit to AAC73975.1 (164 aa), 31% identity in aa 12 - 162. (153 aa) |
| | STM1014 | Gifsy-2 prophage putative regulatory protein; Probable replication protein (gi|7467283). (327 aa) |
| | STM1016 | Gifsy-2 prophage protein; Hypothetical protein (gi|7467246). (115 aa) |
| | copR | Copper resistance transcriptional regulatory protein; Pathogenicity island encoded protein: SPI5; similar to E. coli putative 2-component transcriptional regulator (AAC75035.1); Blastp hit to AAC75035.1 (239 aa), 74% identity in aa 6 - 236. (248 aa) |
| | hpaR | 4-hydroxyphenylacetate catabolism protein. (146 aa) |
| | STM1127 | Putative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC75480.1); Blastp hit to AAC75480.1 (285 aa), 29% identity in aa 15 - 264. (293 aa) |
| | csgD | Putative transcriptional regulator; Necessary for transcription of the csgAB operon. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription (By similarity). (216 aa) |
| | yceH | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74151.1); Blastp hit to AAC74151.1 (215 aa), 86% identity in aa 1 - 215; Belongs to the UPF0502 family. (215 aa) |
| | phoP | Response regulator in two-component regulatory system with PhoQ; Member of the two-component regulatory system PhoP/PhoQ which regulates the expression of genes involved in virulence, adaptation to acidic and low Mg(2+) environments and resistance to host defense antimicrobial peptides. Essential for intramacrophage survival of S.typhimurium. In low periplasmic Mg(2+), PhoQ phosphorylates PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG). In high periplasmic Mg(2+), PhoQ dephosphorylates phospho-PhoP, resulting in the repressio [...] (224 aa) |
| | STM1265 | Putative response regulators; Contains a CheY-like receiver domain and a HTH DNA-binding domain. (197 aa) |
| | orf408 | Putative regulatory protein, deoR family; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (408 aa) |
| | ttrR | Tetrathionate reductase complex: response regulator; Member of the two-component regulatory system TtrR/TtrS, which is required for synthesis of tetrathionate reductase. Positively regulates transcription of the ttrBCA operon. During mice infection, the ability to use tetrathionate as an electron acceptor is a growth advantage for S.typhimurium over the competing microbiota in the lumen of the inflamed gut. (206 aa) |
| | ydhB | Similar to E. coli putative transcriptional regulator LYSR-type (AAC74731.1); Blastp hit to AAC74731.1 (310 aa), 90% identity in aa 1 - 310; Belongs to the LysR transcriptional regulatory family. (310 aa) |
| | slyA | MarR family transcriptional regulator for hemolysin; Transcription regulator that can specifically activate or repress expression of target genes. Required for virulence and survival in the macrophage environment. Probably activates expression of ispA, xseB genes, and of omp operon. (146 aa) |
| | rstA | Similar to E. coli response transcriptional regulatory protein (RstB sensor) (AAC74680.1); Blastp hit to AAC74680.1 (242 aa), 84% identity in aa 4 - 242. (243 aa) |
| | ynfL | Similar to E. coli putative transcriptional regulator LYSR-type (AAC74667.1); Blastp hit to AAC74667.1 (297 aa), 83% identity in aa 1 - 297; Belongs to the LysR transcriptional regulatory family. (299 aa) |
| | mlc | Transcriptional repressor of ptsG and ptsHI; Global repressor of carbohydrate metabolism (pts operon) (NagC/XylR family); similar to E. coli putative NAGC-like transcriptional regulator (AAC74666.1); Blastp hit to AAC74666.1 (406 aa), 90% identity in aa 1 - 406. (406 aa) |
| | ydfH | Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC74613.1); Blastp hit to AAC74613.1 (228 aa), 86% identity in aa 1 - 228. (228 aa) |
| | marR | Transcriptional repressor of marRAB operon; Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site. (144 aa) |
| | yneJ | Similar to E. coli putative transcriptional regulator LYSR-type (AAC74599.1); Blastp hit to AAC74599.1 (293 aa), 84% identity in aa 1 - 283; Belongs to the LysR transcriptional regulatory family. (290 aa) |
| | STM1541 | Putative gntR family regulatory protein; Similar to E. coli regulator for uxu operon (AAC77280.1); Blastp hit to AAC77280.1 (257 aa), 31% identity in aa 8 - 229. (263 aa) |
| | STM1547 | Putative marR-family transcriptional regulator. (162 aa) |
| | yncC | Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC74532.1); Blastp hit to AAC74532.1 (240 aa), 58% identity in aa 20 - 238. (221 aa) |
| | ydcR | Putative gntR family regulatory protein; Similar to E. coli multi modular; putative transcriptional regulator; also putative ATP-binding component of a transport system (AAC74521.1); Blastp hit to AAC74521.1 (468 aa), 87% identity in aa 1 - 468. (474 aa) |
| | ydcI | Similar to E. coli putative transcriptional regulator LYSR-type (AAC74504.1); Blastp hit to AAC74504.1 (354 aa), 83% identity in aa 48 - 353; Belongs to the LysR transcriptional regulatory family. (307 aa) |
| | ogt | O-6-alkylguanine-DNA; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (171 aa) |
| | fnr | Transcriptional regulator; Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metabolism. When the terminal electron acceptor, O(2), is no longer available, it represses the synthesis of enzymes involved in aerobic respiration and increases the synthesis of enzymes required for anaerobic respiration (By similarity). (264 aa) |
| | STM1677 | Similar to E. coli putative transcriptional regulator LYSR-type (AAC76546.1); Blastp hit to AAC76546.1 (323 aa), 35% identity in aa 25 - 313; Belongs to the LysR transcriptional regulatory family. (301 aa) |
| | yciT | Putative deoR family regulatory protein; Similar to E. coli putative DEOR-type transcriptional regulator (AAC74366.1); Blastp hit to AAC74366.1 (249 aa), 82% identity in aa 1 - 247. (250 aa) |
| | cysB | Transcriptional regulator for cysteine regulon; This protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of L-cysteine from inorganic sulfate. The inducer for CysB is N-acetylserine. CysB inhibits its own transcription. (324 aa) |
| | narL | Response regulator in two-component regulatory system with NarX (or NarQ); Regulates anaerobic respiration and fermentation (LuxR/UhpA family); similar to E. coli pleiotrophic regulation of anaerobic respiration: response regulator for nar, frd, dms and tor genes (AAC74305.1); Blastp hit to AAC74305.1 (216 aa), 96% identity in aa 1 - 216. (216 aa) |
| | fadR | Negative regulator of fad regulon; Multifunctional regulator of fatty acid metabolism. Represses transcription of at least eight genes required for fatty acid transport and beta-oxidation including fadA, fadB, fadD, fadL and fadE. Activates transcription of at least three genes required for unsaturated fatty acid biosynthesis: fabA, fabB and iclR, the gene encoding the transcriptional regulator of the aceBAK operon encoding the glyoxylate shunt enzymes. Binding of FadR is specifically inhibited by long chain fatty acyl-CoA compounds (By similarity). (239 aa) |
| | kdgR | Putative IclR family transcriptional repressor; Similar to E. coli putative regulator (AAC74897.1); Blastp hit to AAC74897.1 (263 aa), 96% identity in aa 1 - 263. (263 aa) |
| | yebK | Putative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC74923.1); Blastp hit to AAC74923.1 (289 aa), 92% identity in aa 1 - 289. (289 aa) |
| | ruvB | Holliday junction helicase, subunit B; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (336 aa) |
| | sdiA | LuxR/UhpA family; similar to E. coli transcriptional regulator of ftsQAZ gene cluster (AAC74983.1); Blastp hit to AAC74983.1 (240 aa), 71% identity in aa 1 - 240. (240 aa) |
| | rcsA | Positive transcriptional regulator of capsular/exo- polysaccharide synthesis (LuxR/UhpA family); Component of the Rcs signaling system, which controls transcription of numerous genes. Binds, with RcsB, to the RcsAB box to regulate expression of genes. (207 aa) |
| | yeeY | Similar to E. coli putative transcriptional regulator LYSR-type (AAC75076.1); Blastp hit to AAC75076.1 (316 aa), 87% identity in aa 8 - 309; Belongs to the LysR transcriptional regulatory family. (304 aa) |
| | baeR | OmpR family; similar to E. coli transcriptional response regulatory protein (sensor BaeS) (AAC75140.1); Blastp hit to AAC75140.1 (240 aa), 96% identity in aa 1 - 240. (240 aa) |
| | yegW | Putative gntR family regulatory protein; Similar to E. coli putative transcriptional regulator (AAC75162.1); Blastp hit to AAC75162.1 (248 aa), 92% identity in aa 1 - 248. (248 aa) |
| | STM2180 | Similar to E. coli putative transcriptional regulator LYSR-type (AAC74504.1); Blastp hit to AAC74504.1 (354 aa), 28% identity in aa 54 - 336; Belongs to the LysR transcriptional regulatory family. (302 aa) |
| | yeiE | Similar to E. coli putative transcriptional regulator LYSR-type (AAC75218.1); Blastp hit to AAC75218.1 (293 aa), 91% identity in aa 1 - 287; Belongs to the LysR transcriptional regulatory family. (287 aa) |
| | ada | O6-methylguanine-DNA methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated; In the C-terminal section; belongs to the MGMT family. (353 aa) |
| | rcsB | LuxR/UhpA family response regulator in two-component regulatory system with RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. Can function both in an RcsA-dependent or RcsA-independent manner. (216 aa) |
| | STM2275 | Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC74613.1); Blastp hit to AAC74613.1 (228 aa), 25% identity in aa 13 - 217. (294 aa) |
| | STM2281 | Putative LysR family transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC75298.1); Blastp hit to AAC75298.1 (68 aa), 80% identity in aa 1 - 66; Belongs to the LysR transcriptional regulatory family. (292 aa) |
| | yfaX | Similar to E. coli putative regulator (AAC75308.1); Blastp hit to AAC75308.1 (260 aa), 87% identity in aa 1 - 260. (260 aa) |
| | lrhA | Similar to E. coli NADH dehydrogenase transcriptional regulator, LysR family (AAC75349.1); Blastp hit to AAC75349.1 (312 aa), 86% identity in aa 1 - 312; Belongs to the LysR transcriptional regulatory family. (312 aa) |
| | STM2373 | Putative cytoplasmic protein. (124 aa) |
| | yfeR | Similar to E. coli putative transcriptional regulator LYSR-type (AAC75462.1); Blastp hit to AAC75462.1 (308 aa), 79% identity in aa 1 - 308; Belongs to the LysR transcriptional regulatory family. (308 aa) |
